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Items: 1 to 50 of 144

1.

Ultrahigh-throughput functional profiling of microbiota communities.

Terekhov SS, Smirnov IV, Malakhova MV, Samoilov AE, Manolov AI, Nazarov AS, Danilov DV, Dubiley SA, Osterman IA, Rubtsova MP, Kostryukova ES, Ziganshin RH, Kornienko MA, Vanyushkina AA, Bukato ON, Ilina EN, Vlasov VV, Severinov KV, Gabibov AG, Altman S.

Proc Natl Acad Sci U S A. 2018 Sep 4. pii: 201811250. doi: 10.1073/pnas.1811250115. [Epub ahead of print]

2.

Molecular Approaches to Safe and Controlled Engineered T-cell Therapy.

Kalinin RS, Petukhov AV, Knorre VD, Maschan MA, Stepanov AV, Gabibov AG.

Acta Naturae. 2018 Apr-Jun;10(2):16-23.

3.

Cloning and characterization of serpin from red king crab Paralithodes camtschaticus.

Kostin NN, Bobik TV, Shurdova EM, Ziganshin RH, Surina EA, Shagin DA, Shagina IA, Knorre VD, Isaev VA, Rudenskaya GN, Gabibov AG, Smirnov IV.

Fish Shellfish Immunol. 2018 Oct;81:99-107. doi: 10.1016/j.fsi.2018.07.014. Epub 2018 Jul 10.

PMID:
30006043
4.

Directed Change in TNFα Specificity to Create DR5 Antagonists.

Ukrainskaya VM, Bobik TV, Argentova-Stevens A, Slutskaya EA, Kalinin RS, Gabibov AG, Stepanov AV.

Bull Exp Biol Med. 2018 Jul 12. doi: 10.1007/s10517-018-4176-9. [Epub ahead of print]

PMID:
30003423
5.

Generation of Highly Specific Proteolytic Biocatalysts by Screening Technologies.

Bobik TV, Kostin NN, Knorre VD, Gabibov AG, Smirnov IV.

Bull Exp Biol Med. 2018 Jul 12. doi: 10.1007/s10517-018-4179-6. [Epub ahead of print]

PMID:
30003414
6.

A Highly Productive CHO Cell Line Secreting Human Blood Clotting Factor IX.

Kovnir SV, Orlova NA, Shakhparonov MI, Skryabin KG, Gabibov AG, Vorobiev II.

Acta Naturae. 2018 Jan-Mar;10(1):51-65.

7.

[Peculiarities of the Mechanism of Interactions of Catalytic Antibodies with Organophosphorus Substrates].

Mokrushina YA, Pipiya SO, Stepanova AV, Shamborant OG, Knorre VD, Smirnov IV, Gabibov AG, Vorobiev II.

Mol Biol (Mosk). 2017 Nov-Dec;51(6):958-968. doi: 10.7868/S0026898417060088. Russian.

8.

Death Receptors: New Opportunities in Cancer Therapy.

Ukrainskaya VM, Stepanov AV, Glagoleva IS, Knorre VD, Belogurov AAJ, Gabibov AG.

Acta Naturae. 2017 Jul-Sep;9(3):55-63.

9.

Metagenomic Analysis of Gingival Sulcus Microbiota and Pathogenesis of Periodontitis Associated with Type 2 Diabetes Mellitus.

Babaev EA, Balmasova IP, Mkrtumyan AM, Kostryukova SN, Vakhitova ES, Il'ina EN, Tsarev VN, Gabibov AG, Arutyunov SD.

Bull Exp Biol Med. 2017 Oct;163(6):718-721. doi: 10.1007/s10517-017-3888-6. Epub 2017 Oct 24.

PMID:
29063339
10.

Evolution of catalytic centers of antibodies by virtual screening of broad repertoire of mutants using supercomputer.

Golovin AV, Smirnov IV, Stepanova AV, Zalevskiy AO, Zlobin AS, Ponomarenko NA, Belogurov AA, Knorre VD, Hurs EN, Chatziefthimiou SD, Wilmanns M, Blackburn GM, Khomutov RM, Gabibov AG.

Dokl Biochem Biophys. 2017 Jul;475(1):245-249. doi: 10.1134/S1607672917040019. Epub 2017 Sep 2.

PMID:
28864894
11.

Application of Tetrameric Recombinant Human Butyrylcholinesterase as a Biopharmaceutical for Amelioration of Symptoms of Acute Organophosphate Poisoning.

Terekhov SS, Palikov VA, Palikova YA, Dyachenko IA, Shamborant OG, Smirnov IV, Masson P, Gabibov AG.

Bull Exp Biol Med. 2017 Aug;163(4):430-435. doi: 10.1007/s10517-017-3821-z. Epub 2017 Aug 29.

PMID:
28853097
12.

Evolution of inhibitor-resistant natural mutant forms of HIV-1 protease probed by pre-steady state kinetic analysis.

Zakharova MY, Kuznetsova AA, Kaliberda EN, Dronina MA, Kolesnikov AV, Kozyr AV, Smirnov IV, Rumsh LD, Fedorova OS, Knorre DG, Gabibov AG, Kuznetsov NA.

Biochimie. 2017 Nov;142:125-134. doi: 10.1016/j.biochi.2017.08.014. Epub 2017 Aug 24.

PMID:
28843613
13.

Combinatorial Screening of Peptides, Specific Ligands of Death Receptor DR5.

Ukrainskaya VM, Stepanov AV, Belogurov AA Jr, Gabibov AG.

Bull Exp Biol Med. 2017 Jul;163(3):381-384. doi: 10.1007/s10517-017-3809-8. Epub 2017 Jul 25.

PMID:
28744632
14.

Genetic Engineering of Native Chain Combinations of B-Cell Repertoires on the Surface of Methylotrophic Yeasts Pichia pastoris.

Bobik TV, Shurdova EM, Smirnov IV, Ponomarenko NA, Khurs EN, Knorre VD, Gabibov AG.

Bull Exp Biol Med. 2017 Jun;163(2):263-267. doi: 10.1007/s10517-017-3780-4. Epub 2017 Jul 18.

PMID:
28726211
15.

Approaches to Controlled Co-Amplification of Genes for Production of Biopharmaceuticals: Study of the Insertion and Amplification Dynamics of Genetic Cassettes in the Genome of Chinese Hamster Ovary Cells during Co-Expression of Compatible Pair of Plasmids.

Kovnir SV, Orlova NA, Khodak YА, Kondrashova MP, Gabibov AG, Skryabin KG, Vorobiev AI, Vorobiev II.

Bull Exp Biol Med. 2017 Jun;163(2):245-249. doi: 10.1007/s10517-017-3776-0. Epub 2017 Jul 18.

PMID:
28726207
16.

Preparation of Recombinant Serpin from Red King Crab Paralithodes сamtschaticus for Biomedical Research Purposes.

Kostin NN, Ponomarenko NA, Isaev VA, Rudenskaya GN, Bobik TV, Gabibov AG, Smirnov IV.

Bull Exp Biol Med. 2017 Jun;163(2):210-213. doi: 10.1007/s10517-017-3768-0. Epub 2017 Jul 18.

PMID:
28726206
17.

A Study of the Protective Properties of an Antibody-Based Antidote Metabolizing Organophosphorus Pesticide Paraoxon.

Mokrushina YA, Stepanova AV, Palikov VA, Stepanov AV, Belous GI, Dyachenko IA, Knorre VD, Smirnov IV, Gabibov AG.

Bull Exp Biol Med. 2017 Jun;163(2):218-221. doi: 10.1007/s10517-017-3770-6. Epub 2017 Jul 18.

PMID:
28726199
18.

Stable high-level expression of factor VIII in Chinese hamster ovary cells in improved elongation factor-1 alpha-based system.

Orlova NA, Kovnir SV, Gabibov AG, Vorobiev II.

BMC Biotechnol. 2017 Mar 24;17(1):33. doi: 10.1186/s12896-017-0353-6.

19.

Microfluidic droplet platform for ultrahigh-throughput single-cell screening of biodiversity.

Terekhov SS, Smirnov IV, Stepanova AV, Bobik TV, Mokrushina YA, Ponomarenko NA, Belogurov AA Jr, Rubtsova MP, Kartseva OV, Gomzikova MO, Moskovtsev AA, Bukatin AS, Dubina MV, Kostryukova ES, Babenko VV, Vakhitova MT, Manolov AI, Malakhova MV, Kornienko MA, Tyakht AV, Vanyushkina AA, Ilina EN, Masson P, Gabibov AG, Altman S.

Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):2550-2555. doi: 10.1073/pnas.1621226114. Epub 2017 Feb 15.

20.

Mediators and Biomarkers of Inflammation in Meningitis: Cytokine and Peptidome Profiling of Cerebrospinal Fluid.

Belogurov AA Jr, Ivanova OM, Lomakin YA, Ziganshin RH, Vaskina MI, Knorre VD, Klimova EA, Gabibov AG, Ivanov VT, Govorun VM.

Biochemistry (Mosc). 2016 Nov;81(11):1293-1302.

21.

Robotic QM/MM-driven maturation of antibody combining sites.

Smirnov IV, Golovin AV, Chatziefthimiou SD, Stepanova AV, Peng Y, Zolotareva OI, Belogurov AA Jr, Kurkova IN, Ponomarenko NA, Wilmanns M, Blackburn GM, Gabibov AG, Lerner RA.

Sci Adv. 2016 Oct 19;2(10):e1501695. eCollection 2016 Oct.

22.

Deimination of the myelin basic protein decelerates its proteasome-mediated metabolism.

Kuzina ES, Kudriaeva AA, Glagoleva IS, Knorre VD, Gabibov AG, Belogurov AA.

Dokl Biochem Biophys. 2016 Jul;469(1):277-80. doi: 10.1134/S1607672916040116. Epub 2016 Sep 7.

PMID:
27599511
23.

mRNA expression profile of mouse oligodendrocytes in inflammatory conditions.

Kudriaeva AA, Khaustova NA, Maltseva DV, Kuzina ES, Glagoleva IS, Surina EA, Knorre VD, Belogurov AA Jr, Tonevitsky AG, Gabibov AG.

Dokl Biochem Biophys. 2016 Jul;469(1):264-8. doi: 10.1134/S1607672916040086. Epub 2016 Sep 7.

PMID:
27599508
24.

Erratum to: Heterodimer HLA-DM Fused with Constant Fragment of the Heavy Chain of the Human Immunoglobulin Accelerates Influenza Hemagglutinin Peptide HA306-318 Loading to HLA-DR1.

Mamedov AE, Ponomarenko NA, Belogurov AA Jr, Gabibov AG.

Bull Exp Biol Med. 2016 Jul;161(3):442-446. No abstract available.

PMID:
27520960
25.

New Genetic Constructs for Generation of Stable Therapeutic Antibodies to Organophosphorus Toxins in Methylotrophic Yeasts Pichia Pastoris.

Mokrushina YA, Stepanova AV, Bobik TV, Smirnov IV, Gabibov AG.

Bull Exp Biol Med. 2016 May;161(1):83-7. doi: 10.1007/s10517-016-3351-0. Epub 2016 Jun 6.

PMID:
27270933
26.

[Expression Of DNA-Encoded Antidote to Organophosphorus Toxins in the Methylotrophic Yeast Pichia Pastoris].

Terekhov SS, Bobik TV, Mokrushina YA, Stepanova AV, Aleksandrova NM, Smirnov IV, Belogurov AA, Ponomarenko NA, Gabibov AG.

Prikl Biokhim Mikrobiol. 2016 Mar-Apr;52(2):184-92. Russian.

PMID:
27266247
27.

Heterodimer HLA-DM Fused with Constant Fragment of the Heavy Chain of the Human Immunoglobulin Accelerates Influenza Hemagglutinin HA306-318 Loading to HLA-DR1.

Mamedov AE, Ponomarenko NA, Belogurov AA Jr, Gabibov AG.

Bull Exp Biol Med. 2016 May;161(1):92-5. doi: 10.1007/s10517-016-3353-y. Epub 2016 Jun 6. Erratum in: Bull Exp Biol Med. 2016 Jul;161(3):442-6.

PMID:
27265131
28.

The Pathogenesis of the Demyelinating Form of Guillain-Barre Syndrome (GBS): Proteo-peptidomic and Immunological Profiling of Physiological Fluids.

Ziganshin RH, Ivanova OM, Lomakin YA, Belogurov AA Jr, Kovalchuk SI, Azarkin IV, Arapidi GP, Anikanov NA, Shender VO, Piradov MA, Suponeva NA, Vorobyeva AA, Gabibov AG, Ivanov VT, Govorun VM.

Mol Cell Proteomics. 2016 Jul;15(7):2366-78. doi: 10.1074/mcp.M115.056036. Epub 2016 May 3.

29.

Modified siRNA effectively silence inducible immunoproteasome subunits in NSO cells.

Gvozdeva OV, Belogurov AA Jr, Kuzina ES, Gabibov AG, Meschaninova MI, Ven'yaminova AG, Zenkova MA, Vlassov VV, Chernolovskaya EL.

Biochimie. 2016 Jun;125:75-82. doi: 10.1016/j.biochi.2016.02.015. Epub 2016 Mar 2.

PMID:
26944796
30.

Chemical Polysialylation and In Vivo Tetramerization Improve Pharmacokinetic Characteristics of Recombinant Human Butyrylcholinesterase-Based Bioscavengers.

Terekhov SS, Smirnov IV, Shamborant OG, Bobik TV, Ilyushin DG, Murashev AN, Dyachenko IA, Palikov VA, Knorre VD, Belogurov AA, Ponomarenko NA, Kuzina ES, Genkin DD, Masson P, Gabibov AG.

Acta Naturae. 2015 Oct-Dec;7(4):136-41.

31.

Tag7 (PGLYRP1) in Complex with Hsp70 Induces Alternative Cytotoxic Processes in Tumor Cells via TNFR1 Receptor.

Yashin DV, Ivanova OK, Soshnikova NV, Sheludchenkov AA, Romanova EA, Dukhanina EA, Tonevitsky AG, Gnuchev NV, Gabibov AG, Georgiev GP, Sashchenko LP.

J Biol Chem. 2015 Aug 28;290(35):21724-31. doi: 10.1074/jbc.M115.639732. Epub 2015 Jul 16.

32.

Specific Depletion of Myelin-Reactive B Cells via BCR-Targeting.

Stepanov AV, Belogurov AA Jr, Kothapalli P, Shamborant OG, Knorre VD, Telegin GB, Ovsepyan AA, Ponomarenko NA, Deyev SM, Kaveri SV, Gabibov AG.

Acta Naturae. 2015 Apr-Jun;7(2):74-9.

33.

Chemical Polysialylation of Recombinant Human Proteins.

Smirnov IV, Vorobiev II, Belogurov AA, Genkin DD, Deyev SM, Gabibov AG.

Methods Mol Biol. 2015;1321:389-404. doi: 10.1007/978-1-4939-2760-9_26.

PMID:
26082236
34.

Excessive Labeling Technique Provides a Highly Sensitive Fluorescent Probe for Real-time Monitoring of Biodegradation of Biopolymer Pharmaceuticals in vivo.

Terekhov SS, Smirnov IV, Shamborant OG, Zenkova MA, Chernolovskaya EL, Gladkikh DV, Murashev AN, Dyachenko IA, Knorre VD, Belogurov AA, Ponomarenko NA, Deyev SM, Vlasov VV, Gabibov AG.

Acta Naturae. 2014 Oct;6(4):54-9.

35.

Improved elongation factor-1 alpha-based vectors for stable high-level expression of heterologous proteins in Chinese hamster ovary cells.

Orlova NA, Kovnir SV, Hodak JA, Vorobiev II, Gabibov AG, Skryabin KG.

BMC Biotechnol. 2014 Jun 14;14:56. doi: 10.1186/1472-6750-14-56.

36.

Heavy-light chain interrelations of MS-associated immunoglobulins probed by deep sequencing and rational variation.

Lomakin YA, Zakharova MY, Stepanov AV, Dronina MA, Smirnov IV, Bobik TV, Pyrkov AY, Tikunova NV, Sharanova SN, Boitsov VM, Vyazmin SY, Kabilov MR, Tupikin AE, Krasnov AN, Bykova NA, Medvedeva YA, Fridman MV, Favorov AV, Ponomarenko NA, Dubina MV, Boyko AN, Vlassov VV, Belogurov AA Jr, Gabibov AG.

Mol Immunol. 2014 Dec;62(2):305-14. doi: 10.1016/j.molimm.2014.01.013. Epub 2014 Feb 16.

37.

Immunoproteasome enhances intracellular proteolysis of myelin basic protein.

Kuzina ES, Chernolovskaya EL, Kudriaeva AA, Zenkova MA, Knorre VD, Surina EA, Ponomarenko NA, Bobik TV, Smirnov IV, Bacheva AV, Belogurov AA, Gabibov AG, Vlasov VV.

Dokl Biochem Biophys. 2013 Nov;453:300-3. doi: 10.1134/S1607672913060070. Epub 2014 Jan 3. No abstract available.

PMID:
24385101
38.

Heterogeneous catalysis on the phage surface: Display of active human enteropeptidase.

Gasparian ME, Bobik TV, Kim YV, Ponomarenko NA, Dolgikh DA, Gabibov AG, Kirpichnikov MP.

Biochimie. 2013 Nov;95(11):2076-81. doi: 10.1016/j.biochi.2013.07.020. Epub 2013 Aug 3.

PMID:
23917033
39.

Blood Clotting Factor VIII: From Evolution to Therapy.

Orlova NA, Kovnir SV, Vorobiev II, Gabibov AG, Vorobiev AI.

Acta Naturae. 2013 Apr;5(2):19-39.

40.

Recombinant human butyrylcholinesterase as a new-age bioscavenger drug: development of the expression system.

Ilyushin DG, Haertley OM, Bobik TV, Shamborant OG, Surina EA, Knorre VD, Masson P, Smirnov IV, Gabibov AG, Ponomarenko NA.

Acta Naturae. 2013 Jan;5(1):73-84.

41.

Chemical polysialylation of human recombinant butyrylcholinesterase delivers a long-acting bioscavenger for nerve agents in vivo.

Ilyushin DG, Smirnov IV, Belogurov AA Jr, Dyachenko IA, Zharmukhamedova TIu, Novozhilova TI, Bychikhin EA, Serebryakova MV, Kharybin ON, Murashev AN, Anikienko KA, Nikolaev EN, Ponomarenko NA, Genkin DD, Blackburn GM, Masson P, Gabibov AG.

Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1243-8. doi: 10.1073/pnas.1211118110. Epub 2013 Jan 7.

42.

Role of Structure-Based Changes due to Somatic Mutation in Highly Homologous DNA-Binding and DNA-Hydrolyzing Autoantibodies Exemplified by A23P Substitution in the VH Domain.

Kozyr AV, Kolesnikov AV, Khlyntseva AE, Bogun AG, Savchenko GA, Shemyakin IG, Gabibov AG.

Autoimmune Dis. 2012;2012:683829. doi: 10.1155/2012/683829. Epub 2012 Nov 11.

43.

Creation of catalytic antibodies metabolizing organophosphate compounds.

Kurkova IN, Smirnov IV, Belogurov AA Jr, Ponomarenko NA, Gabibov AG.

Biochemistry (Mosc). 2012 Oct;77(10):1139-46. doi: 10.1134/S0006297912100069. Review.

44.

Liposome-encapsulated peptides protect against experimental allergic encephalitis.

Belogurov AA Jr, Stepanov AV, Smirnov IV, Melamed D, Bacon A, Mamedov AE, Boitsov VM, Sashchenko LP, Ponomarenko NA, Sharanova SN, Boyko AN, Dubina MV, Friboulet A, Genkin DD, Gabibov AG.

FASEB J. 2013 Jan;27(1):222-31. doi: 10.1096/fj.12-213975. Epub 2012 Oct 9.

45.

[Therapeutic effect of encapsulated into the nanocontainers MBP immunodominant peptides on EAE development in DA rats].

Stepanov AV, Belogurov AA, Mamedov AÉ, Melamed D, Smirnov IV, Kuzina ES, Genkin DD, Boĭko AN, Sharanova SN, Bacon A, Ponomarenko NA, Gabibov AG.

Bioorg Khim. 2012 May-Jun;38(3):306-14. Russian.

PMID:
22997702
46.

Coagulation Factor IX for Hemophilia B Therapy.

Orlova NA, Kovnir SV, Vorobiev II, Gabibov AG.

Acta Naturae. 2012 Apr;4(2):62-73.

47.

Stable Expression of Recombinant Factor VIII in CHO Cells Using Methotrexate-Driven Transgene Amplification.

Orlova NA, Kovnir SV, Vorobiev II, Yuriev AS, Gabibov AG, Vorobiev AI.

Acta Naturae. 2012 Jan;4(1):93-100.

48.

Pre-steady-state kinetics of interaction of wild-type and multiple drug-resistant HIV protease with first and second generation inhibitory drugs.

Kuznetsov NA, Kozyr AV, Dronina MA, Smirnov IV, Kaliberda EN, Mikhailova AG, Rumsh LD, Fedorova OS, Gabibov AG, Kolesnikov AV.

Dokl Biochem Biophys. 2011 Sep-Oct;440:239-43. doi: 10.1134/S1607672911050139. Epub 2011 Nov 19. No abstract available.

PMID:
22095129
49.

Combinatorial antibody library from multiple sclerosis patients reveals antibodies that cross-react with myelin basic protein and EBV antigen.

Gabibov AG, Belogurov AA Jr, Lomakin YA, Zakharova MY, Avakyan ME, Dubrovskaya VV, Smirnov IV, Ivanov AS, Molnar AA, Gurtsevitch VE, Diduk SV, Smirnova KV, Avalle B, Sharanova SN, Tramontano A, Friboulet A, Boyko AN, Ponomarenko NA, Tikunova NV.

FASEB J. 2011 Dec;25(12):4211-21. doi: 10.1096/fj.11-190769. Epub 2011 Aug 22.

PMID:
21859892
50.

Design of targeted B cell killing agents.

Stepanov AV, Belogurov AA Jr, Ponomarenko NA, Stremovskiy OA, Kozlov LV, Bichucher AM, Dmitriev SE, Smirnov IV, Shamborant OG, Balabashin DS, Sashchenko LP, Tonevitsky AG, Friboulet A, Gabibov AG, Deyev SM.

PLoS One. 2011;6(6):e20991. doi: 10.1371/journal.pone.0020991. Epub 2011 Jun 6.

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