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Items: 46


AVURT: aspirin versus placebo for the treatment of venous leg ulcers - a Phase II pilot randomised controlled trial.

Tilbrook H, Clark L, Cook L, Bland M, Buckley H, Chetter I, Dumville J, Fenner C, Forsythe R, Gabe R, Harding K, Layton A, Lindsay E, McDaid C, Moffatt C, Rolfe D, Sbizzera I, Stansby G, Torgerson D, Vowden P, Williams L, Hinchliffe R.

Health Technol Assess. 2018 Oct;22(55):1-138. doi: 10.3310/hta22550.


CAMERA - complete assessment of elderly patients with cancer: A non-randomised feasibility study.

Jackson G, Gabe R, Johnson M, Date K, Harman D, Maraveyas A, Roy R, Lind MJ.

J Geriatr Oncol. 2019 Jan;10(1):175-177. doi: 10.1016/j.jgo.2018.07.005. Epub 2018 Jul 21. No abstract available.


Multiparametric MRI to improve detection of prostate cancer compared with transrectal ultrasound-guided prostate biopsy alone: the PROMIS study.

Brown LC, Ahmed HU, Faria R, El-Shater Bosaily A, Gabe R, Kaplan RS, Parmar M, Collaco-Moraes Y, Ward K, Hindley RG, Freeman A, Kirkham A, Oldroyd R, Parker C, Bott S, Burns-Cox N, Dudderidge T, Ghei M, Henderson A, Persad R, Rosario DJ, Shergill I, Winkler M, Soares M, Spackman E, Sculpher M, Emberton M.

Health Technol Assess. 2018 Jul;22(39):1-176. doi: 10.3310/hta22390.


The safety, effectiveness and cost-effectiveness of cytisine in achieving six-month continuous smoking abstinence in tuberculosis patients-protocol for a double-blind, placebo-controlled randomized trial.

Dogar O, Barua D, Boeckmann M, Elsey H, Fatima R, Gabe R, Huque R, Keding A, Khan A, Kotz D, Kralikova E, Newell JN, Nohavova I, Parrott S, Readshaw A, Renwick L, Sheikh A, Siddiqi K; TB and Tobacco project consortium.

Addiction. 2018 Apr 20. doi: 10.1111/add.14242. [Epub ahead of print]


CollAborative care for Screen-Positive EldeRs with major depression (CASPER plus): a multicentred randomised controlled trial of clinical effectiveness and cost-effectiveness.

Bosanquet K, Adamson J, Atherton K, Bailey D, Baxter C, Beresford-Dent J, Birtwistle J, Chew-Graham C, Clare E, Delgadillo J, Ekers D, Foster D, Gabe R, Gascoyne S, Haley L, Hamilton J, Hargate R, Hewitt C, Holmes J, Keding A, Lewis H, McMillan D, Meer S, Mitchell N, Nutbrown S, Overend K, Parrott S, Pervin J, Richards DA, Spilsbury K, Torgerson D, Traviss-Turner G, Trépel D, Woodhouse R, Gilbody S.

Health Technol Assess. 2017 Nov;21(67):1-252. doi: 10.3310/hta21670.


Effect of second timed appointments for non-attenders of breast cancer screening in England: a randomised controlled trial.

Allgood PC, Maroni R, Hudson S, Offman J, Turnbull AE, Peacock L, Steel J, Kirby G, Ingram CE, Somers J, Fuller C, Threlfall AG, Gabe R, Maxwell AJ, Patnick J, Duffy SW.

Lancet Oncol. 2017 Jul;18(7):972-980. doi: 10.1016/S1470-2045(17)30340-6. Epub 2017 May 15.


A third generation vaccine for human visceral leishmaniasis and post kala azar dermal leishmaniasis: First-in-human trial of ChAd63-KH.

Osman M, Mistry A, Keding A, Gabe R, Cook E, Forrester S, Wiggins R, Di Marco S, Colloca S, Siani L, Cortese R, Smith DF, Aebischer T, Kaye PM, Lacey CJ.

PLoS Negl Trop Dis. 2017 May 12;11(5):e0005527. doi: 10.1371/journal.pntd.0005527. eCollection 2017 May.


CollAborative care and active surveillance for Screen-Positive EldeRs with subthreshold depression (CASPER): a multicentred randomised controlled trial of clinical effectiveness and cost-effectiveness.

Lewis H, Adamson J, Atherton K, Bailey D, Birtwistle J, Bosanquet K, Clare E, Delgadillo J, Ekers D, Foster D, Gabe R, Gascoyne S, Haley L, Hargate R, Hewitt C, Holmes J, Keding A, Lilley-Kelly A, Maya J, McMillan D, Meer S, Meredith J, Mitchell N, Nutbrown S, Overend K, Pasterfield M, Richards D, Spilsbury K, Torgerson D, Traviss-Turner G, Trépel D, Woodhouse R, Ziegler F, Gilbody S.

Health Technol Assess. 2017 Feb;21(8):1-196. doi: 10.3310/hta21080.


Effect of Collaborative Care vs Usual Care on Depressive Symptoms in Older Adults With Subthreshold Depression: The CASPER Randomized Clinical Trial.

Gilbody S, Lewis H, Adamson J, Atherton K, Bailey D, Birtwistle J, Bosanquet K, Clare E, Delgadillo J, Ekers D, Foster D, Gabe R, Gascoyne S, Haley L, Hamilton J, Hargate R, Hewitt C, Holmes J, Keding A, Lilley-Kelly A, Meer S, Mitchell N, Overend K, Pasterfield M, Pervin J, Richards DA, Spilsbury K, Traviss-Turner G, Trépel D, Woodhouse R, Ziegler F, McMillan D.

JAMA. 2017 Feb 21;317(7):728-737. doi: 10.1001/jama.2017.0130.


Diagnostic accuracy of multi-parametric MRI and TRUS biopsy in prostate cancer (PROMIS): a paired validating confirmatory study.

Ahmed HU, El-Shater Bosaily A, Brown LC, Gabe R, Kaplan R, Parmar MK, Collaco-Moraes Y, Ward K, Hindley RG, Freeman A, Kirkham AP, Oldroyd R, Parker C, Emberton M; PROMIS study group.

Lancet. 2017 Feb 25;389(10071):815-822. doi: 10.1016/S0140-6736(16)32401-1. Epub 2017 Jan 20.


The University College London/Medical Research Council/National Institute of Health Research-Health Technology Assessment PROMIS Trial: An Update.

El-Shater Bosaily A, Parker C, Brown LC, Gabe R, Hindley RG, Kaplan R, Emberton M, Ahmed HU; PROMIS Group.

Eur Urol Focus. 2015 Sep;1(2):212-214. No abstract available.


Aspirin for Venous Ulcers: Randomised Trial (AVURT): study protocol for a randomised controlled trial.

Tilbrook H, Forsythe RO, Rolfe D, Clark L, Bland M, Buckley H, Chetter I, Cook L, Dumville J, Gabe R, Harding K, Layton A, Lindsay E, McDaid C, Moffatt C, Phillips C, Stansby G, Vowden P, Williams L, Torgerson D, Hinchliffe RJ.

Trials. 2015 Nov 10;16:513. doi: 10.1186/s13063-015-1039-9.


Defining a New Prognostic Index for Stage I Nonseminomatous Germ Cell Tumors Using CXCL12 Expression and Proportion of Embryonal Carcinoma.

Gilbert DC, Al-Saadi R, Thway K, Chandler I, Berney D, Gabe R, Stenning SP, Sweet J, Huddart R, Shipley JM.

Clin Cancer Res. 2016 Mar 1;22(5):1265-73. doi: 10.1158/1078-0432.CCR-15-1186. Epub 2015 Oct 9.


Validation of the VEINES-QOL quality of life instrument in venous leg ulcers: repeatability and validity study embedded in a randomised clinical trial.

Bland JM, Dumville JC, Ashby RL, Gabe R, Stubbs N, Adderley U, Kang'ombe AR, Cullum NA.

BMC Cardiovasc Disord. 2015 Aug 11;15:85. doi: 10.1186/s12872-015-0080-7.


Diagnostic accuracy of the Whooley depression tool in older adults in UK primary care.

Bosanquet K, Mitchell N, Gabe R, Lewis H, McMillan D, Ekers D, Bailey D, Gilbody S.

J Affect Disord. 2015 Aug 15;182:39-43. doi: 10.1016/j.jad.2015.04.020. Epub 2015 Apr 20.


Feasibility, acceptability and validity of SMS text messaging for measuring change in depression during a randomised controlled trial.

Richmond SJ, Keding A, Hover M, Gabe R, Cross B, Torgerson D, MacPherson H.

BMC Psychiatry. 2015 Apr 3;15:68. doi: 10.1186/s12888-015-0456-3.


PROMIS--Prostate MR imaging study: A paired validating cohort study evaluating the role of multi-parametric MRI in men with clinical suspicion of prostate cancer.

El-Shater Bosaily A, Parker C, Brown LC, Gabe R, Hindley RG, Kaplan R, Emberton M, Ahmed HU; PROMIS Group.

Contemp Clin Trials. 2015 May;42:26-40. doi: 10.1016/j.cct.2015.02.008. Epub 2015 Mar 3.


Screening for psychological and mental health difficulties in young people who offend: a systematic review and decision model.

Richardson R, Trépel D, Perry A, Ali S, Duffy S, Gabe R, Gilbody S, Glanville J, Hewitt C, Manea L, Palmer S, Wright B, McMillan D.

Health Technol Assess. 2015 Jan;19(1):1-128. doi: 10.3310/hta19010. Review.


Cost-effectiveness analysis of acupuncture, counselling and usual care in treating patients with depression: the results of the ACUDep trial.

Spackman E, Richmond S, Sculpher M, Bland M, Brealey S, Gabe R, Hopton A, Keding A, Lansdown H, Perren S, Torgerson D, Watt I, MacPherson H.

PLoS One. 2014 Nov 26;9(11):e113726. doi: 10.1371/journal.pone.0113726. eCollection 2014.


VenUS IV (Venous leg Ulcer Study IV) - compression hosiery compared with compression bandaging in the treatment of venous leg ulcers: a randomised controlled trial, mixed-treatment comparison and decision-analytic model.

Ashby RL, Gabe R, Ali S, Saramago P, Chuang LH, Adderley U, Bland JM, Cullum NA, Dumville JC, Iglesias CP, Kang'ombe AR, Soares MO, Stubbs NC, Torgerson DJ.

Health Technol Assess. 2014 Sep;18(57):1-293, v-vi. doi: 10.3310/hta18570.


Patients as teachers: a randomised controlled trial on the use of personal stories of harm to raise awareness of patient safety for doctors in training.

Jha V, Buckley H, Gabe R, Kanaan M, Lawton R, Melville C, Quinton N, Symons J, Thompson Z, Watt I, Wright J.

BMJ Qual Saf. 2015 Jan;24(1):21-30. doi: 10.1136/bmjqs-2014-002987. Epub 2014 Aug 18.


A randomised phase 2 trial of intensive induction chemotherapy (CBOP/BEP) and standard BEP in poor-prognosis germ cell tumours (MRC TE23, CRUK 05/014, ISRCTN 53643604).

Huddart RA, Gabe R, Cafferty FH, Pollock P, White JD, Shamash J, Cullen MH, Stenning SP; TE23 Trial Management Group and Collaborators; National Cancer Research Institute Testis Cancer Clinical Studies Group.

Eur Urol. 2015 Mar;67(3):534-43. doi: 10.1016/j.eururo.2014.06.034. Epub 2014 Jul 4.


Therapeutic targeting of integrin αvβ6 in breast cancer.

Moore KM, Thomas GJ, Duffy SW, Warwick J, Gabe R, Chou P, Ellis IO, Green AR, Haider S, Brouilette K, Saha A, Vallath S, Bowen R, Chelala C, Eccles D, Tapper WJ, Thompson AM, Quinlan P, Jordan L, Gillett C, Brentnall A, Violette S, Weinreb PH, Kendrew J, Barry ST, Hart IR, Jones JL, Marshall JF.

J Natl Cancer Inst. 2014 Jun 28;106(8). pii: dju169. doi: 10.1093/jnci/dju169. Print 2014 Aug.


Prognostic and predictive markers in recurrent high grade glioma; results from the BR12 randomised trial.

Collins VP, Ichimura K, Di Y, Pearson D, Chan R, Thompson LC, Gabe R, Brada M, Stenning SP; BR12 Collaborators.

Acta Neuropathol Commun. 2014 Jun 20;2:68. doi: 10.1186/2051-5960-2-68.


Can virtual nature improve patient experiences and memories of dental treatment? A study protocol for a randomized controlled trial.

Tanja-Dijkstra K, Pahl S, White MP, Andrade J, May J, Stone RJ, Bruce M, Mills I, Auvray M, Gabe R, Moles DR.

Trials. 2014 Mar 22;15:90. doi: 10.1186/1745-6215-15-90.


Primary thromboprophylaxis in hospices: the association between risk of venous thromboembolism and development of symptoms.

Johnson MJ, McMillan B, Fairhurst C, Gabe R, Ward J, Wiseman J, Pollington B, Noble SI.

J Pain Symptom Manage. 2014 Jul;48(1):56-64. doi: 10.1016/j.jpainsymman.2013.08.016. Epub 2013 Dec 10.


Clinical and cost-effectiveness of compression hosiery versus compression bandages in treatment of venous leg ulcers (Venous leg Ulcer Study IV, VenUS IV): a randomised controlled trial.

Ashby RL, Gabe R, Ali S, Adderley U, Bland JM, Cullum NA, Dumville JC, Iglesias CP, Kang'ombe AR, Soares MO, Stubbs NC, Torgerson DJ.

Lancet. 2014 Mar 8;383(9920):871-9. doi: 10.1016/S0140-6736(13)62368-5. Epub 2013 Dec 6.


Acupuncture and counselling for depression in primary care: a randomised controlled trial.

MacPherson H, Richmond S, Bland M, Brealey S, Gabe R, Hopton A, Keding A, Lansdown H, Perren S, Sculpher M, Spackman E, Torgerson D, Watt I.

PLoS Med. 2013;10(9):e1001518. doi: 10.1371/journal.pmed.1001518. Epub 2013 Sep 24.


UK management practices in stage I seminoma and the Medical Research Council Trial of Imaging and Schedule in Seminoma Testis managed with surveillance.

Cafferty FH, Gabe R, Huddart RA, Rustin G, Williams MP, Stenning SP, Bara A, Bathia R, Freeman SC, Alder L, Joffe JK.

Clin Oncol (R Coll Radiol). 2012 Feb;24(1):25-9. doi: 10.1016/j.clon.2011.09.005. Epub 2011 Sep 28. No abstract available.


Carboplatin in clinical stage I seminoma: a valuable option for patient management.

Stenning S, Oliver T, Mead B, Gabe R.

J Clin Oncol. 2011 Nov 1;29(31):4210-1; author reply 4211-2. doi: 10.1200/JCO.2011.36.2434. Epub 2011 Sep 26. No abstract available.


Randomized trial of carboplatin versus radiotherapy for stage I seminoma: mature results on relapse and contralateral testis cancer rates in MRC TE19/EORTC 30982 study (ISRCTN27163214).

Oliver RT, Mead GM, Rustin GJ, Joffe JK, Aass N, Coleman R, Gabe R, Pollock P, Stenning SP.

J Clin Oncol. 2011 Mar 10;29(8):957-62. doi: 10.1200/JCO.2009.26.4655. Epub 2011 Jan 31.


Randomized trials in 2466 patients with stage I seminoma: patterns of relapse and follow-up.

Mead GM, Fossa SD, Oliver RT, Joffe JK, Huddart RA, Roberts JT, Pollock P, Gabe R, Stenning SP; MRC/EORTC seminoma trial collaborators.

J Natl Cancer Inst. 2011 Feb 2;103(3):241-9. doi: 10.1093/jnci/djq525. Epub 2011 Jan 6.


Temozolomide versus procarbazine, lomustine, and vincristine in recurrent high-grade glioma.

Brada M, Stenning S, Gabe R, Thompson LC, Levy D, Rampling R, Erridge S, Saran F, Gattamaneni R, Hopkins K, Beall S, Collins VP, Lee SM.

J Clin Oncol. 2010 Oct 20;28(30):4601-8. doi: 10.1200/JCO.2009.27.1932. Epub 2010 Sep 20.


Clinical and biological significance of CXCL12 and CXCR4 expression in adult testes and germ cell tumours of adults and adolescents.

Gilbert DC, Chandler I, McIntyre A, Goddard NC, Gabe R, Huddart RA, Shipley J.

J Pathol. 2009 Jan;217(1):94-102. doi: 10.1002/path.2436.


A case-control study to estimate the impact of the Icelandic population-based mammography screening program on breast cancer death.

Gabe R, Tryggvadóttir L, Sigfússon BF, Olafsdóttir GH, Sigurdsson K, Duffy SW.

Acta Radiol. 2007 Nov;48(9):948-55.


Avoiding bias from aggregate measures of exposure.

Duffy SW, Jonsson H, Agbaje OF, Pashayan N, Gabe R.

J Epidemiol Community Health. 2007 May;61(5):461-3.


Some issues in screening for breast and other cancers.

Duffy SW, McCann J, Godward S, Gabe R, Warwick J.

J Med Screen. 2006;13 Suppl 1:S28-34.


A dose-ranging phase I study of dextrin sulphate, a vaginal microbicide, in HIV-negative and HIV-positive female volunteers.

McCormack S, Jespers V, Low-Beer N, Gabe R, Kaganson N, Chapman A, Nunn A, Lacey C, Van Damme L.

Sex Transm Dis. 2005 Dec;32(12):765-70.


Screening for breast cancer.

Duffy SW, Smith RA, Gabe R, Tabár L, Yen AM, Chen TH.

Surg Oncol Clin N Am. 2005 Oct;14(4):671-97. Review.


Evaluation of service screening mammography in practice: the impact on breast cancer mortality.

Gabe R, Duffy SW.

Ann Oncol. 2005;16 Suppl 2:ii153-62. Review. No abstract available.


U.K. Controlled trial of intrapleural streptokinase for pleural infection.

Maskell NA, Davies CW, Nunn AJ, Hedley EL, Gleeson FV, Miller R, Gabe R, Rees GL, Peto TE, Woodhead MA, Lane DJ, Darbyshire JH, Davies RJ; First Multicenter Intrapleural Sepsis Trial (MIST1) Group.

N Engl J Med. 2005 Mar 3;352(9):865-74. Erratum in: N Engl J Med. 2005 May 19;352(20):2146.


The randomized trials of breast cancer screening: what have we learned?

Smith RA, Duffy SW, Gabe R, Tabar L, Yen AM, Chen TH.

Radiol Clin North Am. 2004 Sep;42(5):793-806, v. Review.


Dextrin sulfate as a vaginal microbicide: randomized, double-blind, placebo-controlled trial including healthy female volunteers and their male partners.

Low-Beer N, Gabe R, McCormack S, Kitchen VS, Lacey CJ, Nunn AJ.

J Acquir Immune Defic Syndr. 2002 Dec 1;31(4):391-8.


Evaluation of an exercise therapy program for patients with chronic obstructive pulmonary disease.

Nicholas JJ, Gilbert R, Gabe R, Auchincloss JH Jr.

Am Rev Respir Dis. 1970 Jul;102(1):1-9. No abstract available.


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