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Items: 24


Erythroferrone is not required for the glucoregulatory and hematologic effects of chronic erythropoietin treatment in mice.

Coffey R, Sardo U, Kautz L, Gabayan V, Nemeth E, Ganz T.

Physiol Rep. 2018 Sep;6(19):e13890. doi: 10.14814/phy2.13890.


Effects of erythropoietin on fibroblast growth factor 23 in mice and humans.

Hanudel MR, Eisenga MF, Rappaport M, Chua K, Qiao B, Jung G, Gabayan V, Gales B, Ramos G, de Jong MA, van Zanden JJ, de Borst MH, Bakker SJL, Nemeth E, Salusky IB, Gaillard CAJM, Ganz T.

Nephrol Dial Transplant. 2018 Jul 10. doi: 10.1093/ndt/gfy189. [Epub ahead of print]


Levels of the erythropoietin-responsive hormone erythroferrone in mice and humans with chronic kidney disease.

Hanudel MR, Rappaport M, Chua K, Gabayan V, Qiao B, Jung G, Salusky IB, Ganz T, Nemeth E.

Haematologica. 2018 Apr;103(4):e141-e142. doi: 10.3324/haematol.2017.181743. Epub 2018 Feb 1. No abstract available.


Endogenous hepcidin and its agonist mediate resistance to selected infections by clearing non-transferrin-bound iron.

Stefanova D, Raychev A, Arezes J, Ruchala P, Gabayan V, Skurnik M, Dillon BJ, Horwitz MA, Ganz T, Bulut Y, Nemeth E.

Blood. 2017 Jul 20;130(3):245-257. doi: 10.1182/blood-2017-03-772715. Epub 2017 May 2.


In a Mouse Model of Sepsis, Hepcidin Ablation Ameliorates Anemia More Effectively than Iron and Erythropoietin Treatment.

Khorramian E, Fung E, Chua K, Gabayan V, Ganz T, Nemeth E, Kim A.

Shock. 2017 Oct;48(4):490-497. doi: 10.1097/SHK.0000000000000886.


Erythroferrone and matriptase-2 independently regulate hepcidin expression.

Aschemeyer S, Gabayan V, Ganz T, Nemeth E, Kautz L.

Am J Hematol. 2017 May;92(5):E61-E63. doi: 10.1002/ajh.24672. Epub 2017 Feb 24. No abstract available.


Increased serum hepcidin contributes to the anemia of chronic kidney disease in a murine model.

Hanudel MR, Rappaport M, Gabayan V, Jung G, Salusky IB, Nemeth E, Ganz T, Zaritsky J.

Haematologica. 2017 Mar;102(3):e85-e88. doi: 10.3324/haematol.2016.150433. Epub 2016 Nov 24. No abstract available.


Effects of dietary iron intake and chronic kidney disease on fibroblast growth factor 23 metabolism in wild-type and hepcidin knockout mice.

Hanudel MR, Chua K, Rappaport M, Gabayan V, Valore E, Goltzman D, Ganz T, Nemeth E, Salusky IB.

Am J Physiol Renal Physiol. 2016 Dec 1;311(6):F1369-F1377. doi: 10.1152/ajprenal.00281.2016. Epub 2016 Oct 12.


Isocitrate treatment of acute anemia of inflammation in a mouse model.

Kim A, Fung E, Parikh SG, Gabayan V, Nemeth E, Ganz T.

Blood Cells Mol Dis. 2016 Jan;56(1):31-6. doi: 10.1016/j.bcmd.2015.09.007. Epub 2015 Sep 28.


Erythroferrone contributes to hepcidin suppression and iron overload in a mouse model of β-thalassemia.

Kautz L, Jung G, Du X, Gabayan V, Chapman J, Nasoff M, Nemeth E, Ganz T.

Blood. 2015 Oct 22;126(17):2031-7. doi: 10.1182/blood-2015-07-658419. Epub 2015 Aug 14.


Hepcidin-induced hypoferremia is a critical host defense mechanism against the siderophilic bacterium Vibrio vulnificus.

Arezes J, Jung G, Gabayan V, Valore E, Ruchala P, Gulig PA, Ganz T, Nemeth E, Bulut Y.

Cell Host Microbe. 2015 Jan 14;17(1):47-57. doi: 10.1016/j.chom.2014.12.001.


Mouse models of anemia of cancer.

Kim A, Rivera S, Shprung D, Limbrick D, Gabayan V, Nemeth E, Ganz T.

PLoS One. 2014 Mar 28;9(3):e93283. doi: 10.1371/journal.pone.0093283. eCollection 2014.


Hepcidin induction by pathogens and pathogen-derived molecules is strongly dependent on interleukin-6.

Rodriguez R, Jung CL, Gabayan V, Deng JC, Ganz T, Nemeth E, Bulut Y.

Infect Immun. 2014 Feb;82(2):745-52. doi: 10.1128/IAI.00983-13. Epub 2013 Dec 2.


A mouse model of anemia of inflammation: complex pathogenesis with partial dependence on hepcidin.

Kim A, Fung E, Parikh SG, Valore EV, Gabayan V, Nemeth E, Ganz T.

Blood. 2014 Feb 20;123(8):1129-36. doi: 10.1182/blood-2013-08-521419. Epub 2013 Dec 19.


Testing the iron hypothesis in a mouse model of atherosclerosis.

Kautz L, Gabayan V, Wang X, Wu J, Onwuzurike J, Jung G, Qiao B, Lusis AJ, Ganz T, Nemeth E.

Cell Rep. 2013 Dec 12;5(5):1436-42. doi: 10.1016/j.celrep.2013.11.009. Epub 2013 Dec 5.


Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice.

Ramos E, Kautz L, Rodriguez R, Hansen M, Gabayan V, Ginzburg Y, Roth MP, Nemeth E, Ganz T.

Hepatology. 2011 Apr;53(4):1333-41. doi: 10.1002/hep.24178.


Soluble hemojuvelin is released by proprotein convertase-mediated cleavage at a conserved polybasic RNRR site.

Lin L, Nemeth E, Goodnough JB, Thapa DR, Gabayan V, Ganz T.

Blood Cells Mol Dis. 2008 Jan-Feb;40(1):122-31. Epub 2007 Sep 14.


Iron transferrin regulates hepcidin synthesis in primary hepatocyte culture through hemojuvelin and BMP2/4.

Lin L, Valore EV, Nemeth E, Goodnough JB, Gabayan V, Ganz T.

Blood. 2007 Sep 15;110(6):2182-9. Epub 2007 May 31.


Suppression of hepcidin during anemia requires erythropoietic activity.

Pak M, Lopez MA, Gabayan V, Ganz T, Rivera S.

Blood. 2006 Dec 1;108(12):3730-5. Epub 2006 Aug 1.


Decreased clearance of Pseudomonas aeruginosa from airways of mice deficient in lysozyme M.

Cole AM, Thapa DR, Gabayan V, Liao HI, Liu L, Ganz T.

J Leukoc Biol. 2005 Nov;78(5):1081-5. Epub 2005 Oct 4.


Synthetic hepcidin causes rapid dose-dependent hypoferremia and is concentrated in ferroportin-containing organs.

Rivera S, Nemeth E, Gabayan V, Lopez MA, Farshidi D, Ganz T.

Blood. 2005 Sep 15;106(6):2196-9. Epub 2005 Jun 2.


Hepcidin excess induces the sequestration of iron and exacerbates tumor-associated anemia.

Rivera S, Liu L, Nemeth E, Gabayan V, Sorensen OE, Ganz T.

Blood. 2005 Feb 15;105(4):1797-802. Epub 2004 Oct 12.


IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin.

Nemeth E, Rivera S, Gabayan V, Keller C, Taudorf S, Pedersen BK, Ganz T.

J Clin Invest. 2004 May;113(9):1271-6.


Increased inflammation in lysozyme M-deficient mice in response to Micrococcus luteus and its peptidoglycan.

Ganz T, Gabayan V, Liao HI, Liu L, Oren A, Graf T, Cole AM.

Blood. 2003 Mar 15;101(6):2388-92. Epub 2002 Oct 31.

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