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Items: 1 to 50 of 77

1.

Gastrointestinal manifestation of anti-SAE dermatomyositis.

Wells M, Davies E, Gunawardena H.

Rheumatology (Oxford). 2019 Feb 19. pii: kez031. doi: 10.1093/rheumatology/kez031. [Epub ahead of print] No abstract available.

PMID:
30783675
2.

Unusual presentation of eosinophilic fasciitis (EF) with a raised ALT.

Batty T, Majeed S, Wlodek C, Gunawardena H.

BMJ Case Rep. 2018 Dec 22;11(1). pii: e227369. doi: 10.1136/bcr-2018-227369.

PMID:
30580305
3.

The effects of nonignorable missing data on label-free mass spectrometry proteomics experiments.

O'Brien JJ, Gunawardena HP, Paulo JA, Chen X, Ibrahim JG, Gygi SP, Qaqish BF.

Ann Appl Stat. 2018 Dec;12(4):2075-2095. doi: 10.1214/18-AOAS1144. Epub 2018 Nov 13.

4.

Pancytopaenia and breathlessness: Hickam's Dictum prevails!

Creamer AW, Protheroe R, Gunawardena H, Barratt SL.

Thorax. 2018 Dec;73(12):1187-1190. doi: 10.1136/thoraxjnl-2018-212088. Epub 2018 Aug 18. No abstract available.

PMID:
30121573
5.

IgG4-related pulmonary disease: the protean impersonator?

Slim D, Gunawardena H, Calvert JM, Daly RS, Plummeridge MJ, Medford AR.

J R Coll Physicians Edinb. 2018 Jun;48(2):130-133. doi: 10.4997/JRCPE.2018.207.

PMID:
29992203
6.

Rapid Screening of Ellagitannins in Natural Sources via Targeted Reporter Ion Triggered Tandem Mass Spectrometry.

Bowers JJ, Gunawardena HP, Cornu A, Narvekar AS, Richieu A, Deffieux D, Quideau S, Tharayil N.

Sci Rep. 2018 Jul 10;8(1):10399. doi: 10.1038/s41598-018-27708-3.

7.

Micro-Data-Independent Acquisition for High-Throughput Proteomics and Sensitive Peptide Mass Spectrum Identification.

Heaven MR, Cobbs AL, Nei YW, Gutierrez DB, Herren AW, Gunawardena HP, Caprioli RM, Norris JL.

Anal Chem. 2018 Aug 7;90(15):8905-8911. doi: 10.1021/acs.analchem.8b01026. Epub 2018 Jul 23.

PMID:
29984981
8.

Global Proteomic Changes Induced by the Epstein-Barr Virus Oncoproteins Latent Membrane Protein 1 and 2A.

DeKroon RM, Gunawardena HP, Edwards R, Raab-Traub N.

MBio. 2018 Jun 19;9(3). pii: e00959-18. doi: 10.1128/mBio.00959-18.

9.

Novel RNA-Affinity Proteogenomics Dissects Tumor Heterogeneity for Revealing Personalized Markers in Precision Prognosis of Cancer.

Wang L, Wrobel JA, Xie L, Li D, Zurlo G, Shen H, Yang P, Wang Z, Peng Y, Gunawardena HP, Zhang Q, Chen X.

Cell Chem Biol. 2018 May 17;25(5):619-633.e5. doi: 10.1016/j.chembiol.2018.01.016. Epub 2018 Mar 1.

10.

An unusual flare of anti-synthetase syndrome during concurrent trastuzumab therapy given for recurrent breast cancer.

Reynolds TD, Mohan V, Roy M, Manghat N, Adamali H, Gunawardena H.

Eur J Rheumatol. 2017 Dec;4(4):278-280. doi: 10.5152/eurjrheum.2017.17036. Epub 2017 Oct 25.

11.

Patterns and predictors of skin score change in early diffuse systemic sclerosis from the European Scleroderma Observational Study.

Herrick AL, Peytrignet S, Lunt M, Pan X, Hesselstrand R, Mouthon L, Silman AJ, Dinsdale G, Brown E, Czirják L, Distler JHW, Distler O, Fligelstone K, Gregory WJ, Ochiel R, Vonk MC, Ancuţa C, Ong VH, Farge D, Hudson M, Matucci-Cerinic M, Balbir-Gurman A, Midtvedt Ø, Jobanputra P, Jordan AC, Stevens W, Moinzadeh P, Hall FC, Agard C, Anderson ME, Diot E, Madhok R, Akil M, Buch MH, Chung L, Damjanov NS, Gunawardena H, Lanyon P, Ahmad Y, Chakravarty K, Jacobsen S, MacGregor AJ, McHugh N, Müller-Ladner U, Riemekasten G, Becker M, Roddy J, Carreira PE, Fauchais AL, Hachulla E, Hamilton J, İnanç M, McLaren JS, van Laar JM, Pathare S, Proudman SM, Rudin A, Sahhar J, Coppere B, Serratrice C, Sheeran T, Veale DJ, Grange C, Trad GS, Denton CP.

Ann Rheum Dis. 2018 Apr;77(4):563-570. doi: 10.1136/annrheumdis-2017-211912. Epub 2018 Jan 6.

12.

Disability, fatigue, pain and their associates in early diffuse cutaneous systemic sclerosis: the European Scleroderma Observational Study.

Peytrignet S, Denton CP, Lunt M, Hesselstrand R, Mouthon L, Silman A, Pan X, Brown E, Czirják L, Distler JHW, Distler O, Fligelstone K, Gregory WJ, Ochiel R, Vonk M, Ancuta C, Ong VH, Farge D, Hudson M, Matucci-Cerinic M, Balbir-Gurman A, Midtvedt Ø, Jordan AC, Stevens W, Moinzadeh P, Hall FC, Agard C, Anderson ME, Diot E, Madhok R, Akil M, Buch MH, Chung L, Damjanov N, Gunawardena H, Lanyon P, Ahmad Y, Chakravarty K, Jacobsen S, MacGregor AJ, McHugh N, Müller-Ladner U, Riemekasten G, Becker M, Roddy J, Carreira PE, Fauchais AL, Hachulla E, Hamilton J, Inanç M, McLaren JS, van Laar JM, Pathare S, Proudman S, Rudin A, Sahhar J, Coppere B, Serratrice C, Sheeran T, Veale DJ, Grange C, Trad GS, Herrick AL.

Rheumatology (Oxford). 2018 Feb 1;57(2):370-381. doi: 10.1093/rheumatology/kex410.

13.

Lesson of the month 2: Dry skin, yellow nails and breathlessness.

Fallon J, Majeed S, Adamali H, Gunawardena H.

Clin Med (Lond). 2017 Jul;17(4):371-372. doi: 10.7861/clinmedicine.17-4-371.

14.

Autoantibodies in juvenile-onset myositis: Their diagnostic value and associated clinical phenotype in a large UK cohort.

Tansley SL, Simou S, Shaddick G, Betteridge ZE, Almeida B, Gunawardena H, Thomson W, Beresford MW, Midgley A, Muntoni F, Wedderburn LR, McHugh NJ.

J Autoimmun. 2017 Nov;84:55-64. doi: 10.1016/j.jaut.2017.06.007. Epub 2017 Jun 26.

15.

Hematopoietic origin of Langerhans cell histiocytosis and Erdheim-Chester disease in adults.

Milne P, Bigley V, Bacon CM, Néel A, McGovern N, Bomken S, Haniffa M, Diamond EL, Durham BH, Visser J, Hunt D, Gunawardena H, Macheta M, McClain KL, Allen C, Abdel-Wahab O, Collin M.

Blood. 2017 Jul 13;130(2):167-175. doi: 10.1182/blood-2016-12-757823. Epub 2017 May 16.

16.

Corrigendum: Proteogenomic integration reveals therapeutic targets in breast cancer xenografts.

Huang KL, Li S, Mertins P, Cao S, Gunawardena HP, Ruggles KV, Mani DR, Clauser KR, Tanioka M, Usary J, Kavuri SM, Xie L, Yoon C, Qiao JW, Wrobel J, Wyczalkowski MA, Erdmann-Gilmore P, Snider JE, Hoog J, Singh P, Niu B, Guo Z, Sun SQ, Sanati S, Kawaler E, Wang X, Scott A, Ye K, McLellan MD, Wendl MC, Malovannaya A, Held JM, Gillette MA, Fenyö D, Kinsinger CR, Mesri M, Rodriguez H, Davies SR, Perou CM, Ma C, Townsend RR, Chen X, Carr SA, Ellis MJ, Ding L.

Nat Commun. 2017 Apr 25;8:15479. doi: 10.1038/ncomms15479. No abstract available.

17.

Neurological Manifestations of IgG4-Related Disease.

Baptista B, Casian A, Gunawardena H, D'Cruz D, Rice CM.

Curr Treat Options Neurol. 2017 Apr;19(4):14. doi: 10.1007/s11940-017-0450-9. Review.

18.

Row versus column correlations: avoiding the ecological fallacy in RNA/protein expression studies.

O'Brien JJ, Gunawardena HP, Qaqish BF.

Brief Bioinform. 2018 Sep 28;19(5):946-953. doi: 10.1093/bib/bbx021. Review.

19.

Proteogenomic integration reveals therapeutic targets in breast cancer xenografts.

Huang KL, Li S, Mertins P, Cao S, Gunawardena HP, Ruggles KV, Mani DR, Clauser KR, Tanioka M, Usary J, Kavuri SM, Xie L, Yoon C, Qiao JW, Wrobel J, Wyczalkowski MA, Erdmann-Gilmore P, Snider JE, Hoog J, Singh P, Niu B, Guo Z, Sun SQ, Sanati S, Kawaler E, Wang X, Scott A, Ye K, McLellan MD, Wendl MC, Malovannaya A, Held JM, Gillette MA, Fenyö D, Kinsinger CR, Mesri M, Rodriguez H, Davies SR, Perou CM, Ma C, Reid Townsend R, Chen X, Carr SA, Ellis MJ, Ding L.

Nat Commun. 2017 Mar 28;8:14864. doi: 10.1038/ncomms14864.

20.

Human herpes virus-6 encephalitis causing severe anterograde amnesia associated with rituximab, azathioprine and prednisolone combination therapy for dermatomyositis.

Baumer T, Fry C, Luppe S, Gunawardena H, Sieradzan K.

J Neurovirol. 2017 Jun;23(3):508-510. doi: 10.1007/s13365-017-0517-0. Epub 2017 Feb 21.

PMID:
28224486
21.

Treatment outcome in early diffuse cutaneous systemic sclerosis: the European Scleroderma Observational Study (ESOS).

Herrick AL, Pan X, Peytrignet S, Lunt M, Hesselstrand R, Mouthon L, Silman A, Brown E, Czirják L, Distler JHW, Distler O, Fligelstone K, Gregory WJ, Ochiel R, Vonk M, Ancuţa C, Ong VH, Farge D, Hudson M, Matucci-Cerinic M, Balbir-Gurman A, Midtvedt Ø, Jordan AC, Jobanputra P, Stevens W, Moinzadeh P, Hall FC, Agard C, Anderson ME, Diot E, Madhok R, Akil M, Buch MH, Chung L, Damjanov N, Gunawardena H, Lanyon P, Ahmad Y, Chakravarty K, Jacobsen S, MacGregor AJ, McHugh N, Müller-Ladner U, Riemekasten G, Becker M, Roddy J, Carreira PE, Fauchais AL, Hachulla E, Hamilton J, İnanç M, McLaren JS, van Laar JM, Pathare S, Proudman S, Rudin A, Sahhar J, Coppere B, Serratrice C, Sheeran T, Veale DJ, Grange C, Trad GS, Denton CP.

Ann Rheum Dis. 2017 Jul;76(7):1207-1218. doi: 10.1136/annrheumdis-2016-210503. Epub 2017 Feb 10.

22.

Comment on: Rituximab in autoimmune connective tissue disease-associated interstitial lung disease: reply.

Sharp C, Gunawardena H.

Rheumatology (Oxford). 2016 Dec;55(12):2280-2281. Epub 2016 Aug 21. No abstract available.

PMID:
27550300
23.

Rituximab in autoimmune connective tissue disease-associated interstitial lung disease.

Sharp C, McCabe M, Dodds N, Edey A, Mayers L, Adamali H, Millar AB, Gunawardena H.

Rheumatology (Oxford). 2016 Jul;55(7):1318-24. doi: 10.1093/rheumatology/kew195. Epub 2016 Apr 8.

PMID:
27060110
24.

Reproducibility of Differential Proteomic Technologies in CPTAC Fractionated Xenografts.

Tabb DL, Wang X, Carr SA, Clauser KR, Mertins P, Chambers MC, Holman JD, Wang J, Zhang B, Zimmerman LJ, Chen X, Gunawardena HP, Davies SR, Ellis MJ, Li S, Townsend RR, Boja ES, Ketchum KA, Kinsinger CR, Mesri M, Rodriguez H, Liu T, Kim S, McDermott JE, Payne SH, Petyuk VA, Rodland KD, Smith RD, Yang F, Chan DW, Zhang B, Zhang H, Zhang Z, Zhou JY, Liebler DC.

J Proteome Res. 2016 Mar 4;15(3):691-706. doi: 10.1021/acs.jproteome.5b00859. Epub 2015 Dec 22.

25.

An Analysis of the Sensitivity of Proteogenomic Mapping of Somatic Mutations and Novel Splicing Events in Cancer.

Ruggles KV, Tang Z, Wang X, Grover H, Askenazi M, Teubl J, Cao S, McLellan MD, Clauser KR, Tabb DL, Mertins P, Slebos R, Erdmann-Gilmore P, Li S, Gunawardena HP, Xie L, Liu T, Zhou JY, Sun S, Hoadley KA, Perou CM, Chen X, Davies SR, Maher CA, Kinsinger CR, Rodland KD, Zhang H, Zhang Z, Ding L, Townsend RR, Rodriguez H, Chan D, Smith RD, Liebler DC, Carr SA, Payne S, Ellis MJ, Fenyő D.

Mol Cell Proteomics. 2016 Mar;15(3):1060-71. doi: 10.1074/mcp.M115.056226. Epub 2015 Dec 2.

26.

QuantFusion: Novel Unified Methodology for Enhanced Coverage and Precision in Quantifying Global Proteomic Changes in Whole Tissues.

Gunawardena HP, O'Brien J, Wrobel JA, Xie L, Davies SR, Li S, Ellis MJ, Qaqish BF, Chen X.

Mol Cell Proteomics. 2016 Feb;15(2):740-51. doi: 10.1074/mcp.O115.049791. Epub 2015 Nov 23.

27.

The Clinical Features of Myositis-Associated Autoantibodies: a Review.

Gunawardena H.

Clin Rev Allergy Immunol. 2017 Feb;52(1):45-57. doi: 10.1007/s12016-015-8513-8. Review.

PMID:
26453338
28.

Label-free Quantitative Proteomics Reveals a Role for the Mycobacterium tuberculosis SecA2 Pathway in Exporting Solute Binding Proteins and Mce Transporters to the Cell Wall.

Feltcher ME, Gunawardena HP, Zulauf KE, Malik S, Griffin JE, Sassetti CM, Chen X, Braunstein M.

Mol Cell Proteomics. 2015 Jun;14(6):1501-16. doi: 10.1074/mcp.M114.044685. Epub 2015 Mar 26.

29.

The role of biologics in treatment of connective tissue disease-associated interstitial lung disease.

Sharp C, Dodds N, Mayers L, Millar AB, Gunawardena H, Adamali H.

QJM. 2015 Sep;108(9):683-8. doi: 10.1093/qjmed/hcv007. Epub 2015 Jan 21. Review.

PMID:
25614613
30.

A chromatin activity-based chemoproteomic approach reveals a transcriptional repressome for gene-specific silencing.

Liu C, Yu Y, Liu F, Wei X, Wrobel JA, Gunawardena HP, Zhou L, Jin J, Chen X.

Nat Commun. 2014 Dec 15;5:5733. doi: 10.1038/ncomms6733.

31.

Differentially charged isoforms of apolipoprotein E from human blood are potential biomarkers of Alzheimer's disease.

Alzate O, Osorio C, DeKroon RM, Corcimaru A, Gunawardena HP.

Alzheimers Res Ther. 2014 Jul 14;6(4):43. doi: 10.1186/alzrt273. eCollection 2014.

32.

Redox regulation of Rac1 by thiol oxidation.

Hobbs GA, Mitchell LE, Arrington ME, Gunawardena HP, DeCristo MJ, Loeser RF, Chen X, Cox AD, Campbell SL.

Free Radic Biol Med. 2015 Feb;79:237-50. doi: 10.1016/j.freeradbiomed.2014.09.027. Epub 2014 Oct 5.

33.

Anti-MDA5 autoantibodies in juvenile dermatomyositis identify a distinct clinical phenotype: a prospective cohort study.

Tansley SL, Betteridge ZE, Gunawardena H, Jacques TS, Owens CM, Pilkington C, Arnold K, Yasin S, Moraitis E, Wedderburn LR, McHugh NJ; UK Juvenile Dermatomyositis Research Group.

Arthritis Res Ther. 2014 Jul 2;16(4):R138. doi: 10.1186/ar4600.

34.

Calcinosis in juvenile dermatomyositis is influenced by both anti-NXP2 autoantibody status and age at disease onset.

Tansley SL, Betteridge ZE, Shaddick G, Gunawardena H, Arnold K, Wedderburn LR, McHugh NJ; Juvenile Dermatomyositis Research Group.

Rheumatology (Oxford). 2014 Dec;53(12):2204-8. doi: 10.1093/rheumatology/keu259. Epub 2014 Jul 1.

35.

Biophysical and proteomic characterization strategies for cysteine modifications in Ras GTPases.

Hobbs GA, Gunawardena HP, Campbell SL.

Methods Mol Biol. 2014;1120:75-96. doi: 10.1007/978-1-62703-791-4_6. Erratum in: Methods Mol Biol. 2014;1120:e1.

36.

Comparison of the membrane proteome of virulent Mycobacterium tuberculosis and the attenuated Mycobacterium bovis BCG vaccine strain by label-free quantitative proteomics.

Gunawardena HP, Feltcher ME, Wrobel JA, Gu S, Braunstein M, Chen X.

J Proteome Res. 2013 Dec 6;12(12):5463-74. doi: 10.1021/pr400334k. Epub 2013 Oct 28.

37.

The evolving spectrum of polymyositis and dermatomyositis--moving towards clinicoserological syndromes: a critical review.

Tansley S, Gunawardena H.

Clin Rev Allergy Immunol. 2014 Dec;47(3):264-73. doi: 10.1007/s12016-013-8387-6. Review.

PMID:
24048686
38.

Site-specific monoubiquitination activates Ras by impeding GTPase-activating protein function.

Hobbs GA, Gunawardena HP, Baker R, Campbell SL.

Small GTPases. 2013 Jul-Sep;4(3):186-92. doi: 10.4161/sgtp.26270. Epub 2013 Sep 12.

39.

Chronic catatonia treated with electroconvulsive therapy: a case report.

de Silva VA, Lakmini WD, Gunawardena HN, Hanwella R.

J Med Case Rep. 2013 Aug 23;7:219. doi: 10.1186/1752-1947-7-219.

40.

Modulation of B-cell exosome proteins by gamma herpesvirus infection.

Meckes DG Jr, Gunawardena HP, Dekroon RM, Heaton PR, Edwards RH, Ozgur S, Griffith JD, Damania B, Raab-Traub N.

Proc Natl Acad Sci U S A. 2013 Jul 30;110(31):E2925-33. doi: 10.1073/pnas.1303906110. Epub 2013 Jul 1.

41.

Reversible acetylation regulates acetate and propionate metabolism in Mycobacterium smegmatis.

Hayden JD, Brown LR, Gunawardena HP, Perkowski EF, Chen X, Braunstein M.

Microbiology. 2013 Sep;159(Pt 9):1986-99. doi: 10.1099/mic.0.068585-0. Epub 2013 Jun 27.

42.

Whole human genome proteogenomic mapping for ENCODE cell line data: identifying protein-coding regions.

Khatun J, Yu Y, Wrobel JA, Risk BA, Gunawardena HP, Secrest A, Spitzer WJ, Xie L, Wang L, Chen X, Giddings MC.

BMC Genomics. 2013 Feb 28;14:141. doi: 10.1186/1471-2164-14-141.

43.

Protein phosphatase 2A catalytic subunit α plays a MyD88-dependent, central role in the gene-specific regulation of endotoxin tolerance.

Xie L, Liu C, Wang L, Gunawardena HP, Yu Y, Du R, Taxman DJ, Dai P, Yan Z, Yu J, Holly SP, Parise LV, Wan YY, Ting JP, Chen X.

Cell Rep. 2013 Mar 28;3(3):678-88. doi: 10.1016/j.celrep.2013.01.029. Epub 2013 Feb 21.

44.

Glutathiolated Ras: characterization and implications for Ras activation.

Hobbs GA, Bonini MG, Gunawardena HP, Chen X, Campbell SL.

Free Radic Biol Med. 2013 Apr;57:221-9. doi: 10.1016/j.freeradbiomed.2012.10.531. Epub 2012 Oct 30.

45.

GOFAST: an integrated approach for efficient and comprehensive membrane proteome analysis.

Yu Y, Xie L, Gunawardena HP, Khatun J, Maier C, Spitzer W, Leerkes M, Giddings MC, Chen X.

Anal Chem. 2012 Nov 6;84(21):9008-14. doi: 10.1021/ac300134e. Epub 2012 Oct 25.

PMID:
23030679
46.

Long noncoding RNAs are rarely translated in two human cell lines.

Bánfai B, Jia H, Khatun J, Wood E, Risk B, Gundling WE Jr, Kundaje A, Gunawardena HP, Yu Y, Xie L, Krajewski K, Strahl BD, Chen X, Bickel P, Giddings MC, Brown JB, Lipovich L.

Genome Res. 2012 Sep;22(9):1646-57. doi: 10.1101/gr.134767.111.

47.

Landscape of transcription in human cells.

Djebali S, Davis CA, Merkel A, Dobin A, Lassmann T, Mortazavi A, Tanzer A, Lagarde J, Lin W, Schlesinger F, Xue C, Marinov GK, Khatun J, Williams BA, Zaleski C, Rozowsky J, Röder M, Kokocinski F, Abdelhamid RF, Alioto T, Antoshechkin I, Baer MT, Bar NS, Batut P, Bell K, Bell I, Chakrabortty S, Chen X, Chrast J, Curado J, Derrien T, Drenkow J, Dumais E, Dumais J, Duttagupta R, Falconnet E, Fastuca M, Fejes-Toth K, Ferreira P, Foissac S, Fullwood MJ, Gao H, Gonzalez D, Gordon A, Gunawardena H, Howald C, Jha S, Johnson R, Kapranov P, King B, Kingswood C, Luo OJ, Park E, Persaud K, Preall JB, Ribeca P, Risk B, Robyr D, Sammeth M, Schaffer L, See LH, Shahab A, Skancke J, Suzuki AM, Takahashi H, Tilgner H, Trout D, Walters N, Wang H, Wrobel J, Yu Y, Ruan X, Hayashizaki Y, Harrow J, Gerstein M, Hubbard T, Reymond A, Antonarakis SE, Hannon G, Giddings MC, Ruan Y, Wold B, Carninci P, Guigó R, Gingeras TR.

Nature. 2012 Sep 6;489(7414):101-8. doi: 10.1038/nature11233.

48.

BCLAF1 is a radiation-induced H2AX-interacting partner involved in γH2AX-mediated regulation of apoptosis and DNA repair.

Lee YY, Yu YB, Gunawardena HP, Xie L, Chen X.

Cell Death Dis. 2012 Jul 26;3:e359. doi: 10.1038/cddis.2012.76.

49.

Detection of Ras GTPase protein radicals through immuno-spin trapping.

Davis MF, Zhou L, Ehrenshaft M, Ranguelova K, Gunawardena HP, Chen X, Bonini MG, Mason RP, Campbell SL.

Free Radic Biol Med. 2012 Sep 15;53(6):1339-45. doi: 10.1016/j.freeradbiomed.2012.07.009. Epub 2012 Jul 20.

50.

In vitro phosphorylation of the focal adhesion targeting domain of focal adhesion kinase by Src kinase.

Cable J, Prutzman K, Gunawardena HP, Schaller MD, Chen X, Campbell SL.

Biochemistry. 2012 Mar 20;51(11):2213-23. doi: 10.1021/bi300123a. Epub 2012 Mar 8.

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