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Items: 1 to 50 of 97

1.

Azithromycin induces epidermal differentiation and multivesicular bodies in airway epithelia.

Arason AJ, Joelsson JP, Valdimarsdottir B, Sigurdsson S, Gudjonsson A, Halldorsson S, Johannsson F, Rolfsson O, Lehmann F, Ingthorsson S, Cherek P, Gudmundsson GH, Gardarsson FR, Page CP, Baldursson O, Gudjonsson T, Kricker JA.

Respir Res. 2019 Jun 24;20(1):129. doi: 10.1186/s12931-019-1101-3.

2.

Innovative in vitro method to study ventilator induced lung injury.

Joelsson JP, Myszor IT, Arason AJ, Ingthorsson S, Cherek P, Windels GS, Leosson K, Gudmundsson GH, Gudjonsson T, Karason S.

ALTEX. 2019 Jun 5. doi: 10.14573/altex.1901182. [Epub ahead of print]

3.

Novel aroylated phenylenediamine compounds enhance antimicrobial defense and maintain airway epithelial barrier integrity.

Myszor IT, Parveen Z, Ottosson H, Bergman P, Agerberth B, Strömberg R, Gudmundsson GH.

Sci Rep. 2019 May 8;9(1):7114. doi: 10.1038/s41598-019-43350-z.

4.

Comment on "Friction at the bed does not control fast glacier flow".

Minchew BM, Meyer CR, Pegler SS, Lipovsky BP, Rempel AW, Gudmundsson GH, Iverson NR.

Science. 2019 Feb 8;363(6427). pii: eaau6055. doi: 10.1126/science.aau6055.

PMID:
30733388
5.

A novel cysteine-linked antibacterial surface coating significantly inhibits bacterial colonization of nasal silicone prongs in a phase one pre-clinical trial.

Odeberg J, Wirsén A, Norberg Å, Frie J, Printz G, Lagercrantz H, Gudmundsson GH, Agerberth B, Jonsson B.

Mater Sci Eng C Mater Biol Appl. 2018 Dec 1;93:782-789. doi: 10.1016/j.msec.2018.08.040. Epub 2018 Aug 23.

PMID:
30274112
6.

Immune responses in the treatment of drug-sensitive pulmonary tuberculosis with phenylbutyrate and vitamin D3 as host directed therapy.

Rekha RS, Mily A, Sultana T, Haq A, Ahmed S, Mostafa Kamal SM, van Schadewijk A, Hiemstra PS, Gudmundsson GH, Agerberth B, Raqib R.

BMC Infect Dis. 2018 Jul 4;18(1):303. doi: 10.1186/s12879-018-3203-9.

7.

Lactose Induces Phenotypic and Functional Changes of Neutrophils and Macrophages to Alleviate Acute Pancreatitis in Mice.

Pan LL, Deng YY, Wang R, Wu C, Li J, Niu W, Yang Q, Bhatia M, Gudmundsson GH, Agerberth B, Diana J, Sun J.

Front Immunol. 2018 Apr 17;9:751. doi: 10.3389/fimmu.2018.00751. eCollection 2018.

8.

Bordetella pertussis Adenylate Cyclase Toxin Disrupts Functional Integrity of Bronchial Epithelial Layers.

Hasan S, Kulkarni NN, Asbjarnarson A, Linhartova I, Osicka R, Sebo P, Gudmundsson GH.

Infect Immun. 2018 Feb 20;86(3). pii: e00445-17. doi: 10.1128/IAI.00445-17. Print 2018 Mar.

9.

Treatment with Entinostat Heals Experimental Cholera by Affecting Physical and Chemical Barrier Functions of Intestinal Epithelia.

Sarker P, Banik A, Stromberg R, Gudmundsson GH, Raqib R, Agerberth B.

Antimicrob Agents Chemother. 2017 Jun 27;61(7). pii: e02570-16. doi: 10.1128/AAC.02570-16. Print 2017 Jul.

10.

Assays for Identifying Inducers of the Antimicrobial Peptide LL-37.

Nylén F, Bergman P, Gudmundsson GH, Agerberth B.

Methods Mol Biol. 2017;1548:271-281. doi: 10.1007/978-1-4939-6737-7_19.

PMID:
28013511
11.

Potent Inducers of Endogenous Antimicrobial Peptides for Host Directed Therapy of Infections.

Ottosson H, Nylén F, Sarker P, Miraglia E, Bergman P, Gudmundsson GH, Raqib R, Agerberth B, Strömberg R.

Sci Rep. 2016 Nov 9;6:36692. doi: 10.1038/srep36692.

12.

Entinostat up-regulates the CAMP gene encoding LL-37 via activation of STAT3 and HIF-1α transcription factors.

Miraglia E, Nylén F, Johansson K, Arnér E, Cebula M, Farmand S, Ottosson H, Strömberg R, Gudmundsson GH, Agerberth B, Bergman P.

Sci Rep. 2016 Sep 16;6:33274. doi: 10.1038/srep33274.

13.

Cyclic mechanical stretch down-regulates cathelicidin antimicrobial peptide expression and activates a pro-inflammatory response in human bronchial epithelial cells.

Karadottir H, Kulkarni NN, Gudjonsson T, Karason S, Gudmundsson GH.

PeerJ. 2015 Dec 7;3:e1483. doi: 10.7717/peerj.1483. eCollection 2015.

14.

Cathelicidins positively regulate pancreatic β-cell functions.

Sun J, Xu M, Ortsäter H, Lundeberg E, Juntti-Berggren L, Chen YQ, Haeggström JZ, Gudmundsson GH, Diana J, Agerberth B.

FASEB J. 2016 Feb;30(2):884-94. doi: 10.1096/fj.15-275826. Epub 2015 Nov 2.

PMID:
26527065
15.

Significant Effects of Oral Phenylbutyrate and Vitamin D3 Adjunctive Therapy in Pulmonary Tuberculosis: A Randomized Controlled Trial.

Mily A, Rekha RS, Kamal SM, Arifuzzaman AS, Rahim Z, Khan L, Haq MA, Zaman K, Bergman P, Brighenti S, Gudmundsson GH, Agerberth B, Raqib R.

PLoS One. 2015 Sep 22;10(9):e0138340. doi: 10.1371/journal.pone.0138340. eCollection 2015.

16.

Glucocorticoid dexamethasone down-regulates basal and vitamin D3 induced cathelicidin expression in human monocytes and bronchial epithelial cell line.

Kulkarni NN, Gunnarsson HI, Yi Z, Gudmundsdottir S, Sigurjonsson OE, Agerberth B, Gudmundsson GH.

Immunobiology. 2016 Feb;221(2):245-52. doi: 10.1016/j.imbio.2015.09.001. Epub 2015 Sep 3.

PMID:
26358366
17.

Phenylbutyrate induces LL-37-dependent autophagy and intracellular killing of Mycobacterium tuberculosis in human macrophages.

Rekha RS, Rao Muvva SS, Wan M, Raqib R, Bergman P, Brighenti S, Gudmundsson GH, Agerberth B.

Autophagy. 2015;11(9):1688-99. doi: 10.1080/15548627.2015.1075110.

18.

Phenylbutyrate induces cathelicidin expression via the vitamin D receptor: Linkage to inflammatory and growth factor cytokines pathways.

Kulkarni NN, Yi Z, Huehnken C, Agerberth B, Gudmundsson GH.

Mol Immunol. 2015 Feb;63(2):530-9.

PMID:
25458314
19.

A review of the innate immune defence of the human foetus and newborn, with the emphasis on antimicrobial peptides.

Kai-Larsen Y, Gudmundsson GH, Agerberth B.

Acta Paediatr. 2014 Oct;103(10):1000-8. doi: 10.1111/apa.12700. Epub 2014 Jun 23. Review.

PMID:
24861898
20.

Ciprofloxacin Affects Host Cells by Suppressing Expression of the Endogenous Antimicrobial Peptides Cathelicidins and Beta-Defensin-3 in Colon Epithelia.

Sarker P, Mily A, Mamun AA, Jalal S, Bergman P, Raqib R, Gudmundsson GH, Agerberth B.

Antibiotics (Basel). 2014 Jul 25;3(3):353-74. doi: 10.3390/antibiotics3030353.

21.

Label-free quantitative mass spectrometry reveals novel pathways involved in LL-37 expression.

Cederlund A, Nylén F, Miraglia E, Bergman P, Gudmundsson GH, Agerberth B.

J Innate Immun. 2014;6(3):365-76. doi: 10.1159/000355931. Epub 2013 Nov 16.

22.

Treatment with phenylbutyrate in a pre-clinical trial reduces diarrhea due to enteropathogenic Escherichia coli: link to cathelicidin induction.

Al-Mamun A, Mily A, Sarker P, Tiash S, Navarro A, Akter M, Talukder KA, Islam MF, Agerberth B, Gudmundsson GH, Cravioto A, Raqib R.

Microbes Infect. 2013 Nov;15(13):939-50. doi: 10.1016/j.micinf.2013.08.007. Epub 2013 Sep 7.

PMID:
24016414
23.

Boosting innate immunity: development and validation of a cell-based screening assay to identify LL-37 inducers.

Nylén F, Miraglia E, Cederlund A, Ottosson H, Strömberg R, Gudmundsson GH, Agerberth B.

Innate Immun. 2014 May;20(4):364-76. doi: 10.1177/1753425913493338. Epub 2013 Jul 24.

PMID:
23884095
24.

Gatekeeping and referrals to cardiologists: general practitioners' views on interactive communications.

Bjornsson S, Sigurdsson JA, Svavarsdottir AE, Gudmundsson GH.

Scand J Prim Health Care. 2013 Jun;31(2):79-82. doi: 10.3109/02813432.2013.784543. Epub 2013 Apr 23.

25.

Oral intake of phenylbutyrate with or without vitamin D3 upregulates the cathelicidin LL-37 in human macrophages: a dose finding study for treatment of tuberculosis.

Mily A, Rekha RS, Kamal SM, Akhtar E, Sarker P, Rahim Z, Gudmundsson GH, Agerberth B, Raqib R.

BMC Pulm Med. 2013 Apr 16;13:23. doi: 10.1186/1471-2466-13-23.

26.

Lactose in human breast milk an inducer of innate immunity with implications for a role in intestinal homeostasis.

Cederlund A, Kai-Larsen Y, Printz G, Yoshio H, Alvelius G, Lagercrantz H, Strömberg R, Jörnvall H, Gudmundsson GH, Agerberth B.

PLoS One. 2013;8(1):e53876. doi: 10.1371/journal.pone.0053876. Epub 2013 Jan 10.

27.

Efficacy of sodium butyrate adjunct therapy in shigellosis: a randomized, double-blind, placebo-controlled clinical trial.

Raqib R, Sarker P, Mily A, Alam NH, Arifuzzaman AS, Rekha RS, Andersson J, Gudmundsson GH, Cravioto A, Agerberth B.

BMC Infect Dis. 2012 May 10;12:111.

28.

The anti-microbial peptide LL-37 modulates immune responses in the palatine tonsils where it is exclusively expressed by neutrophils and a subset of dendritic cells.

Sigurdardottir SL, Thorleifsdottir RH, Guzman AM, Gudmundsson GH, Valdimarsson H, Johnston A.

Clin Immunol. 2012 Feb;142(2):139-49. doi: 10.1016/j.clim.2011.09.013. Epub 2011 Oct 7.

PMID:
22036268
29.

Functional characterization of codCath, the mature cathelicidin antimicrobial peptide from Atlantic cod (Gadus morhua).

Broekman DC, Zenz A, Gudmundsdottir BK, Lohner K, Maier VH, Gudmundsson GH.

Peptides. 2011 Oct;32(10):2044-51. doi: 10.1016/j.peptides.2011.09.012. Epub 2011 Sep 16.

PMID:
21945422
30.

Antimicrobial peptides important in innate immunity.

Cederlund A, Gudmundsson GH, Agerberth B.

FEBS J. 2011 Oct;278(20):3942-51. doi: 10.1111/j.1742-4658.2011.08302.x. Epub 2011 Sep 19. Review.

31.

Phenylbutyrate counteracts Shigella mediated downregulation of cathelicidin in rabbit lung and intestinal epithelia: a potential therapeutic strategy.

Sarker P, Ahmed S, Tiash S, Rekha RS, Stromberg R, Andersson J, Bergman P, Gudmundsson GH, Agerberth B, Raqib R.

PLoS One. 2011;6(6):e20637. doi: 10.1371/journal.pone.0020637. Epub 2011 Jun 3.

32.

Cod cathelicidin: isolation of the mature peptide, cleavage site characterisation and developmental expression.

Broekman DC, Frei DM, Gylfason GA, Steinarsson A, Jörnvall H, Agerberth B, Gudmundsson GH, Maier VH.

Dev Comp Immunol. 2011 Mar;35(3):296-303. doi: 10.1016/j.dci.2010.10.002. Epub 2010 Oct 20.

PMID:
20950641
33.

Battle and balance at mucosal surfaces--the story of Shigella and antimicrobial peptides.

Gudmundsson GH, Bergman P, Andersson J, Raqib R, Agerberth B.

Biochem Biophys Res Commun. 2010 May 21;396(1):116-9. doi: 10.1016/j.bbrc.2010.03.081. Review.

PMID:
20494122
34.

[Gatekeeping and referrals from GPs to cardiologists: patients' opinions and registration of information flow].

Björnsson S, Sigurdsson JA, Svavarsdóttir AE, Gudmundsson GH.

Laeknabladid. 2010 May;96(5):335-40. Icelandic.

PMID:
20445220
35.

Phenylbutyrate induces antimicrobial peptide expression.

Steinmann J, Halldórsson S, Agerberth B, Gudmundsson GH.

Antimicrob Agents Chemother. 2009 Dec;53(12):5127-33. doi: 10.1128/AAC.00818-09. Epub 2009 Sep 21.

36.

Azithromycin maintains airway epithelial integrity during Pseudomonas aeruginosa infection.

Halldorsson S, Gudjonsson T, Gottfredsson M, Singh PK, Gudmundsson GH, Baldursson O.

Am J Respir Cell Mol Biol. 2010 Jan;42(1):62-8. doi: 10.1165/rcmb.2008-0357OC. Epub 2009 Apr 16.

PMID:
19372247
37.

[Natural immunity--first line defense. New treatment against infections and autoimmune diseases in sight].

Bergman P, Gudmundsson GH, Agerberth B.

Lakartidningen. 2008 Aug 20-26;105(34):2254-9. Review. Swedish. No abstract available.

PMID:
18785598
38.

PU.1 and bacterial metabolites regulate the human gene CAMP encoding antimicrobial peptide LL-37 in colon epithelial cells.

Termén S, Tollin M, Rodriguez E, Sveinsdóttir SH, Jóhannesson B, Cederlund A, Sjövall J, Agerberth B, Gudmundsson GH.

Mol Immunol. 2008 Sep;45(15):3947-55. doi: 10.1016/j.molimm.2008.06.020. Epub 2008 Jul 26.

PMID:
18657865
39.

Characterisation of cathelicidin gene family members in divergent fish species.

Maier VH, Dorn KV, Gudmundsdottir BK, Gudmundsson GH.

Mol Immunol. 2008 Aug;45(14):3723-30. doi: 10.1016/j.molimm.2008.06.002. Epub 2008 Jul 9.

PMID:
18614236
40.

Bacterial DNA indicated as an important inducer of fish cathelicidins.

Maier VH, Schmitt CN, Gudmundsdottir S, Gudmundsson GH.

Mol Immunol. 2008 Apr;45(8):2352-8. doi: 10.1016/j.molimm.2007.11.008. Epub 2007 Dec 27.

PMID:
18164061
41.

Differentiation potential of a basal epithelial cell line established from human bronchial explant.

Halldorsson S, Asgrimsson V, Axelsson I, Gudmundsson GH, Steinarsdottir M, Baldursson O, Gudjonsson T.

In Vitro Cell Dev Biol Anim. 2007 Sep-Oct;43(8-9):283-9. Epub 2007 Sep 18.

PMID:
17876679
42.

Antimicrobial components of the neonatal gut affected upon colonization.

Kai-Larsen Y, Bergsson G, Gudmundsson GH, Printz G, Jörnvall H, Marchini G, Agerberth B.

Pediatr Res. 2007 May;61(5 Pt 1):530-6.

PMID:
17413858
43.

Fortnightly variations in the flow velocity of Rutford Ice Stream, West Antarctica.

Gudmundsson GH.

Nature. 2006 Dec 21;444(7122):1063-4.

PMID:
17183321
44.

Induction of the antimicrobial peptide CRAMP in the blood-brain barrier and meninges after meningococcal infection.

Bergman P, Johansson L, Wan H, Jones A, Gallo RL, Gudmundsson GH, Hökfelt T, Jonsson AB, Agerberth B.

Infect Immun. 2006 Dec;74(12):6982-91. Epub 2006 Oct 9.

45.

Host antimicrobial defence peptides in human disease.

Agerberth B, Gudmundsson GH.

Curr Top Microbiol Immunol. 2006;306:67-90. Review.

PMID:
16909918
46.

Antimicrobial peptide LL-37 internalized by immature human dendritic cells alters their phenotype.

Bandholtz L, Ekman GJ, Vilhelmsson M, Buentke E, Agerberth B, Scheynius A, Gudmundsson GH.

Scand J Immunol. 2006 Jun;63(6):410-9.

47.

The antimicrobial peptide cathelicidin protects the urinary tract against invasive bacterial infection.

Chromek M, Slamová Z, Bergman P, Kovács L, Podracká L, Ehrén I, Hökfelt T, Gudmundsson GH, Gallo RL, Agerberth B, Brauner A.

Nat Med. 2006 Jun;12(6):636-41. Epub 2006 Jun 4.

PMID:
16751768
48.

Improved outcome in shigellosis associated with butyrate induction of an endogenous peptide antibiotic.

Raqib R, Sarker P, Bergman P, Ara G, Lindh M, Sack DA, Nasirul Islam KM, Gudmundsson GH, Andersson J, Agerberth B.

Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9178-83. Epub 2006 Jun 1.

49.

Involvement of the antimicrobial peptide LL-37 in human atherosclerosis.

Edfeldt K, Agerberth B, Rottenberg ME, Gudmundsson GH, Wang XB, Mandal K, Xu Q, Yan ZQ.

Arterioscler Thromb Vasc Biol. 2006 Jul;26(7):1551-7. Epub 2006 Apr 27.

PMID:
16645154
50.

Novel effects of azithromycin on tight junction proteins in human airway epithelia.

Asgrimsson V, Gudjonsson T, Gudmundsson GH, Baldursson O.

Antimicrob Agents Chemother. 2006 May;50(5):1805-12.

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