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Best matches for GRÄSLUND A[au]:

Cytosolic antibody delivery by lipid-sensitive endosomolytic peptide. Akishiba M et al. Nat Chem. (2017)

Zinc as chaperone-mimicking agent for retardation of amyloid β peptide fibril formation. Abelein A et al. Proc Natl Acad Sci U S A. (2015)

Effects of in vivo conditions on amyloid aggregation. Owen MC et al. Chem Soc Rev. (2019)

Search results

Items: 1 to 50 of 299

1.

Solvent-Assisted Paper Spray Ionization Mass Spectrometry (SAPSI-MS) for the Analysis of Biomolecules and Biofluids.

Riboni N, Quaranta A, Motwani HV, Österlund N, Gräslund A, Bianchi F, Ilag LL.

Sci Rep. 2019 Jul 16;9(1):10296. doi: 10.1038/s41598-019-45358-x.

2.

Pro-Inflammatory S100A9 Protein Aggregation Promoted by NCAM1 Peptide Constructs.

Pansieri J, Ostojić L, Iashchishyn IA, Magzoub M, Wallin C, Wärmländer SKTS, Gräslund A, Nguyen Ngoc M, Smirnovas V, Svedružić Ž, Morozova-Roche LA.

ACS Chem Biol. 2019 Jul 19;14(7):1410-1417. doi: 10.1021/acschembio.9b00394. Epub 2019 Jun 13.

PMID:
31194501
3.

Effects of in vivo conditions on amyloid aggregation.

Owen MC, Gnutt D, Gao M, Wärmländer SKTS, Jarvet J, Gräslund A, Winter R, Ebbinghaus S, Strodel B.

Chem Soc Rev. 2019 Jul 15;48(14):3946-3996. doi: 10.1039/c8cs00034d. Review.

PMID:
31192324
4.

Native Ion Mobility-Mass Spectrometry Reveals the Formation of β-Barrel Shaped Amyloid-β Hexamers in a Membrane-Mimicking Environment.

Österlund N, Moons R, Ilag LL, Sobott F, Gräslund A.

J Am Chem Soc. 2019 Jul 3;141(26):10440-10450. doi: 10.1021/jacs.9b04596. Epub 2019 Jun 19.

5.

Role of hydrophobic residues for the gaseous formation of helical motifs.

Liu L, Dong X, Liu Y, Österlund N, Gräslund A, Carloni P, Li J.

Chem Commun (Camb). 2019 Apr 25;55(35):5147-5150. doi: 10.1039/c9cc01898k.

PMID:
30977489
6.

Amyloidogenic Nanoplaques in Blood Serum of Patients with Alzheimer's Disease Revealed by Time-Resolved Thioflavin T Fluorescence Intensity Fluctuation Analysis.

Tiiman A, Jelić V, Jarvet J, Järemo P, Bogdanović N, Rigler R, Terenius L, Gräslund A, Vukojević V.

J Alzheimers Dis. 2019;68(2):571-582. doi: 10.3233/JAD-181144.

7.

Copper ions induce dityrosine-linked dimers in human but not in murine islet amyloid polypeptide (IAPP/amylin).

Dong X, Svantesson T, Sholts SB, Wallin C, Jarvet J, Gräslund A, Wärmländer SKTS.

Biochem Biophys Res Commun. 2019 Mar 19;510(4):520-524. doi: 10.1016/j.bbrc.2019.01.120. Epub 2019 Feb 6.

PMID:
30737030
8.

Photoactive chlorin e6 is a multifunctional modulator of amyloid-β aggregation and toxicity via specific interactions with its histidine residues.

Leshem G, Richman M, Lisniansky E, Antman-Passig M, Habashi M, Gräslund A, Wärmländer SKTS, Rahimipour S.

Chem Sci. 2018 Oct 3;10(1):208-217. doi: 10.1039/c8sc01992d. eCollection 2019 Jan 7.

9.

Membrane-mimetic systems for biophysical studies of the amyloid-β peptide.

Österlund N, Luo J, Wärmländer SKTS, Gräslund A.

Biochim Biophys Acta Proteins Proteom. 2019 May;1867(5):492-501. doi: 10.1016/j.bbapap.2018.11.005. Epub 2018 Nov 22. Review.

PMID:
30468884
10.

Co-aggregation of pro-inflammatory S100A9 with α-synuclein in Parkinson's disease: ex vivo and in vitro studies.

Horvath I, Iashchishyn IA, Moskalenko RA, Wang C, Wärmländer SKTS, Wallin C, Gräslund A, Kovacs GG, Morozova-Roche LA.

J Neuroinflammation. 2018 Jun 4;15(1):172. doi: 10.1186/s12974-018-1210-9.

11.

The Neuronal Tau Protein Blocks in Vitro Fibrillation of the Amyloid-β (Aβ) Peptide at the Oligomeric Stage.

Wallin C, Hiruma Y, Wärmländer SKTS, Huvent I, Jarvet J, Abrahams JP, Gräslund A, Lippens G, Luo J.

J Am Chem Soc. 2018 Jul 5;140(26):8138-8146. doi: 10.1021/jacs.7b13623. Epub 2018 May 22.

PMID:
29708745
12.

Amyloid-β Peptide Interactions with Amphiphilic Surfactants: Electrostatic and Hydrophobic Effects.

Österlund N, Kulkarni YS, Misiaszek AD, Wallin C, Krüger DM, Liao Q, Mashayekhy Rad F, Jarvet J, Strodel B, Wärmländer SKTS, Ilag LL, Kamerlin SCL, Gräslund A.

ACS Chem Neurosci. 2018 Jul 18;9(7):1680-1692. doi: 10.1021/acschemneuro.8b00065. Epub 2018 May 4.

PMID:
29683649
13.

Mechanism of Peptide Binding and Cleavage by the Human Mitochondrial Peptidase Neurolysin.

Teixeira PF, Masuyer G, Pinho CM, Branca RMM, Kmiec B, Wallin C, Wärmländer SKTS, Berntsson RP, Ankarcrona M, Gräslund A, Lehtiö J, Stenmark P, Glaser E.

J Mol Biol. 2018 Feb 2;430(3):348-362. doi: 10.1016/j.jmb.2017.11.011. Epub 2017 Nov 26.

PMID:
29183787
14.

Alzheimer's disease and cigarette smoke components: effects of nicotine, PAHs, and Cd(II), Cr(III), Pb(II), Pb(IV) ions on amyloid-β peptide aggregation.

Wallin C, Sholts SB, Österlund N, Luo J, Jarvet J, Roos PM, Ilag L, Gräslund A, Wärmländer SKTS.

Sci Rep. 2017 Oct 31;7(1):14423. doi: 10.1038/s41598-017-13759-5.

15.

Cytosolic antibody delivery by lipid-sensitive endosomolytic peptide.

Akishiba M, Takeuchi T, Kawaguchi Y, Sakamoto K, Yu HH, Nakase I, Takatani-Nakase T, Madani F, Gräslund A, Futaki S.

Nat Chem. 2017 Aug;9(8):751-761. doi: 10.1038/nchem.2779. Epub 2017 May 22.

PMID:
28754944
16.

Cross-interactions between the Alzheimer disease amyloid-β peptide and other amyloid proteins. A FURTHER ASPECT OF THE AMYLOID CASCADE HYPOTHESIS.

Luo J, Wärmländer SK, Gräslund A, Abrahams JP.

J Biol Chem. 2017 Feb 3;292(5):2046. doi: 10.1074/jbc.A116.714576. Epub 2017 Feb 3. No abstract available.

17.

Specific Binding of Cu(II) Ions to Amyloid-Beta Peptides Bound to Aggregation-Inhibiting Molecules or SDS Micelles Creates Complexes that Generate Radical Oxygen Species.

Tiiman A, Luo J, Wallin C, Olsson L, Lindgren J, Jarvet J, Per R, Sholts SB, Rahimipour S, Abrahams JP, Karlström AE, Gräslund A, Wärmländer SK.

J Alzheimers Dis. 2016 Oct 4;54(3):971-982.

PMID:
27567855
18.

Self-Assembled Cyclic d,l-α-Peptides as Generic Conformational Inhibitors of the α-Synuclein Aggregation and Toxicity: In Vitro and Mechanistic Studies.

Chemerovski-Glikman M, Rozentur-Shkop E, Richman M, Grupi A, Getler A, Cohen HY, Shaked H, Wallin C, Wärmländer SK, Haas E, Gräslund A, Chill JH, Rahimipour S.

Chemistry. 2016 Sep 26;22(40):14236-46. doi: 10.1002/chem.201601830. Epub 2016 Aug 19.

PMID:
27539220
19.

Cross-interactions between the Alzheimer Disease Amyloid-β Peptide and Other Amyloid Proteins: A Further Aspect of the Amyloid Cascade Hypothesis.

Luo J, Wärmländer SK, Gräslund A, Abrahams JP.

J Biol Chem. 2016 Aug 5;291(32):16485-93. doi: 10.1074/jbc.R116.714576. Epub 2016 Jun 20. Review. Erratum in: J Biol Chem. 2017 Feb 3;292(5):2046.

20.

Ionic Strength Modulation of the Free Energy Landscape of Aβ40 Peptide Fibril Formation.

Abelein A, Jarvet J, Barth A, Gräslund A, Danielsson J.

J Am Chem Soc. 2016 Jun 1;138(21):6893-902. doi: 10.1021/jacs.6b04511. Epub 2016 May 23.

PMID:
27171340
21.

Characterization of Mn(II) ion binding to the amyloid-β peptide in Alzheimer's disease.

Wallin C, Kulkarni YS, Abelein A, Jarvet J, Liao Q, Strodel B, Olsson L, Luo J, Abrahams JP, Sholts SB, Roos PM, Kamerlin SC, Gräslund A, Wärmländer SK.

J Trace Elem Med Biol. 2016 Dec;38:183-193. doi: 10.1016/j.jtemb.2016.03.009. Epub 2016 Mar 18.

PMID:
27085215
22.

Reciprocal Molecular Interactions between the Aβ Peptide Linked to Alzheimer's Disease and Insulin Linked to Diabetes Mellitus Type II.

Luo J, Wärmländer SK, Gräslund A, Abrahams JP.

ACS Chem Neurosci. 2016 Mar 16;7(3):269-74. doi: 10.1021/acschemneuro.5b00325. Epub 2016 Jan 27.

PMID:
26785771
23.

Heterogeneity and Turnover of Intermediates during Amyloid-β (Aβ) Peptide Aggregation Studied by Fluorescence Correlation Spectroscopy.

Tiiman A, Jarvet J, Gräslund A, Vukojević V.

Biochemistry. 2015 Dec 15;54(49):7203-11. doi: 10.1021/acs.biochem.5b00976. Epub 2015 Dec 3.

PMID:
26574169
24.

Investigating Membrane Interactions and Structures of CPPs.

Madani F, Gräslund A.

Methods Mol Biol. 2015;1324:73-87. doi: 10.1007/978-1-4939-2806-4_5.

PMID:
26202263
25.

Zinc as chaperone-mimicking agent for retardation of amyloid β peptide fibril formation.

Abelein A, Gräslund A, Danielsson J.

Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):5407-12. doi: 10.1073/pnas.1421961112. Epub 2015 Mar 30.

26.

Targeting prion propagation using peptide constructs with signal sequence motifs.

Söderberg KL, Guterstam P, Langel U, Gräslund A.

Arch Biochem Biophys. 2014 Dec 15;564:254-61. doi: 10.1016/j.abb.2014.10.009. Epub 2014 Oct 25.

PMID:
25447819
27.

Effects of terminal dimethylation and metal coordination of proline-2-formylpyridine thiosemicarbazone hybrids on lipophilicity, antiproliferative activity, and hR2 RNR inhibition.

Bacher F, Dömötör O, Kaltenbrunner M, Mojović M, Popović-Bijelić A, Gräslund A, Ozarowski A, Filipovic L, Radulović S, Enyedy ÉA, Arion VB.

Inorg Chem. 2014 Dec 1;53(23):12595-609. doi: 10.1021/ic502239u. Epub 2014 Nov 12.

PMID:
25391085
28.

Alzheimer peptides aggregate into transient nanoglobules that nucleate fibrils.

Luo J, Wärmländer SK, Gräslund A, Abrahams JP.

Biochemistry. 2014 Oct 14;53(40):6302-8. doi: 10.1021/bi5003579. Epub 2014 Sep 29.

PMID:
25198136
29.

Electronic structural flexibility of heterobimetallic Mn/Fe cofactors: R2lox and R2c proteins.

Shafaat HS, Griese JJ, Pantazis DA, Roos K, Andersson CS, Popović-Bijelić A, Gräslund A, Siegbahn PE, Neese F, Lubitz W, Högbom M, Cox N.

J Am Chem Soc. 2014 Sep 24;136(38):13399-409. doi: 10.1021/ja507435t. Epub 2014 Sep 15.

PMID:
25153930
30.

Effects of cargo molecules on membrane perturbation caused by transportan10 based cell-penetrating peptides.

Vasconcelos L, Madani F, Arukuusk P, Pärnaste L, Gräslund A, Langel U.

Biochim Biophys Acta. 2014 Dec;1838(12):3118-29. doi: 10.1016/j.bbamem.2014.08.011. Epub 2014 Aug 15.

31.

Non-chaperone proteins can inhibit aggregation and cytotoxicity of Alzheimer amyloid β peptide.

Luo J, Wärmländer SK, Gräslund A, Abrahams JP.

J Biol Chem. 2014 Oct 3;289(40):27766-75. doi: 10.1074/jbc.M114.574947. Epub 2014 Aug 6.

32.

The Aβ peptide forms non-amyloid fibrils in the presence of carbon nanotubes.

Luo J, Wärmländer SK, Yu CH, Muhammad K, Gräslund A, Pieter Abrahams J.

Nanoscale. 2014 Jun 21;6(12):6720-6. doi: 10.1039/c4nr00291a.

PMID:
24820873
33.

Endogenous polyamines reduce the toxicity of soluble aβ peptide aggregates associated with Alzheimer's disease.

Luo J, Mohammed I, Wärmländer SK, Hiruma Y, Gräslund A, Abrahams JP.

Biomacromolecules. 2014 Jun 9;15(6):1985-91. doi: 10.1021/bm401874j. Epub 2014 May 2.

PMID:
24750033
34.

The hairpin conformation of the amyloid β peptide is an important structural motif along the aggregation pathway.

Abelein A, Abrahams JP, Danielsson J, Gräslund A, Jarvet J, Luo J, Tiiman A, Wärmländer SK.

J Biol Inorg Chem. 2014 Jun;19(4-5):623-34. doi: 10.1007/s00775-014-1131-8. Epub 2014 Apr 16. Review.

PMID:
24737040
35.

Direct detection of neuropeptide dynorphin A binding to the second extracellular loop of the κ opioid receptor using a soluble protein scaffold.

Björnerås J, Kurnik M, Oliveberg M, Gräslund A, Mäler L, Danielsson J.

FEBS J. 2014 Feb;281(3):814-24.

PMID:
24616919
36.

The class Ib ribonucleotide reductase from Mycobacterium tuberculosis has two active R2F subunits.

Hammerstad M, Røhr AK, Andersen NH, Gräslund A, Högbom M, Andersson KK.

J Biol Inorg Chem. 2014 Aug;19(6):893-902. doi: 10.1007/s00775-014-1121-x. Epub 2014 Mar 2.

PMID:
24585102
37.

The role of pro-inflammatory S100A9 in Alzheimer's disease amyloid-neuroinflammatory cascade.

Wang C, Klechikov AG, Gharibyan AL, Wärmländer SK, Jarvet J, Zhao L, Jia X, Narayana VK, Shankar SK, Olofsson A, Brännström T, Mu Y, Gräslund A, Morozova-Roche LA.

Acta Neuropathol. 2014 Apr;127(4):507-22. doi: 10.1007/s00401-013-1208-4. Epub 2013 Nov 16. Erratum in: Acta Neuropathol. 2014 Sep;128(3):461.

38.

Inhibiting and reversing amyloid-β peptide (1-40) fibril formation with gramicidin S and engineered analogues.

Luo J, Otero JM, Yu CH, Wärmländer SK, Gräslund A, Overhand M, Abrahams JP.

Chemistry. 2013 Dec 16;19(51):17338-48. doi: 10.1002/chem.201301535. Epub 2013 Nov 11.

PMID:
24218178
39.

Direct observation of structurally encoded metal discrimination and ether bond formation in a heterodinuclear metalloprotein.

Griese JJ, Roos K, Cox N, Shafaat HS, Branca RM, Lehtiö J, Gräslund A, Lubitz W, Siegbahn PE, Högbom M.

Proc Natl Acad Sci U S A. 2013 Oct 22;110(43):17189-94. doi: 10.1073/pnas.1304368110. Epub 2013 Oct 7.

40.

A highly cytotoxic modified paullone ligand bearing a TEMPO free-radical unit and its copper(II) complex as potential hR2 RNR inhibitors.

Dobrov A, Göschl S, Jakupec MA, Popović-Bijelić A, Gräslund A, Rapta P, Arion VB.

Chem Commun (Camb). 2013 Nov 4;49(85):10007-9. doi: 10.1039/c3cc45743e.

41.

Biophysical studies of the amyloid β-peptide: interactions with metal ions and small molecules.

Wärmländer S, Tiiman A, Abelein A, Luo J, Jarvet J, Söderberg KL, Danielsson J, Gräslund A.

Chembiochem. 2013 Sep 23;14(14):1692-704. doi: 10.1002/cbic.201300262. Epub 2013 Aug 26. Review.

PMID:
23983094
42.

Development of a novel nanoparticle by dual modification with the pluripotential cell-penetrating peptide PepFect6 for cellular uptake, endosomal escape, and decondensation of an siRNA core complex.

Mitsueda A, Shimatani Y, Ito M, Ohgita T, Yamada A, Hama S, Gräslund A, Lindberg S, Langel Ü, Harashima H, Nakase I, Futaki S, Kogure K.

Biopolymers. 2013 Nov;100(6):698-704. doi: 10.1002/bip.22310.

PMID:
23893316
43.

Formation of dynamic soluble surfactant-induced amyloid β peptide aggregation intermediates.

Abelein A, Kaspersen JD, Nielsen SB, Jensen GV, Christiansen G, Pedersen JS, Danielsson J, Otzen DE, Gräslund A.

J Biol Chem. 2013 Aug 9;288(32):23518-28. doi: 10.1074/jbc.M113.470450. Epub 2013 Jun 17.

44.

Human lysozyme inhibits the in vitro aggregation of Aβ peptides, which in vivo are associated with Alzheimer's disease.

Luo J, Wärmländer SK, Gräslund A, Abrahams JP.

Chem Commun (Camb). 2013 Jul 25;49(58):6507-9. doi: 10.1039/c3cc42325e. Epub 2013 Jun 13.

PMID:
23764522
45.

Membrane interaction of disease-related dynorphin A variants.

Björnerås J, Gräslund A, Mäler L.

Biochemistry. 2013 Jun 18;52(24):4157-67. doi: 10.1021/bi4004205. Epub 2013 Jun 10.

PMID:
23705820
46.

Cellular polyamines promote amyloid-beta (Aβ) peptide fibrillation and modulate the aggregation pathways.

Luo J, Yu CH, Yu H, Borstnar R, Kamerlin SC, Gräslund A, Abrahams JP, Wärmländer SK.

ACS Chem Neurosci. 2013 Mar 20;4(3):454-62. doi: 10.1021/cn300170x. Epub 2013 Jan 16.

47.

Rapid X-ray photoreduction of dimetal-oxygen cofactors in ribonucleotide reductase.

Sigfridsson KG, Chernev P, Leidel N, Popovic-Bijelic A, Gräslund A, Haumann M.

J Biol Chem. 2013 Apr 5;288(14):9648-61. doi: 10.1074/jbc.M112.438796. Epub 2013 Feb 11.

48.

In vitro and mechanistic studies of an antiamyloidogenic self-assembled cyclic D,L-α-peptide architecture.

Richman M, Wilk S, Chemerovski M, Wärmländer SK, Wahlström A, Gräslund A, Rahimipour S.

J Am Chem Soc. 2013 Mar 6;135(9):3474-84. doi: 10.1021/ja310064v. Epub 2013 Feb 19.

PMID:
23360549
49.

Engineered non-fluorescent Affibody molecules facilitate studies of the amyloid-beta (Aβ) peptide in monomeric form: low pH was found to reduce Aβ/Cu(II) binding affinity.

Lindgren J, Segerfeldt P, Sholts SB, Gräslund A, Karlström AE, Wärmländer SK.

J Inorg Biochem. 2013 Mar;120:18-23. doi: 10.1016/j.jinorgbio.2012.11.005. Epub 2012 Nov 30.

PMID:
23262458
50.

Modeling the endosomal escape of cell-penetrating peptides using a transmembrane pH gradient.

Madani F, Abdo R, Lindberg S, Hirose H, Futaki S, Langel U, Gräslund A.

Biochim Biophys Acta. 2013 Apr;1828(4):1198-204. doi: 10.1016/j.bbamem.2012.12.008. Epub 2012 Dec 19.

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