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Nuclear decoupling is part of a rapid protein-level cellular response to high-intensity mechanical loading.

Gilbert HTJ, Mallikarjun V, Dobre O, Jackson MR, Pedley R, Gilmore AP, Richardson SM, Swift J.

Nat Commun. 2019 Sep 12;10(1):4149. doi: 10.1038/s41467-019-11923-1.


Investigation of muscle transcriptomes using gradient boosting machine learning identifies molecular predictors of feed efficiency in growing pigs.

Messad F, Louveau I, Koffi B, Gilbert H, Gondret F.

BMC Genomics. 2019 Aug 17;20(1):659. doi: 10.1186/s12864-019-6010-9.


Magnetically Actuated Soft Capsule Endoscope for Fine-Needle Biopsy.

Son D, Gilbert H, Sitti M.

Soft Robot. 2019 Sep 12. doi: 10.1089/soro.2018.0171. [Epub ahead of print]


Genotype by environment interactions for performance and thermoregulation responses in growing pigs1,2.

Gourdine JL, Riquet J, Rosé R, Poullet N, Giorgi M, Billon Y, Renaudeau D, Gilbert H.

J Anim Sci. 2019 Sep 3;97(9):3699-3713. doi: 10.1093/jas/skz245.


Does quicker access to a senior decision maker make a difference in the acute medical unit?

Gilbert H, Lyne H, Visanji S, Hawksley A, Barker R.

Clin Med (Lond). 2019 Jun;19(Suppl 3):36. doi: 10.7861/clinmedicine.19-3-s36. No abstract available.


Effect of chronic and acute heat challenges on fecal microbiota composition, production, and thermoregulation traits in growing pigs1,2.

Le Sciellour M, Zemb O, Hochu I, Riquet J, Gilbert H, Giorgi M, Billon Y, Gourdine JL, Renaudeau D.

J Anim Sci. 2019 Sep 3;97(9):3845-3858. doi: 10.1093/jas/skz222.


An exploration of the barriers to attendance at the English Stop Smoking Services.

Kale D, Gilbert H, Sutton S.

Addict Behav Rep. 2018 Nov 1;9:005-5. doi: 10.1016/j.abrep.2018.10.005. eCollection 2019 Jun.


Dissecting total genetic variance into additive and dominance components of purebred and crossbred pig traits.

Tusell L, Gilbert H, Vitezica ZG, Mercat MJ, Legarra A, Larzul C.

Animal. 2019 May 23:1-11. doi: 10.1017/S1751731119001046. [Epub ahead of print]


Primary care management of cardiovascular risk for people with severe mental illnesses: the Primrose research programme including cluster RCT.

Osborn D, Burton A, Walters K, Atkins L, Barnes T, Blackburn R, Craig T, Gilbert H, Gray B, Hardoon S, Heinkel S, Holt R, Hunter R, Johnston C, King M, Leibowitz J, Marston L, Michie S, Morris R, Morris S, Nazareth I, Omar R, Petersen I, Peveler R, Pinfold V, Stevenson F, Zomer E.

Southampton (UK): NIHR Journals Library; 2019 Apr.


The consequences of ageing, progeroid syndromes and cellular senescence on mechanotransduction and the nucleus.

Gilbert HTJ, Swift J.

Exp Cell Res. 2019 May 1;378(1):98-103. doi: 10.1016/j.yexcr.2019.03.002. Epub 2019 Mar 2. Review.


Estimating direct genetic and maternal effects affecting rabbit growth and feed efficiency with a factorial design.

Garreau H, Ruesche J, Gilbert H, Balmisse E, Benitez F, Richard F, David I, Drouilhet L, Zemb O.

J Anim Breed Genet. 2019 May;136(3):168-173. doi: 10.1111/jbg.12380. Epub 2019 Jan 28.


Authors' response.

Greenhawt M, Marsh R, Gilbert H, Matlock D.

Ann Allergy Asthma Immunol. 2018 Nov;121(5):642-643. doi: 10.1016/j.anai.2018.08.020. No abstract available.


Genetic Parameters for Resistance to Non-specific Diseases and Production Traits Measured in Challenging and Selection Environments; Application to a Rabbit Case.

Gunia M, David I, Hurtaud J, Maupin M, Gilbert H, Garreau H.

Front Genet. 2018 Oct 16;9:467. doi: 10.3389/fgene.2018.00467. eCollection 2018.


Responses to weaning in two pig lines divergently selected for residual feed intake depending on diet.

Gilbert H, Ruesche J, Muller N, Billon Y, Begos V, Montagne L.

J Anim Sci. 2019 Jan 1;97(1):43-54. doi: 10.1093/jas/sky416.


A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation.

Cartmell A, Muñoz-Muñoz J, Briggs JA, Ndeh DA, Lowe EC, Baslé A, Terrapon N, Stott K, Heunis T, Gray J, Yu L, Dupree P, Fernandes PZ, Shah S, Williams SJ, Labourel A, Trost M, Henrissat B, Gilbert HJ.

Nat Microbiol. 2018 Nov;3(11):1314-1326. doi: 10.1038/s41564-018-0258-8. Epub 2018 Oct 22.


Structure and function of a glycoside hydrolase family 8 endoxylanase from Teredinibacter turnerae.

Fowler CA, Hemsworth GR, Cuskin F, Hart S, Turkenburg J, Gilbert HJ, Walton PH, Davies GJ.

Acta Crystallogr D Struct Biol. 2018 Oct 1;74(Pt 10):946-955. doi: 10.1107/S2059798318009737. Epub 2018 Oct 2.


Differential Effect of Recurrent Concussions on Symptom Clusters in Sport Concussion Assessment Tool.

Chen J, Oddson B, Gilbert HC.

J Sport Rehabil. 2019 Sep 1;28(7):735-739. doi: 10.1123/jsr.2018-0166.


Fecal microbial composition associated with variation in feed efficiency in pigs depends on diet and sex.

Verschuren LMG, Calus MPL, Jansman AJM, Bergsma R, Knol EF, Gilbert H, Zemb O.

J Anim Sci. 2018 Jul 28. doi: 10.1093/jas/sky268. [Epub ahead of print] No abstract available.


New susceptibility loci for cutaneous melanoma risk and progression revealed using a porcine model.

Bourneuf E, Estellé J, Blin A, Créchet F, Schneider MDP, Gilbert H, Brossard M, Vaysse A, Lathrop M, Vincent-Naulleau S, Demenais F.

Oncotarget. 2018 Jun 12;9(45):27682-27697. doi: 10.18632/oncotarget.25455. eCollection 2018 Jun 12.


Smokers' knowledge and perception of electronic cigarettes (e-cigarettes): a qualitative study of non-quitting smokers in a North London general practice.

Vasconcelos V, Gilbert H.

Prim Health Care Res Dev. 2018 Jul 2:1-9. doi: 10.1017/S1463423618000439. [Epub ahead of print]


Understanding caregiver goals, benefits, and acceptable risks of peanut allergy therapies.

Greenhawt M, Marsh R, Gilbert H, Sicherer S, DunnGalvin A, Matlock D.

Ann Allergy Asthma Immunol. 2018 Nov;121(5):575-579. doi: 10.1016/j.anai.2018.06.018. Epub 2018 Jun 27.


An immortalised mesenchymal stem cell line maintains mechano-responsive behaviour and can be used as a reporter of substrate stiffness.

Galarza Torre A, Shaw JE, Wood A, Gilbert HTJ, Dobre O, Genever P, Brennan K, Richardson SM, Swift J.

Sci Rep. 2018 Jun 12;8(1):8981. doi: 10.1038/s41598-018-27346-9.


Messaging Circumstances and Economic Pressures as Influences on Linkage to Medical Male Circumcision following Community-Based HIV Testing for Men in Rural Southwest Uganda: A Qualitative Study.

Gilbert HN, Wyatt MA, Asiimwe S, Turyamureeba B, Tumwesigye E, Van Rooyen H, Barnabas RV, Celum CL, Ware NC.

AIDS Res Treat. 2018 May 3;2018:8387436. doi: 10.1155/2018/8387436. eCollection 2018.


Higher order scaffoldin assembly in Ruminococcus flavefaciens cellulosome is coordinated by a discrete cohesin-dockerin interaction.

Bule P, Pires VMR, Alves VD, Carvalho AL, Prates JAM, Ferreira LMA, Smith SP, Gilbert HJ, Noach I, Bayer EA, Najmudin S, Fontes CMGA.

Sci Rep. 2018 May 3;8(1):6987. doi: 10.1038/s41598-018-25171-8.


Bacteroides thetaiotaomicron generates diverse α-mannosidase activities through subtle evolution of a distal substrate-binding motif.

Thompson AJ, Spears RJ, Zhu Y, Suits MDL, Williams SJ, Gilbert HJ, Davies GJ.

Acta Crystallogr D Struct Biol. 2018 May 1;74(Pt 5):394-404. doi: 10.1107/S2059798318002942. Epub 2018 Apr 24.


Fecal microbial composition associated with variation in feed efficiency in pigs depends on diet and sex.

Verschuren LMG, Calus MPL, Jansman AJM, Bergsma R, Knol EF, Gilbert H, Zemb O.

J Anim Sci. 2018 Apr 14;96(4):1405-1418. doi: 10.1093/jas/sky060. Erratum in: J Anim Sci. 2018 Jul 28;:.


Can Graphics Tell Lies? A Tutorial on How To Visualize Your Data.

Cabanski C, Gilbert H, Mosesova S.

Clin Transl Sci. 2018 Jul;11(4):371-377. doi: 10.1111/cts.12554. Epub 2018 Apr 26.


Precision oncology in advanced cancer patients improves overall survival with lower weekly healthcare costs.

Haslem DS, Chakravarty I, Fulde G, Gilbert H, Tudor BP, Lin K, Ford JM, Nadauld LD.

Oncotarget. 2018 Feb 2;9(15):12316-12322. doi: 10.18632/oncotarget.24384. eCollection 2018 Feb 23.


Degenerate intervertebral disc-like pH induces a catabolic mechanoresponse in human nucleus pulposus cells.

Hodson NW, Patel S, Richardson SM, Hoyland JA, Gilbert HTJ.

JOR Spine. 2018 Mar 11;1(1):e1004. doi: 10.1002/jsp2.1004. eCollection 2018 Mar.


Corrigendum: Complex pectin metabolism by gut bacteria reveals novel catalytic functions.

Ndeh D, Rogowski A, Cartmell A, Luis AS, Baslé A, Gray J, Venditto I, Briggs J, Zhang X, Labourel A, Terrapon N, Buffetto F, Nepogodiev S, Xiao Y, Field RA, Zhu Y, O'Neill MA, Urbanowicz BR, York WS, Davies GJ, Abbott DW, Ralet MC, Martens EC, Henrissat B, Gilbert HJ.

Nature. 2017 Aug 31;548(7669):612. doi: 10.1038/nature23659. Epub 2017 Aug 23.


Clinical and cost-effectiveness of an intervention for reducing cholesterol and cardiovascular risk for people with severe mental illness in English primary care: a cluster randomised controlled trial.

Osborn D, Burton A, Hunter R, Marston L, Atkins L, Barnes T, Blackburn R, Craig T, Gilbert H, Heinkel S, Holt R, King M, Michie S, Morris R, Morris S, Nazareth I, Omar R, Petersen I, Peveler R, Pinfold V, Walters K.

Lancet Psychiatry. 2018 Feb;5(2):145-154. doi: 10.1016/S2215-0366(18)30007-5. Epub 2018 Jan 22. Erratum in: Lancet Psychiatry. 2019 Jan;6(1):e2.


Structure-function analyses generate novel specificities to assemble the components of multienzyme bacterial cellulosome complexes.

Bule P, Cameron K, Prates JAM, Ferreira LMA, Smith SP, Gilbert HJ, Bayer EA, Najmudin S, Fontes CMGA, Alves VD.

J Biol Chem. 2018 Mar 16;293(11):4201-4212. doi: 10.1074/jbc.RA117.001241. Epub 2018 Jan 24.


Biochemistry of complex glycan depolymerisation by the human gut microbiota.

Ndeh D, Gilbert HJ.

FEMS Microbiol Rev. 2018 Mar 1;42(2):146-164. doi: 10.1093/femsre/fuy002. Review.


CD8+ T cell infiltration in breast and colon cancer: A histologic and statistical analysis.

Ziai J, Gilbert HN, Foreman O, Eastham-Anderson J, Chu F, Huseni M, Kim JM.

PLoS One. 2018 Jan 10;13(1):e0190158. doi: 10.1371/journal.pone.0190158. eCollection 2018.


Interactions between sire family and production environment (temperate vs. tropical) on performance and thermoregulation responses in growing pigs.

Rosé R, Gilbert H, Loyau T, Giorgi M, Billon Y, Riquet J, Renaudeau D, Gourdine JL.

J Anim Sci. 2017 Nov;95(11):4738-4751. doi: 10.2527/jas2017.1611.


Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides.

Luis AS, Briggs J, Zhang X, Farnell B, Ndeh D, Labourel A, Baslé A, Cartmell A, Terrapon N, Stott K, Lowe EC, McLean R, Shearer K, Schückel J, Venditto I, Ralet MC, Henrissat B, Martens EC, Mosimann SC, Abbott DW, Gilbert HJ.

Nat Microbiol. 2018 Feb;3(2):210-219. doi: 10.1038/s41564-017-0079-1. Epub 2017 Dec 18.


Expression system for structural and functional studies of human glycosylation enzymes.

Moremen KW, Ramiah A, Stuart M, Steel J, Meng L, Forouhar F, Moniz HA, Gahlay G, Gao Z, Chapla D, Wang S, Yang JY, Prabhakar PK, Johnson R, Rosa MD, Geisler C, Nairn AV, Seetharaman J, Wu SC, Tong L, Gilbert HJ, LaBaer J, Jarvis DL.

Nat Chem Biol. 2018 Feb;14(2):156-162. doi: 10.1038/nchembio.2539. Epub 2017 Dec 18.


1HNMR-Based metabolomic profiling method to develop plasma biomarkers for sensitivity to chronic heat stress in growing pigs.

Dou S, Villa-Vialaneix N, Liaubet L, Billon Y, Giorgi M, Gilbert H, Gourdine JL, Riquet J, Renaudeau D.

PLoS One. 2017 Nov 27;12(11):e0188469. doi: 10.1371/journal.pone.0188469. eCollection 2017.


Cost-effectiveness of personal tailored risk information and taster sessions to increase the uptake of the NHS stop smoking services: the Start2quit randomized controlled trial.

Wu Q, Gilbert H, Nazareth I, Sutton S, Morris R, Petersen I, Galton S, Parrott S.

Addiction. 2018 Apr;113(4):708-718. doi: 10.1111/add.14086. Epub 2017 Dec 11.


PULDB: the expanded database of Polysaccharide Utilization Loci.

Terrapon N, Lombard V, Drula É, Lapébie P, Al-Masaudi S, Gilbert HJ, Henrissat B.

Nucleic Acids Res. 2018 Jan 4;46(D1):D677-D683. doi: 10.1093/nar/gkx1022.


Target highlights from the first post-PSI CASP experiment (CASP12, May-August 2016).

Kryshtafovych A, Albrecht R, Baslé A, Bule P, Caputo AT, Carvalho AL, Chao KL, Diskin R, Fidelis K, Fontes CMGA, Fredslund F, Gilbert HJ, Goulding CW, Hartmann MD, Hayes CS, Herzberg O, Hill JC, Joachimiak A, Kohring GW, Koning RI, Lo Leggio L, Mangiagalli M, Michalska K, Moult J, Najmudin S, Nardini M, Nardone V, Ndeh D, Nguyen TH, Pintacuda G, Postel S, van Raaij MJ, Roversi P, Shimon A, Singh AK, Sundberg EJ, Tars K, Zitzmann N, Schwede T.

Proteins. 2018 Mar;86 Suppl 1:27-50. doi: 10.1002/prot.25392. Epub 2017 Oct 16.


Impact of hygiene of housing conditions on performance and health of two pig genetic lines divergent for residual feed intake.

Chatelet A, Gondret F, Merlot E, Gilbert H, Friggens NC, Le Floc'h N.

Animal. 2018 Feb;12(2):350-358. doi: 10.1017/S1751731117001379. Epub 2017 Jun 27.


An evolutionarily distinct family of polysaccharide lyases removes rhamnose capping of complex arabinogalactan proteins.

Munoz-Munoz J, Cartmell A, Terrapon N, Baslé A, Henrissat B, Gilbert HJ.

J Biol Chem. 2017 Aug 11;292(32):13271-13283. doi: 10.1074/jbc.M117.794578. Epub 2017 Jun 21.


How members of the human gut microbiota overcome the sulfation problem posed by glycosaminoglycans.

Cartmell A, Lowe EC, Baslé A, Firbank SJ, Ndeh DA, Murray H, Terrapon N, Lombard V, Henrissat B, Turnbull JE, Czjzek M, Gilbert HJ, Bolam DN.

Proc Natl Acad Sci U S A. 2017 Jul 3;114(27):7037-7042. doi: 10.1073/pnas.1704367114. Epub 2017 Jun 19.


Optimization of Curvilinear Needle Trajectories for Transforamenal Hippocampotomy.

Comber DB, Pitt EB, Gilbert HB, Powelson MW, Matijevich E, Neimat JS, Webster RJ 3rd, Barth EJ.

Oper Neurosurg (Hagerstown). 2017 Feb;13(1):15-22. doi: 10.1227/NEU.0000000000001361. Epub 2016 Jul 25.


A Bacteroidetes locus dedicated to fungal 1,6-β-glucan degradation: Unique substrate conformation drives specificity of the key endo-1,6-β-glucanase.

Temple MJ, Cuskin F, Baslé A, Hickey N, Speciale G, Williams SJ, Gilbert HJ, Lowe EC.

J Biol Chem. 2017 Jun 23;292(25):10639-10650. doi: 10.1074/jbc.M117.787606. Epub 2017 May 1.


Unusual active site location and catalytic apparatus in a glycoside hydrolase family.

Munoz-Munoz J, Cartmell A, Terrapon N, Henrissat B, Gilbert HJ.

Proc Natl Acad Sci U S A. 2017 May 9;114(19):4936-4941. doi: 10.1073/pnas.1701130114. Epub 2017 Apr 10.


Assembly of Ruminococcus flavefaciens cellulosome revealed by structures of two cohesin-dockerin complexes.

Bule P, Alves VD, Israeli-Ruimy V, Carvalho AL, Ferreira LMA, Smith SP, Gilbert HJ, Najmudin S, Bayer EA, Fontes CMGA.

Sci Rep. 2017 Apr 7;7(1):759. doi: 10.1038/s41598-017-00919-w.


Direct and correlated responses to selection in two lines of rabbits selected for feed efficiency under ad libitum and restricted feeding: III. Digestion and excretion of nitrogen and minerals.

Gidenne T, Fortun-Lamothe L, Bannelier C, Molette C, Gilbert H, Chemit ML, Segura M, Benitez F, Richard F, Garreau H, Drouilhet L.

J Anim Sci. 2017 Mar;95(3):1301-1312. doi: 10.2527/jas.2016.1192.


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