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Items: 42


Inhibition of IL-23 mediated inflammation with a novel small molecule inverse agonist of RORgt.

Gauld S, Jacquet S, Gauvin D, Wallace C, Wang Y, McCarthy R, Goess C, Leys L, Huang S, Su Z, Edelmayer R, Wetter J, Salte K, McGaraughty S, Argiriadi M, Honore P, Luccarini JM, Bressac D, Desino K, Breinlinger E, Cusack K, Potin D, Kort M, Masson P.

J Pharmacol Exp Ther. 2019 Aug 2. pii: jpet.119.258046. doi: 10.1124/jpet.119.258046. [Epub ahead of print]


Discovery of novel quinoline sulphonamide derivatives as potent, selective and orally active RORĪ³ inverse agonists.

Amaudrut J, Argiriadi MA, Barth M, Breinlinger EC, Bressac D, Broqua P, Calderwood DJ, Chatar M, Cusack KP, Gauld SB, Jacquet S, Kamath RV, Kort ME, Lepais V, Luccarini JM, Masson P, Montalbetti C, Mounier L, Potin D, Poupardin O, Rouaud S, Spitzer L, Wallace CD.

Bioorg Med Chem Lett. 2019 Jul 15;29(14):1799-1806. doi: 10.1016/j.bmcl.2019.05.015. Epub 2019 May 9.


Monocytes/Macrophages play a pathogenic role in IL-23 mediated psoriasis-like skin inflammation.

Wang Y, Edelmayer R, Wetter J, Salte K, Gauvin D, Leys L, Paulsboe S, Su Z, Weinberg I, Namovic M, Gauld SB, Honore P, Scott VE, McGaraughty S.

Sci Rep. 2019 Mar 29;9(1):5310. doi: 10.1038/s41598-019-41655-7.


Mechanistic and pharmacological assessment of murine IL-23 mediated psoriasiform dermatitis; implications for drug discovery.

Gauld SB, Gauvin D, Olson L, Leys L, Paulsboe S, Liu Z, Edelmayer RM, Wetter J, Salte K, Wang Y, Huang S, Honore P, McGaraughty S.

J Dermatol Sci. 2018 Oct;92(1):45-53. doi: 10.1016/j.jdermsci.2018.08.001. Epub 2018 Aug 7.


B Cell-Specific Expression of Ataxia-Telangiectasia Mutated Protein Kinase Promotes Chronic Gammaherpesvirus Infection.

Darrah EJ, Kulinski JM, Mboko WP, Xin G, Malherbe LP, Gauld SB, Cui W, Tarakanova VL.

J Virol. 2017 Sep 12;91(19). pii: e01103-17. doi: 10.1128/JVI.01103-17. Print 2017 Oct 1.


The Use of Salmonella Typhim Vaccine to Diagnose Antibody Deficiency.

Bausch-Jurken MT, Verbsky JW, Gonzaga KA, Elms NP, Hintermeyer MK, Gauld SB, Routes JM.

J Clin Immunol. 2017 Jul;37(5):427-433. doi: 10.1007/s10875-017-0406-6. Epub 2017 Jun 7.


Tumor Suppressor Interferon-Regulatory Factor 1 Counteracts the Germinal Center Reaction Driven by a Cancer-Associated Gammaherpesvirus.

Mboko WP, Olteanu H, Ray A, Xin G, Darrah EJ, Kumar SN, Kulinski JM, Cui W, Dittel BN, Gauld SB, Tarakanova VL.

J Virol. 2015 Dec 30;90(6):2818-29. doi: 10.1128/JVI.02774-15.


ATM facilitates mouse gammaherpesvirus reactivation from myeloid cells during chronic infection.

Kulinski JM, Darrah EJ, Broniowska KA, Mboko WP, Mounce BC, Malherbe LP, Corbett JA, Gauld SB, Tarakanova VL.

Virology. 2015 Sep;483:264-74. doi: 10.1016/j.virol.2015.04.026. Epub 2015 May 21.


Modulation of B-cell tolerance by murine gammaherpesvirus 68 infection: requirement for Orf73 viral gene expression and follicular helper T cells.

Gauld SB, De Santis JL, Kulinski JM, McGraw JA, Leonardo SM, Ruder EA, Maier W, Tarakanova VL.

Immunology. 2013 Jun;139(2):197-204. doi: 10.1111/imm.12069.


Ataxia telangiectasia mutated kinase controls chronic gammaherpesvirus infection.

Kulinski JM, Leonardo SM, Mounce BC, Malherbe L, Gauld SB, Tarakanova VL.

J Virol. 2012 Dec;86(23):12826-37. doi: 10.1128/JVI.00917-12. Epub 2012 Sep 19.


Comparison of methods to control floor contamination in an animal research facility.

Allen KP, Csida T, Leming J, Murray K, Gauld SB, Thulin J.

Lab Anim (NY). 2012 Oct;41(10):282-8. doi: 10.1038/laban1012-282.


Expansion of follicular helper T cells in the absence of Treg cells: implications for loss of B-cell anergy.

Leonardo SM, De Santis JL, Gehrand A, Malherbe LP, Gauld SB.

Eur J Immunol. 2012 Oct;42(10):2597-607. doi: 10.1002/eji.201242616. Epub 2012 Aug 6.


Autoreactive preplasma cells break tolerance in the absence of regulation by dendritic cells and macrophages.

Gilbert MR, Wagner NJ, Jones SZ, Wisz AB, Roques JR, Krum KN, Lee SR, Nickeleit V, Hulbert C, Thomas JW, Gauld SB, Vilen BJ.

J Immunol. 2012 Jul 15;189(2):711-20. doi: 10.4049/jimmunol.1102973. Epub 2012 Jun 6.


Requirements for growth and IL-10 expression of highly purified human T regulatory cells.

Bonacci B, Edwards B, Jia S, Williams CB, Hessner MJ, Gauld SB, Verbsky JW.

J Clin Immunol. 2012 Oct;32(5):1118-28. doi: 10.1007/s10875-012-9701-4. Epub 2012 May 5.


Cutting edge: in the absence of regulatory T cells, a unique Th cell population expands and leads to a loss of B cell anergy.

Leonardo SM, De Santis JL, Malherbe LP, Gauld SB.

J Immunol. 2012 Jun 1;188(11):5223-6. doi: 10.4049/jimmunol.1103731. Epub 2012 Apr 27.


Monophosphorylation of CD79a and CD79b ITAM motifs initiates a SHIP-1 phosphatase-mediated inhibitory signaling cascade required for B cell anergy.

O'Neill SK, Getahun A, Gauld SB, Merrell KT, Tamir I, Smith MJ, Dal Porto JM, Li QZ, Cambier JC.

Immunity. 2011 Nov 23;35(5):746-56. doi: 10.1016/j.immuni.2011.10.011. Epub 2011 Nov 9.


Using participatory action research in community-based rehabilitation for people with acquired brain injury: from service provision to partnership with Aboriginal communities.

Gauld S, Smith S, Kendall MB.

Disabil Rehabil. 2011;33(19-20):1901-11. doi: 10.3109/09638288.2010.550382. Epub 2011 Jan 25.


CD23-mediated cell signaling in human B cells differs from signaling in cells of the monocytic lineage.

Chan MA, Gigliotti NM, Matangkasombut P, Gauld SB, Cambier JC, Rosenwasser LJ.

Clin Immunol. 2010 Dec;137(3):330-6. doi: 10.1016/j.clim.2010.08.005.


Altered B cell development and anergy in the absence of Foxp3.

Leonardo SM, Josephson JA, Hartog NL, Gauld SB.

J Immunol. 2010 Aug 15;185(4):2147-56. doi: 10.4049/jimmunol.1000136. Epub 2010 Jul 16.


Conserved gammaherpesvirus kinase and histone variant H2AX facilitate gammaherpesvirus latency in vivo.

Tarakanova VL, Stanitsa E, Leonardo SM, Bigley TM, Gauld SB.

Virology. 2010 Sep 15;405(1):50-61. doi: 10.1016/j.virol.2010.05.027. Epub 2010 Jun 16.


Fluorescence-based assays as tools for understanding immunologic processes.

Leonardo SM, Harnett MM, Lerch-Gaggl AF, Gauld SB.

Ann Allergy Asthma Immunol. 2009 Jan;102(1):84-90. doi: 10.1016/S1081-1206(10)60113-5. No abstract available.


B-cell anergy: from transgenic models to naturally occurring anergic B cells?

Cambier JC, Gauld SB, Merrell KT, Vilen BJ.

Nat Rev Immunol. 2007 Aug;7(8):633-43. Epub 2007 Jul 20. Review.


Ig allotypic inclusion does not prevent B cell development or response.

Velez MG, Kane M, Liu S, Gauld SB, Cambier JC, Torres RM, Pelanda R.

J Immunol. 2007 Jul 15;179(2):1049-57.


Identification of anergic B cells within a wild-type repertoire.

Merrell KT, Benschop RJ, Gauld SB, Aviszus K, Decote-Ricardo D, Wysocki LJ, Cambier JC.

Immunity. 2006 Dec;25(6):953-62.


Silencing of autoreactive B cells by anergy: a fresh perspective.

Gauld SB, Merrell KT, Cambier JC.

Curr Opin Immunol. 2006 Jun;18(3):292-7. Epub 2006 Apr 17. Review.


Maintenance of B cell anergy requires constant antigen receptor occupancy and signaling.

Gauld SB, Benschop RJ, Merrell KT, Cambier JC.

Nat Immunol. 2005 Nov;6(11):1160-7. Epub 2005 Oct 2.


Src-family kinases in B-cell development and signaling.

Gauld SB, Cambier JC.

Oncogene. 2004 Oct 18;23(48):8001-6. Review.


B cell antigen receptor signaling 101.

Dal Porto JM, Gauld SB, Merrell KT, Mills D, Pugh-Bernard AE, Cambier J.

Mol Immunol. 2004 Jul;41(6-7):599-613. Review.


Bcl-(xL) antagonism of BCR-coupled mitochondrial phospholipase A(2) signaling correlates with protection from apoptosis in WEHI-231 B cells.

Katz E, Lord C, Ford CA, Gauld SB, Carter NA, Harnett MM.

Blood. 2004 Jan 1;103(1):168-76. Epub 2003 Sep 11.


Paranasal sinus anatomy of Aegyptopithecus: implications for hominoid origins.

Rossie JB, Simons EL, Gauld SC, Rasmussen DT.

Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):8454-6.


B cell antigen receptor signaling: roles in cell development and disease.

Gauld SB, Dal Porto JM, Cambier JC.

Science. 2002 May 31;296(5573):1641-2. Review.


Selective down-regulation of the G(q)alpha/G11alpha G-protein family in tumour necrosis factor-alpha induced cell death.

Pollock VP, Lofthouse EJ, Jupp OJ, Gauld SB, Anderson HM, MacEwan DJ.

Mol Cell Biochem. 2000 Mar;206(1-2):67-74.


Allometric patterns of cranial bone thickness in fossil hominids.

Gauld SC.

Am J Phys Anthropol. 1996 Jul;100(3):411-26.


Medical evacuations from offshore structures.

Norman JN, Ballantine BN, Brebner JA, Brown B, Gauld SJ, Mawdsley J, Roythorne C, Valentine MJ, Wilcock SE.

Br J Ind Med. 1988 Sep;45(9):619-23.


Respiratory ill health among coal miners and telecommunication workers in south Wales.

Lloyd MH, Gauld SJ, Soutar CA.

Br J Ind Med. 1986 Mar;43(3):177-81.


Epidemiologic study of back pain in miners and office workers.

Lloyd MH, Gauld S, Soutar CA.

Spine (Phila Pa 1976). 1986 Mar;11(2):136-40.


Epidemiological study of the lung function of workers at a factory manufacturing polyvinylchloride.

Lloyd MH, Gauld S, Copland L, Soutar CA.

Br J Ind Med. 1984 Aug;41(3):328-33.


Emphysema and dust exposure in a group of coal workers.

Ruckley VA, Gauld SJ, Chapman JS, Davis JM, Douglas AN, Fernie JM, Jacobsen M, Lamb D.

Am Rev Respir Dis. 1984 Apr;129(4):528-32.


Clinical studies of workers exposed to polyvinylchloride dust.

Soutar CA, Gauld S.

Thorax. 1983 Nov;38(11):834-9.


Histocompatibility antigens in coal miners with pneumoconiosis.

Soutar CA, Coutts I, Parkes WR, Dodi IA, Gauld S, Castro JE, Turner-Warwick M.

Br J Ind Med. 1983 Feb;40(1):34-8.

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