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Items: 1 to 50 of 541

1.

Ambidextrous Approach To Disrupt Redox Balance in Tumor Cells with Increased ROS Production and Decreased GSH Synthesis for Cancer Therapy.

Kou L, Sun R, Xiao S, Zheng Y, Chen Z, Cai A, Zheng H, Yao Q, Ganapathy V, Chen R.

ACS Appl Mater Interfaces. 2019 Jul 31;11(30):26722-26730. doi: 10.1021/acsami.9b09784. Epub 2019 Jul 18.

PMID:
31276364
2.

Renal Iron Accelerates the Progression of Diabetic Nephropathy in HFE (High Fe-iron) Gene Knockout Mouse Model of Iron Overload.

Chaudhary K, Chilakala A, Ananth S, Mandala A, Veeranan-Karmegam R, Powell FL, Ganapathy V, Gnana-Prakasam JP.

Am J Physiol Renal Physiol. 2019 Jun 12. doi: 10.1152/ajprenal.00184.2019. [Epub ahead of print]

PMID:
31188032
3.

Evaluation of leptin concentration in Gingival Crevicular Fluid (GCF) during orthodontic tooth movement and its correlation to the rate of tooth movement.

Srinivasan B, Chitharanjan A, Kailasam V, Lavu V, Ganapathy V.

J Orthod Sci. 2019 May 23;8:6. doi: 10.4103/jos.JOS_58_18. eCollection 2019.

4.

Correction to: Rescue of Methyl-CpG Binding Protein 2 Dysfunction-induced Defects in Newborn Neurons by Pentobarbital.

Ma D, Yoon SI, Yang CH, Marcy G, Zhao N, Leong WY, Ganapathy V, Han J, Van Dongen AMJ, Hsu KS, Ming GL, Augustine GJ, Goh ELK.

Neurotherapeutics. 2019 Apr 30. doi: 10.1007/s13311-019-00738-z. [Epub ahead of print]

PMID:
31041779
5.

Development and radiosynthesis of the first 18 F-labeled inhibitor of monocarboxylate transporters (MCTs).

Sadeghzadeh M, Moldovan RP, Fischer S, Wenzel B, Ludwig FA, Teodoro R, Deuther-Conrad W, Jonnalagadda S, Jonnalagadda SK, Gudelis E, Šačkus A, Higuchi K, Ganapathy V, Mereddy VR, Drewes LR, Brust P.

J Labelled Comp Radiopharm. 2019 Jun 30;62(8):411-424. doi: 10.1002/jlcr.3739.

PMID:
31017677
6.

Adjacent-segment disease following two-level axial lumbar interbody fusion.

Michael AP, Weber MW, Delfino KR, Ganapathy V.

J Neurosurg Spine. 2019 Apr 19:1-8. doi: 10.3171/2019.2.SPINE18929. [Epub ahead of print]

PMID:
31003221
7.

Transport Mechanisms for the Nutritional Supplement β-Hydroxy-β-Methylbutyrate (HMB) in Mammalian Cells.

Ogura J, Sato T, Higuchi K, Bhutia YD, Babu E, Masuda M, Miyauchi S, Rueda R, Pereira SL, Ganapathy V.

Pharm Res. 2019 Apr 17;36(6):84. doi: 10.1007/s11095-019-2626-3.

PMID:
30997560
8.

Rationale and Study Design of a Randomized Clinical Trial of Metformin to Prevent Frailty in Older Adults with Pre-Diabetes.

Espinoza SE, Musi N, Wang CP, Michalek J, Orsak B, Romo T, Powers B, Conde A, Moris M, Bair-Kelps D, Li Y, Ganapathy V, Jergensen TE, Kelly LC, Jiwani R.

J Gerontol A Biol Sci Med Sci. 2019 Mar 19. pii: glz078. doi: 10.1093/gerona/glz078. [Epub ahead of print]

PMID:
30888034
9.

Primary Vesical Amyloidosis Masquerading as Vesical Calculus in a Retroviral Positive Patient.

Ganapathy V, Vijayakumar C, Karthikeyan VS, Srinivas J, Shrinuvasan S.

Cureus. 2019 Jan 4;11(1):e3828. doi: 10.7759/cureus.3828.

10.

Health-Related Quality of Life Improvements in Moderate to Very Severe Chronic Obstructive Pulmonary Disease Patients on Nebulized Glycopyrrolate: Evidence from the GOLDEN Studies.

Ferguson GT, Kerwin EM, Donohue JF, Ganapathy V, Tosiello RL, Bollu VK, Rajagopalan K.

Chronic Obstr Pulm Dis. 2018 Jun 6;5(3):193-207. doi: 10.15326/jcopdf.5.3.2017.0178.

11.

Transport of 2,4-dichloro phenoxyacetic acid by human Na+-coupled monocarboxylate transporter 1 (hSMCT1, SLC5A8).

Sugio K, Inoda D, Masuda M, Azumaya I, Sasaki S, Shimono K, Ganapathy V, Miyauchi S.

Drug Metab Pharmacokinet. 2019 Feb;34(1):95-103. doi: 10.1016/j.dmpk.2018.10.004. Epub 2018 Nov 8.

PMID:
30583944
12.

Satisfaction with the Use of eFlow Closed-System Nebulizer in Patients with Moderate-to-Very Severe Chronic Obstructive Pulmonary Disease: Findings from a Long-Term Safety Study.

Kerwin EM, Donohue JF, Ferguson GT, Ganapathy V, Ozol-Godfrey A, Rajagopalan K.

J Aerosol Med Pulm Drug Deliv. 2019 Feb;32(1):24-33. doi: 10.1089/jamp.2018.1477. Epub 2018 Nov 17.

PMID:
30457433
13.

Surface-Modified Shortwave-Infrared-Emitting Nanophotonic Reporters for Gene-Therapy Applications.

Zhao Z, Kantamneni H, He S, Pelka S, Venkataraman AS, Kwon M, Libutti SK, Pierce M, Moghe PV, Ganapathy V, Tan MC.

ACS Biomater Sci Eng. 2018 Jul 9;4(7):2305-2363. doi: 10.1021/acsbiomaterials.8b00378. Epub 2018 Apr 30.

14.

Embryonic lethality in mice due to carnitine transporter OCTN2 defect and placental carnitine deficiency.

Shekhawat PS, Sonne S, Matern D, Ganapathy V.

Placenta. 2018 Sep;69:71-73. doi: 10.1016/j.placenta.2018.06.312. Epub 2018 Jun 30.

PMID:
30213487
15.

Antibiotic use in patients hospitalized with chronic obstructive pulmonary disease.

Dietrich E, Davis K, Amin AN, Ganapathy V, Netzer L.

Am J Health Syst Pharm. 2018 Sep 1;75(17):1268-1269. doi: 10.2146/ajhp180178. No abstract available.

PMID:
30139734
16.

Chemical validation and optimization of pharmacoperones targeting vasopressin type 2 receptor mutant.

Janovick JA, Spicer TP, Bannister TD, Smith E, Ganapathy V, Scampavia L.

Biochem J. 2018 Sep 25;475(18):2941-2953. doi: 10.1042/BCJ20180065.

PMID:
30068530
17.

Retraction Note: Identification of a novel Na+-coupled Fe3+-citrate transport system, distinct from mammalian INDY, for uptake of citrate in mammalian cells.

Ogura J, Babu E, Miyauchi S, Ramachandran S, Nemeth E, Bhutia YD, Ganapathy V.

Sci Rep. 2018 Jul 17;8(1):11021. doi: 10.1038/s41598-018-28645-x.

18.

Recent advances in drug delivery via the organic cation/carnitine transporter 2 (OCTN2/SLC22A5).

Kou L, Sun R, Ganapathy V, Yao Q, Chen R.

Expert Opin Ther Targets. 2018 Aug;22(8):715-726. doi: 10.1080/14728222.2018.1502273. Epub 2018 Jul 23. Review.

PMID:
30016594
19.

Preparation of self-assembled platinum nanoclusters to combat Salmonella typhi infection and inhibit biofilm formation.

Subramaniyan SB, Ramani A, Ganapathy V, Anbazhagan V.

Colloids Surf B Biointerfaces. 2018 Nov 1;171:75-84. doi: 10.1016/j.colsurfb.2018.07.023. Epub 2018 Jul 11.

PMID:
30015141
20.

Fronto-striatal effective connectivity of working memory in adults with cannabis use disorder.

Ma L, Steinberg JL, Bjork JM, Keyser-Marcus L, Vassileva J, Zhu M, Ganapathy V, Wang Q, Boone EL, Ferré S, Bickel WK, Gerard Moeller F.

Psychiatry Res Neuroimaging. 2018 Aug 30;278:21-34. doi: 10.1016/j.pscychresns.2018.05.010. Epub 2018 Jun 8.

PMID:
29957349
21.

Electronic cigarette aerosols induce DNA damage and reduce DNA repair: Consistency across species.

Queimado L, Wagener T, Ganapathy V.

Proc Natl Acad Sci U S A. 2018 Jun 12;115(24):E5437-E5438. doi: 10.1073/pnas.1807411115. Epub 2018 May 25. No abstract available.

22.

Multiscale optical imaging of rare-earth-doped nanocomposites in a small animal model.

Higgins LM, Ganapathy V, Kantamneni H, Zhao X, Sheng Y, Tan MC, Roth CM, Riman RE, Moghe PV, Pierce MC.

J Biomed Opt. 2018 Mar;23(3):1-4. doi: 10.1117/1.JBO.23.3.030505.

23.

Treatment patterns for patients hospitalized with chronic obstructive pulmonary disease.

Amin AN, Bollu V, Stensland MD, Netzer L, Ganapathy V.

Am J Health Syst Pharm. 2018 Mar 15;75(6):359-366. doi: 10.2146/ajhp160979.

PMID:
29523532
24.

Gpr109a Limits Microbiota-Induced IL-23 Production To Constrain ILC3-Mediated Colonic Inflammation.

Bhatt B, Zeng P, Zhu H, Sivaprakasam S, Li S, Xiao H, Dong L, Shiao P, Kolhe R, Patel N, Li H, Levy-Bercowski D, Ganapathy V, Singh N.

J Immunol. 2018 Apr 15;200(8):2905-2914. doi: 10.4049/jimmunol.1701625. Epub 2018 Mar 7.

25.

Extracellular Citrate Affects Critical Elements of Cancer Cell Metabolism and Supports Cancer Development In Vivo.

Mycielska ME, Dettmer K, Rümmele P, Schmidt K, Prehn C, Milenkovic VM, Jagla W, Madej GM, Lantow M, Schladt M, Cecil A, Koehl GE, Eggenhofer E, Wachsmuth CJ, Ganapathy V, Schlitt HJ, Kunzelmann K, Ziegler C, Wetzel CH, Gaumann A, Lang SA, Adamski J, Oefner PJ, Geissler EK.

Cancer Res. 2018 May 15;78(10):2513-2523. doi: 10.1158/0008-5472.CAN-17-2959. Epub 2018 Mar 6.

26.

Vesicle-based secretion in schistosomes: Analysis of protein and microRNA (miRNA) content of exosome-like vesicles derived from Schistosoma mansoni.

Samoil V, Dagenais M, Ganapathy V, Aldridge J, Glebov A, Jardim A, Ribeiro P.

Sci Rep. 2018 Feb 19;8(1):3286. doi: 10.1038/s41598-018-21587-4.

27.

Iron Overload Accelerates the Progression of Diabetic Retinopathy in Association with Increased Retinal Renin Expression.

Chaudhary K, Promsote W, Ananth S, Veeranan-Karmegam R, Tawfik A, Arjunan P, Martin P, Smith SB, Thangaraju M, Kisselev O, Ganapathy V, Gnana-Prakasam JP.

Sci Rep. 2018 Feb 14;8(1):3025. doi: 10.1038/s41598-018-21276-2.

28.

Transporter-Guided Delivery of Nanoparticles to Improve Drug Permeation across Cellular Barriers and Drug Exposure to Selective Cell Types.

Kou L, Bhutia YD, Yao Q, He Z, Sun J, Ganapathy V.

Front Pharmacol. 2018 Jan 26;9:27. doi: 10.3389/fphar.2018.00027. eCollection 2018. Review.

29.

Identification of a novel Na+-coupled Fe3+-citrate transport system, distinct from mammalian INDY, for uptake of citrate in mammalian cells.

Ogura J, Babu E, Miyauchi S, Ramachandran S, Nemeth E, Bhutia YD, Ganapathy V.

Sci Rep. 2018 Feb 6;8(1):2519. doi: 10.1038/s41598-018-20620-w. Retraction in: Sci Rep. 2018 Jul 17;8(1):11021.

30.

GPR81, a Cell-Surface Receptor for Lactate, Regulates Intestinal Homeostasis and Protects Mice from Experimental Colitis.

Ranganathan P, Shanmugam A, Swafford D, Suryawanshi A, Bhattacharjee P, Hussein MS, Koni PA, Prasad PD, Kurago ZB, Thangaraju M, Ganapathy V, Manicassamy S.

J Immunol. 2018 Mar 1;200(5):1781-1789. doi: 10.4049/jimmunol.1700604. Epub 2018 Jan 31.

31.

Short-Chain Fatty Acid Transporters: Role in Colonic Homeostasis.

Sivaprakasam S, Bhutia YD, Yang S, Ganapathy V.

Compr Physiol. 2017 Dec 12;8(1):299-314. doi: 10.1002/cphy.c170014. Review.

32.

Delay in State Adoption of Newborn Screening Tests.

Xu A, Ganapathy V, Morain SR.

Pediatrics. 2018 Jan;141(1). pii: e20170300. doi: 10.1542/peds.2017-0300. Epub 2017 Dec 20. No abstract available. Erratum in: Pediatrics. 2018 Mar 30;:.

33.

The Na+/Cl--Coupled, Broad-Specific, Amino Acid Transporter SLC6A14 (ATB0,+): Emerging Roles in Multiple Diseases and Therapeutic Potential for Treatment and Diagnosis.

Sikder MOF, Yang S, Ganapathy V, Bhutia YD.

AAPS J. 2017 Dec 4;20(1):12. doi: 10.1208/s12248-017-0164-7. Review.

PMID:
29204754
34.

Role of estrogen receptor beta in neural differentiation of mouse embryonic stem cells.

Varshney MK, Inzunza J, Lupu D, Ganapathy V, Antonson P, Rüegg J, Nalvarte I, Gustafsson JÅ.

Proc Natl Acad Sci U S A. 2017 Nov 28;114(48):E10428-E10437. doi: 10.1073/pnas.1714094114. Epub 2017 Nov 13.

35.

Effective Floquet Hamiltonian theory of multiple-quantum NMR in anisotropic solids involving quadrupolar spins: Challenges and Perspectives.

Ganapathy V, Ramachandran R.

J Chem Phys. 2017 Oct 14;147(14):144202. doi: 10.1063/1.4993313.

PMID:
29031275
36.

L-Carnitine-conjugated nanoparticles to promote permeation across blood-brain barrier and to target glioma cells for drug delivery via the novel organic cation/carnitine transporter OCTN2.

Kou L, Hou Y, Yao Q, Guo W, Wang G, Wang M, Fu Q, He Z, Ganapathy V, Sun J.

Artif Cells Nanomed Biotechnol. 2018 Dec;46(8):1605-1616. doi: 10.1080/21691401.2017.1384385. Epub 2017 Oct 3.

PMID:
28974108
37.

Hydroxyurea differentially modulates activator and repressors of γ-globin gene in erythroblasts of responsive and non-responsive patients with sickle cell disease in correlation with Index of Hydroxyurea Responsiveness.

Zhu X, Hu T, Ho MH, Wang Y, Yu M, Patel N, Pi W, Choi JH, Xu H, Ganapathy V, Kutlar F, Kutlar A, Tuan D.

Haematologica. 2017 Dec;102(12):1995-2004. doi: 10.3324/haematol.2017.175646. Epub 2017 Sep 29.

38.

Carbidopa is an activator of aryl hydrocarbon receptor with potential for cancer therapy.

Ogura J, Miyauchi S, Shimono K, Yang S, Gonchigar S, Ganapathy V, Bhutia YD.

Biochem J. 2017 Sep 28;474(20):3391-3402. doi: 10.1042/BCJ20170583.

PMID:
28963435
39.

Dual targeting of l-carnitine-conjugated nanoparticles to OCTN2 and ATB0,+ to deliver chemotherapeutic agents for colon cancer therapy.

Kou L, Yao Q, Sivaprakasam S, Luo Q, Sun Y, Fu Q, He Z, Sun J, Ganapathy V.

Drug Deliv. 2017 Nov;24(1):1338-1349. doi: 10.1080/10717544.2017.1377316.

PMID:
28911246
40.

Prevalence of Low Peak Inspiratory Flow Rate at Discharge in Patients Hospitalized for COPD Exacerbation.

Sharma G, Mahler DA, Mayorga VM, Deering KL, Harshaw O, Ganapathy V.

Chronic Obstr Pulm Dis. 2017 Jul 15;4(3):217-224. doi: 10.15326/jcopdf.4.3.2017.0183.

41.

Monomethyl fumarate inhibits pain behaviors and amygdala activity in a rat arthritis model.

Kim H, Thompson J, Ji G, Ganapathy V, Neugebauer V.

Pain. 2017 Dec;158(12):2376-2385. doi: 10.1097/j.pain.0000000000001042.

42.

Cell-Surface and Nuclear Receptors in the Colon as Targets for Bacterial Metabolites and Its Relevance to Colon Health.

Sivaprakasam S, Bhutia YD, Ramachandran S, Ganapathy V.

Nutrients. 2017 Aug 10;9(8). pii: E856. doi: 10.3390/nu9080856. Review.

43.

Confidence in correct inhaler technique and its association with treatment adherence and health status among US patients with chronic obstructive pulmonary disease.

Amin AN, Ganapathy V, Roughley A, Small M.

Patient Prefer Adherence. 2017 Jul 12;11:1205-1212. doi: 10.2147/PPA.S140139. eCollection 2017.

44.

Health resource utilization for inpatients with COPD treated with nebulized arformoterol or nebulized formoterol.

Ganapathy V, Stensland MD.

Int J Chron Obstruct Pulmon Dis. 2017 Jun 20;12:1793-1801. doi: 10.2147/COPD.S134145. eCollection 2017.

45.

Cotransporting Ion is a Trigger for Cellular Endocytosis of Transporter-Targeting Nanoparticles: A Case Study of High-Efficiency SLC22A5 (OCTN2)-Mediated Carnitine-Conjugated Nanoparticles for Oral Delivery of Therapeutic Drugs.

Kou L, Yao Q, Sun M, Wu C, Wang J, Luo Q, Wang G, Du Y, Fu Q, Wang J, He Z, Ganapathy V, Sun J.

Adv Healthc Mater. 2017 Sep;6(17). doi: 10.1002/adhm.201700165. Epub 2017 Jun 29.

PMID:
28661032
46.

Electronic cigarette aerosols suppress cellular antioxidant defenses and induce significant oxidative DNA damage.

Ganapathy V, Manyanga J, Brame L, McGuire D, Sadhasivam B, Floyd E, Rubenstein DA, Ramachandran I, Wagener T, Queimado L.

PLoS One. 2017 May 18;12(5):e0177780. doi: 10.1371/journal.pone.0177780. eCollection 2017.

47.

Cell-surface G-protein-coupled receptors for tumor-associated metabolites: A direct link to mitochondrial dysfunction in cancer.

Ristic B, Bhutia YD, Ganapathy V.

Biochim Biophys Acta Rev Cancer. 2017 Aug;1868(1):246-257. doi: 10.1016/j.bbcan.2017.05.003. Epub 2017 May 13. Review.

48.

Gut Microbiome and Colon Cancer: Role of Bacterial Metabolites and Their Molecular Targets in the Host.

Bhutia YD, Ogura J, Sivaprakasam S, Ganapathy V.

Curr Colorectal Cancer Rep. 2017 Apr;13(2):111-118. doi: 10.1007/s11888-017-0362-9. Epub 2017 Feb 22.

49.

Plasma Membrane Na⁺-Coupled Citrate Transporter (SLC13A5) and Neonatal Epileptic Encephalopathy.

Bhutia YD, Kopel JJ, Lawrence JJ, Neugebauer V, Ganapathy V.

Molecules. 2017 Feb 28;22(3). pii: E378. doi: 10.3390/molecules22030378. Review.

50.

Influence of postoperative sagittal balance and spinopelvic parameters on the outcome of patients surgically treated for degenerative lumbar spondylolisthesis.

Radovanovic I, Urquhart JC, Ganapathy V, Siddiqi F, Gurr KR, Bailey SI, Bailey CS.

J Neurosurg Spine. 2017 Apr;26(4):448-453. doi: 10.3171/2016.9.SPINE1680. Epub 2017 Jan 20.

PMID:
28106523

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