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Virus genomes reveal factors that spread and sustained the Ebola epidemic. Dudas G et al. Nature. (2017)

Long Noncoding RNA MANTIS Facilitates Endothelial Angiogenic Function. Leisegang MS et al. Circulation. (2017)

Real-time, portable genome sequencing for Ebola surveillance. Quick J et al. Nature. (2016)

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Items: 1 to 50 of 628


Role of MIF and D-DT in immune-inflammatory, autoimmune, and chronic respiratory diseases: from pathogenic factors to therapeutic targets.

Günther S, Fagone P, Jalce G, Atanasov A, Guignabert C, Nicoletti F.

Drug Discov Today. 2018 Nov 12. pii: S1359-6446(18)30329-5. doi: 10.1016/j.drudis.2018.11.003. [Epub ahead of print] Review.


Asparaginyl Endopeptidase (Legumain) Supports Human Th1 Induction via Cathepsin L-Mediated Intracellular C3 Activation.

Freeley S, Cardone J, Günther SC, West EE, Reinheckel T, Watts C, Kemper C, Kolev MV.

Front Immunol. 2018 Oct 24;9:2449. doi: 10.3389/fimmu.2018.02449. eCollection 2018.


Tumour-infiltrating neutrophils counteract anti-VEGF therapy in metastatic colorectal cancer.

Schiffmann LM, Fritsch M, Gebauer F, Günther SD, Stair NR, Seeger JM, Thangarajah F, Dieplinger G, Bludau M, Alakus H, Göbel H, Quaas A, Zander T, Hilberg F, Bruns CJ, Kashkar H, Coutelle O.

Br J Cancer. 2018 Oct 31. doi: 10.1038/s41416-018-0198-3. [Epub ahead of print]


Biochemical and structural studies reveal differences and commonalities among cap-snatching endonucleases from segmented negative-strand RNA viruses.

Holm T, Kopicki JD, Busch C, Olschewski S, Rosenthal M, Uetrecht C, Günther S, Reindl S.

J Biol Chem. 2018 Oct 22. pii: jbc.RA118.004373. doi: 10.1074/jbc.RA118.004373. [Epub ahead of print]


Loss of pyruvate kinase M2 limits growth and triggers innate immune signaling in endothelial cells.

Stone OA, El-Brolosy M, Wilhelm K, Liu X, Romão AM, Grillo E, Lai JKH, Günther S, Jeratsch S, Kuenne C, Lee IC, Braun T, Santoro MM, Locasale JW, Potente M, Stainier DYR.

Nat Commun. 2018 Oct 9;9(1):4077. doi: 10.1038/s41467-018-06406-8.


Bromodomain Drug Discovery - the Past, the Present, and the Future.

Pervaiz M, Mishra P, Günther S.

Chem Rec. 2018 Oct 5. doi: 10.1002/tcr.201800074. [Epub ahead of print] Review.


Long-Term Biogas Production from Glycolate by Diverse and Highly Dynamic Communities.

Günther S, Becker D, Hübschmann T, Reinert S, Kleinsteuber S, Müller S, Wilhelm C.

Microorganisms. 2018 Oct 4;6(4). pii: E103. doi: 10.3390/microorganisms6040103.


Acute Abdomen in Pediatric Patients With Lassa Fever: Prevalence and Response to Nonoperative Management.

Akpede GO, Adetunji AE, Udefiagbon EO, Eluehike SO, Odike AI, Ewah-Odiase RO, Omosofe FO, Akerele JM, Atafo RO, Okonofua MO, Onyeke I, Oyedeji OA, Mbanefo K, Ogbaini-Emovon E, Okokhere PO, Günther S, Dongo AE.

J Pediatric Infect Dis Soc. 2018 Sep 28. doi: 10.1093/jpids/piy093. [Epub ahead of print]


Toward genome editing in X-linked RP-development of a mouse model with specific treatment relevant features.

Schlegel J, Hoffmann J, Röll D, Müller B, Günther S, Zhang W, Janise A, Vössing C, Fühler B, Neidhardt J, Khanna H, Lorenz B, Stieger K.

Transl Res. 2018 Aug 24. pii: S1931-5244(18)30141-5. doi: 10.1016/j.trsl.2018.08.006. [Epub ahead of print]


Single Muscle Fiber Proteomics Reveals Distinct Protein Changes in Slow and Fast Fibers during Muscle Atrophy.

Lang F, Khaghani S, Türk C, Wiederstein JL, Hölper S, Piller T, Nogara L, Blaauw B, Günther S, Müller S, Braun T, Krüger M.

J Proteome Res. 2018 Oct 5;17(10):3333-3347. doi: 10.1021/acs.jproteome.8b00093. Epub 2018 Sep 5.


Kinetics of Soluble Mediators of the Host Response in Ebola Virus Disease.

Kerber R, Krumkamp R, Korva M, Rieger T, Wurr S, Duraffour S, Oestereich L, Gabriel M, Sissoko D, Anglaret X, Malvy D, May J, Županc TA, Muñoz-Fontela C, Günther S.

J Infect Dis. 2018 Aug 8. doi: 10.1093/infdis/jiy429. [Epub ahead of print]


Case series of successful treatment with fecal microbiota transplant (FMT) oral capsules mixed from multiple donors even in patients previously treated with FMT enemas for recurrent Clostridium difficile infection.

Chehri M, Christensen AH, Halkjær SI, Günther S, Petersen AM, Helms M.

Medicine (Baltimore). 2018 Aug;97(31):e11706. doi: 10.1097/MD.0000000000011706.


The European Virus Archive goes global: A growing resource for research.

Romette JL, Prat CM, Gould EA, de Lamballerie X, Charrel R, Coutard B, Fooks AR, Bardsley M, Carroll M, Drosten C, Drexler JF, Günther S, Klempa B, Pinschewer D, Klimkait T, Avsic-Zupanc T, Capobianchi MR, Dicaro A, Ippolito G, Nitsche A, Koopmans M, Reusken C, Gorbalenya A, Raoul H, Bourhy H, Mettenleiter T, Reiche S, Batten C, Sabeta C, Paweska JT, Eropkin M, Zverev V, Hu Z, Mac Cullough S, Mirazimi A, Pradel F, Lieutaud P.

Antiviral Res. 2018 Oct;158:127-134. doi: 10.1016/j.antiviral.2018.07.017. Epub 2018 Jul 29. Review.


Acute Lassa Virus Encephalitis with Lassa Virus in the Cerebrospinal Fluid but Absent in the Blood: A Case Report with a Positive Outcome.

Okokhere PO, Erameh CO, Alikah F, Akhideno PE, Iruolagbe CO, Osazuwa OO, Bankole IA, Adomeh DI, Odia I, Aire CO, Oyakhilome J, Agbukor J, Atafo RO, Asogun DA, Happi CT, Sabeti PC, Günther S, Akpede GO.

Case Rep Neurol. 2018 Jul 3;10(2):150-158. doi: 10.1159/000490374. eCollection 2018 May-Aug.


Imaging the confined surface oxidation of Ni3Al(111) by in situ high temperature scanning tunneling microscopy.

Ma X, Günther S.

Phys Chem Chem Phys. 2018 Aug 29;20(34):21844-21855. doi: 10.1039/c8cp03197e.


Viral metagenomics, genetic and evolutionary characteristics of Crimean-Congo hemorrhagic fever orthonairovirus in humans, Kosovo.

Emmerich P, Jakupi X, von Possel R, Berisha L, Halili B, Günther S, Cadar D, Ahmeti S, Schmidt-Chanasit J.

Infect Genet Evol. 2018 Nov;65:6-11. doi: 10.1016/j.meegid.2018.07.010. Epub 2018 Jul 11.


Widespread arenavirus occurrence and seroprevalence in small mammals, Nigeria.

Olayemi A, Oyeyiola A, Obadare A, Igbokwe J, Adesina AS, Onwe F, Ukwaja KN, Ajayi NA, Rieger T, Günther S, Fichet-Calvet E.

Parasit Vectors. 2018 Jul 13;11(1):416. doi: 10.1186/s13071-018-2991-5.


T-Cell Receptor Diversity and the Control of T-Cell Homeostasis Mark Ebola Virus Disease Survival in Humans.

Speranza E, Ruibal P, Port JR, Feng F, Burkhardt L, Grundhoff A, Günther S, Oestereich L, Hiscox JA, Connor JH, Muñoz-Fontela C.

J Infect Dis. 2018 Jul 6. doi: 10.1093/infdis/jiy352. [Epub ahead of print]


Faecal microbiota transplantation alters gut microbiota in patients with irritable bowel syndrome: results from a randomised, double-blind placebo-controlled study.

Halkjær SI, Christensen AH, Lo BZS, Browne PD, Günther S, Hansen LH, Petersen AM.

Gut. 2018 Dec;67(12):2107-2115. doi: 10.1136/gutjnl-2018-316434. Epub 2018 Jul 6.


New insights into the structural dynamics of the kinase JNK3.

Mishra P, Günther S.

Sci Rep. 2018 Jun 21;8(1):9435. doi: 10.1038/s41598-018-27867-3.


Application of the Six Sigma concept for quality assessment of different strategies in DBS surgery.

Polanski WH, Martin KD, Günther S, Schackert G, Klingelhoefer L, Fauser M, Storch A, Sobottka SB.

Int J Qual Health Care. 2018 Jun 18. doi: 10.1093/intqhc/mzy129. [Epub ahead of print]


Educational inequalities in subjective health in Germany from 1994 to 2014: a trend analysis using the German Socio-Economic Panel study (GSOEP).

Moor I, Günther S, Knöchelmann A, Hoebel J, Pförtner TK, Lampert T, Richter M.

BMJ Open. 2018 Jun 8;8(6):e019755. doi: 10.1136/bmjopen-2017-019755.


MiCEE is a ncRNA-protein complex that mediates epigenetic silencing and nucleolar organization.

Singh I, Contreras A, Cordero J, Rubio K, Dobersch S, Günther S, Jeratsch S, Mehta A, Krüger M, Graumann J, Seeger W, Dobreva G, Braun T, Barreto G.

Nat Genet. 2018 Jul;50(7):990-1001. doi: 10.1038/s41588-018-0139-3. Epub 2018 Jun 4.


Reg proteins direct accumulation of functionally distinct macrophage subsets after myocardial infarction.

Lörchner H, Hou Y, Adrian-Segarra JM, Kulhei J, Detzer J, Günther S, Gajawada P, Warnecke H, Niessen HW, Pöling J, Braun T.

Cardiovasc Res. 2018 Oct 1;114(12):1667-1679. doi: 10.1093/cvr/cvy126.


Remote excitation and detection of surface-enhanced Raman scattering from graphene.

Coca-López N, Hartmann NF, Mancabelli T, Kraus J, Günther S, Comin A, Hartschuh A.

Nanoscale. 2018 Jun 7;10(22):10498-10504. doi: 10.1039/c8nr02174k.


The Hippo pathway effector Wwtr1 regulates cardiac wall maturation in zebrafish.

Lai JKH, Collins MM, Uribe V, Jiménez-Amilburu V, Günther S, Maischein HM, Stainier DYR.

Development. 2018 May 17;145(10). pii: dev159210. doi: 10.1242/dev.159210.


Author Correction: SMARCA2-regulated host cell factors are required for MxA restriction of influenza A viruses.

Dornfeld D, Dudek AH, Vausselin T, Günther SC, Hultquist JF, Giese S, Khokhlova-Cubberley D, Chew YC, Pache L, Krogan NJ, Garcia-Sastre A, Schwemmle M, Shaw ML.

Sci Rep. 2018 May 14;8(1):7782. doi: 10.1038/s41598-018-25858-y.


Skeletal Muscle-Specific Methyltransferase METTL21C Trimethylates p97 and Regulates Autophagy-Associated Protein Breakdown.

Wiederstein JL, Nolte H, Günther S, Piller T, Baraldo M, Kostin S, Bloch W, Schindler N, Sandri M, Blaauw B, Braun T, Hölper S, Krüger M.

Cell Rep. 2018 May 1;23(5):1342-1356. doi: 10.1016/j.celrep.2018.03.136.


Metabolic Maturation during Muscle Stem Cell Differentiation Is Achieved by miR-1/133a-Mediated Inhibition of the Dlk1-Dio3 Mega Gene Cluster.

Wüst S, Dröse S, Heidler J, Wittig I, Klockner I, Franko A, Bonke E, Günther S, Gärtner U, Boettger T, Braun T.

Cell Metab. 2018 May 1;27(5):1026-1039.e6. doi: 10.1016/j.cmet.2018.02.022. Epub 2018 Apr 5.


Switch in Laminin β2 to Laminin β1 Isoforms During Aging Controls Endothelial Cell Functions-Brief Report.

Wagner JUG, Chavakis E, Rogg EM, Muhly-Reinholz M, Glaser SF, Günther S, John D, Bonini F, Zeiher AM, Schaefer L, Hannocks MJ, Boon RA, Dimmeler S.

Arterioscler Thromb Vasc Biol. 2018 May;38(5):1170-1177. doi: 10.1161/ATVBAHA.117.310685. Epub 2018 Mar 29.


Gene expression profiling of human bronchial epithelial cells exposed to fine particulate matter (PM2.5) from biomass combustion.

Popadić D, Heßelbach K, Richter-Brockmann S, Kim GJ, Flemming S, Schmidt-Heck W, Häupl T, Bonin M, Dornhof R, Achten C, Günther S, Humar M, Merfort I.

Toxicol Appl Pharmacol. 2018 May 15;347:10-22. doi: 10.1016/j.taap.2018.03.024. Epub 2018 Mar 26. No abstract available.


Development and evaluation of antibody-capture immunoassays for detection of Lassa virus nucleoprotein-specific immunoglobulin M and G.

Gabriel M, Adomeh DI, Ehimuan J, Oyakhilome J, Omomoh EO, Ighodalo Y, Olokor T, Bonney K, Pahlmann M, Emmerich P, Lelke M, Brunotte L, Ölschläger S, Thomé-Bolduan C, Becker-Ziaja B, Busch C, Odia I, Ogbaini-Emovon E, Okokhere PO, Okogbenin SA, Akpede GO, Schmitz H, Asogun DA, Günther S.

PLoS Negl Trop Dis. 2018 Mar 29;12(3):e0006361. doi: 10.1371/journal.pntd.0006361. eCollection 2018 Mar.


Field investigation with real-time virus genetic characterisation support of a cluster of Ebola virus disease cases in Dubréka, Guinea, April to June 2015.

Pini A, Zomahoun D, Duraffour S, Derrough T, Charles M, Quick J, Loman N, Cowley L, Leno M, Ouedraogo N, Thiam O, Hernández-Romieu A, Iko A, Keita H, Konate D, Soumah AA, Bouchouar E, Ileka-Priouzeau S, Keita S, Diallo B, Cisse F, Jansa J, Carroll M, Günther S, Severi E, Formenty P.

Euro Surveill. 2018 Mar;23(12). doi: 10.2807/1560-7917.ES.2018.23.12.17-00140.


Antiviral efficacy of favipiravir against Ebola virus: A translational study in cynomolgus macaques.

Guedj J, Piorkowski G, Jacquot F, Madelain V, Nguyen THT, Rodallec A, Gunther S, Carbonnelle C, Mentré F, Raoul H, de Lamballerie X.

PLoS Med. 2018 Mar 27;15(3):e1002535. doi: 10.1371/journal.pmed.1002535. eCollection 2018 Mar.


Sensitive and specific detection of Crimean-Congo Hemorrhagic Fever Virus (CCHFV)-Specific IgM and IgG antibodies in human sera using recombinant CCHFV nucleoprotein as antigen in μ-capture and IgG immune complex (IC) ELISA tests.

Emmerich P, Mika A, von Possel R, Rackow A, Liu Y, Schmitz H, Günther S, Sherifi K, Halili B, Jakupi X, Berisha L, Ahmeti S, Deschermeier C.

PLoS Negl Trop Dis. 2018 Mar 26;12(3):e0006366. doi: 10.1371/journal.pntd.0006366. eCollection 2018 Mar.


Transmission of microRNA antimiRs to mouse offspring via the maternal-placental-fetal unit.

Hönig J, Mižíková I, Nardiello C, Surate Solaligue DE, Daume MJ, Vadász I, Mayer K, Herold S, Günther S, Seeger W, Morty RE.

RNA. 2018 Jun;24(6):865-879. doi: 10.1261/rna.063206.117. Epub 2018 Mar 14.


Detection of feline Coronavirus in effusions of cats with and without feline infectious peritonitis using loop-mediated isothermal amplification.

Günther S, Felten S, Wess G, Hartmann K, Weber K.

J Virol Methods. 2018 Jun;256:32-36. doi: 10.1016/j.jviromet.2018.03.003. Epub 2018 Mar 11.


Early Fitting in Cochlear Implantation: Benefits and Limits.

Günther S, Baumann U, Stöver T.

Otol Neurotol. 2018 Apr;39(4):e250-e256. doi: 10.1097/MAO.0000000000001745.


Clinical and laboratory predictors of Lassa fever outcome in a dedicated treatment facility in Nigeria: a retrospective, observational cohort study.

Okokhere P, Colubri A, Azubike C, Iruolagbe C, Osazuwa O, Tabrizi S, Chin E, Asad S, Ediale E, Rafiu M, Adomeh D, Odia I, Atafo R, Aire C, Okogbenin S, Pahlman M, Becker-Ziaja B, Asogun D, Fradet T, Fry B, Schaffner SF, Happi C, Akpede G, Günther S, Sabeti PC.

Lancet Infect Dis. 2018 Jun;18(6):684-695. doi: 10.1016/S1473-3099(18)30121-X. Epub 2018 Mar 6. Erratum in: Lancet Infect Dis. 2018 Mar 16;:.


New Lineage of Lassa Virus, Togo, 2016.

Whitmer SLM, Strecker T, Cadar D, Dienes HP, Faber K, Patel K, Brown SM, Davis WG, Klena JD, Rollin PE, Schmidt-Chanasit J, Fichet-Calvet E, Noack B, Emmerich P, Rieger T, Wolff S, Fehling SK, Eickmann M, Mengel JP, Schultze T, Hain T, Ampofo W, Bonney K, Aryeequaye JND, Ribner B, Varkey JB, Mehta AK, Lyon GM 3rd, Kann G, De Leuw P, Schuettfort G, Stephan C, Wieland U, Fries JWU, Kochanek M, Kraft CS, Wolf T, Nichol ST, Becker S, Ströher U, Günther S.

Emerg Infect Dis. 2018 Mar;24(3):599-602. doi: 10.3201/eid2403.171905.


RV Fractional Area Change and TAPSE as Predictors of Severe Right Ventricular Dysfunction in Pulmonary Hypertension: A CMR Study.

Hoette S, Creuzé N, Günther S, Montani D, Savale L, Jaïs X, Parent F, Sitbon O, Rochitte CE, Simonneau G, Humbert M, Souza R, Chemla D.

Lung. 2018 Apr;196(2):157-164. doi: 10.1007/s00408-018-0089-7. Epub 2018 Feb 12.


Arenavirus infection correlates with lower survival of its natural rodent host in a long-term capture-mark-recapture study.

Mariën J, Sluydts V, Borremans B, Gryseels S, Vanden Broecke B, Sabuni CA, Katakweba AAS, Mulungu LS, Günther S, de Bellocq JG, Massawe AW, Leirs H.

Parasit Vectors. 2018 Feb 8;11(1):90. doi: 10.1186/s13071-018-2674-2.


SMARCA2-regulated host cell factors are required for MxA restriction of influenza A viruses.

Dornfeld D, Dudek AH, Vausselin T, Günther SC, Hultquist JF, Giese S, Khokhlova-Cubberley D, Chew YC, Pache L, Krogan NJ, Garcia-Sastre A, Schwemmle M, Shaw ML.

Sci Rep. 2018 Feb 1;8(1):2092. doi: 10.1038/s41598-018-20458-2. Erratum in: Sci Rep. 2018 May 14;8(1):7782.


Ecological Stability Properties of Microbial Communities Assessed by Flow Cytometry.

Liu Z, Cichocki N, Bonk F, Günther S, Schattenberg F, Harms H, Centler F, Müller S.

mSphere. 2018 Jan 17;3(1). pii: e00564-17. doi: 10.1128/mSphere.00564-17. eCollection 2018 Jan-Feb.


Clonal Expansion of Endothelial Cells Contributes to Ischemia-Induced Neovascularization.

Manavski Y, Lucas T, Glaser SF, Dorsheimer L, Günther S, Braun T, Rieger MA, Zeiher AM, Boon RA, Dimmeler S.

Circ Res. 2018 Mar 2;122(5):670-677. doi: 10.1161/CIRCRESAHA.117.312310. Epub 2018 Jan 22.


Early Risk Stratification in Patients With Cardiogenic Shock Complicating Acute Myocardial Infarction Treated With Extracorporeal Life Support and Primary Percutaneous Coronary Intervention.

Vdovin N, Günther SPW, de Waha S, Seizer P, Brunner S, Schlensak C, Thiele H, Hagl C, Massberg S, Bauer A.

JACC Cardiovasc Interv. 2017 Dec 11;10(23):2469-2471. doi: 10.1016/j.jcin.2017.08.055. No abstract available.


[Gut microbiota and depressive symptoms].

Knudsen JK, Jensen ZF, Christensen AH, Günther S, Nielsen LN, Deutscher P, Arnfred S.

Ugeskr Laeger. 2017 Nov 20;179(47). pii: V11160854. Danish.


Members of Bitter Taste Receptor Cluster Tas2r143/Tas2r135/Tas2r126 Are Expressed in the Epithelium of Murine Airways and Other Non-gustatory Tissues.

Liu S, Lu S, Xu R, Atzberger A, Günther S, Wettschureck N, Offermanns S.

Front Physiol. 2017 Oct 30;8:849. doi: 10.3389/fphys.2017.00849. eCollection 2017.


Point-of-care B-type natriuretic peptide and portable echocardiography for assessment of patients with suspected heart failure in primary care: rationale and design of the three-part Handheld-BNP program and results of the training study.

Morbach C, Buck T, Rost C, Peter S, Günther S, Störk S, Prettin C, Erbel R, Ertl G, Angermann CE; Handheld-BNP Research Network.

Clin Res Cardiol. 2018 Feb;107(2):95-107. doi: 10.1007/s00392-017-1181-3. Epub 2017 Nov 15.


[Intergenerational mobility and health inequalities in East and West Germany : A trend analysis from 1992 to 2012].

Günther S, Moor I, Knöchelmann A, Richter M.

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2018 Jan;61(1):78-88. doi: 10.1007/s00103-017-2655-1. German.


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