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Items: 1 to 50 of 477

1.

Fabrication of a Monolithic Lab-on-a-Chip Platform with Integrated Hydrogel Waveguides for Chemical Sensing.

Torres-Mapa ML, Singh M, Simon O, Mapa JL, Machida M, Günther A, Roth B, Heinemann D, Terakawa M, Heisterkamp A.

Sensors (Basel). 2019 Oct 8;19(19). pii: E4333. doi: 10.3390/s19194333.

2.

Association of Surgical Hematoma Evacuation vs Conservative Treatment With Functional Outcome in Patients With Cerebellar Intracerebral Hemorrhage.

Kuramatsu JB, Biffi A, Gerner ST, Sembill JA, Sprügel MI, Leasure A, Sansing L, Matouk C, Falcone GJ, Endres M, Haeusler KG, Sobesky J, Schurig J, Zweynert S, Bauer M, Vajkoczy P, Ringleb PA, Purrucker J, Rizos T, Volkmann J, Müllges W, Kraft P, Schubert AL, Erbguth F, Nueckel M, Schellinger PD, Glahn J, Knappe UJ, Fink GR, Dohmen C, Stetefeld H, Fisse AL, Minnerup J, Hagemann G, Rakers F, Reichmann H, Schneider H, Rahmig J, Ludolph AC, Stösser S, Neugebauer H, Röther J, Michels P, Schwarz M, Reimann G, Bäzner H, Schwert H, Claßen J, Michalski D, Grau A, Palm F, Urbanek C, Wöhrle JC, Alshammari F, Horn M, Bahner D, Witte OW, Günther A, Hamann GF, Hagen M, Roeder SS, Lücking H, Dörfler A, Testai FD, Woo D, Schwab S, Sheth KN, Huttner HB.

JAMA. 2019 Oct 8;322(14):1392-1403. doi: 10.1001/jama.2019.13014.

PMID:
31593272
3.

IRE1 Signaling As a Putative Therapeutic Target in Influenza Virus-induced Pneumonia.

Schmoldt C, Vazquez-Armendariz AI, Shalashova I, Selvakumar B, Bremer CM, Peteranderl C, Wasnick R, Witte B, Gattenlöhner S, Fink L, Vadász I, Morty RE, Pleschka S, Seeger W, Günther A, Herold S.

Am J Respir Cell Mol Biol. 2019 Oct;61(4):537-540. doi: 10.1165/rcmb.2019-0123LE. No abstract available.

PMID:
31573336
4.

Provenance for Biomedical Ontologies with RDF and Git.

Stöhr MR, Günther A, Majeed RW.

Stud Health Technol Inform. 2019 Sep 3;267:230-237. doi: 10.3233/SHTI190832.

PMID:
31483277
5.

Verifying Data Integration Configurations for Semantical Correctness and Completeness.

Stöhr MR, Günther A, Majeed RW.

Stud Health Technol Inform. 2019 Sep 3;267:66-73. doi: 10.3233/SHTI190807.

PMID:
31483256
6.

[Intensive care aspects of autoimmune encephalitis].

Günther A, Schubert J, Witte OW, Brämer D.

Med Klin Intensivmed Notfmed. 2019 Oct;114(7):620-627. doi: 10.1007/s00063-019-0604-5. Epub 2019 Aug 27. Review. German.

PMID:
31456008
7.

The Effect of Endovascular Thrombectomy Studies on the Decision to Transfer Patients in a Telestroke Network.

Klingner C, Tinschert P, Brodoehl S, Berrouschot J, Witte OW, Günther A, Klingner CM.

Telemed J E Health. 2019 Jul 19. doi: 10.1089/tmj.2019.0067. [Epub ahead of print]

PMID:
31329520
8.

Metformin induces lipogenic differentiation in myofibroblasts to reverse lung fibrosis.

Kheirollahi V, Wasnick RM, Biasin V, Vazquez-Armendariz AI, Chu X, Moiseenko A, Weiss A, Wilhelm J, Zhang JS, Kwapiszewska G, Herold S, Schermuly RT, Mari B, Li X, Seeger W, Günther A, Bellusci S, El Agha E.

Nat Commun. 2019 Jul 5;10(1):2987. doi: 10.1038/s41467-019-10839-0.

9.

T Cell-Specific Overexpression of Acid Sphingomyelinase Results in Elevated T Cell Activation and Reduced Parasitemia During Plasmodium yoelii Infection.

Hose M, Günther A, Abberger H, Begum S, Korencak M, Becker KA, Buer J, Westendorf AM, Hansen W.

Front Immunol. 2019 May 31;10:1225. doi: 10.3389/fimmu.2019.01225. eCollection 2019.

10.

The oncogene ECT2 contributes to a hyperplastic, proliferative lung epithelial cell phenotype in IPF.

Ulke HM, Mutze K, Lehmann M, Wagner DE, Heinzelmann K, Günther A, Eickelberg O, Königshoff M.

Am J Respir Cell Mol Biol. 2019 May 30. doi: 10.1165/rcmb.2019-0047OC. [Epub ahead of print]

PMID:
31145635
11.

The Ariane-IPF ERS Clinical Research Collaboration: seeking collaboration through launch of a federation of European registries on idiopathic pulmonary fibrosis.

Cottin V, Annesi-Maesano I, Günther A, Galvin L, Kreuter M, Powell P, Prasse A, Reynolds G, Richeldi L, Spagnolo P, Valenzuela C, Wijsenbeek M, Wuyts WA, Crestani B; Ariane-IPF Clinical Research Collaboration consortium.

Eur Respir J. 2019 May 23;53(5). pii: 1900539. doi: 10.1183/13993003.00539-2019. Print 2019 May. No abstract available.

PMID:
31123022
12.

Inactivation of nuclear histone deacetylases by EP300 disrupts the MiCEE complex in idiopathic pulmonary fibrosis.

Rubio K, Singh I, Dobersch S, Sarvari P, Günther S, Cordero J, Mehta A, Wujak L, Cabrera-Fuentes H, Chao CM, Braubach P, Bellusci S, Seeger W, Günther A, Preissner KT, Wygrecka M, Savai R, Papy-Garcia D, Dobreva G, Heikenwalder M, Savai-Pullamsetti S, Braun T, Barreto G.

Nat Commun. 2019 May 20;10(1):2229. doi: 10.1038/s41467-019-10066-7.

13.

Characteristics in Non-Vitamin K Antagonist Oral Anticoagulant-Related Intracerebral Hemorrhage.

Gerner ST, Kuramatsu JB, Sembill JA, Sprügel MI, Hagen M, Knappe RU, Endres M, Haeusler KG, Sobesky J, Schurig J, Zweynert S, Bauer M, Vajkoczy P, Ringleb PA, Purrucker JC, Rizos T, Volkmann J, Müllges W, Kraft P, Schubert AL, Erbguth F, Nueckel M, Schellinger PD, Glahn J, Knappe UJ, Fink GR, Dohmen C, Stetefeld H, Fisse AL, Minnerup J, Hagemann G, Rakers F, Reichmann H, Schneider H, Rahmig J, Ludolph AC, Stösser S, Neugebauer H, Röther J, Michels P, Schwarz M, Reimann G, Bäzner H, Schwert H, Claßen J, Michalski D, Grau A, Palm F, Urbanek C, Wöhrle JC, Alshammari F, Horn M, Bahner D, Witte OW, Günther A, Hamann GF, Engelhorn T, Lücking H, Dörfler A, Schwab S, Huttner HB.

Stroke. 2019 Jun;50(6):1392-1402. doi: 10.1161/STROKEAHA.118.023492. Epub 2019 May 16.

PMID:
31092170
14.

FGF10-FGFR2B Signaling Generates Basal Cells and Drives Alveolar Epithelial Regeneration by Bronchial Epithelial Stem Cells after Lung Injury.

Yuan T, Volckaert T, Redente EF, Hopkins S, Klinkhammer K, Wasnick R, Chao CM, Yuan J, Zhang JS, Yao C, Majka S, Stripp BR, Günther A, Riches DWH, Bellusci S, Thannickal VJ, De Langhe SP.

Stem Cell Reports. 2019 May 14;12(5):1041-1055. doi: 10.1016/j.stemcr.2019.04.003. Epub 2019 May 2.

15.

[New transplantation law: how does one provide relatives with appropriate support?]

Deffner T, Brauer M, Günther A, Michels G.

Med Klin Intensivmed Notfmed. 2019 Jun;114(5):470-472. doi: 10.1007/s00063-019-0585-4. German. No abstract available.

PMID:
31049598
16.

Altered proteasome function in right ventricular hypertrophy.

Heitmeier T, Sydykov A, Lukas C, Vroom C, Korfei M, Petrovic A, Klingel K, Günther A, Eickelberg O, Weissmann N, Ghofrani HA, Seeger W, Grimminger F, Schermuly RT, Meiners S, Kosanovic D.

Cardiovasc Res. 2019 Apr 24. pii: cvz103. doi: 10.1093/cvr/cvz103. [Epub ahead of print]

PMID:
31020333
17.

The Long Noncoding RNA DNM3OS Is a Reservoir of FibromiRs with Major Functions in Lung Fibroblast Response to TGF-β and Pulmonary Fibrosis.

Savary G, Dewaeles E, Diazzi S, Buscot M, Nottet N, Fassy J, Courcot E, Henaoui IS, Lemaire J, Martis N, Van der Hauwaert C, Pons N, Magnone V, Leroy S, Hofman V, Plantier L, Lebrigand K, Paquet A, Lino Cardenas CL, Vassaux G, Hofman P, Günther A, Crestani B, Wallaert B, Rezzonico R, Brousseau T, Glowacki F, Bellusci S, Perrais M, Broly F, Barbry P, Marquette CH, Cauffiez C, Mari B, Pottier N.

Am J Respir Crit Care Med. 2019 Jul 15;200(2):184-198. doi: 10.1164/rccm.201807-1237OC.

PMID:
30964696
18.

Cause or effect: Altered brain and network activity in cervical dystonia is partially normalized by botulinum toxin treatment.

Brodoehl S, Wagner F, Prell T, Klingner C, Witte OW, Günther A.

Neuroimage Clin. 2019;22:101792. doi: 10.1016/j.nicl.2019.101792. Epub 2019 Mar 26.

19.

[Emergency care in nursing homes in the City of Braunschweig: A cross-sectoral view with indicators from deaths, resuscitation, emergency department visits and EMS deployment].

Günther A, Schmid S, Weidlich-Wichmann U, Bleidorn J, Buhr-Riehm B, Schubert R, Schwartze J, Schneider N, Hasseler M.

Z Evid Fortbild Qual Gesundhwes. 2019 May;141-142:1-10. doi: 10.1016/j.zefq.2019.02.010. Epub 2019 Mar 26. German.

PMID:
30922714
20.

[Chronic fibrosing lung diseases : Idiopathic pulmonary fibrosis from the perspective of its differential diagnosis].

Dartsch RC, Fink L, Breithecker A, Markart P, Tello S, Seeger W, Günther A.

Internist (Berl). 2019 Apr;60(4):345-361. doi: 10.1007/s00108-019-0571-1. German.

PMID:
30887071
21.

Nanomedical Relevance of the Intermolecular Interaction Dynamics-Examples from Lysozymes and Insulins.

Zhang R, Zhang N, Mohri M, Wu L, Eckert T, Krylov VB, Antosova A, Ponikova S, Bednarikova Z, Markart P, Günther A, Norden B, Billeter M, Schauer R, Scheidig AJ, Ratha BN, Bhunia A, Hesse K, Enani MA, Steinmeyer J, Petridis AK, Kozar T, Gazova Z, Nifantiev NE, Siebert HC.

ACS Omega. 2019 Feb 28;4(2):4206-4220. doi: 10.1021/acsomega.8b02471. Epub 2019 Feb 27.

22.

Real-time fMRI neurofeedback training to improve eating behavior by self-regulation of the dorsolateral prefrontal cortex: A randomized controlled trial in overweight and obese subjects.

Kohl SH, Veit R, Spetter MS, Günther A, Rina A, Lührs M, Birbaumer N, Preissl H, Hallschmid M.

Neuroimage. 2019 May 1;191:596-609. doi: 10.1016/j.neuroimage.2019.02.033. Epub 2019 Feb 21.

PMID:
30798010
23.

Adipokine expression in systemic sclerosis lung and gastrointestinal organ involvement.

Neumann E, Lepper N, Vasile M, Riccieri V, Peters M, Meier F, Hülser ML, Distler O, Gay S, Mahavadi P, Günther A, Roeb E, Frommer KW, Diller M, Müller-Ladner U.

Cytokine. 2019 May;117:41-49. doi: 10.1016/j.cyto.2018.11.013. Epub 2019 Feb 19.

PMID:
30784899
24.

Comparison of Apnea Detection Using Oronasal Thermal Airflow Sensor, Nasal Pressure Transducer, Respiratory Inductance Plethysmography and Tracheal Sound Sensor.

Sabil A, Glos M, Günther A, Schöbel C, Veauthier C, Fietze I, Penzel T.

J Clin Sleep Med. 2019 Feb 15;15(2):285-292. doi: 10.5664/jcsm.7634.

25.

Apnea and hypopnea characterization using esophageal pressure, respiratory inductance plethysmography, and suprasternal pressure: a comparative study.

Sabil A, Schöbel C, Glos M, Gunther A, Veauthier C, Arens P, Fietze I, Penzel T.

Sleep Breath. 2019 Feb 7. doi: 10.1007/s11325-019-01793-8. [Epub ahead of print]

PMID:
30729405
26.

Measuring pain-Physiological and self-rated measurements in relation to pain stimulation and anxiety.

Storm H, Günther A, Sackey PV, Bernhardsson J, Bjärtå A.

Acta Anaesthesiol Scand. 2019 May;63(5):668-675. doi: 10.1111/aas.13323. Epub 2019 Jan 31.

PMID:
30701545
27.

Fused Filament Fabrication (FFF) of Metal-Ceramic Components.

Abel J, Scheithauer U, Janics T, Hampel S, Cano S, Müller-Köhn A, Günther A, Kukla C, Moritz T.

J Vis Exp. 2019 Jan 11;(143). doi: 10.3791/57693.

PMID:
30688295
28.

Very Low Frequency Heart Rate Variability Predicts the Development of Post-Stroke Infections.

Brämer D, Günther A, Rupprecht S, Nowack S, Adam J, Meyer F, Schwab M, Surber R, Witte OW, Hoyer H, Hoyer D.

Transl Stroke Res. 2019 Jan 7. doi: 10.1007/s12975-018-0684-1. [Epub ahead of print]

PMID:
30617993
29.

Talk About Thrombolysis. Regular Case-Based Discussions of Stroke Thrombolysis Improve Door-to-Needle Time by 20.

Klingner C, Günther A, Brodoehl S, Witte OW, Klingner CM.

J Stroke Cerebrovasc Dis. 2019 Apr;28(4):876-881. doi: 10.1016/j.jstrokecerebrovasdis.2018.12.002. Epub 2018 Dec 28.

PMID:
30598329
30.

Update of the evidence based, interdisciplinary guideline for anti-inflammatory treatment of uveitis associated with juvenile idiopathic arthritis.

Heiligenhaus A, Minden K, Tappeiner C, Baus H, Bertram B, Deuter C, Foeldvari I, Föll D, Frosch M, Ganser G, Gaubitz M, Günther A, Heinz C, Horneff G, Huemer C, Kopp I, Lommatzsch C, Lutz T, Michels H, Neß T, Neudorf U, Pleyer U, Schneider M, Schulze-Koops H, Thurau S, Zierhut M, Lehmann HW.

Semin Arthritis Rheum. 2019 Aug;49(1):43-55. doi: 10.1016/j.semarthrit.2018.11.004. Epub 2018 Dec 4. Review.

31.

HCN4 knockdown in dorsal hippocampus promotes anxiety-like behavior in mice.

Günther A, Luczak V, Gruteser N, Abel T, Baumann A.

Genes Brain Behav. 2019 Feb;18(2):e12550. doi: 10.1111/gbb.12550. Epub 2019 Jan 22.

PMID:
30585408
32.

Management and prognostic markers in patients with autoimmune encephalitis requiring ICU treatment.

Schubert J, Brämer D, Huttner HB, Gerner ST, Fuhrer H, Melzer N, Dik A, Prüss H, Ly LT, Fuchs K, Leypoldt F, Nissen G, Schirotzek I, Dohmen C, Bösel J, Lewerenz J, Thaler F, Kraft A, Juranek A, Ringelstein M, Sühs KW, Urbanek C, Scherag A, Geis C, Witte OW, Günther A; GENERATE and IGNITE network.

Neurol Neuroimmunol Neuroinflamm. 2018 Oct 30;6(1):e514. doi: 10.1212/NXI.0000000000000514. eCollection 2019 Jan.

33.

Blood glutamate EAAT2-cell grabbing therapy in cerebral ischemia.

Pérez-Mato M, Iglesias-Rey R, Vieites-Prado A, Dopico-López A, Argibay B, Fernández-Susavila H, da Silva-Candal A, Pérez-Díaz A, Correa-Paz C, Günther A, Ávila-Gómez P, Isabel Loza M, Baumann A, Castillo J, Sobrino T, Campos F.

EBioMedicine. 2019 Jan;39:118-131. doi: 10.1016/j.ebiom.2018.11.024. Epub 2018 Dec 13.

34.

The oral splicing modifier RG7800 increases full length survival of motor neuron 2 mRNA and survival of motor neuron protein: Results from trials in healthy adults and patients with spinal muscular atrophy.

Kletzl H, Marquet A, Günther A, Tang W, Heuberger J, Groeneveld GJ, Birkhoff W, Mercuri E, Lochmüller H, Wood C, Fischer D, Gerlach I, Heinig K, Bugawan T, Dziadek S, Kinch R, Czech C, Khwaja O.

Neuromuscul Disord. 2019 Jan;29(1):21-29. doi: 10.1016/j.nmd.2018.10.001. Epub 2018 Oct 30.

PMID:
30553700
35.

[How many potential organ donors are there really? : Retrospective analysis of why determination of irreversible loss of brain function was not performed in deceased patients with relevant brain damage].

Brauer M, Günther A, Pleul K, Götze M, Wachsmuth C, Meinig T, Bauer M, Witte OW, Rahmel A.

Anaesthesist. 2019 Jan;68(1):22-29. doi: 10.1007/s00101-018-0510-x. Epub 2018 Nov 16. German.

PMID:
30446808
36.

Long-term safety of pirfenidone: results of the prospective, observational PASSPORT study.

Cottin V, Koschel D, Günther A, Albera C, Azuma A, Sköld CM, Tomassetti S, Hormel P, Stauffer JL, Strombom I, Kirchgaessler KU, Maher TM.

ERJ Open Res. 2018 Oct 19;4(4). pii: 00084-2018. doi: 10.1183/23120541.00084-2018. eCollection 2018 Oct.

37.

A phase 1 healthy male volunteer single escalating dose study of the pharmacokinetics and pharmacodynamics of risdiplam (RG7916, RO7034067), a SMN2 splicing modifier.

Sturm S, Günther A, Jaber B, Jordan P, Al Kotbi N, Parkar N, Cleary Y, Frances N, Bergauer T, Heinig K, Kletzl H, Marquet A, Ratni H, Poirier A, Müller L, Czech C, Khwaja O.

Br J Clin Pharmacol. 2019 Jan;85(1):181-193. doi: 10.1111/bcp.13786. Epub 2018 Nov 16.

PMID:
30302786
38.

Acute Stroke Treatment by Surgical Recanalization of Extracranial Internal Carotid Artery Occlusion: A Single Center Experience.

Schubert J, Witte OW, Settmacher U, Mayer TE, Günther A, Zanow J, Klingner CM.

Vasc Endovascular Surg. 2019 Jan;53(1):21-27. doi: 10.1177/1538574418800131. Epub 2018 Oct 9.

PMID:
30301430
39.

The cost-effectiveness of a 20% price discount on fruit, vegetables, diet drinks and water, trialled in remote Australia to improve Indigenous health.

Magnus A, Cobiac L, Brimblecombe J, Chatfield M, Gunther A, Ferguson M, Moodie M.

PLoS One. 2018 Sep 27;13(9):e0204005. doi: 10.1371/journal.pone.0204005. eCollection 2018.

40.

Dorsal BNST α2A-Adrenergic Receptors Produce HCN-Dependent Excitatory Actions That Initiate Anxiogenic Behaviors.

Harris NA, Isaac AT, Günther A, Merkel K, Melchior J, Xu M, Eguakun E, Perez R, Nabit BP, Flavin S, Gilsbach R, Shonesy B, Hein L, Abel T, Baumann A, Matthews R, Centanni SW, Winder DG.

J Neurosci. 2018 Oct 17;38(42):8922-8942. doi: 10.1523/JNEUROSCI.0963-18.2018. Epub 2018 Aug 27.

41.

Data Discovery for Integration of Heterogeneous Medical Datasets in the German Center for Lung Research (DZL).

Majeed RW, Stöhr MR, Ruppert C, Günther A.

Stud Health Technol Inform. 2018;253:65-69.

PMID:
30147042
42.

Metadata Import from RDF to i2b2.

Stöhr MR, Majeed RW, Günther A.

Stud Health Technol Inform. 2018;253:40-44.

PMID:
30147037
43.

Effect of alkali ions on optical properties of flavins: vibronic spectra of cryogenic M+lumichrome ions (M = Li-Cs) in the gas phase.

Nieto P, Müller D, Sheldrick A, Günther A, Miyazaki M, Dopfer O.

Phys Chem Chem Phys. 2018 Aug 29;20(34):22148-22158. doi: 10.1039/c8cp03950j.

PMID:
30116801
44.

The FLORA study: presenting a novel IPF trial design.

Crestani B, Günther A.

Lancet Respir Med. 2018 Aug;6(8):572-573. doi: 10.1016/S2213-2600(18)30269-8. Epub 2018 Jun 27. No abstract available.

PMID:
29960880
45.

The Earth's Magnetic Field and Visual Landmarks Steer Migratory Flight Behavior in the Nocturnal Australian Bogong Moth.

Dreyer D, Frost B, Mouritsen H, Günther A, Green K, Whitehouse M, Johnsen S, Heinze S, Warrant E.

Curr Biol. 2018 Jul 9;28(13):2160-2166.e5. doi: 10.1016/j.cub.2018.05.030. Epub 2018 Jun 21.

46.

Is the fibroblast growth factor signaling pathway a victim of receptor tyrosine kinase inhibition in pulmonary parenchymal and vascular remodeling?

El Agha E, Schwind F, Ruppert C, Günther A, Bellusci S, Schermuly RT, Kosanovic D.

Am J Physiol Lung Cell Mol Physiol. 2018 Aug 1;315(2):L248-L252. doi: 10.1152/ajplung.00140.2018. Epub 2018 May 3.

47.

Determination of the hydrogen-bond network and the ferrimagnetic structure of a rockbridgeite-type compound, [Formula: see text].

Röska B, Park SH, Behal D, Hess KU, Günther A, Benka G, Pfleiderer C, Hoelzel M, Kimura T.

J Phys Condens Matter. 2018 Jun 13;30(23):235401. doi: 10.1088/1361-648X/aac0cd. Epub 2018 Apr 27.

PMID:
29701605
48.

Using RDF and Git to Realize a Collaborative Metadata Repository.

Stöhr MR, Majeed RW, Günther A.

Stud Health Technol Inform. 2018;247:556-560.

PMID:
29678022
49.

Handheld skin printer: in situ formation of planar biomaterials and tissues.

Hakimi N, Cheng R, Leng L, Sotoudehfar M, Ba PQ, Bakhtyar N, Amini-Nik S, Jeschke MG, Günther A.

Lab Chip. 2018 May 15;18(10):1440-1451. doi: 10.1039/c7lc01236e.

50.

Management of therapeutic anticoagulation in patients with intracerebral haemorrhage and mechanical heart valves.

Kuramatsu JB, Sembill JA, Gerner ST, Sprügel MI, Hagen M, Roeder SS, Endres M, Haeusler KG, Sobesky J, Schurig J, Zweynert S, Bauer M, Vajkoczy P, Ringleb PA, Purrucker J, Rizos T, Volkmann J, Müllges W, Kraft P, Schubert AL, Erbguth F, Nueckel M, Schellinger PD, Glahn J, Knappe UJ, Fink GR, Dohmen C, Stetefeld H, Fisse AL, Minnerup J, Hagemann G, Rakers F, Reichmann H, Schneider H, Wöpking S, Ludolph AC, Stösser S, Neugebauer H, Röther J, Michels P, Schwarz M, Reimann G, Bäzner H, Schwert H, Claßen J, Michalski D, Grau A, Palm F, Urbanek C, Wöhrle JC, Alshammari F, Horn M, Bahner D, Witte OW, Günther A, Hamann GF, Lücking H, Dörfler A, Achenbach S, Schwab S, Huttner HB.

Eur Heart J. 2018 May 14;39(19):1709-1723. doi: 10.1093/eurheartj/ehy056.

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