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Items: 20

1.

Neuronal network dysfunction in a model for Kleefstra syndrome mediated by enhanced NMDAR signaling.

Frega M, Linda K, Keller JM, Gümüş-Akay G, Mossink B, van Rhijn JR, Negwer M, Klein Gunnewiek T, Foreman K, Kompier N, Schoenmaker C, van den Akker W, van der Werf I, Oudakker A, Zhou H, Kleefstra T, Schubert D, van Bokhoven H, Nadif Kasri N.

Nat Commun. 2019 Oct 30;10(1):4928. doi: 10.1038/s41467-019-12947-3.

2.

White Noise Speech Illusions: A Trait-Dependent Risk Marker for Psychotic Disorder?

Schepers E, Lousberg R, Guloksuz S, Pries LK, Delespaul P, Kenis G, Luykx JJ, Lin BD, Richards AL, Akdede B, Binbay T, Altınyazar V, Yalınçetin B, Gümüş-Akay G, Cihan B, Soygür H, Ulaş H, Şahin Cankurtaran E, Ulusoy Kaymak S, Mihaljevic MM, Andric Petrovic S, Mirjanic T, Bernardo M, Cabrera B, Bobes J, Saiz PA, García-Portilla MP, Sanjuan J, Aguilar EJ, Luis Santos J, Jiménez-López E, Arrojo M, Carracedo A, López G, González-Peñas J, Parellada M, Maric NP, Atbaşoğlu C, Ucok A, Alptekin K, Can Saka M, Arango C, Rutten BPF, van Os J.

Front Psychiatry. 2019 Sep 25;10:676. doi: 10.3389/fpsyt.2019.00676. eCollection 2019.

3.

Estimating Exposome Score for Schizophrenia Using Predictive Modeling Approach in Two Independent Samples: The Results From the EUGEI Study.

Pries LK, Lage-Castellanos A, Delespaul P, Kenis G, Luykx JJ, Lin BD, Richards AL, Akdede B, Binbay T, Altinyazar V, Yalinçetin B, Gümüş-Akay G, Cihan B, Soygür H, Ulaş H, Cankurtaran EŞ, Kaymak SU, Mihaljevic MM, Petrovic SA, Mirjanic T, Bernardo M, Cabrera B, Bobes J, Saiz PA, García-Portilla MP, Sanjuan J, Aguilar EJ, Santos JL, Jiménez-López E, Arrojo M, Carracedo A, López G, González-Peñas J, Parellada M, Maric NP, Atbaşoğlu C, Ucok A, Alptekin K, Saka MC; Genetic Risk and Outcome of Psychosis (GROUP) investigators, Arango C, O'Donovan M, Rutten BPF, van Os J, Guloksuz S.

Schizophr Bull. 2019 Sep 11;45(5):960-965. doi: 10.1093/schbul/sbz054.

PMID:
31508804
4.

Replicated evidence that endophenotypic expression of schizophrenia polygenic risk is greater in healthy siblings of patients compared to controls, suggesting gene-environment interaction. The EUGEI study.

van Os J, Pries LK, Delespaul P, Kenis G, Luykx JJ, Lin BD, Richards AL, Akdede B, Binbay T, Altınyazar V, Yalınçetin B, Gümüş-Akay G, Cihan B, Soygür H, Ulaş H, Cankurtaran EŞ, Kaymak SU, Mihaljevic MM, Petrovic SA, Mirjanic T, Bernardo M, Cabrera B, Bobes J, Saiz PA, García-Portilla MP, Sanjuan J, Aguilar EJ, Santos JL, Jiménez-López E, Arrojo M, Carracedo A, López G, González-Peñas J, Parellada M, Maric NP, Atbaşoğlu C, Ucok A, Alptekin K, Saka MC; Genetic Risk and Outcome Investigators (GROUP), Arango C, O'Donovan M, Rutten BPF, Guloksuz S.

Psychol Med. 2019 Aug 15:1-14. doi: 10.1017/S003329171900196X. [Epub ahead of print]

PMID:
31414981
5.

Examining the independent and joint effects of molecular genetic liability and environmental exposures in schizophrenia: results from the EUGEI study.

Guloksuz S, Pries LK, Delespaul P, Kenis G, Luykx JJ, Lin BD, Richards AL, Akdede B, Binbay T, Altınyazar V, Yalınçetin B, Gümüş-Akay G, Cihan B, Soygür H, Ulaş H, Cankurtaran E, Kaymak SU, Mihaljevic MM, Petrovic SA, Mirjanic T, Bernardo M, Cabrera B, Bobes J, Saiz PA, García-Portilla MP, Sanjuan J, Aguilar EJ, Santos JL, Jiménez-López E, Arrojo M, Carracedo A, López G, González-Peñas J, Parellada M, Maric NP, Atbaşog Lu C, Ucok A, Alptekin K, Saka MC; Genetic Risk and Outcome of Psychosis (GROUP) investigators, Arango C, O'Donovan M, Rutten BPF, van Os J.

World Psychiatry. 2019 Jun;18(2):173-182. doi: 10.1002/wps.20629.

6.

Psychometric liability to psychosis and childhood adversities are associated with shorter telomere length: A study on schizophrenia patients, unaffected siblings, and non-clinical controls.

Çevik B, Mançe-Çalışır Ö, Atbaşoğlu EC, Saka MC, Alptekin K, Üçok A, Sırmatel B, Gülöksüz S, Tükün A, van Os J, Gümüş-Akay G.

J Psychiatr Res. 2019 Apr;111:169-185. doi: 10.1016/j.jpsychires.2019.01.022. Epub 2019 Feb 8.

PMID:
30776705
7.

Higher schizotypy predicts better metabolic profile in unaffected siblings of patients with schizophrenia.

Atbasoglu EC, Gumus-Akay G, Guloksuz S, Saka MC, Ucok A, Alptekin K, Gullu S, van Os J.

Psychopharmacology (Berl). 2018 Apr;235(4):1029-1039. doi: 10.1007/s00213-017-4818-z. Epub 2018 Jan 6.

PMID:
29306964
8.

Diagnostic and prognostic significance of glypican 5 and glypican 6 gene expression levels in gastric adenocarcinoma.

Dinccelik-Aslan M, Gumus-Akay G, Elhan AH, Unal E, Tukun A.

Mol Clin Oncol. 2015 May;3(3):584-590. Epub 2015 Jan 19.

9.

Identifying gene-environment interactions in schizophrenia: contemporary challenges for integrated, large-scale investigations.

European Network of National Networks studying Gene-Environment Interactions in Schizophrenia (EU-GEI), van Os J, Rutten BP, Myin-Germeys I, Delespaul P, Viechtbauer W, van Zelst C, Bruggeman R, Reininghaus U, Morgan C, Murray RM, Di Forti M, McGuire P, Valmaggia LR, Kempton MJ, Gayer-Anderson C, Hubbard K, Beards S, Stilo SA, Onyejiaka A, Bourque F, Modinos G, Tognin S, Calem M, O'Donovan MC, Owen MJ, Holmans P, Williams N, Craddock N, Richards A, Humphreys I, Meyer-Lindenberg A, Leweke FM, Tost H, Akdeniz C, Rohleder C, Bumb JM, Schwarz E, Alptekin K, Üçok A, Saka MC, Atbaşoğlu EC, Gülöksüz S, Gumus-Akay G, Cihan B, Karadağ H, Soygür H, Cankurtaran EŞ, Ulusoy S, Akdede B, Binbay T, Ayer A, Noyan H, Karadayı G, Akturan E, Ulaş H, Arango C, Parellada M, Bernardo M, Sanjuán J, Bobes J, Arrojo M, Santos JL, Cuadrado P, Rodríguez Solano JJ, Carracedo A, García Bernardo E, Roldán L, López G, Cabrera B, Cruz S, Díaz Mesa EM, Pouso M, Jiménez E, Sánchez T, Rapado M, González E, Martínez C, Sánchez E, Olmeda MS, de Haan L, Velthorst E, van der Gaag M, Selten JP, van Dam D, van der Ven E, van der Meer F, Messchaert E, Kraan T, Burger N, Leboyer M, Szoke A, Schürhoff F, Llorca PM, Jamain S, Tortelli A, Frijda F, Vilain J, Galliot AM, Baudin G, Ferchiou A, Richard JR, Bulzacka E, Charpeaud T, Tronche AM, De Hert M, van Winkel R, Decoster J, Derom C, Thiery E, Stefanis NC, Sachs G, Aschauer H, Lasser I, Winklbaur B, Schlögelhofer M, Riecher-Rössler A, Borgwardt S, Walter A, Harrisberger F, Smieskova R, Rapp C, Ittig S, Soguel-dit-Piquard F, Studerus E, Klosterkötter J, Ruhrmann S, Paruch J, Julkowski D, Hilboll D, Sham PC, Cherny SS, Chen EY, Campbell DD, Li M, Romeo-Casabona CM, Emaldi Cirión A, Urruela Mora A, Jones P, Kirkbride J, Cannon M, Rujescu D, Tarricone I, Berardi D, Bonora E, Seri M, Marcacci T, Chiri L, Chierzi F, Storbini V, Braca M, Minenna MG, Donegani I, Fioritti A, La Barbera D, La Cascia CE, Mulè A, Sideli L, Sartorio R, Ferraro L, Tripoli G, Seminerio F, Marinaro AM, McGorry P, Nelson B, Amminger GP, Pantelis C, Menezes PR, Del-Ben CM, Gallo Tenan SH, Shuhama R, Ruggeri M, Tosato S, Lasalvia A, Bonetto C, Ira E, Nordentoft M, Krebs MO, Barrantes-Vidal N, Cristóbal P, Kwapil TR, Brietzke E, Bressan RA, Gadelha A, Maric NP, Andric S, Mihaljevic M, Mirjanic T.

Schizophr Bull. 2014 Jul;40(4):729-36. doi: 10.1093/schbul/sbu069. Epub 2014 May 24. Review.

10.

Association analysis of three ABCB1 (MDR1) gene variants (C1236T, G2677A/T and C3435T) and their genotype/haplotype combinations with the familial Mediterranean fever.

Rustemoglu A, Gumus-Akay G, Karakus N, Yigit S, Sahin S, Tasliyurt T.

Xenobiotica. 2014 Oct;44(10):933-40. doi: 10.3109/00498254.2014.915071. Epub 2014 Apr 28.

PMID:
24773260
11.

[Fragile X premutation in adult psychiatry: four cases and overview of clinical presentation].

Atbaşoğlu EC, Sakarya D, Gümüş Akay G, Sakarya A, Tükün A.

Turk Psikiyatri Derg. 2013 Spring;24(1):63-7. Turkish.

12.

MDR1 gene polymorphisms may be associated with Behçet's disease and its colchicum treatment response.

Rustemoglu A, Gül Ü, Gümüş-Akay G, Gönül M, Yiğit S, Bozkurt N, Karadağ A, Pişkin E, Sunguroğlu A, Kadıkıran A.

Gene. 2012 Sep 1;505(2):333-9. doi: 10.1016/j.gene.2012.05.040. Epub 2012 Jun 15.

PMID:
22705826
13.

Potential genotoxic effect of 186Re-HEDP on human lymphocyte cells: in-vitro evaluation with micronucleus-FISH analysis.

Ozkal-Baydin P, Gümüş-Akay G, Varol N, Rüstemoğlu A, Köroğlu R, Yüksel S, Küçük O, Aras G, Ibiş E, Sunguroğlu A.

Nucl Med Commun. 2012 Apr;33(4):415-21. doi: 10.1097/MNM.0b013e3283505188.

PMID:
22273639
14.

Analysis of common MDR1 (ABCB1) gene C1236T and C3435T polymorphisms in Turkish patients with familial Mediterranean fever.

Rüstemoglu A, Gumus-Akay G, Yigit S, Tasliyurt T.

Genet Mol Res. 2011 Dec 14;10(4):3411-20. doi: 10.4238/2011.December.14.7.

15.

Endothelial nitric oxide synthase gene polymorphism in gastric cancer.

Tecder Ünal M, Karabulut HG, Gümüş-Akay G, Dölen Y, Elhan A, Tükün A, Ünal AE.

Turk J Gastroenterol. 2010 Dec;21(4):338-44.

16.

DNA copy number changes in gastric adenocarcinomas: high resolution-comparative genomic hybridization study in Turkey.

Gümüs-Akay G, Unal AE, Elhan AH, Bayar S, Karadayt K, Sunguroglu A, Kadikiran A, Tükün A.

Arch Med Res. 2009 Oct;40(7):551-60. doi: 10.1016/j.arcmed.2009.07.004.

PMID:
20082868
17.

Haplotype-based analysis of MDR1/ABCB1 gene polymorphisms in a Turkish population.

Gümüş-Akay G, Rüstemoğlu A, Karadağ A, Sunguroğlu A.

DNA Cell Biol. 2010 Feb;29(2):83-90. doi: 10.1089/dna.2009.0953.

PMID:
20025534
18.

Effects of genomic imbalances on telomerase activity in gastric cancer: clues to telomerase regulation.

Gümüş-Akay G, Elhan AH, Unal AE, Demirkazik A, Sunguroğlu A, Tükün A.

Oncol Res. 2009;17(10):455-62.

PMID:
19725225
19.

Genotype and allele frequencies of MDR1 gene C1236T polymorphism in a Turkish population.

Gümüş-Akay G, Rüstemoğlu A, Karadağ A, Sunguroğlu A.

Genet Mol Res. 2008 Oct 28;7(4):1193-9.

20.

Telomerase activity could be used as a marker for neoplastic transformation in gastric adenocarcinoma: but it does not have a prognostic significance.

Gümüş-Akay G, Unal AE, Bayar S, Karadayi K, Elhan AH, Sunguroĝlu A, Tükün A.

Genet Mol Res. 2007 Feb 15;6(1):41-9.

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