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Items: 28

1.

Notch ligand delta-like 4 blockade attenuates atherosclerosis and metabolic disorders.

Fukuda D, Aikawa E, Swirski FK, Novobrantseva TI, Kotelianski V, Gorgun CZ, Chudnovskiy A, Yamazaki H, Croce K, Weissleder R, Aster JC, Hotamisligil GS, Yagita H, Aikawa M.

Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):E1868-77. doi: 10.1073/pnas.1116889109. Epub 2012 Jun 13.

2.

Macrophage Mal1 deficiency suppresses atherosclerosis in low-density lipoprotein receptor-null mice by activating peroxisome proliferator-activated receptor-γ-regulated genes.

Babaev VR, Runner RP, Fan D, Ding L, Zhang Y, Tao H, Erbay E, Görgün CZ, Fazio S, Hotamisligil GS, Linton MF.

Arterioscler Thromb Vasc Biol. 2011 Jun;31(6):1283-90. doi: 10.1161/ATVBAHA.111.225839. Epub 2011 Apr 7.

3.

Double-stranded RNA-dependent protein kinase links pathogen sensing with stress and metabolic homeostasis.

Nakamura T, Furuhashi M, Li P, Cao H, Tuncman G, Sonenberg N, Gorgun CZ, Hotamisligil GS.

Cell. 2010 Feb 5;140(3):338-48. doi: 10.1016/j.cell.2010.01.001.

4.

Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice.

Liu J, Divoux A, Sun J, Zhang J, Clément K, Glickman JN, Sukhova GK, Wolters PJ, Du J, Gorgun CZ, Doria A, Libby P, Blumberg RS, Kahn BB, Hotamisligil GS, Shi GP.

Nat Med. 2009 Aug;15(8):940-5. doi: 10.1038/nm.1994. Epub 2009 Jul 26.

5.

Adipocyte/macrophage fatty acid-binding proteins contribute to metabolic deterioration through actions in both macrophages and adipocytes in mice.

Furuhashi M, Fucho R, Görgün CZ, Tuncman G, Cao H, Hotamisligil GS.

J Clin Invest. 2008 Jul;118(7):2640-50. doi: 10.1172/JCI34750.

6.

Deficiency of fatty acid-binding proteins in mice confers protection from development of experimental autoimmune encephalomyelitis.

Reynolds JM, Liu Q, Brittingham KC, Liu Y, Gruenthal M, Gorgun CZ, Hotamisligil GS, Stout RD, Suttles J.

J Immunol. 2007 Jul 1;179(1):313-21.

7.

Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2.

Furuhashi M, Tuncman G, Görgün CZ, Makowski L, Atsumi G, Vaillancourt E, Kono K, Babaev VR, Fazio S, Linton MF, Sulsky R, Robl JA, Parker RA, Hotamisligil GS.

Nature. 2007 Jun 21;447(7147):959-65. Epub 2007 Jun 6.

8.

Coordinated regulation of nutrient and inflammatory responses by STAMP2 is essential for metabolic homeostasis.

Wellen KE, Fucho R, Gregor MF, Furuhashi M, Morgan C, Lindstad T, Vaillancourt E, Gorgun CZ, Saatcioglu F, Hotamisligil GS.

Cell. 2007 May 4;129(3):537-48.

9.

Tumor necrosis factor alpha-induced skeletal muscle insulin resistance involves suppression of AMP-kinase signaling.

Steinberg GR, Michell BJ, van Denderen BJ, Watt MJ, Carey AL, Fam BC, Andrikopoulos S, Proietto J, Görgün CZ, Carling D, Hotamisligil GS, Febbraio MA, Kay TW, Kemp BE.

Cell Metab. 2006 Dec;4(6):465-74.

10.

Regulation of dendritic cell function and T cell priming by the fatty acid-binding protein AP2.

Rolph MS, Young TR, Shum BO, Gorgun CZ, Schmitz-Peiffer C, Ramshaw IA, Hotamisligil GS, Mackay CR.

J Immunol. 2006 Dec 1;177(11):7794-801.

11.

Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes.

Ozcan U, Yilmaz E, Ozcan L, Furuhashi M, Vaillancourt E, Smith RO, Görgün CZ, Hotamisligil GS.

Science. 2006 Aug 25;313(5790):1137-40.

12.

Neuronal PTP1B regulates body weight, adiposity and leptin action.

Bence KK, Delibegovic M, Xue B, Gorgun CZ, Hotamisligil GS, Neel BG, Kahn BB.

Nat Med. 2006 Aug;12(8):917-24. Epub 2006 Jul 16. Erratum in: Nat Med. 2010 Feb;16(2):237.

PMID:
16845389
13.

The adipocyte fatty acid-binding protein aP2 is required in allergic airway inflammation.

Shum BO, Mackay CR, Gorgun CZ, Frost MJ, Kumar RK, Hotamisligil GS, Rolph MS.

J Clin Invest. 2006 Aug;116(8):2183-2192.

14.

Regulation of metabolic responses by adipocyte/macrophage Fatty Acid-binding proteins in leptin-deficient mice.

Cao H, Maeda K, Gorgun CZ, Kim HJ, Park SY, Shulman GI, Kim JK, Hotamisligil GS.

Diabetes. 2006 Jul;55(7):1915-22.

15.

Adipocyte/macrophage fatty acid binding proteins control integrated metabolic responses in obesity and diabetes.

Maeda K, Cao H, Kono K, Gorgun CZ, Furuhashi M, Uysal KT, Cao Q, Atsumi G, Malone H, Krishnan B, Minokoshi Y, Kahn BB, Parker RA, Hotamisligil GS.

Cell Metab. 2005 Feb;1(2):107-19.

16.

Role of the fatty acid binding protein mal1 in obesity and insulin resistance.

Maeda K, Uysal KT, Makowski L, Görgün CZ, Atsumi G, Parker RA, Brüning J, Hertzel AV, Bernlohr DA, Hotamisligil GS.

Diabetes. 2003 Feb;52(2):300-7.

17.

A central role for JNK in obesity and insulin resistance.

Hirosumi J, Tuncman G, Chang L, Görgün CZ, Uysal KT, Maeda K, Karin M, Hotamisligil GS.

Nature. 2002 Nov 21;420(6913):333-6.

PMID:
12447443
18.

Obesity modulates the expression of haptoglobin in the white adipose tissue via TNFalpha.

Chiellini C, Bertacca A, Novelli SE, Görgün CZ, Ciccarone A, Giordano A, Xu H, Soukas A, Costa M, Gandini D, Dimitri R, Bottone P, Cecchetti P, Pardini E, Perego L, Navalesi R, Folli F, Benzi L, Cinti S, Friedman JM, Hotamisligil GS, Maffei M.

J Cell Physiol. 2002 Feb;190(2):251-8.

PMID:
11807829
19.

Adipose tissue resistin expression is severely suppressed in obesity and stimulated by peroxisome proliferator-activated receptor gamma agonists.

Way JM, Görgün CZ, Tong Q, Uysal KT, Brown KK, Harrington WW, Oliver WR Jr, Willson TM, Kliewer SA, Hotamisligil GS.

J Biol Chem. 2001 Jul 13;276(28):25651-3. Epub 2001 May 23.

20.

Biological-time-dependent differences in effect of verapamil on rat aorta and influence of endothelium.

Güney HZ, Uluoğlu C, Hodoğlugil U, Görgün CZ, Yamanoğlu TM, Abacioğlu N, Zengil H.

Chronobiol Int. 1999 Nov;16(6):779-87.

PMID:
10584178
21.

Circadian-rhythm-dependent effects of L-NG-nitroarginine methyl ester (L-NAME) on morphine-induced analgesia.

Güney HZ, Görgün CZ, Tunçtan B, Uludağ O, Hodoğlugil U, Abacioğlu N, Zengil H.

Chronobiol Int. 1998 May;15(3):283-9.

PMID:
9653581
22.

In vitro susceptibility rhythms. II. Biological-time-dependent differences in effect of beta 1- and beta 2-adrenergic agonists of rat aorta and influence of endothelium.

Güney HZ, Hodoğlugil U, Uluoğlu C, Görgün CZ, Ercan ZS, Abacioğlu N, Zengil H.

Chronobiol Int. 1998 Mar;15(2):159-72.

PMID:
9562920
23.

In vitro evidence of tissue susceptibility rhythms. I. Temporal variation in effect of potassium chloride and phenylephrine on rat aorta.

Görgün CZ, Keskil ZA, Hodoglugil U, Ercan ZS, Abacioglu N, Zengil H.

Chronobiol Int. 1998 Jan;15(1):39-48.

PMID:
9493713
24.

Twenty-four-hour variations in the effect of nitrodilators in rat aorta: lack of influence of the endothelium.

Hodoglugil U, Uluoglu C, Güney HZ, Görgün CZ, Ercan ZS, Abacioglu N, Zengil H.

J Pharm Pharmacol. 1997 Nov;49(11):1102-8.

PMID:
9401946
26.

Effects of auro-detoxin treatment on vascular responses in mouse aorta.

Güney HZ, Görgün CZ, Hodoğlugil U, Zengil H.

Gen Pharmacol. 1997 Aug;29(2):261-4.

PMID:
9251910
27.

Twenty-four-hour variations in the sensitivity of rat aorta to vasoactive agents.

Keskil Z, Görgün CZ, Hodoğlugil U, Zengil H.

Chronobiol Int. 1996 Dec;13(6):465-75.

PMID:
8974192
28.

Temporal variation in the interaction between calcium channel blockers and morphine-induced analgesia.

Hodoğluğil U, Güney HZ, Savran B, Güzey C, Görgün CZ, Zengil H.

Chronobiol Int. 1996 Aug;13(3):227-34.

PMID:
8874985

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