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Items: 11

1.

IKBKE inhibits TSC1 to activate the mTOR/S6K pathway for oncogenic transformation.

Göktuna Sİ.

Turk J Biol. 2018 Aug 9;42(4):268-278. doi: 10.3906/biy-1801-57. eCollection 2018.

2.

IKKs and tumor cell plasticity.

Göktuna SI, Diamanti MA, Chau TL.

FEBS J. 2018 Jun;285(12):2161-2181. doi: 10.1111/febs.14444. Epub 2018 Apr 17. Review.

3.

Correction: Elp3 drives Wnt-dependent tumor initiation and regeneration in the intestine.

Ladang A, Rapino F, Heukamp LC, Tharun L, Shostak K, Hermand D, Delaunay S, Klevernic I, Jiang Z, Jacques N, Jamart D, Migeot V, Florin A, Göktuna S, Malgrange B, Sansom OJ, Nguyen L, Büttner R, Close P, Chariot A.

J Exp Med. 2017 Apr 3;214(4):1199. doi: 10.1084/jem.2014228803082017c. Epub 2017 Mar 10. No abstract available.

4.

The Prosurvival IKK-Related Kinase IKKε Integrates LPS and IL17A Signaling Cascades to Promote Wnt-Dependent Tumor Development in the Intestine.

Göktuna SI, Shostak K, Chau TL, Heukamp LC, Hennuy B, Duong HQ, Ladang A, Close P, Klevernic I, Olivier F, Florin A, Ehx G, Baron F, Vandereyken M, Rahmouni S, Vereecke L, van Loo G, Büttner R, Greten FR, Chariot A.

Cancer Res. 2016 May 1;76(9):2587-99. doi: 10.1158/0008-5472.CAN-15-1473. Epub 2016 Mar 15.

5.

Elp3 drives Wnt-dependent tumor initiation and regeneration in the intestine.

Ladang A, Rapino F, Heukamp LC, Tharun L, Shostak K, Hermand D, Delaunay S, Klevernic I, Jiang Z, Jacques N, Jamart D, Migeot V, Florin A, Göktuna S, Malgrange B, Sansom OJ, Nguyen L, Büttner R, Close P, Chariot A.

J Exp Med. 2015 Nov 16;212(12):2057-75. doi: 10.1084/jem.20142288. Epub 2015 Nov 2. Erratum in: J Exp Med. 2017 Apr 3;214(4):1199.

6.

A role for APPL1 in TLR3/4-dependent TBK1 and IKKε activation in macrophages.

Chau TL, Göktuna SI, Rammal A, Casanova T, Duong HQ, Gatot JS, Close P, Dejardin E, Desmecht D, Shostak K, Chariot A.

J Immunol. 2015 Apr 15;194(8):3970-83. doi: 10.4049/jimmunol.1401614. Epub 2015 Mar 16.

7.

NF-κB-induced KIAA1199 promotes survival through EGFR signalling.

Shostak K, Zhang X, Hubert P, Göktuna SI, Jiang Z, Klevernic I, Hildebrand J, Roncarati P, Hennuy B, Ladang A, Somja J, Gothot A, Close P, Delvenne P, Chariot A.

Nat Commun. 2014 Nov 4;5:5232. doi: 10.1038/ncomms6232.

8.

IKKα promotes intestinal tumorigenesis by limiting recruitment of M1-like polarized myeloid cells.

Göktuna SI, Canli O, Bollrath J, Fingerle AA, Horst D, Diamanti MA, Pallangyo C, Bennecke M, Nebelsiek T, Mankan AK, Lang R, Artis D, Hu Y, Patzelt T, Ruland J, Kirchner T, Taketo MM, Chariot A, Arkan MC, Greten FR.

Cell Rep. 2014 Jun 26;7(6):1914-25. doi: 10.1016/j.celrep.2014.05.006. Epub 2014 May 29.

9.

MDM2 restrains estrogen-mediated AKT activation by promoting TBK1-dependent HPIP degradation.

Shostak K, Patrascu F, Göktuna SI, Close P, Borgs L, Nguyen L, Olivier F, Rammal A, Brinkhaus H, Bentires-Alj M, Marine JC, Chariot A.

Cell Death Differ. 2014 May;21(5):811-24. doi: 10.1038/cdd.2014.2. Epub 2014 Jan 31.

10.

Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties.

Schwitalla S, Fingerle AA, Cammareri P, Nebelsiek T, Göktuna SI, Ziegler PK, Canli O, Heijmans J, Huels DJ, Moreaux G, Rupec RA, Gerhard M, Schmid R, Barker N, Clevers H, Lang R, Neumann J, Kirchner T, Taketo MM, van den Brink GR, Sansom OJ, Arkan MC, Greten FR.

Cell. 2013 Jan 17;152(1-2):25-38. doi: 10.1016/j.cell.2012.12.012. Epub 2012 Dec 27.

11.

NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta.

Greten FR, Arkan MC, Bollrath J, Hsu LC, Goode J, Miething C, Göktuna SI, Neuenhahn M, Fierer J, Paxian S, Van Rooijen N, Xu Y, O'Cain T, Jaffee BB, Busch DH, Duyster J, Schmid RM, Eckmann L, Karin M.

Cell. 2007 Sep 7;130(5):918-31.

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