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Items: 16

1.

Revealing Adenosine A2A-Dopamine D2 Receptor Heteromers in Parkinson's Disease Post-Mortem Brain through a New AlphaScreen-Based Assay.

Fernández-Dueñas V, Gómez-Soler M, Valle-León M, Watanabe M, Ferrer I, Ciruela F.

Int J Mol Sci. 2019 Jul 23;20(14). pii: E3600. doi: 10.3390/ijms20143600.

2.

Engineering nanomolar peptide ligands that differentially modulate EphA2 receptor signaling.

Gomez-Soler M, Petersen Gehring M, Lechtenberg BC, Zapata-Mercado E, Hristova K, Pasquale EB.

J Biol Chem. 2019 May 31;294(22):8791-8805. doi: 10.1074/jbc.RA119.008213. Epub 2019 Apr 23.

PMID:
31015204
3.

Triglyceride Form of Docosahexaenoic Acid Mediates Neuroprotection in Experimental Parkinsonism.

Gómez-Soler M, Cordobilla B, Morató X, Fernández-Dueñas V, Domingo JC, Ciruela F.

Front Neurosci. 2018 Aug 28;12:604. doi: 10.3389/fnins.2018.00604. eCollection 2018.

4.

Antipsychotic-Like Efficacy of Dopamine D2 Receptor-Biased Ligands is Dependent on Adenosine A2A Receptor Expression.

Sahlholm K, Gómez-Soler M, Valle-León M, López-Cano M, Taura JJ, Ciruela F, Fernández-Dueñas V.

Mol Neurobiol. 2018 Jun;55(6):4952-4958. doi: 10.1007/s12035-017-0696-y. Epub 2017 Aug 5.

PMID:
28779351
5.

Membrane omega-3 fatty acids modulate the oligomerisation kinetics of adenosine A2A and dopamine D2 receptors.

Guixà-González R, Javanainen M, Gómez-Soler M, Cordobilla B, Domingo JC, Sanz F, Pastor M, Ciruela F, Martinez-Seara H, Selent J.

Sci Rep. 2016 Jan 22;6:19839. doi: 10.1038/srep19839.

6.

Adenosine A1 receptor activation modulates N-methyl-d-aspartate (NMDA) preconditioning phenotype in the brain.

Constantino LC, Pamplona FA, Matheus FC, Ludka FK, Gomez-Soler M, Ciruela F, Boeck CR, Prediger RD, Tasca CI.

Behav Brain Res. 2015 Apr 1;282:103-10. doi: 10.1016/j.bbr.2014.12.056. Epub 2014 Dec 31.

PMID:
25557798
7.

Untangling dopamine-adenosine receptor-receptor assembly in experimental parkinsonism in rats.

Fernández-Dueñas V, Taura JJ, Cottet M, Gómez-Soler M, López-Cano M, Ledent C, Watanabe M, Trinquet E, Pin JP, Luján R, Durroux T, Ciruela F.

Dis Model Mech. 2015 Jan;8(1):57-63. doi: 10.1242/dmm.018143. Epub 2014 Nov 14.

8.

Coassembly and coupling of SK2 channels and mGlu5 receptors.

García-Negredo G, Soto D, Llorente J, Morató X, Galenkamp KM, Gómez-Soler M, Fernández-Dueñas V, Watanabe M, Adelman JP, Shigemoto R, Fukazawa Y, Luján R, Ciruela F.

J Neurosci. 2014 Oct 29;34(44):14793-802. doi: 10.1523/JNEUROSCI.2038-14.2014.

9.

Uncovering caffeine's adenosine A2A receptor inverse agonism in experimental parkinsonism.

Fernández-Dueñas V, Gómez-Soler M, López-Cano M, Taura JJ, Ledent C, Watanabe M, Jacobson KA, Vilardaga JP, Ciruela F.

ACS Chem Biol. 2014 Nov 21;9(11):2496-501. doi: 10.1021/cb5005383. Epub 2014 Oct 2.

10.

Deciphering G protein-coupled receptor biology with fluorescence-based methods.

Ciruela F, Vallano A, Cuffí ML, Carbonell L, Sánchez S, Arnau JM, Tasca C, Fernández-Dueñas V, Gómez-Soler M.

Curr Pharm Biotechnol. 2014;15(10):962-70. Review.

PMID:
25213309
11.

Predicting the antinociceptive efficacy of σ(1) receptor ligands by a novel receptor fluorescence resonance energy transfer (FRET) based biosensor.

Gómez-Soler M, Fernández-Dueñas V, Portillo-Salido E, Pérez P, Zamanillo D, Vela JM, Burgueño J, Ciruela F.

J Med Chem. 2014 Jan 9;57(1):238-42. doi: 10.1021/jm401529t. Epub 2013 Dec 20.

PMID:
24354313
12.

Dopamine D(2) receptor-mediated modulation of adenosine A(2A) receptor agonist binding within the A(2A)R/D(2)R oligomer framework.

Fernández-Dueñas V, Gómez-Soler M, Morató X, Núñez F, Das A, Kumar TS, Jaumà S, Jacobson KA, Ciruela F.

Neurochem Int. 2013 Jul;63(1):42-6. doi: 10.1016/j.neuint.2013.04.006. Epub 2013 Apr 23.

13.

Molecular determinants of A2AR-D2R allosterism: role of the intracellular loop 3 of the D2R.

Fernández-Dueñas V, Gómez-Soler M, Jacobson KA, Kumar ST, Fuxe K, Borroto-Escuela DO, Ciruela F.

J Neurochem. 2012 Nov;123(3):373-84. doi: 10.1111/j.1471-4159.2012.07956.x. Epub 2012 Sep 28.

14.

Agonist-specific voltage sensitivity at the dopamine D2S receptor--molecular determinants and relevance to therapeutic ligands.

Sahlholm K, Barchad-Avitzur O, Marcellino D, Gómez-Soler M, Fuxe K, Ciruela F, Arhem P.

Neuropharmacology. 2011 Oct-Nov;61(5-6):937-49. doi: 10.1016/j.neuropharm.2011.06.022. Epub 2011 Jul 5.

PMID:
21752340
15.

Adenosine receptor containing oligomers: their role in the control of dopamine and glutamate neurotransmission in the brain.

Ciruela F, Gómez-Soler M, Guidolin D, Borroto-Escuela DO, Agnati LF, Fuxe K, Fernández-Dueñas V.

Biochim Biophys Acta. 2011 May;1808(5):1245-55. doi: 10.1016/j.bbamem.2011.02.007. Epub 2011 Feb 18. Review.

16.

Characterization of the A2AR-D2R interface: focus on the role of the C-terminal tail and the transmembrane helices.

Borroto-Escuela DO, Romero-Fernandez W, Tarakanov AO, Gómez-Soler M, Corrales F, Marcellino D, Narvaez M, Frankowska M, Flajolet M, Heintz N, Agnati LF, Ciruela F, Fuxe K.

Biochem Biophys Res Commun. 2010 Nov 26;402(4):801-7. doi: 10.1016/j.bbrc.2010.10.122. Epub 2010 Oct 30.

PMID:
21040702

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