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Oral vancomycin induces sustained deep remission in adult patients with ulcerative colitis and primary sclerosing cholangitis.

de Chambrun GP, Nachury M, Funakoshi N, Gerard R, Bismuth M, Valats JC, Panaro F, Navarro F, Desreumaux P, Pariente B, Blanc P.

Eur J Gastroenterol Hepatol. 2018 Oct;30(10):1247-1252. doi: 10.1097/MEG.0000000000001223.


Mechanistic Investigations of Diarrhea Toxicity Induced by Anti-HER2/3 Combination Therapy.

Moisan A, Michielin F, Jacob W, Kronenberg S, Wilson S, Avignon B, Gérard R, Benmansour F, McIntyre C, Meneses-Lorente G, Hasmann M, Schneeweiss A, Weisser M, Adessi C.

Mol Cancer Ther. 2018 Jul;17(7):1464-1474. doi: 10.1158/1535-7163.MCT-17-1268. Epub 2018 Apr 13.


Patients with Crohn's Disease with High Body Mass Index Present More Frequent and Rapid Loss of Response to Infliximab.

Guerbau L, Gerard R, Duveau N, Staumont-Sallé D, Branche J, Maunoury V, Cattan S, Wils P, Boualit M, Libier L, Cotteau-Leroy A, Desreumaux P, Nachury M, Pariente B.

Inflamm Bowel Dis. 2017 Oct;23(10):1853-1859. doi: 10.1097/MIB.0000000000001179.


Challenges in Additive Manufacturing of Space Parts: Powder Feedstock Cross-Contamination and Its Impact on End Products.

Brandão AD, Gerard R, Gumpinger J, Beretta S, Makaya A, Pambaguian L, Ghidini T.

Materials (Basel). 2017 May 12;10(5). pii: E522. doi: 10.3390/ma10050522.


Post-operative management of perforated appendicitis: Can clinical pathways improve outcomes?

Gerard RR, Kielhorn BA, Petersen B, Mullard AJ, McCahill LE.

Am J Surg. 2018 Apr;215(4):593-598. doi: 10.1016/j.amjsurg.2017.06.003. Epub 2017 Jun 10.


Inhibition of EGF Uptake by Nephrotoxic Antisense Drugs In Vitro and Implications for Preclinical Safety Profiling.

Moisan A, Gubler M, Zhang JD, Tessier Y, Dumong Erichsen K, Sewing S, Gérard R, Avignon B, Huber S, Benmansour F, Chen X, Villaseñor R, Braendli-Baiocco A, Festag M, Maunz A, Singer T, Schuler F, Roth AB.

Mol Ther Nucleic Acids. 2017 Mar 17;6:89-105. doi: 10.1016/j.omtn.2016.11.006. Epub 2016 Dec 10.


Weak-beam scanning transmission electron microscopy for quantitative dislocation density measurement in steels.

Yoshida K, Shimodaira M, Toyama T, Shimizu Y, Inoue K, Yoshiie T, Milan KJ, Gerard R, Nagai Y.

Microscopy (Oxf). 2017 Apr 1;66(2):120-130. doi: 10.1093/jmicro/dfw111.


Hawkins' type-II talar fracture with subtalar dislocation: A very unusual combination.

Gérard R, Kerfant N, Dubois de Mont Marin G, Stern R, Assal M.

Orthop Traumatol Surg Res. 2017 May;103(3):403-406. doi: 10.1016/j.otsr.2016.12.009. Epub 2017 Jan 11.


Adalimumab dose escalation is effective and well tolerated in Crohn's disease patients with secondary loss of response to adalimumab.

Duveau N, Nachury M, Gerard R, Branche J, Maunoury V, Boualit M, Wils P, Desreumaux P, Pariente B.

Dig Liver Dis. 2017 Feb;49(2):163-169. doi: 10.1016/j.dld.2016.11.002. Epub 2016 Nov 14.


Ileal or Anastomotic Location of Lesions Does Not Impact Rate of Postoperative Recurrence in Crohn's Disease Patients Classified i2 on the Rutgeerts Score.

Bayart P, Duveau N, Nachury M, Zerbib P, Gerard R, Branche J, Maunoury V, Wils P, Boruchowicz A, Boualit M, Laberenne JE, Manolache O, Desreumaux P, de Chambrun GP, Pariente B.

Dig Dis Sci. 2016 Oct;61(10):2986-2992. doi: 10.1007/s10620-016-4215-1. Epub 2016 Jul 11.


PDZK1 prevents neointima formation via suppression of breakpoint cluster region kinase in vascular smooth muscle.

Lee WR, Sacharidou A, Behling-Kelly E, Oltmann SC, Zhu W, Ahmed M, Gerard RD, Hui DY, Abe J, Shaul PW, Mineo C.

PLoS One. 2015 Apr 17;10(4):e0124494. doi: 10.1371/journal.pone.0124494. eCollection 2015.


Constitutive phosphorylation of cardiac myosin regulatory light chain in vivo.

Chang AN, Battiprolu PK, Cowley PM, Chen G, Gerard RD, Pinto JR, Hill JA, Baker AJ, Kamm KE, Stull JT.

J Biol Chem. 2015 Apr 24;290(17):10703-16. doi: 10.1074/jbc.M115.642165. Epub 2015 Mar 2.


The acetate/ACSS2 switch regulates HIF-2 stress signaling in the tumor cell microenvironment.

Chen R, Xu M, Nagati JS, Hogg RT, Das A, Gerard RD, Garcia JA.

PLoS One. 2015 Feb 17;10(2):e0116515. doi: 10.1371/journal.pone.0116515. eCollection 2015. Erratum in: PLoS One. 2015;10(3):e0123612.


White-to-brown metabolic conversion of human adipocytes by JAK inhibition.

Moisan A, Lee YK, Zhang JD, Hudak CS, Meyer CA, Prummer M, Zoffmann S, Truong HH, Ebeling M, Kiialainen A, Gérard R, Xia F, Schinzel RT, Amrein KE, Cowan CA.

Nat Cell Biol. 2015 Jan;17(1):57-67. doi: 10.1038/ncb3075. Epub 2014 Dec 8.


Disease modeling and phenotypic drug screening for diabetic cardiomyopathy using human induced pluripotent stem cells.

Drawnel FM, Boccardo S, Prummer M, Delobel F, Graff A, Weber M, Gérard R, Badi L, Kam-Thong T, Bu L, Jiang X, Hoflack JC, Kiialainen A, Jeworutzki E, Aoyama N, Carlson C, Burcin M, Gromo G, Boehringer M, Stahlberg H, Hall BJ, Magnone MC, Kolaja K, Chien KR, Bailly J, Iacone R.

Cell Rep. 2014 Nov 6;9(3):810-21. doi: 10.1016/j.celrep.2014.09.055. Epub 2014 Oct 30.


Genetic variants of ApoE and ApoER2 differentially modulate endothelial function.

Ulrich V, Konaniah ES, Herz J, Gerard RD, Jung E, Yuhanna IS, Ahmed M, Hui DY, Mineo C, Shaul PW.

Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):13493-8. doi: 10.1073/pnas.1402106111. Epub 2014 Sep 2.


An acetate switch regulates stress erythropoiesis.

Xu M, Nagati JS, Xie J, Li J, Walters H, Moon YA, Gerard RD, Huang CL, Comerford SA, Hammer RE, Horton JD, Chen R, Garcia JA.

Nat Med. 2014 Sep;20(9):1018-26. doi: 10.1038/nm.3587. Epub 2014 Aug 10.


TALEN-mediated somatic mutagenesis in murine models of cancer.

Zhang S, Li L, Kendrick SL, Gerard RD, Zhu H.

Cancer Res. 2014 Sep 15;74(18):5311-21. doi: 10.1158/0008-5472.CAN-14-0529. Epub 2014 Jul 28.


Cytoglobin modulates myogenic progenitor cell viability and muscle regeneration.

Singh S, Canseco DC, Manda SM, Shelton JM, Chirumamilla RR, Goetsch SC, Ye Q, Gerard RD, Schneider JW, Richardson JA, Rothermel BA, Mammen PP.

Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):E129-38. doi: 10.1073/pnas.1314962111. Epub 2013 Dec 23.


An immunological link between Candida albicans colonization and Crohn's disease.

Gerard R, Sendid B, Colombel JF, Poulain D, Jouault T.

Crit Rev Microbiol. 2015 Jun;41(2):135-9. doi: 10.3109/1040841X.2013.810587. Epub 2013 Jul 16. Review.


Metabolic hormone FGF21 is induced in ground squirrels during hibernation but its overexpression is not sufficient to cause torpor.

Nelson BT, Ding X, Boney-Montoya J, Gerard RD, Kliewer SA, Andrews MT.

PLoS One. 2013;8(1):e53574. doi: 10.1371/journal.pone.0053574. Epub 2013 Jan 2.


C/EBP transcription factors mediate epicardial activation during heart development and injury.

Huang GN, Thatcher JE, McAnally J, Kong Y, Qi X, Tan W, DiMaio JM, Amatruda JF, Gerard RD, Hill JA, Bassel-Duby R, Olson EN.

Science. 2012 Dec 21;338(6114):1599-603. doi: 10.1126/science.1229765. Epub 2012 Nov 15.


Nuclear receptors HNF4α and LRH-1 cooperate in regulating Cyp7a1 in vivo.

Kir S, Zhang Y, Gerard RD, Kliewer SA, Mangelsdorf DJ.

J Biol Chem. 2012 Nov 30;287(49):41334-41. doi: 10.1074/jbc.M112.421834. Epub 2012 Oct 4.


Scavenger receptor class B type I is a plasma membrane cholesterol sensor.

Saddar S, Carriere V, Lee WR, Tanigaki K, Yuhanna IS, Parathath S, Morel E, Warrier M, Sawyer JK, Gerard RD, Temel RE, Brown JM, Connelly M, Mineo C, Shaul PW.

Circ Res. 2013 Jan 4;112(1):140-51. doi: 10.1161/CIRCRESAHA.112.280081. Epub 2012 Sep 28.


The microRNA (miR)-199a/214 cluster mediates opposing effects of progesterone and estrogen on uterine contractility during pregnancy and labor.

Williams KC, Renthal NE, Gerard RD, Mendelson CR.

Mol Endocrinol. 2012 Nov;26(11):1857-67. doi: 10.1210/me.2012-1199. Epub 2012 Sep 12. Erratum in: Mol Endocrinol. 2013 Jan;27(1):188.


Foxk1 promotes cell proliferation and represses myogenic differentiation by regulating Foxo4 and Mef2.

Shi X, Wallis AM, Gerard RD, Voelker KA, Grange RW, DePinho RA, Garry MG, Garry DJ.

J Cell Sci. 2012 Nov 15;125(Pt 22):5329-37. doi: 10.1242/jcs.105239. Epub 2012 Sep 6.


The acetylase/deacetylase couple CREB-binding protein/Sirtuin 1 controls hypoxia-inducible factor 2 signaling.

Chen R, Xu M, Hogg RT, Li J, Little B, Gerard RD, Garcia JA.

J Biol Chem. 2012 Aug 31;287(36):30800-11. doi: 10.1074/jbc.M111.244780. Epub 2012 Jul 17.


Peptide targeting of adenoviral vectors to augment tumor gene transfer.

Ballard EN, Trinh VT, Hogg RT, Gerard RD.

Cancer Gene Ther. 2012 Jul;19(7):476-88. doi: 10.1038/cgt.2012.23. Epub 2012 May 18.


MicroRNA silencing improves the tumor specificity of adenoviral transgene expression.

Card PB, Hogg RT, Gil Del Alcazar CR, Gerard RD.

Cancer Gene Ther. 2012 Jul;19(7):451-9. doi: 10.1038/cgt.2012.16. Epub 2012 May 4.


MicroRNA-200a serves a key role in the decline of progesterone receptor function leading to term and preterm labor.

Williams KC, Renthal NE, Condon JC, Gerard RD, Mendelson CR.

Proc Natl Acad Sci U S A. 2012 May 8;109(19):7529-34. doi: 10.1073/pnas.1200650109. Epub 2012 Apr 23.


Metabolic stress-induced activation of FoxO1 triggers diabetic cardiomyopathy in mice.

Battiprolu PK, Hojayev B, Jiang N, Wang ZV, Luo X, Iglewski M, Shelton JM, Gerard RD, Rothermel BA, Gillette TG, Lavandero S, Hill JA.

J Clin Invest. 2012 Mar;122(3):1109-18. doi: 10.1172/JCI60329. Epub 2012 Feb 13.


Fibroblast growth factor 21 promotes bone loss by potentiating the effects of peroxisome proliferator-activated receptor γ.

Wei W, Dutchak PA, Wang X, Ding X, Wang X, Bookout AL, Goetz R, Mohammadi M, Gerard RD, Dechow PC, Mangelsdorf DJ, Kliewer SA, Wan Y.

Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):3143-8. doi: 10.1073/pnas.1200797109. Epub 2012 Feb 6.


Human 1-acylglycerol-3-phosphate O-acyltransferase isoforms 1 and 2: biochemical characterization and inability to rescue hepatic steatosis in Agpat2(-/-) gene lipodystrophic mice.

Agarwal AK, Sukumaran S, Cortés VA, Tunison K, Mizrachi D, Sankella S, Gerard RD, Horton JD, Garg A.

J Biol Chem. 2011 Oct 28;286(43):37676-91. doi: 10.1074/jbc.M111.250449. Epub 2011 Aug 27.


The effect of collateral ligament release on ankle dorsiflexion: an anatomical study.

Gérard R, Unno-Veith F, Fasel J, Stern R, Assal M.

Foot Ankle Surg. 2011 Sep;17(3):193-6. doi: 10.1016/j.fas.2010.06.004. Epub 2010 Jul 15.


FGF15/19 regulates hepatic glucose metabolism by inhibiting the CREB-PGC-1α pathway.

Potthoff MJ, Boney-Montoya J, Choi M, He T, Sunny NE, Satapati S, Suino-Powell K, Xu HE, Gerard RD, Finck BN, Burgess SC, Mangelsdorf DJ, Kliewer SA.

Cell Metab. 2011 Jun 8;13(6):729-38. doi: 10.1016/j.cmet.2011.03.019.


Regulator of G protein signaling (RGS16) inhibits hepatic fatty acid oxidation in a carbohydrate response element-binding protein (ChREBP)-dependent manner.

Pashkov V, Huang J, Parameswara VK, Kedzierski W, Kurrasch DM, Tall GG, Esser V, Gerard RD, Uyeda K, Towle HC, Wilkie TM.

J Biol Chem. 2011 Apr 29;286(17):15116-25. doi: 10.1074/jbc.M110.216234. Epub 2011 Feb 27.


Hypoxia increases sirtuin 1 expression in a hypoxia-inducible factor-dependent manner.

Chen R, Dioum EM, Hogg RT, Gerard RD, Garcia JA.

J Biol Chem. 2011 Apr 22;286(16):13869-78. doi: 10.1074/jbc.M110.175414. Epub 2011 Feb 23.


Retargeting adenoviral vectors to improve gene transfer into tumors.

Hogg RT, Thorpe P, Gerard RD.

Cancer Gene Ther. 2011 Apr;18(4):275-87. doi: 10.1038/cgt.2010.78. Epub 2010 Dec 24.


miR-200 family and targets, ZEB1 and ZEB2, modulate uterine quiescence and contractility during pregnancy and labor.

Renthal NE, Chen CC, Williams KC, Gerard RD, Prange-Kiel J, Mendelson CR.

Proc Natl Acad Sci U S A. 2010 Nov 30;107(48):20828-33. doi: 10.1073/pnas.1008301107. Epub 2010 Nov 15.


[Use of dermal substitute Matriderm® in severe injuries of the hand: about one case].

Kerfant N, Gérard R, Le Nen D, Hu W.

Chir Main. 2010 Dec;29(6):378-80. doi: 10.1016/j.main.2010.09.024. Epub 2010 Oct 21. French.


Optimizing diabetes care regarding cardiovascular targets at general practice level: Direct@GP.

Wens J, Gerard R, Vandenberghe H.

Prim Care Diabetes. 2011 Apr;5(1):19-24. doi: 10.1016/j.pcd.2010.09.006. Epub 2010 Oct 27.


Conditional HIF-1alpha expression produces a reversible cardiomyopathy.

Bekeredjian R, Walton CB, MacCannell KA, Ecker J, Kruse F, Outten JT, Sutcliffe D, Gerard RD, Bruick RK, Shohet RV.

PLoS One. 2010 Jul 21;5(7):e11693. doi: 10.1371/journal.pone.0011693.


Myocardin-related transcription factor-a controls myofibroblast activation and fibrosis in response to myocardial infarction.

Small EM, Thatcher JE, Sutherland LB, Kinoshita H, Gerard RD, Richardson JA, Dimaio JM, Sadek H, Kuwahara K, Olson EN.

Circ Res. 2010 Jul 23;107(2):294-304. doi: 10.1161/CIRCRESAHA.110.223172. Epub 2010 Jun 17.


Surfactant protein A2 mutations associated with pulmonary fibrosis lead to protein instability and endoplasmic reticulum stress.

Maitra M, Wang Y, Gerard RD, Mendelson CR, Garcia CK.

J Biol Chem. 2010 Jul 16;285(29):22103-13. doi: 10.1074/jbc.M110.121467. Epub 2010 May 13.


The concept of locking plates.

Cronier P, Pietu G, Dujardin C, Bigorre N, Ducellier F, Gerard R.

Orthop Traumatol Surg Res. 2010 May 4. [Epub ahead of print]


The CCAAT/enhancer binding protein beta (C/EBPbeta) cooperates with NFAT to control expression of the calcineurin regulatory protein RCAN1-4.

Oh M, Dey A, Gerard RD, Hill JA, Rothermel BA.

J Biol Chem. 2010 May 28;285(22):16623-31. doi: 10.1074/jbc.M109.098236. Epub 2010 Apr 6.


[Anatomic study and CT angiography with 3D reconstructions of the pulmonary arterial tree].

Seizeur R, Gérard R, Marion J, Lefèvre C, Nonent M, Forlodou P, Sénécail B.

Morphologie. 2010 Aug;94(306):45-50. doi: 10.1016/j.morpho.2010.02.004. Epub 2010 Mar 19. French.


Regulation of PI3-kinase/Akt signaling by muscle-enriched microRNA-486.

Small EM, O'Rourke JR, Moresi V, Sutherland LB, McAnally J, Gerard RD, Richardson JA, Olson EN.

Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4218-23. doi: 10.1073/pnas.1000300107. Epub 2010 Feb 8.


Adenoviral targeting of gene expression to tumors.

Hogg RT, Garcia JA, Gerard RD.

Cancer Gene Ther. 2010 Jun;17(6):375-86. doi: 10.1038/cgt.2010.1. Epub 2010 Feb 5.


Cardiac myosin is a substrate for zipper-interacting protein kinase (ZIPK).

Chang AN, Chen G, Gerard RD, Kamm KE, Stull JT.

J Biol Chem. 2010 Feb 19;285(8):5122-6. doi: 10.1074/jbc.C109.076489. Epub 2009 Dec 28.

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