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Items: 1 to 50 of 84

1.

A Soluble Metabolon Synthesizes the Isoprenoid Lipid Ubiquinone.

Hajj Chehade M, Pelosi L, Fyfe CD, Loiseau L, Rascalou B, Brugière S, Kazemzadeh K, Vo CD, Ciccone L, Aussel L, Couté Y, Fontecave M, Barras F, Lombard M, Pierrel F.

Cell Chem Biol. 2018 Dec 17. pii: S2451-9456(18)30439-2. doi: 10.1016/j.chembiol.2018.12.001. [Epub ahead of print]

PMID:
30686758
2.

Dietary carbohydrate rather than protein intake drives colonic microbial fermentation during weight loss.

Gratz SW, Hazim S, Richardson AJ, Scobbie L, Johnstone AM, Fyfe C, Holtrop G, Lobley GE, Russell WR.

Eur J Nutr. 2018 Feb 20. doi: 10.1007/s00394-018-1629-x. [Epub ahead of print]

PMID:
29464347
3.

Evaluating a community-based public health intervention using a complex systems approach.

Matheson A, Walton M, Gray R, Lindberg K, Shanthakumar M, Fyfe C, Wehipeihana N, Borman B.

J Public Health (Oxf). 2018 Sep 1;40(3):606-613. doi: 10.1093/pubmed/fdx117.

PMID:
28977467
4.

Heterocyclyl tetracyclines. 2. 7-Methoxy-8-pyrrolidinyltetracyclines: discovery of TP-2758, a potent, orally efficacious antimicrobial against Gram-negative pathogens.

Sun C, Deng Y, Hunt DK, Fyfe C, Chen CL, Clark RB, Grossman TH, Sutcliffe JA, Xiao XY.

J Antibiot (Tokyo). 2018 Feb;71(2):287-297. doi: 10.1038/ja.2017.86. Epub 2017 Jul 26.

PMID:
28743974
5.

The UbiK protein is an accessory factor necessary for bacterial ubiquinone (UQ) biosynthesis and forms a complex with the UQ biogenesis factor UbiJ.

Loiseau L, Fyfe C, Aussel L, Hajj Chehade M, Hernández SB, Faivre B, Hamdane D, Mellot-Draznieks C, Rascalou B, Pelosi L, Velours C, Cornu D, Lombard M, Casadesús J, Pierrel F, Fontecave M, Barras F.

J Biol Chem. 2017 Jul 14;292(28):11937-11950. doi: 10.1074/jbc.M117.789164. Epub 2017 May 30.

6.

Fluorocycline TP-271 Is Potent against Complicated Community-Acquired Bacterial Pneumonia Pathogens.

Grossman TH, Fyfe C, O'Brien W, Hackel M, Minyard MB, Waites KB, Dubois J, Murphy TM, Slee AM, Weiss WJ, Sutcliffe JA.

mSphere. 2017 Feb 22;2(1). pii: e00004-17. doi: 10.1128/mSphere.00004-17. eCollection 2017 Jan-Feb.

7.

Heterocyclyl Tetracyclines. 1. 7-Trifluoromethyl-8-Pyrrolidinyltetracyclines: Potent, Broad Spectrum Antibacterial Agents with Enhanced Activity against Pseudomonas aeruginosa.

Deng Y, Sun C, Hunt DK, Fyfe C, Chen CL, Grossman TH, Sutcliffe JA, Xiao XY.

J Med Chem. 2017 Mar 23;60(6):2498-2512. doi: 10.1021/acs.jmedchem.6b01903. Epub 2017 Mar 15.

PMID:
28248499
8.

Eravacycline Is Active against Bacterial Isolates Expressing the Polymyxin Resistance Gene mcr-1.

Fyfe C, LeBlanc G, Close B, Nordmann P, Dumas J, Grossman TH.

Antimicrob Agents Chemother. 2016 Oct 21;60(11):6989-6990. doi: 10.1128/AAC.01646-16. Print 2016 Nov. No abstract available.

9.

Resistance to Macrolide Antibiotics in Public Health Pathogens.

Fyfe C, Grossman TH, Kerstein K, Sutcliffe J.

Cold Spring Harb Perspect Med. 2016 Oct 3;6(10). pii: a025395. doi: 10.1101/cshperspect.a025395. Review.

10.

A cost effectiveness analysis of community water fluoridation in New Zealand.

Fyfe C, Borman B, Scott G, Birks S.

N Z Med J. 2015 Dec 18;128(1427):38-46.

PMID:
26914003
11.

Bioprinting of human pluripotent stem cells and their directed differentiation into hepatocyte-like cells for the generation of mini-livers in 3D.

Faulkner-Jones A, Fyfe C, Cornelissen DJ, Gardner J, King J, Courtney A, Shu W.

Biofabrication. 2015 Oct 21;7(4):044102. doi: 10.1088/1758-5090/7/4/044102.

12.

Erratum for Grossman et al., target- and resistance-based mechanistic studies with TP-434, a novel fluorocycline antibiotic.

Grossman TH, Starosta AL, Fyfe C, O'Brien W, Rothstein DM, Mikolajka A, Wilson DN, Sutcliffe JA.

Antimicrob Agents Chemother. 2015 Sep;59(9):5870. doi: 10.1128/AAC.01551-15. No abstract available.

13.

Structure of protease-cleaved Escherichia coli α-2-macroglobulin reveals a putative mechanism of conformational activation for protease entrapment.

Fyfe CD, Grinter R, Josts I, Mosbahi K, Roszak AW, Cogdell RJ, Wall DM, Burchmore RJ, Byron O, Walker D.

Acta Crystallogr D Biol Crystallogr. 2015 Jul;71(Pt 7):1478-86. doi: 10.1107/S1399004715008548. Epub 2015 Jun 30.

14.

Design, Synthesis, and Biological Evaluation of Hexacyclic Tetracyclines as Potent, Broad Spectrum Antibacterial Agents.

Sun C, Hunt DK, Chen CL, Deng Y, He M, Clark RB, Fyfe C, Grossman TH, Sutcliffe JA, Xiao XY.

J Med Chem. 2015 Jun 11;58(11):4703-12. doi: 10.1021/acs.jmedchem.5b00262. Epub 2015 May 20.

PMID:
25927406
15.

Responses in gut hormones and hunger to diets with either high protein or a mixture of protein plus free amino acids supplied under weight-loss conditions.

Lobley GE, Holtrop G, Horgan GW, Bremner DM, Fyfe C, Johnstone AM.

Br J Nutr. 2015 Apr 28;113(8):1254-70. doi: 10.1017/S0007114515000069. Epub 2015 Mar 26.

PMID:
25809236
16.

The mother as hunter: significant reduction in foraging costs through enhancements of predation in maternal rats.

Kinsley CH, Blair JC, Karp NE, Hester NW, McNamara IM, Orthmeyer AL, McSweeney MC, Bardi MM, Karelina K, Christon LM, Sirkin MR, Victoria LW, Skurka DJ, Fyfe CR, Hudepohl MB, Felicio LF, Franssen RA, Meyer EE, da Silva IS, Lambert KG.

Horm Behav. 2014 Sep;66(4):649-54. doi: 10.1016/j.yhbeh.2014.09.004. Epub 2014 Sep 21.

PMID:
25240277
17.

Appetite control and biomarkers of satiety with vegetarian (soy) and meat-based high-protein diets for weight loss in obese men: a randomized crossover trial.

Neacsu M, Fyfe C, Horgan G, Johnstone AM.

Am J Clin Nutr. 2014 Aug;100(2):548-58. doi: 10.3945/ajcn.113.077503. Epub 2014 Jun 18.

PMID:
24944057
18.

Glucose uptake by the brain on chronic high-protein weight-loss diets with either moderate or low amounts of carbohydrate.

Lobley GE, Johnstone AM, Fyfe C, Horgan GW, Holtrop G, Bremner DM, Broom I, Schweiger L, Welch A.

Br J Nutr. 2014 Feb;111(4):586-97. doi: 10.1017/S0007114513002900.

PMID:
24528939
19.

Synthesis and biological evaluation of 8-aminomethyltetracycline derivatives as novel antibacterial agents.

Clark RB, He M, Deng Y, Sun C, Chen CL, Hunt DK, O'Brien WJ, Fyfe C, Grossman TH, Sutcliffe JA, Achorn C, Hogan PC, Katz CE, Niu J, Zhang WY, Zhu Z, Ronn M, Xiao XY.

J Med Chem. 2013 Oct 24;56(20):8112-38. doi: 10.1021/jm401211t. Epub 2013 Oct 3.

PMID:
24047201
20.

Antibacterial activity of eravacycline (TP-434), a novel fluorocycline, against hospital and community pathogens.

Sutcliffe JA, O'Brien W, Fyfe C, Grossman TH.

Antimicrob Agents Chemother. 2013 Nov;57(11):5548-58. doi: 10.1128/AAC.01288-13. Epub 2013 Aug 26.

21.

Fluoride and children's IQ.

Borman B, Fyfe C.

N Z Med J. 2013 May 31;126(1375):111-2. No abstract available.

PMID:
23824033
22.

A randomized crossover study to assess the effect of an oat-rich diet on glycaemic control, plasma lipids and postprandial glycaemia, inflammation and oxidative stress in Type 2 diabetes.

McGeoch SC, Johnstone AM, Lobley GE, Adamson J, Hickson K, Holtrop G, Fyfe C, Clark LF, Pearson DW, Abraham P, Megson IL, MacRury SM.

Diabet Med. 2013 Nov;30(11):1314-23. doi: 10.1111/dme.12228. Epub 2013 Jun 22.

23.

Assessing insect responses to climate change: What are we testing for? Where should we be heading?

Andrew NR, Hill SJ, Binns M, Bahar MH, Ridley EV, Jung MP, Fyfe C, Yates M, Khusro M.

PeerJ. 2013 Feb 12;1:e11. doi: 10.7717/peerj.11. Print 2013.

24.

Susceptibility of tetracyclines to Tet(a) resistance is independent of interdomain loop sequence.

Fyfe C, Sutcliffe JA, Grossman TH.

Antimicrob Agents Chemother. 2013 May;57(5):2430-1. doi: 10.1128/AAC.00393-13. Epub 2013 Mar 11. No abstract available.

25.

Sustainable diets for the future: Can we contribute to reducing greenhouse gas emissions by eating a healthy diet?

Macdiarmid JI, Kyle J, Horgan GW, Loe J, Fyfe C, Johnstone A, McNeill G.

Am J Clin Nutr. 2012 Sep;96(3):632-9. doi: 10.3945/ajcn.112.038729. Epub 2012 Aug 1.

PMID:
22854399
26.

Diet composition is associated with endogenous formation of N-nitroso compounds in obese men.

Holtrop G, Johnstone AM, Fyfe C, Gratz SW.

J Nutr. 2012 Sep;142(9):1652-8. doi: 10.3945/jn.112.158824. Epub 2012 Jul 25.

PMID:
22833653
27.

Development and characterization of a Pseudomonas aeruginosa in vitro coupled transcription-translation assay system for evaluation of translation inhibitors.

Fyfe C, Sutcliffe JA, Grossman TH.

J Microbiol Methods. 2012 Sep;90(3):256-61. doi: 10.1016/j.mimet.2012.05.018. Epub 2012 Jun 5.

28.

Target- and resistance-based mechanistic studies with TP-434, a novel fluorocycline antibiotic.

Grossman TH, Starosta AL, Fyfe C, O'Brien W, Rothstein DM, Mikolajka A, Wilson DN, Sutcliffe JA.

Antimicrob Agents Chemother. 2012 May;56(5):2559-64. doi: 10.1128/AAC.06187-11. Epub 2012 Feb 21. Erratum in: Antimicrob Agents Chemother. 2015 Sep;59(9):5870.

29.

Food intake and dietary glycaemic index in free-living adults with and without type 2 diabetes mellitus.

McGeoch SC, Holtrop G, Fyfe C, Lobley GE, Pearson DW, Abraham P, Megson IL, Macrury SM, Johnstone AM.

Nutrients. 2011 Jun;3(6):683-93. doi: 10.3390/nu3060683. Epub 2011 Jun 9.

30.

Fluorocyclines. 2. Optimization of the C-9 side-chain for antibacterial activity and oral efficacy.

Clark RB, Hunt DK, He M, Achorn C, Chen CL, Deng Y, Fyfe C, Grossman TH, Hogan PC, O'Brien WJ, Plamondon L, Rönn M, Sutcliffe JA, Zhu Z, Xiao XY.

J Med Chem. 2012 Jan 26;55(2):606-22. doi: 10.1021/jm201467r. Epub 2012 Jan 6.

PMID:
22148555
31.

Fluorocyclines. 1. 7-fluoro-9-pyrrolidinoacetamido-6-demethyl-6-deoxytetracycline: a potent, broad spectrum antibacterial agent.

Xiao XY, Hunt DK, Zhou J, Clark RB, Dunwoody N, Fyfe C, Grossman TH, O'Brien WJ, Plamondon L, Rönn M, Sun C, Zhang WY, Sutcliffe JA.

J Med Chem. 2012 Jan 26;55(2):597-605. doi: 10.1021/jm201465w. Epub 2012 Jan 4.

PMID:
22148514
32.

Effects of a high-protein, low-carbohydrate v. high-protein, moderate-carbohydrate weight-loss diet on antioxidant status, endothelial markers and plasma indices of the cardiometabolic profile.

Johnstone AM, Lobley GE, Horgan GW, Bremner DM, Fyfe CL, Morrice PC, Duthie GG.

Br J Nutr. 2011 Jul;106(2):282-91. doi: 10.1017/S0007114511000092.

PMID:
21521539
33.

8-Azatetracyclines: synthesis and evaluation of a novel class of tetracycline antibacterial agents.

Clark RB, He M, Fyfe C, Lofland D, O'Brien WJ, Plamondon L, Sutcliffe JA, Xiao XY.

J Med Chem. 2011 Mar 10;54(5):1511-28. doi: 10.1021/jm1015389. Epub 2011 Feb 8.

34.

Introduction.

Fyfe C, Gorban A.

Int J Neural Syst. 2010 Jun;20(3):v-vii. No abstract available.

PMID:
20560239
35.

Evaluating energy intake measurement in free-living subjects: when to record and for how long?

Fyfe CL, Stewart J, Murison SD, Jackson DM, Rance K, Speakman JR, Horgan GW, Johnstone AM.

Public Health Nutr. 2010 Feb;13(2):172-80. doi: 10.1017/S1368980009991443. Epub 2009 Sep 22.

PMID:
19772686
36.

Topological mappings of video and audio data.

Fyfe C, Barbakh W, Ooi WC, Ko H.

Int J Neural Syst. 2008 Dec;18(6):481-9.

PMID:
19145664
37.

Effects of conjugated linoleic acid plus n-3 polyunsaturated fatty acids on insulin secretion and estimated insulin sensitivity in men.

Ahrén B, Mari A, Fyfe CL, Tsofliou F, Sneddon AA, Wahle KW, Winzell MS, Pacini G, Williams LM.

Eur J Clin Nutr. 2009 Jun;63(6):778-86. doi: 10.1038/ejcn.2008.45. Epub 2008 Sep 3.

PMID:
18772894
38.

Two forms of immediate reward reinforcement learning for exploratory data analysis.

Wu Y, Fyfe C, Lai PL.

Neural Netw. 2008 Aug;21(6):847-55. doi: 10.1016/j.neunet.2008.06.013. Epub 2008 Jun 28.

PMID:
18662854
39.

Online clustering algorithms.

Barbakh W, Fyfe C.

Int J Neural Syst. 2008 Jun;18(3):185-94.

PMID:
18595148
40.

Effect of a conjugated linoleic acid and omega-3 fatty acid mixture on body composition and adiponectin.

Sneddon AA, Tsofliou F, Fyfe CL, Matheson I, Jackson DM, Horgan G, Winzell MS, Wahle KW, Ahren B, Williams LM.

Obesity (Silver Spring). 2008 May;16(5):1019-24. doi: 10.1038/oby.2008.41. Epub 2008 Mar 6.

41.
42.
44.

The combined use of self-organizing maps and Andrews' Curves.

García-Osorio C, Fyfe C.

Int J Neural Syst. 2005 Jun;15(3):197-206.

PMID:
16013090
46.

Determining the geometry of strongly hydrogen-bonded silanols in a layered hydrous silicate by solid-state nuclear magnetic resonance.

Gardiennet C, Marica F, Fyfe CA, Tekely P.

J Chem Phys. 2005 Feb 1;122(5):54705. Erratum in: J Chem Phys. 2005 Feb 22;122(8):089902.

PMID:
15740344
47.
48.

Zeolite nanoclusters coated onto the mesopore walls of SBA-15.

Do TO, Nossov A, Springuel-Huet MA, Schneider C, Bretherton JL, Fyfe CA, Kaliaguine S.

J Am Chem Soc. 2004 Nov 10;126(44):14324-5.

PMID:
15521730
49.

Twinned principal curves.

Koetsier J, Han Y, Fyfe C.

Neural Netw. 2004 Apr;17(3):399-409.

PMID:
15037357
50.

A canonical correlation neural network for multicollinearity and functional data.

Gou Z, Fyfe C.

Neural Netw. 2004 Mar;17(2):285-93.

PMID:
15036345

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