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Items: 1 to 50 of 1283

1.

On the G Protein-Coupled Receptor Neuromodulation of the Claustrum.

Borroto-Escuela DO, Fuxe K.

Neurochem Res. 2019 Jun 6. doi: 10.1007/s11064-019-02822-4. [Epub ahead of print]

PMID:
31172348
2.

Galanin (1-15)-fluoxetine interaction in the novel object recognition test. Involvement of 5-HT1A receptors in the prefrontal cortex of the rats.

Flores-Burgess A, Millón C, Gago B, García-Durán L, Cantero-García N, Coveñas R, Narváez JA, Fuxe K, Santín L, Díaz-Cabiale Z.

Neuropharmacology. 2019 May 22;155:104-112. doi: 10.1016/j.neuropharm.2019.05.023. [Epub ahead of print]

PMID:
31128121
3.

Role of the galanin N-terminal fragment (1-15) in anhedonia: Involvement of the dopaminergic mesolimbic system.

Millón C, Flores-Burgess A, Gago B, Alén F, Orio L, García-Durán L, Narváez JA, Fuxe K, Santín L, Díaz-Cabiale Z.

J Psychopharmacol. 2019 Jun;33(6):737-747. doi: 10.1177/0269881119844188. Epub 2019 May 13.

PMID:
31081442
4.

Understanding receptor heteromerization and its allosteric integration of signals.

Fuxe K, Borroto-Escuela DO.

Neuropharmacology. 2019 May 2. pii: S0028-3908(19)30151-0. doi: 10.1016/j.neuropharm.2019.05.001. [Epub ahead of print] No abstract available.

PMID:
31054939
5.

Attenuation of Oxytocin and Serotonin 2A Receptor Signaling through Novel Heteroreceptor Formation.

Chruścicka B, Wallace Fitzsimons SE, Borroto-Escuela DO, Druelle C, Stamou P, Nally K, Dinan TG, Cryan JF, Fuxe K, Schellekens H.

ACS Chem Neurosci. 2019 May 8. doi: 10.1021/acschemneuro.8b00665. [Epub ahead of print]

PMID:
31038917
6.

Acute Cocaine Enhances Dopamine D2R Recognition and Signaling and Counteracts D2R Internalization in Sigma1R-D2R Heteroreceptor Complexes.

Borroto-Escuela DO, Narváez M, Romero-Fernández W, Pinton L, Wydra K, Filip M, Beggiato S, Tanganelli S, Ferraro L, Fuxe K.

Mol Neurobiol. 2019 Apr 10. doi: 10.1007/s12035-019-1580-8. [Epub ahead of print]

PMID:
30972626
7.

On Nobel Laureate Arvid Carlsson.

Fuxe K.

J Neural Transm (Vienna). 2019 Apr;126(4):357. doi: 10.1007/s00702-019-01994-1. No abstract available.

PMID:
30888512
8.

Adenosine heteroreceptor complexes in the basal ganglia are implicated in Parkinson's disease and its treatment.

Borroto-Escuela DO, Fuxe K.

J Neural Transm (Vienna). 2019 Apr;126(4):455-471. doi: 10.1007/s00702-019-01969-2. Epub 2019 Jan 14.

9.

Effects of intra-accumbal or intra-prefrontal cortex microinjections of adenosine 2A receptor ligands on responses to cocaine reward and seeking in rats.

Wydra K, Suder A, Frankowska M, Borroto Escuela DO, Fuxe K, Filip M.

Psychopharmacology (Berl). 2018 Dec;235(12):3509-3523. doi: 10.1007/s00213-018-5072-8. Epub 2018 Nov 13.

10.

A2AR-D2R Heteroreceptor Complexes in Cocaine Reward and Addiction.

Borroto-Escuela DO, Wydra K, Filip M, Fuxe K.

Trends Pharmacol Sci. 2018 Dec;39(12):1008-1020. doi: 10.1016/j.tips.2018.10.007. Epub 2018 Oct 29. Review.

PMID:
30384981
11.

Mapping the Interface of a GPCR Dimer: A Structural Model of the A2A Adenosine and D2 Dopamine Receptor Heteromer.

Borroto-Escuela DO, Rodriguez D, Romero-Fernandez W, Kapla J, Jaiteh M, Ranganathan A, Lazarova T, Fuxe K, Carlsson J.

Front Pharmacol. 2018 Aug 30;9:829. doi: 10.3389/fphar.2018.00829. eCollection 2018.

12.

Brain of the tree pangolin (Manis tricuspis). III. The unusual locus coeruleus complex.

Imam A, Bhagwandin A, Ajao MS, Ihunwo AO, Fuxe K, Manger PR.

J Comp Neurol. 2018 Nov 1;526(16):2570-2684. doi: 10.1002/cne.24519. Epub 2018 Oct 16.

PMID:
30125941
13.

Glutamate heteroreceptor complexes in the brain.

Borroto-Escuela DO, Tarakanov AO, Brito I, Fuxe K.

Pharmacol Rep. 2018 Oct;70(5):936-950. doi: 10.1016/j.pharep.2018.04.002. Epub 2018 Apr 11. Review.

PMID:
30103174
14.

Brain Dopamine Transmission in Health and Parkinson's Disease: Modulation of Synaptic Transmission and Plasticity Through Volume Transmission and Dopamine Heteroreceptors.

Borroto-Escuela DO, Perez De La Mora M, Manger P, Narváez M, Beggiato S, Crespo-Ramírez M, Navarro G, Wydra K, Díaz-Cabiale Z, Rivera A, Ferraro L, Tanganelli S, Filip M, Franco R, Fuxe K.

Front Synaptic Neurosci. 2018 Jul 10;10:20. doi: 10.3389/fnsyn.2018.00020. eCollection 2018. Review.

15.

Dopamine D2 Receptor Supersensitivity as a Spectrum of Neurotoxicity and Status in Psychiatric Disorders.

Kostrzewa RM, Wydra K, Filip M, Crawford CA, McDougall SA, Brown RW, Borroto-Escuela DO, Fuxe K, Gainetdinov RR.

J Pharmacol Exp Ther. 2018 Sep;366(3):519-526. doi: 10.1124/jpet.118.247981. Epub 2018 Jun 19.

PMID:
29921706
16.

Receptor⁻Receptor Interactions in Multiple 5-HT1A Heteroreceptor Complexes in Raphe-Hippocampal 5-HT Transmission and Their Relevance for Depression and Its Treatment.

Borroto-Escuela DO, Narváez M, Ambrogini P, Ferraro L, Brito I, Romero-Fernandez W, Andrade-Talavera Y, Flores-Burgess A, Millon C, Gago B, Narvaez JA, Odagaki Y, Palkovits M, Diaz-Cabiale Z, Fuxe K.

Molecules. 2018 Jun 3;23(6). pii: E1341. doi: 10.3390/molecules23061341. Review.

17.

Neuronal adenosine A2A receptor overexpression is neuroprotective towards 3-nitropropionic acid-induced striatal toxicity: a rat model of Huntington's disease.

Domenici MR, Chiodi V, Averna M, Armida M, Pèzzola A, Pepponi R, Ferrante A, Bader M, Fuxe K, Popoli P.

Purinergic Signal. 2018 Sep;14(3):235-243. doi: 10.1007/s11302-018-9609-4. Epub 2018 May 16.

18.

A Novel Integrative Mechanism in Anxiolytic Behavior Induced by Galanin 2/Neuropeptide Y Y1 Receptor Interactions on Medial Paracapsular Intercalated Amygdala in Rats.

Narváez M, Borroto-Escuela DO, Santín L, Millón C, Gago B, Flores-Burgess A, Barbancho MA, Pérez de la Mora M, Narváez J, Díaz-Cabiale Z, Fuxe K.

Front Cell Neurosci. 2018 May 1;12:119. doi: 10.3389/fncel.2018.00119. eCollection 2018.

19.

Transcriptomic integration of D4R and MOR signaling in the rat caudate putamen.

Valderrama-Carvajal A, Irizar H, Gago B, Jiménez-Urbieta H, Fuxe K, Rodríguez-Oroz MC, Otaegui D, Rivera A.

Sci Rep. 2018 May 9;8(1):7337. doi: 10.1038/s41598-018-25604-4.

20.

Adenosine A2A receptor ligand recognition and signaling is blocked by A2B receptors.

Hinz S, Navarro G, Borroto-Escuela D, Seibt BF, Ammon YC, de Filippo E, Danish A, Lacher SK, Červinková B, Rafehi M, Fuxe K, Schiedel AC, Franco R, Müller CE.

Oncotarget. 2018 Feb 6;9(17):13593-13611. doi: 10.18632/oncotarget.24423. eCollection 2018 Mar 2.

21.

Understanding the Role of Adenosine A2AR Heteroreceptor Complexes in Neurodegeneration and Neuroinflammation.

Borroto-Escuela DO, Hinz S, Navarro G, Franco R, Müller CE, Fuxe K.

Front Neurosci. 2018 Feb 6;12:43. doi: 10.3389/fnins.2018.00043. eCollection 2018.

22.

Disruption of A2AR-D2R Heteroreceptor Complexes After A2AR Transmembrane 5 Peptide Administration Enhances Cocaine Self-Administration in Rats.

Borroto-Escuela DO, Wydra K, Li X, Rodriguez D, Carlsson J, Jastrzębska J, Filip M, Fuxe K.

Mol Neurobiol. 2018 Aug;55(8):7038-7048. doi: 10.1007/s12035-018-0887-1. Epub 2018 Jan 30.

23.

Differential activation of arginine-vasopressin receptor subtypes in the amygdaloid modulation of anxiety in the rat by arginine-vasopressin.

Hernández-Pérez OR, Crespo-Ramírez M, Cuza-Ferrer Y, Anias-Calderón J, Zhang L, Roldan-Roldan G, Aguilar-Roblero R, Borroto-Escuela DO, Fuxe K, Perez de la Mora M.

Psychopharmacology (Berl). 2018 Apr;235(4):1015-1027. doi: 10.1007/s00213-017-4817-0. Epub 2018 Jan 7.

PMID:
29306965
24.

Central administration of galanin N-terminal fragment 1-15 decreases the voluntary alcohol intake in rats.

Millón C, Flores-Burgess A, Castilla-Ortega E, Gago B, García-Fernandez M, Serrano A, Rodriguez de Fonseca F, Narváez JA, Fuxe K, Santín L, Díaz-Cabiale Z.

Addict Biol. 2019 Jan;24(1):76-87. doi: 10.1111/adb.12582. Epub 2017 Dec 6.

PMID:
29210146
25.

Effects of Long-Term Alcohol Drinking on the Dopamine D2 Receptor: Gene Expression and Heteroreceptor Complexes in the Striatum in Rats.

Feltmann K, Borroto-Escuela DO, Rüegg J, Pinton L, de Oliveira Sergio T, Narváez M, Jimenez-Beristain A, Ekström TJ, Fuxe K, Steensland P.

Alcohol Clin Exp Res. 2018 Feb;42(2):338-351. doi: 10.1111/acer.13568. Epub 2018 Jan 24.

26.

Disturbances in the FGFR1-5-HT1A Heteroreceptor Complexes in the Raphe-Hippocampal 5-HT System Develop in a Genetic Rat Model of Depression.

Borroto-Escuela DO, DuPont CM, Li X, Savelli D, Lattanzi D, Srivastava I, Narváez M, Di Palma M, Barbieri E, Andrade-Talavera Y, Cuppini R, Odagaki Y, Palkovits M, Ambrogini P, Lindskog M, Fuxe K.

Front Cell Neurosci. 2017 Oct 10;11:309. doi: 10.3389/fncel.2017.00309. eCollection 2017.

27.

Cocaine modulates allosteric D21 receptor-receptor interactions on dopamine and glutamate nerve terminals from rat striatum.

Beggiato S, Borelli AC, Borroto-Escuela D, Corbucci I, Tomasini MC, Marti M, Antonelli T, Tanganelli S, Fuxe K, Ferraro L.

Cell Signal. 2017 Dec;40:116-124. doi: 10.1016/j.cellsig.2017.09.007. Epub 2017 Sep 18.

PMID:
28923416
28.

Existence of Brain 5-HT1A-5-HT2A Isoreceptor Complexes with Antagonistic Allosteric Receptor-Receptor Interactions Regulating 5-HT1A Receptor Recognition.

Borroto-Escuela DO, Li X, Tarakanov AO, Savelli D, Narváez M, Shumilov K, Andrade-Talavera Y, Jimenez-Beristain A, Pomierny B, Díaz-Cabiale Z, Cuppini R, Ambrogini P, Lindskog M, Fuxe K.

ACS Omega. 2017 Aug 31;2(8):4779-4789. doi: 10.1021/acsomega.7b00629. Epub 2017 Aug 22.

29.

Receptor-heteromer mediated regulation of endocannabinoid signaling in activated microglia. Role of CB1 and CB2 receptors and relevance for Alzheimer's disease and levodopa-induced dyskinesia.

Navarro G, Borroto-Escuela D, Angelats E, Etayo Í, Reyes-Resina I, Pulido-Salgado M, Rodríguez-Pérez AI, Canela EI, Saura J, Lanciego JL, Labandeira-García JL, Saura CA, Fuxe K, Franco R.

Brain Behav Immun. 2018 Jan;67:139-151. doi: 10.1016/j.bbi.2017.08.015. Epub 2017 Aug 24.

PMID:
28843453
30.

Cocaine self-administration specifically increases A2AR-D2R and D2R-sigma1R heteroreceptor complexes in the rat nucleus accumbens shell. Relevance for cocaine use disorder.

Borroto-Escuela DO, Narváez M, Wydra K, Pintsuk J, Pinton L, Jimenez-Beristain A, Di Palma M, Jastrzębska J, Filip M, Fuxe K.

Pharmacol Biochem Behav. 2017 Apr;155:24-31. doi: 10.1016/j.pbb.2017.03.003. Epub 2017 Mar 12.

PMID:
28300546
31.

Galanin (1-15) enhancement of the behavioral effects of Fluoxetine in the forced swimming test gives a new therapeutic strategy against depression.

Flores-Burgess A, Millón C, Gago B, Narváez M, Borroto-Escuela DO, Mengod G, Narváez JA, Fuxe K, Santín L, Díaz-Cabiale Z.

Neuropharmacology. 2017 May 15;118:233-241. doi: 10.1016/j.neuropharm.2017.03.010. Epub 2017 Mar 11.

PMID:
28288814
32.

Understanding the Role of GPCR Heteroreceptor Complexes in Modulating the Brain Networks in Health and Disease.

Borroto-Escuela DO, Carlsson J, Ambrogini P, Narváez M, Wydra K, Tarakanov AO, Li X, Millón C, Ferraro L, Cuppini R, Tanganelli S, Liu F, Filip M, Diaz-Cabiale Z, Fuxe K.

Front Cell Neurosci. 2017 Feb 21;11:37. doi: 10.3389/fncel.2017.00037. eCollection 2017. Review.

33.

IL1R2, CCR2, and CXCR4 May Form Heteroreceptor Complexes with NMDAR and D2R: Relevance for Schizophrenia.

Borroto-Escuela DO, Tarakanov AO, Bechter K, Fuxe K.

Front Psychiatry. 2017 Feb 15;8:24. doi: 10.3389/fpsyt.2017.00024. eCollection 2017.

34.

Is There Volume Transmission Along Extracellular Fluid Pathways Corresponding to the Acupuncture Meridians?

Zhang W, Wang Z, Jia S, Tian Y, Wang G, Li H, Fuxe K.

J Acupunct Meridian Stud. 2017 Jan;10(1):5-19. doi: 10.1016/j.jams.2016.12.004. Epub 2016 Dec 18.

35.

The neuropeptides Galanin and Galanin(1-15) in depression-like behaviours.

Millón C, Flores-Burgess A, Narváez M, Borroto-Escuela DO, Gago B, Santín L, Castilla-Ortega E, Narváez JÁ, Fuxe K, Díaz-Cabiale Z.

Neuropeptides. 2017 Aug;64:39-45. doi: 10.1016/j.npep.2017.01.004. Epub 2017 Jan 31. Review.

PMID:
28196617
36.

Alterations in ventral and dorsal striatal allosteric A2AR-D2R receptor-receptor interactions after amphetamine challenge: Relevance for schizophrenia.

Pintsuk J, Borroto-Escuela DO, Lai TK, Liu F, Fuxe K.

Life Sci. 2016 Oct 29. pii: S0024-3205(16)30629-4. doi: 10.1016/j.lfs.2016.10.027. [Epub ahead of print]

PMID:
27984074
37.

Hypothalamic Vasopressinergic Projections Innervate Central Amygdala GABAergic Neurons: Implications for Anxiety and Stress Coping.

Hernández VS, Hernández OR, Perez de la Mora M, Gómora MJ, Fuxe K, Eiden LE, Zhang L.

Front Neural Circuits. 2016 Nov 18;10:92. eCollection 2016.

38.

A2A-D2 receptor-receptor interaction modulates gliotransmitter release from striatal astrocyte processes.

Cervetto C, Venturini A, Passalacqua M, Guidolin D, Genedani S, Fuxe K, Borroto-Esquela DO, Cortelli P, Woods A, Maura G, Marcoli M, Agnati LF.

J Neurochem. 2017 Jan;140(2):268-279. doi: 10.1111/jnc.13885. Epub 2016 Nov 29.

39.

Understanding the Functional Plasticity in Neural Networks of the Basal Ganglia in Cocaine Use Disorder: A Role for Allosteric Receptor-Receptor Interactions in A2A-D2 Heteroreceptor Complexes.

Borroto-Escuela DO, Wydra K, Pintsuk J, Narvaez M, Corrales F, Zaniewska M, Agnati LF, Franco R, Tanganelli S, Ferraro L, Filip M, Fuxe K.

Neural Plast. 2016;2016:4827268. Epub 2016 Oct 30. Review.

40.

Diversity and bias through dopamine D2R heteroreceptor complexes.

Borroto-Escuela DO, Fuxe K.

Curr Opin Pharmacol. 2017 Feb;32:16-22. doi: 10.1016/j.coph.2016.10.004. Epub 2016 Nov 11. Review.

PMID:
27838588
41.

Existence of muscarinic acetylcholine receptor (mAChR) and fibroblast growth factor receptor (FGFR) heteroreceptor complexes and their enhancement of neurite outgrowth in neural hippocampal cultures.

Di Liberto V, Borroto-Escuela DO, Frinchi M, Verdi V, Fuxe K, Belluardo N, Mudò G.

Biochim Biophys Acta Gen Subj. 2017 Feb;1861(2):235-245. doi: 10.1016/j.bbagen.2016.10.026. Epub 2016 Nov 1.

PMID:
27815219
42.

Volume transmission and receptor-receptor interactions in heteroreceptor complexes: understanding the role of new concepts for brain communication.

Fuxe K, Borroto-Escuela DO.

Neural Regen Res. 2016 Aug;11(8):1220-3. doi: 10.4103/1673-5374.189168. Review.

43.

Participation of protein kinases in cytotoxic and proapoptotic effects of ethylene glycol ethers and their metabolites in SH-SY5Y cells.

Pomierny B, Fuxe K, Krzyżanowska W, Regulska M, Broniowska Ż, Budziszewska B.

Toxicol In Vitro. 2016 Oct;36:153-163. doi: 10.1016/j.tiv.2016.08.001. Epub 2016 Aug 4.

PMID:
27497993
44.

Signaling in dopamine D2 receptor-oxytocin receptor heterocomplexes and its relevance for the anxiolytic effects of dopamine and oxytocin interactions in the amygdala of the rat.

de la Mora MP, Pérez-Carrera D, Crespo-Ramírez M, Tarakanov A, Fuxe K, Borroto-Escuela DO.

Biochim Biophys Acta. 2016 Nov;1862(11):2075-2085. doi: 10.1016/j.bbadis.2016.07.004. Epub 2016 Jul 15.

45.

Dopamine D1 receptor activity is involved in the increased anxiety levels observed in STZ-induced diabetes in rats.

Rebolledo-Solleiro D, Araiza LFO, Broccoli L, Hansson AC, Rocha-Arrieta LL, Aguilar-Roblero R, Crespo-Ramírez M, Fuxe K, Pérez de la Mora M.

Behav Brain Res. 2016 Oct 15;313:293-301. doi: 10.1016/j.bbr.2016.06.060. Epub 2016 Jun 30.

PMID:
27374159
46.

Dopamine D4 receptor stimulation prevents nigrostriatal dopamine pathway activation by morphine: relevance for drug addiction.

Rivera A, Gago B, Suárez-Boomgaard D, Yoshitake T, Roales-Buján R, Valderrama-Carvajal A, Bilbao A, Medina-Luque J, Díaz-Cabiale Z, Craenenbroeck KV, Borroto-Escuela DO, Kehr J, Rodríguez de Fonseca F, Santín L, de la Calle A, Fuxe K.

Addict Biol. 2017 Sep;22(5):1232-1245. doi: 10.1111/adb.12407. Epub 2016 May 22.

PMID:
27212105
47.

Characterization of the interaction between the dopamine D4 receptor, KLHL12 and β-arrestins.

Skieterska K, Shen A, Clarisse D, Rondou P, Borroto-Escuela DO, Lintermans B, Fuxe K, Xiang YK, Van Craenenbroeck K.

Cell Signal. 2016 Aug;28(8):1001-14. doi: 10.1016/j.cellsig.2016.05.003. Epub 2016 May 5.

PMID:
27155323
48.

Multiple D2 heteroreceptor complexes: new targets for treatment of schizophrenia.

Borroto-Escuela DO, Pintsuk J, Schäfer T, Friedland K, Ferraro L, Tanganelli S, Liu F, Fuxe K.

Ther Adv Psychopharmacol. 2016 Apr;6(2):77-94. doi: 10.1177/2045125316637570. Epub 2016 Mar 10. Review.

49.

Functional role of striatal A2A, D2, and mGlu5 receptor interactions in regulating striatopallidal GABA neuronal transmission.

Beggiato S, Tomasini MC, Borelli AC, Borroto-Escuela DO, Fuxe K, Antonelli T, Tanganelli S, Ferraro L.

J Neurochem. 2016 Jul;138(2):254-64. doi: 10.1111/jnc.13652. Epub 2016 Jun 21.

50.

Telocytes in their context with other intercellular communication agents.

Edelstein L, Fuxe K, Levin M, Popescu BO, Smythies J.

Semin Cell Dev Biol. 2016 Jul;55:9-13. doi: 10.1016/j.semcdb.2016.03.010. Epub 2016 Mar 21. Review.

PMID:
27013113

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