Sort by
Items per page

Send to

Choose Destination

Search results

Items: 35


CXADR-Mediated Formation of an AKT Inhibitory Signalosome at Tight Junctions Controls Epithelial-Mesenchymal Plasticity in Breast Cancer.

Nilchian A, Johansson J, Ghalali A, Asanin ST, Santiago A, Rosencrantz O, Sollerbrant K, Vincent CT, Sund M, Stenius U, Fuxe J.

Cancer Res. 2019 Jan 1;79(1):47-60. doi: 10.1158/0008-5472.CAN-18-1742. Epub 2018 Nov 1.


EMT, inflammation and metastasis.

Vincent CT, Fuxe J.

Semin Cancer Biol. 2017 Dec;47:168-169. doi: 10.1016/j.semcancer.2017.09.003. Epub 2017 Sep 12. No abstract available.


Epithelial-mesenchymal transition in cancer metastasis through the lymphatic system.

Karlsson MC, Gonzalez SF, Welin J, Fuxe J.

Mol Oncol. 2017 Jul;11(7):781-791. doi: 10.1002/1878-0261.12092. Epub 2017 Jun 26. Review.


Coxsackie-adenovirus receptor expression is enhanced in pancreas from patients with type 1 diabetes.

Hodik M, Anagandula M, Fuxe J, Krogvold L, Dahl-Jørgensen K, Hyöty H, Sarmiento L, Frisk G; POD-V Consortium.

BMJ Open Diabetes Res Care. 2016 Nov 25;4(1):e000219. eCollection 2016.


Mesenchymal state of intimal cells may explain higher propensity to ascending aortic aneurysm in bicuspid aortic valves.

Maleki S, Kjellqvist S, Paloschi V, Magné J, Branca RM, Du L, Hultenby K, Petrini J, Fuxe J; MIBAVA Leducq Consortium, Lehtiö J, Franco-Cereceda A, Eriksson P, Björck HM.

Sci Rep. 2016 Oct 25;6:35712. doi: 10.1038/srep35712.


Reprogramming Tumor-Associated Macrophages by Antibody Targeting Inhibits Cancer Progression and Metastasis.

Georgoudaki AM, Prokopec KE, Boura VF, Hellqvist E, Sohn S, Östling J, Dahan R, Harris RA, Rantalainen M, Klevebring D, Sund M, Brage SE, Fuxe J, Rolny C, Li F, Ravetch JV, Karlsson MC.

Cell Rep. 2016 May 31;15(9):2000-11. doi: 10.1016/j.celrep.2016.04.084. Epub 2016 May 19.


TGF-β1-induced EMT promotes targeted migration of breast cancer cells through the lymphatic system by the activation of CCR7/CCL21-mediated chemotaxis.

Pang MF, Georgoudaki AM, Lambut L, Johansson J, Tabor V, Hagikura K, Jin Y, Jansson M, Alexander JS, Nelson CM, Jakobsson L, Betsholtz C, Sund M, Karlsson MC, Fuxe J.

Oncogene. 2016 Feb 11;35(6):748-60. doi: 10.1038/onc.2015.133. Epub 2015 May 11.


TGF-β1-Induced Epithelial-Mesenchymal Transition Promotes Monocyte/Macrophage Properties in Breast Cancer Cells.

Johansson J, Tabor V, Wikell A, Jalkanen S, Fuxe J.

Front Oncol. 2015 Jan 26;5:3. doi: 10.3389/fonc.2015.00003. eCollection 2015.


Pericytes contribute to airway remodeling in a mouse model of chronic allergic asthma.

Johnson JR, Folestad E, Rowley JE, Noll EM, Walker SA, Lloyd CM, Rankin SM, Pietras K, Eriksson U, Fuxe J.

Am J Physiol Lung Cell Mol Physiol. 2015 Apr 1;308(7):L658-71. doi: 10.1152/ajplung.00286.2014. Epub 2015 Jan 30.


Excessive vascular sprouting underlies cerebral hemorrhage in mice lacking αVβ8-TGFβ signaling in the brain.

Arnold TD, Niaudet C, Pang MF, Siegenthaler J, Gaengel K, Jung B, Ferrero GM, Mukouyama YS, Fuxe J, Akhurst R, Betsholtz C, Sheppard D, Reichardt LF.

Development. 2014 Dec;141(23):4489-99. doi: 10.1242/dev.107193. Epub 2014 Nov 18.


C/EBPβ expression is an independent predictor of overall survival in breast cancer patients by MHCII/CD4-dependent mechanism of metastasis formation.

Kurzejamska E, Johansson J, Jirström K, Prakash V, Ananthaseshan S, Boon L, Fuxe J, Religa P.

Oncogenesis. 2014 Nov 3;3:e125. doi: 10.1038/oncsis.2014.38.


MiR-155-mediated loss of C/EBPβ shifts the TGF-β response from growth inhibition to epithelial-mesenchymal transition, invasion and metastasis in breast cancer.

Johansson J, Berg T, Kurzejamska E, Pang MF, Tabor V, Jansson M, Roswall P, Pietras K, Sund M, Religa P, Fuxe J.

Oncogene. 2013 Dec 12;32(50):5614-24. doi: 10.1038/onc.2013.322. Epub 2013 Aug 19.


Human enterovirus species B in ileocecal Crohn's disease.

Nyström N, Berg T, Lundin E, Skog O, Hansson I, Frisk G, Juko-Pecirep I, Nilsson M, Gyllensten U, Finkel Y, Fuxe J, Wanders A.

Clin Transl Gastroenterol. 2013 Jun 27;4:e38. doi: 10.1038/ctg.2013.7.


Deficiency for endoglin in tumor vasculature weakens the endothelial barrier to metastatic dissemination.

Anderberg C, Cunha SI, Zhai Z, Cortez E, Pardali E, Johnson JR, Franco M, Páez-Ribes M, Cordiner R, Fuxe J, Johansson BR, Goumans MJ, Casanovas O, ten Dijke P, Arthur HM, Pietras K.

J Exp Med. 2013 Mar 11;210(3):563-79. doi: 10.1084/jem.20120662. Epub 2013 Feb 11.


The sphingosine-1-phosphate receptor S1PR1 restricts sprouting angiogenesis by regulating the interplay between VE-cadherin and VEGFR2.

Gaengel K, Niaudet C, Hagikura K, Laviña B, Muhl L, Hofmann JJ, Ebarasi L, Nyström S, Rymo S, Chen LL, Pang MF, Jin Y, Raschperger E, Roswall P, Schulte D, Benedito R, Larsson J, Hellström M, Fuxe J, Uhlén P, Adams R, Jakobsson L, Majumdar A, Vestweber D, Uv A, Betsholtz C.

Dev Cell. 2012 Sep 11;23(3):587-99. doi: 10.1016/j.devcel.2012.08.005. Erratum in: Dev Cell. 2012 Dec 11;23(6):1264. Laviña Siemsen, Bàrbara [corrected to Laviña, Bàrbara].


Repeated cisplatin treatment can lead to a multiresistant tumor cell population with stem cell features and sensitivity to 3-bromopyruvate.

Wintzell M, Löfstedt L, Johansson J, Pedersen AB, Fuxe J, Shoshan M.

Cancer Biol Ther. 2012 Dec;13(14):1454-62. doi: 10.4161/cbt.22007. Epub 2012 Sep 6.


TGF-β-induced epithelial-mesenchymal transition: a link between cancer and inflammation.

Fuxe J, Karlsson MC.

Semin Cancer Biol. 2012 Oct;22(5-6):455-61. doi: 10.1016/j.semcancer.2012.05.004. Epub 2012 May 22. Review.


Essential role of the coxsackie- and adenovirus receptor (CAR) in development of the lymphatic system in mice.

Mirza M, Pang MF, Zaini MA, Haiko P, Tammela T, Alitalo K, Philipson L, Fuxe J, Sollerbrant K.

PLoS One. 2012;7(5):e37523. doi: 10.1371/journal.pone.0037523. Epub 2012 May 18.


Pericyte requirement for anti-leak action of angiopoietin-1 and vascular remodeling in sustained inflammation.

Fuxe J, Tabruyn S, Colton K, Zaid H, Adams A, Baluk P, Lashnits E, Morisada T, Le T, O'Brien S, Epstein DM, Koh GY, McDonald DM.

Am J Pathol. 2011 Jun;178(6):2897-909. doi: 10.1016/j.ajpath.2011.02.008. Epub 2011 May 6.


Chronic respiratory aeroallergen exposure in mice induces epithelial-mesenchymal transition in the large airways.

Johnson JR, Roos A, Berg T, Nord M, Fuxe J.

PLoS One. 2011 Jan 20;6(1):e16175. doi: 10.1371/journal.pone.0016175.


Angiopoietin-2-driven vascular remodeling in airway inflammation.

Tabruyn SP, Colton K, Morisada T, Fuxe J, Wiegand SJ, Thurston G, Coyle AJ, Connor J, McDonald DM.

Am J Pathol. 2010 Dec;177(6):3233-43. doi: 10.2353/ajpath.2010.100059. Epub 2010 Oct 15.


Transcriptional crosstalk between TGF-β and stem cell pathways in tumor cell invasion: role of EMT promoting Smad complexes.

Fuxe J, Vincent T, Garcia de Herreros A.

Cell Cycle. 2010 Jun 15;9(12):2363-74. Epub 2010 Jun 15. Review.


Angiopoietin/Tie2 signaling transforms capillaries into venules primed for leukocyte trafficking in airway inflammation.

Fuxe J, Lashnits E, O'Brien S, Baluk P, Tabruyn SP, Kuhnert F, Kuo C, Thurston G, McDonald DM.

Am J Pathol. 2010 Apr;176(4):2009-18. doi: 10.2353/ajpath.2010.090976. Epub 2010 Feb 4.


Estrogen receptor-beta expression in human laryngeal carcinoma: correlation with the expression of epithelial-mesenchymal transition specific biomarkers.

Goulioumis AK, Fuxe J, Varakis J, Repanti M, Goumas P, Papadaki H.

Oncol Rep. 2009 Nov;22(5):1063-8.


A SNAIL1-SMAD3/4 transcriptional repressor complex promotes TGF-beta mediated epithelial-mesenchymal transition.

Vincent T, Neve EP, Johnson JR, Kukalev A, Rojo F, Albanell J, Pietras K, Virtanen I, Philipson L, Leopold PL, Crystal RG, de Herreros AG, Moustakas A, Pettersson RF, Fuxe J.

Nat Cell Biol. 2009 Aug;11(8):943-50. doi: 10.1038/ncb1905. Epub 2009 Jul 13.


Functionally specialized junctions between endothelial cells of lymphatic vessels.

Baluk P, Fuxe J, Hashizume H, Romano T, Lashnits E, Butz S, Vestweber D, Corada M, Molendini C, Dejana E, McDonald DM.

J Exp Med. 2007 Oct 1;204(10):2349-62. Epub 2007 Sep 10.


Induction of neutrophil gelatinase-associated lipocalin in vascular injury via activation of nuclear factor-kappaB.

Bu DX, Hemdahl AL, Gabrielsen A, Fuxe J, Zhu C, Eriksson P, Yan ZQ.

Am J Pathol. 2006 Dec;169(6):2245-53.


The coxsackie- and adenovirus receptor (CAR) is an in vivo marker for epithelial tight junctions, with a potential role in regulating permeability and tissue homeostasis.

Raschperger E, Thyberg J, Pettersson S, Philipson L, Fuxe J, Pettersson RF.

Exp Cell Res. 2006 May 15;312(9):1566-80. Epub 2006 Mar 15.


CLMP, a novel member of the CTX family and a new component of epithelial tight junctions.

Raschperger E, Engstrom U, Pettersson RF, Fuxe J.

J Biol Chem. 2004 Jan 2;279(1):796-804. Epub 2003 Oct 22.


VIPL, a VIP36-like membrane protein with a putative function in the export of glycoproteins from the endoplasmic reticulum.

Neve EP, Svensson K, Fuxe J, Pettersson RF.

Exp Cell Res. 2003 Aug 1;288(1):70-83.


Immortalization of bovine capillary endothelial cells by hTERT alone involves inactivation of endogenous p16INK4A/pRb.

Veitonmäki N, Fuxe J, Hultdin M, Roos G, Pettersson RF, Cao Y.

FASEB J. 2003 Apr;17(6):764-6. Epub 2003 Feb 5.


Expression of the coxsackie and adenovirus receptor in human astrocytic tumors and xenografts.

Fuxe J, Liu L, Malin S, Philipson L, Collins VP, Pettersson RF.

Int J Cancer. 2003 Mar 1;103(6):723-9.


The combination of HSV-tk and endostatin gene therapy eradicates orthotopic human renal cell carcinomas in nude mice.

Pulkkanen KJ, Laukkanen JM, Fuxe J, Kettunen MI, Rehn M, Kannasto JM, Parkkinen JJ, Kauppinen RA, Pettersson RF, Yla-Herttuala S.

Cancer Gene Ther. 2002 Nov;9(11):908-16.


Supplemental Content

Support Center