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Items: 1 to 50 of 339

1.

An influenza-derived membrane tension-modulating peptide regulates cell movement and morphology via actin remodeling.

Masuda T, Baba K, Nomura T, Tsujita K, Murayama T, Itoh T, Takatani-Nakase T, Sokabe M, Inagaki N, Futaki S.

Commun Biol. 2019 Jun 26;2:243. doi: 10.1038/s42003-019-0486-3. eCollection 2019.

2.

Loosening of Lipid Packing by Cell Surface Recruitment of Amphiphilic Peptides by Coiled-coil Tethering.

Sakai T, Kawano K, Iino M, Takeuchi T, Imanishi M, Futaki S.

Chembiochem. 2019 Jun 21. doi: 10.1002/cbic.201900347. [Epub ahead of print]

PMID:
31225928
3.

Cell-penetrating mechanism of intracellular targeting albumin: Contribution of macropinocytosis induction and endosomal escape.

Ichimizu S, Watanabe H, Maeda H, Hamasaki K, Ikegami K, Chuang VTG, Kinoshita R, Nishida K, Shimizu T, Ishima Y, Ishida T, Seki T, Katsuki H, Futaki S, Otagiri M, Maruyama T.

J Control Release. 2019 Jun 28;304:156-163. doi: 10.1016/j.jconrel.2019.05.015. Epub 2019 May 10.

PMID:
31082432
4.

Evaluation of Keratinocyte Proliferation on Two- and Three-dimensional Type I Collagen Substrates.

Fujisaki H, Futaki S, Mizuno K, Hattori S.

J Vis Exp. 2019 Apr 22;(146). doi: 10.3791/59339.

PMID:
31058893
5.

Inducible Membrane Permeabilization by Attenuated Lytic Peptides: A New Concept for Accessing Cell Interiors through Ruffled Membranes.

Akishiba M, Futaki S.

Mol Pharm. 2019 Jun 3;16(6):2540-2548. doi: 10.1021/acs.molpharmaceut.9b00156. Epub 2019 May 10.

PMID:
30945865
6.

Oligoarginine-Bearing Tandem Repeat Penetration-Accelerating Sequence Delivers Protein to Cytosol via Caveolae-Mediated Endocytosis.

Okuda A, Tahara S, Hirose H, Takeuchi T, Nakase I, Ono A, Takehashi M, Tanaka S, Futaki S.

Biomacromolecules. 2019 May 13;20(5):1849-1859. doi: 10.1021/acs.biomac.8b01299. Epub 2019 Apr 1.

PMID:
30893557
7.

Dipicolylamine/Metal Complexes that Promote Direct Cell-Membrane Penetration of Octaarginine.

Kawaguchi Y, Ise S, Azuma Y, Takeuchi T, Kawano K, Le TK, Ohkanda J, Futaki S.

Bioconjug Chem. 2019 Feb 20;30(2):454-460. doi: 10.1021/acs.bioconjchem.8b00691. Epub 2018 Nov 30.

PMID:
30428256
8.

Ventricular-subventricular zone fractones are speckled basement membranes that function as a neural stem cell niche.

Sato Y, Kiyozumi D, Futaki S, Nakano I, Shimono C, Kaneko N, Ikawa M, Okabe M, Sawamoto K, Sekiguchi K.

Mol Biol Cell. 2019 Jan 1;30(1):56-68. doi: 10.1091/mbc.E18-05-0286. Epub 2018 Oct 31.

9.

Enhanced expression of nidogen 1 around the nest of basal cell carcinoma compared with that around squamous cell carcinoma.

Hirakawa Y, Futaki S, Tanizaki H, Furukawa F, Maemura K, Kondo Y, Moriwaki S.

Med Mol Morphol. 2019 Jun;52(2):99-105. doi: 10.1007/s00795-018-0207-x. Epub 2018 Oct 1.

PMID:
30276677
10.

Respective optimal calcium concentrations for proliferation on type I collagen fibrils in two keratinocyte line cells, HaCaT and FEPE1L-8.

Fujisaki H, Futaki S, Yamada M, Sekiguchi K, Hayashi T, Ikejima T, Hattori S.

Regen Ther. 2018 May 24;8:73-79. doi: 10.1016/j.reth.2018.04.001. eCollection 2018 Jun.

11.

Modular Redesign of a Cationic Lytic Peptide To Promote the Endosomal Escape of Biomacromolecules.

Azuma Y, Imai H, Kawaguchi Y, Nakase I, Kimura H, Futaki S.

Angew Chem Int Ed Engl. 2018 Sep 24;57(39):12771-12774. doi: 10.1002/anie.201807534. Epub 2018 Aug 30.

PMID:
30101453
12.

Sequence-specific 5mC detection in live cells based on the TALE-split luciferase complementation system.

Tsuji S, Shinoda K, Futaki S, Imanishi M.

Analyst. 2018 Aug 6;143(16):3793-3797. doi: 10.1039/c8an00562a.

PMID:
30051128
13.

Delta-like 3 is silenced by HBx via histone acetylation in HBV-associated HCCs.

Hamamoto H, Maemura K, Matsuo K, Taniguchi K, Tanaka Y, Futaki S, Takeshita A, Asai A, Hayashi M, Hirose Y, Kondo Y, Uchiyama K.

Sci Rep. 2018 Mar 19;8(1):4842. doi: 10.1038/s41598-018-23318-1.

14.

Design and tuning of a cell-penetrating albumin derivative as a versatile nanovehicle for intracellular drug delivery.

Ichimizu S, Watanabe H, Maeda H, Hamasaki K, Nakamura Y, Chuang VTG, Kinoshita R, Nishida K, Tanaka R, Enoki Y, Ishima Y, Kuniyasu A, Kobashigawa Y, Morioka H, Futaki S, Otagiri M, Maruyama T.

J Control Release. 2018 May 10;277:23-34. doi: 10.1016/j.jconrel.2018.02.037. Epub 2018 Mar 10.

PMID:
29530390
15.

Expression of delta-like 3 is downregulated by aberrant DNA methylation and histone modification in hepatocellular carcinoma.

Mizuno Y, Maemura K, Tanaka Y, Hirata A, Futaki S, Hamamoto H, Taniguchi K, Hayashi M, Uchiyama K, Shibata MA, Otsuki Y, Kondo Y.

Oncol Rep. 2018 May;39(5):2209-2216. doi: 10.3892/or.2018.6293. Epub 2018 Mar 5.

PMID:
29512761
16.

Importance of Net Hydrophobicity in the Cellular Uptake of All-Hydrocarbon Stapled Peptides.

Sakagami K, Masuda T, Kawano K, Futaki S.

Mol Pharm. 2018 Mar 5;15(3):1332-1340. doi: 10.1021/acs.molpharmaceut.7b01130. Epub 2018 Feb 21.

PMID:
29420899
17.

Detection of N6-methyladenosine based on the methyl-sensitivity of MazF RNA endonuclease.

Imanishi M, Tsuji S, Suda A, Futaki S.

Chem Commun (Camb). 2017 Nov 30;53(96):12930-12933. doi: 10.1039/c7cc07699a.

PMID:
29154383
18.

Nested PUF Proteins: Extending Target RNA Elements for Gene Regulation.

Shinoda K, Tsuji S, Futaki S, Imanishi M.

Chembiochem. 2018 Jan 18;19(2):171-176. doi: 10.1002/cbic.201700458. Epub 2017 Dec 18.

PMID:
29110405
19.

Increased Hydrophobic Block Length of PTDMs Promotes Protein Internalization.

Backlund CM, Sgolastra F, Otter R, Minter L, Takeuchi T, Futaki S, Tew GN.

Polym Chem. 2016 Dec 28;7(48):7514-7521. doi: 10.1039/C6PY01615D. Epub 2016 Nov 14.

20.

Cell-Surface Interactions on Arginine-Rich Cell-Penetrating Peptides Allow for Multiplex Modes of Internalization.

Futaki S, Nakase I.

Acc Chem Res. 2017 Oct 17;50(10):2449-2456. doi: 10.1021/acs.accounts.7b00221. Epub 2017 Sep 14.

PMID:
28910080
21.

Cytosolic antibody delivery by lipid-sensitive endosomolytic peptide.

Akishiba M, Takeuchi T, Kawaguchi Y, Sakamoto K, Yu HH, Nakase I, Takatani-Nakase T, Madani F, Gräslund A, Futaki S.

Nat Chem. 2017 Aug;9(8):751-761. doi: 10.1038/nchem.2779. Epub 2017 May 22.

PMID:
28754944
22.

Complete right- and left-sided thoracic ducts associated with aberrant left vertebral artery: unreported case with surgical implications.

Eid N, Ito Y, Futaki S, Kondo Y.

Folia Morphol (Warsz). 2018;77(1):156-160. doi: 10.5603/FM.a2017.0055. Epub 2017 Jun 27.

23.

Three-dimensional cell shapes and arrangements in human sweat glands as revealed by whole-mount immunostaining.

Kurata R, Futaki S, Nakano I, Fujita F, Tanemura A, Murota H, Katayama I, Okada F, Sekiguchi K.

PLoS One. 2017 Jun 21;12(6):e0178709. doi: 10.1371/journal.pone.0178709. eCollection 2017.

24.

Loosening of Lipid Packing Promotes Oligoarginine Entry into Cells.

Murayama T, Masuda T, Afonin S, Kawano K, Takatani-Nakase T, Ida H, Takahashi Y, Fukuma T, Ulrich AS, Futaki S.

Angew Chem Int Ed Engl. 2017 Jun 19;56(26):7644-7647. doi: 10.1002/anie.201703578.

PMID:
28597524
25.

Arginine-rich cell-penetrating peptide-modified extracellular vesicles for active macropinocytosis induction and efficient intracellular delivery.

Nakase I, Noguchi K, Aoki A, Takatani-Nakase T, Fujii I, Futaki S.

Sci Rep. 2017 May 16;7(1):1991. doi: 10.1038/s41598-017-02014-6.

26.

Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling.

Morooka N, Futaki S, Sato-Nishiuchi R, Nishino M, Totani Y, Shimono C, Nakano I, Nakajima H, Mochizuki N, Sekiguchi K.

Circ Res. 2017 Apr 14;120(8):1276-1288. doi: 10.1161/CIRCRESAHA.116.308825. Epub 2017 Feb 8.

PMID:
28179430
27.

[Membrane translocation of arginine-rich cell-penetrating peptides].

Futaki S.

Seikagaku. 2017 Feb;89(1):8-14. Review. Japanese. No abstract available.

PMID:
29624359
28.

Sequence-specific recognition of methylated DNA by an engineered transcription activator-like effector protein.

Tsuji S, Futaki S, Imanishi M.

Chem Commun (Camb). 2016 Dec 6;52(99):14238-14241.

PMID:
27872906
29.

Receptor clustering and activation by multivalent interaction through recognition peptides presented on exosomes.

Nakase I, Ueno N, Katayama M, Noguchi K, Takatani-Nakase T, Kobayashi NB, Yoshida T, Fujii I, Futaki S.

Chem Commun (Camb). 2016 Dec 22;53(2):317-320. doi: 10.1039/c6cc06719k.

PMID:
27853769
30.

Cholesterol-Lowering Effect of Octaarginine-Appended β-Cyclodextrin in Npc1-Trap-CHO Cells.

Motoyama K, Nishiyama R, Maeda Y, Higashi T, Kawaguchi Y, Futaki S, Ishitsuka Y, Kondo Y, Irie T, Era T, Arima H.

Biol Pharm Bull. 2016 Nov 1;39(11):1823-1829. Epub 2016 Sep 6.

31.
32.
33.

Calmodulin EF-hand peptides as Ca2+ -switchable recognition tags.

Oku A, Imanishi M, Noshiro D, Murayama T, Takeuchi T, Nakase I, Futaki S.

Biopolymers. 2017 Jan;108(1). doi: 10.1002/bip.22937.

PMID:
27554421
34.
35.

Relating structure and internalization for ROMP-based protein mimics.

Backlund CM, Takeuchi T, Futaki S, Tew GN.

Biochim Biophys Acta. 2016 Jul;1858(7 Pt A):1443-50. doi: 10.1016/j.bbamem.2016.03.024. Epub 2016 Mar 31.

36.

Syndecan-4 Is a Receptor for Clathrin-Mediated Endocytosis of Arginine-Rich Cell-Penetrating Peptides.

Kawaguchi Y, Takeuchi T, Kuwata K, Chiba J, Hatanaka Y, Nakase I, Futaki S.

Bioconjug Chem. 2016 Apr 20;27(4):1119-30. doi: 10.1021/acs.bioconjchem.6b00082. Epub 2016 Apr 5.

PMID:
27019270
37.

Preparation of peptide thioesters from naturally occurring sequences using reaction sequence consisting of regioselective S-cyanylation and hydrazinolysis.

Miyajima R, Tsuda Y, Inokuma T, Shigenaga A, Imanishi M, Futaki S, Otaka A.

Biopolymers. 2016 Nov 4;106(4):531-46. doi: 10.1002/bip.22757.

PMID:
26501985
38.

Suppressive effect of membrane-permeable peptides derived from autophosphorylation sites of the IGF-1 receptor on breast cancer cells.

Kuroda Y, Kato-Kogoe N, Tasaki E, Yuasa-Sunagawa M, Yamanegi K, Nakasho K, Nakase I, Futaki S, Tohyama Y, Hirose M.

Eur J Pharmacol. 2015 Oct 15;765:24-33. doi: 10.1016/j.ejphar.2015.08.004. Epub 2015 Aug 12. Erratum in: Eur J Pharmacol. 2015 Nov 15;767:220. Nakase, Ikuhiko [corrected to Nakasho, Ikuhiko].

PMID:
26276395
39.

Cell Penetrating Peptides for Chemical Biological Studies.

Nakase I, Takeuchi T, Futaki S.

Methods Mol Biol. 2015;1324:387-96. doi: 10.1007/978-1-4939-2806-4_26.

PMID:
26202284
40.
41.

Intercellular chaperone transmission via exosomes contributes to maintenance of protein homeostasis at the organismal level.

Takeuchi T, Suzuki M, Fujikake N, Popiel HA, Kikuchi H, Futaki S, Wada K, Nagai Y.

Proc Natl Acad Sci U S A. 2015 May 12;112(19):E2497-506. doi: 10.1073/pnas.1412651112. Epub 2015 Apr 27.

42.

Peripheral circulation evaluation with near-infrared spectroscopy in skeletal muscle during cardiopulmonary bypass.

Mukaida H, Matsushita S, Inotani T, Futaki S, Takano A, Watanabe M, Morita T, Miida T, Amano A.

Perfusion. 2015 Nov;30(8):653-9. doi: 10.1177/0267659115575419. Epub 2015 Feb 26.

PMID:
25721457
43.

Isolation and characterization of sweat gland myoepithelial cells from human skin.

Kurata R, Futaki S, Nakano I, Tanemura A, Murota H, Katayama I, Sekiguchi K.

Cell Struct Funct. 2014;39(2):101-12. Epub 2014 Sep 5.

44.

Controlling leucine-zipper partner recognition in cells through modification of a-g interactions.

Azuma Y, Kükenshöner T, Ma G, Yasunaga J, Imanishi M, Tanaka G, Nakase I, Maruno T, Kobayashi Y, Arndt KM, Matsuoka M, Futaki S.

Chem Commun (Camb). 2014 Jun 18;50(48):6364-7. doi: 10.1039/c4cc00555d.

PMID:
24803110
45.

[Life-oriented chemistry in pharmaceutical sciences: chemistry challenge to mystery of life].

Sasaki S, Futaki S.

Yakugaku Zasshi. 2014;134(4):499-500. Japanese. No abstract available.

46.

Molecular interplays involved in the cellular uptake of octaarginine on cell surfaces and the importance of syndecan-4 cytoplasmic V domain for the activation of protein kinase Cα.

Nakase I, Osaki K, Tanaka G, Utani A, Futaki S.

Biochem Biophys Res Commun. 2014 Apr 18;446(4):857-62. doi: 10.1016/j.bbrc.2014.03.018. Epub 2014 Mar 12.

PMID:
24632200
47.

Peptide-based therapeutic approaches for treatment of the polyglutamine diseases.

Takeuchi T, Popiel HA, Futaki S, Wada K, Nagai Y.

Curr Med Chem. 2014;21(23):2575-82. Review.

PMID:
24533807
48.

Creating a TALE protein with unbiased 5'-T binding.

Tsuji S, Futaki S, Imanishi M.

Biochem Biophys Res Commun. 2013 Nov 8;441(1):262-5. doi: 10.1016/j.bbrc.2013.10.060. Epub 2013 Oct 19.

PMID:
24148249
49.

A cyclochiral conformational motif constructed using a robust hydrogen-bonding network.

Mishiro K, Furuta T, Sasamori T, Hayashi K, Tokitoh N, Futaki S, Kawabata T.

J Am Chem Soc. 2013 Sep 18;135(37):13644-7. doi: 10.1021/ja407051k. Epub 2013 Sep 9. Erratum in: J Am Chem Soc. 2013 Nov 13;135(45):17236.

PMID:
24007282
50.

Development of a novel nanoparticle by dual modification with the pluripotential cell-penetrating peptide PepFect6 for cellular uptake, endosomal escape, and decondensation of an siRNA core complex.

Mitsueda A, Shimatani Y, Ito M, Ohgita T, Yamada A, Hama S, Gräslund A, Lindberg S, Langel Ü, Harashima H, Nakase I, Futaki S, Kogure K.

Biopolymers. 2013 Nov;100(6):698-704. doi: 10.1002/bip.22310.

PMID:
23893316

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