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Items: 14

1.

Prediction of off-target activities for the end-to-end design of CRISPR guide RNAs.

Listgarten J, Weinstein M, Kleinstiver BP, Sousa AA, Joung JK, Crawford J, Gao K, Hoang L, Elibol M, Doench JG, Fusi N.

Nat Biomed Eng. 2018 Jan;2(1):38-47. doi: 10.1038/s41551-017-0178-6. Epub 2018 Jan 10.

2.

Orthologous CRISPR-Cas9 enzymes for combinatorial genetic screens.

Najm FJ, Strand C, Donovan KF, Hegde M, Sanson KR, Vaimberg EW, Sullender ME, Hartenian E, Kalani Z, Fusi N, Listgarten J, Younger ST, Bernstein BE, Root DE, Doench JG.

Nat Biotechnol. 2018 Feb;36(2):179-189. doi: 10.1038/nbt.4048. Epub 2017 Dec 18.

3.

Flexible Modeling of Genetic Effects on Function-Valued Traits.

Fusi N, Listgarten J.

J Comput Biol. 2017 Jun;24(6):524-535. doi: 10.1089/cmb.2016.0174. Epub 2017 Jan 5.

PMID:
28056190
4.

Impact of pre-adapted HIV transmission.

Carlson JM, Du VY, Pfeifer N, Bansal A, Tan VY, Power K, Brumme CJ, Kreimer A, DeZiel CE, Fusi N, Schaefer M, Brockman MA, Gilmour J, Price MA, Kilembe W, Haubrich R, John M, Mallal S, Shapiro R, Frater J, Harrigan PR, Ndung'u T, Allen S, Heckerman D, Sidney J, Allen TM, Goulder PJ, Brumme ZL, Hunter E, Goepfert PA.

Nat Med. 2016 Jun;22(6):606-13. doi: 10.1038/nm.4100. Epub 2016 May 16.

5.

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9.

Doench JG, Fusi N, Sullender M, Hegde M, Vaimberg EW, Donovan KF, Smith I, Tothova Z, Wilen C, Orchard R, Virgin HW, Listgarten J, Root DE.

Nat Biotechnol. 2016 Feb;34(2):184-191. doi: 10.1038/nbt.3437. Epub 2016 Jan 18.

6.

Further improvements to linear mixed models for genome-wide association studies.

Widmer C, Lippert C, Weissbrod O, Fusi N, Kadie C, Davidson R, Listgarten J, Heckerman D.

Sci Rep. 2014 Nov 12;4:6874. doi: 10.1038/srep06874.

7.

Warped linear mixed models for the genetic analysis of transformed phenotypes.

Fusi N, Lippert C, Lawrence ND, Stegle O.

Nat Commun. 2014 Sep 19;5:4890. doi: 10.1038/ncomms5890.

8.

A genome-to-genome analysis of associations between human genetic variation, HIV-1 sequence diversity, and viral control.

Bartha I, Carlson JM, Brumme CJ, McLaren PJ, Brumme ZL, John M, Haas DW, Martinez-Picado J, Dalmau J, López-Galíndez C, Casado C, Rauch A, Günthard HF, Bernasconi E, Vernazza P, Klimkait T, Yerly S, O'Brien SJ, Listgarten J, Pfeifer N, Lippert C, Fusi N, Kutalik Z, Allen TM, Müller V, Harrigan PR, Heckerman D, Telenti A, Fellay J.

Elife. 2013 Oct 29;2:e01123. doi: 10.7554/eLife.01123.

9.

Transcriptomic indices of fast and slow disease progression in two mouse models of amyotrophic lateral sclerosis.

Nardo G, Iennaco R, Fusi N, Heath PR, Marino M, Trolese MC, Ferraiuolo L, Lawrence N, Shaw PJ, Bendotti C.

Brain. 2013 Nov;136(Pt 11):3305-32. doi: 10.1093/brain/awt250. Epub 2013 Sep 24.

PMID:
24065725
10.

Detecting regulatory gene-environment interactions with unmeasured environmental factors.

Fusi N, Lippert C, Borgwardt K, Lawrence ND, Stegle O.

Bioinformatics. 2013 Jun 1;29(11):1382-9. doi: 10.1093/bioinformatics/btt148. Epub 2013 Apr 4.

PMID:
23559640
11.

Unravelling the enigma of selective vulnerability in neurodegeneration: motor neurons resistant to degeneration in ALS show distinct gene expression characteristics and decreased susceptibility to excitotoxicity.

Brockington A, Ning K, Heath PR, Wood E, Kirby J, Fusi N, Lawrence N, Wharton SB, Ince PG, Shaw PJ.

Acta Neuropathol. 2013 Jan;125(1):95-109. doi: 10.1007/s00401-012-1058-5. Epub 2012 Nov 13.

12.

Joint modelling of confounding factors and prominent genetic regulators provides increased accuracy in genetical genomics studies.

Fusi N, Stegle O, Lawrence ND.

PLoS Comput Biol. 2012 Jan;8(1):e1002330. doi: 10.1371/journal.pcbi.1002330. Epub 2012 Jan 5.

13.

[Preliminary studies of the earliness of first newborn-mother contact and breast feeding after dismissal from the hospital].

Zuppa AA, Fusi N, Palumbo A, Tortorolo G.

Minerva Pediatr. 1982 Oct 31;34(20):841-4. Italian. No abstract available.

PMID:
7155092
14.

[Social-cultural and pre-perinatal factors influencing the course of breast-feeding (author's transl)].

Zuppa AA, Fusi N, Clemente A, Romagnoli C, Tortorolo G.

Pediatr Med Chir. 1981 Sep-Oct;3(5):369-76. Review. Italian. No abstract available.

PMID:
7045824

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