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Prevalence of and risk factors for cerebral microbleeds in a general Japanese elderly community.

Yubi T, Hata J, Ohara T, Mukai N, Hirakawa Y, Yoshida D, Gotoh S, Hirabayashi N, Furuta Y, Ago T, Kitazono T, Kiyohara Y, Ninomiya T.

Neurol Clin Pract. 2018 Jun;8(3):223-231. doi: 10.1212/CPJ.0000000000000464.


Pre-operative autologous blood donation and transfusion-related adverse reactions: A 14-year experience at a university hospital.

Furuta Y, Nakamura Y, Tokida M, Ichikawa K, Ohsawa T, Ohkubo M, Ohsaka A.

Transfus Apher Sci. 2018 Aug 1. pii: S1473-0502(18)30248-9. doi: 10.1016/j.transci.2018.07.016. [Epub ahead of print]


Nonoperative management of blunt liver injury in hemodynamically stable versus unstable patients: a retrospective study.

Inukai K, Uehara S, Furuta Y, Miura M.

Emerg Radiol. 2018 Jul 19. doi: 10.1007/s10140-018-1627-6. [Epub ahead of print]


Favipiravir (T-705) but not ribavirin is effective against two distinct strains of Crimean-Congo hemorrhagic fever virus in mice.

Hawman DW, Haddock E, Meade-White K, Williamson B, Hanley PW, Rosenke K, Komeno T, Furuta Y, Gowen BB, Feldmann H.

Antiviral Res. 2018 Sep;157:18-26. doi: 10.1016/j.antiviral.2018.06.013. Epub 2018 Jun 21.


Development of a Novel Human Parathyroid Hormone Receptor 1 (hPTHR1) Agonist (CH5447240), a Potent and Orally Available Small Molecule for Treatment of Hypoparathyroidism.

Nishimura Y, Esaki T, Isshiki Y, Okamoto N, Furuta Y, Kotake T, Watanabe Y, Ohta M, Nakagawa T, Noda H, Shimizu M, Saito H, Tamura T, Sato H.

J Med Chem. 2018 Jul 3. doi: 10.1021/acs.jmedchem.8b00182. [Epub ahead of print]


Rapid Sintering of Li₂O-Nb₂O₅-TiO₂ Solid Solution by Air Pressure Control and Clarification of Its Mechanism.

Nakano H, Kamimoto K, Yamamoto T, Furuta Y.

Materials (Basel). 2018 Jun 11;11(6). pii: E987. doi: 10.3390/ma11060987.


Use of Favipiravir to Treat Lassa Virus Infection in Macaques.

Rosenke K, Feldmann H, Westover JB, Hanley PW, Martellaro C, Feldmann F, Saturday G, Lovaglio J, Scott DP, Furuta Y, Komeno T, Gowen BB, Safronetz D.

Emerg Infect Dis. 2018 Sep 17;24(9). doi: 10.3201/eid2409.180233. [Epub ahead of print]


Favipiravir (T-705) protects against Nipah virus infection in the hamster model.

Dawes BE, Kalveram B, Ikegami T, Juelich T, Smith JK, Zhang L, Park A, Lee B, Komeno T, Furuta Y, Freiberg AN.

Sci Rep. 2018 May 15;8(1):7604. doi: 10.1038/s41598-018-25780-3.


Effective Treatment of Experimental Lymphocytic Choriomeningitis Virus Infection: Consideration of Favipiravir for Use With Infected Organ Transplant Recipients.

Hickerson BT, Westover JB, Jung KH, Komeno T, Furuta Y, Gowen BB.

J Infect Dis. 2018 Jul 13;218(4):522-527. doi: 10.1093/infdis/jiy159.


Secular trends in the incidence, risk factors, and prognosis of transient ischemic attack in Japan: The Hisayama Study.

Furuta Y, Hata J, Mukai N, Hirakawa Y, Ago T, Kitazono T, Kiyohara Y, Ninomiya T.

Atherosclerosis. 2018 Jun;273:84-90. doi: 10.1016/j.atherosclerosis.2018.04.010. Epub 2018 Apr 12.


Usefulness of BCOR gene mutation as a prognostic factor in acute myeloid leukemia with intermediate cytogenetic prognosis.

Terada K, Yamaguchi H, Ueki T, Usuki K, Kobayashi Y, Tajika K, Gomi S, Kurosawa S, Saito R, Furuta Y, Miyadera K, Tokura T, Marumo A, Omori I, Sakaguchi M, Fujiwara Y, Yui S, Ryotokuji T, Arai K, Kitano T, Wakita S, Fukuda T, Inokuchi K.

Genes Chromosomes Cancer. 2018 Aug;57(8):401-408. doi: 10.1002/gcc.22542.


Animal transgenesis on the fast track in the era of evolving genome editing technologies: report for TT2017 the 14th Transgenic Technology Meeting in Snowbird, Utah.

Furuta Y, Kiyonari H.

Transgenic Res. 2018 Feb;27(1):123-129. doi: 10.1007/s11248-018-0060-7. Epub 2018 Feb 3. No abstract available.


Ribosome Incorporation into Somatic Cells Promotes Lineage Transdifferentiation towards Multipotency.

Ito N, Katoh K, Kushige H, Saito Y, Umemoto T, Matsuzaki Y, Kiyonari H, Kobayashi D, Soga M, Era T, Araki N, Furuta Y, Suda T, Kida Y, Ohta K.

Sci Rep. 2018 Jan 26;8(1):1634. doi: 10.1038/s41598-018-20057-1.


Cell Type-Specific Survey of Epigenetic Modifications by Tandem Chromatin Immunoprecipitation Sequencing.

Mito M, Kadota M, Tanaka K, Furuta Y, Abe K, Iwasaki S, Nakagawa S.

Sci Rep. 2018 Jan 18;8(1):1143. doi: 10.1038/s41598-018-19494-9.


Photonuclear reactions triggered by lightning discharge.

Enoto T, Wada Y, Furuta Y, Nakazawa K, Yuasa T, Okuda K, Makishima K, Sato M, Sato Y, Nakano T, Umemoto D, Tsuchiya H.

Nature. 2017 Nov 22;551(7681):481-484. doi: 10.1038/nature24630.


Regulation of continuous but complex expression pattern of Six1 during early sensory development.

Sato S, Furuta Y, Kawakami K.

Dev Dyn. 2018 Jan;247(1):250-261. doi: 10.1002/dvdy.24603. Epub 2017 Nov 30.


Factors affecting the effect of physical rehabilitation therapy for synkinesis as a sequela to facial nerve palsy.

Fujiwara K, Furuta Y, Yamamoto N, Katoh K, Fukuda S.

Auris Nasus Larynx. 2018 Aug;45(4):732-739. doi: 10.1016/j.anl.2017.10.003.


Radiation therapy versus surgery for patients with cervical squamous cell carcinoma who have undergone neoadjuvant chemotherapy revisited.

Furuta Y, Todo Y, Yamazaki H, Shimada C, Takeshita S, Okamoto K, Kato H.

Int J Clin Oncol. 2018 Feb;23(1):126-133. doi: 10.1007/s10147-017-1191-1. Epub 2017 Sep 19.


Impact of low coagulation factor XIII activity in patients with chronic subdural hematoma associated with cerebrospinal fluid hypovolemia: A retrospective study.

Shimogawa T, Morioka T, Sayama T, Akiyama T, Haga S, Amano T, Furuta Y, Murao K, Arakawa S, Takeshita I.

Surg Neurol Int. 2017 Aug 14;8:192. doi: 10.4103/sni.sni_82_17. eCollection 2017.


Heartland virus infection in hamsters deficient in type I interferon signaling: Protracted disease course ameliorated by favipiravir.

Westover JB, Rigas JD, Van Wettere AJ, Li R, Hickerson BT, Jung KH, Miao J, Reynolds ES, Conrad BL, Nielson S, Furuta Y, Thangamani S, Wang Z, Gowen BB.

Virology. 2017 Nov;511:175-183. doi: 10.1016/j.virol.2017.08.004. Epub 2017 Aug 31.


Characteristics of activated carbon remove sulfur particles against smog.

Ge S, Liu Z, Furuta Y, Peng W.

Saudi J Biol Sci. 2017 Sep;24(6):1370-1374. doi: 10.1016/j.sjbs.2016.12.016. Epub 2016 Dec 24.


Adsorption characteristics of sulfur solution by acticarbon against drinking-water toxicosis.

Ge S, Liu Z, Furuta Y, Peng W.

Saudi J Biol Sci. 2017 Sep;24(6):1355-1360. doi: 10.1016/j.sjbs.2016.09.010. Epub 2016 Sep 9.


The effects of quality of life on behavioral and psychological symptoms in elderly people with dementia residing at long-term care facilities.

Suzuki M, Hattori H, Fukuda K, Ooshiro H, Saruhara T, Furuta Y, Abe K, Kanamori M.

Nihon Ronen Igakkai Zasshi. 2017;54(3):392-402. doi: 10.3143/geriatrics.54.392. Japanese.


Lethality of MalE-LacZ hybrid protein shares mechanistic attributes with oxidative component of antibiotic lethality.

Takahashi N, Gruber CC, Yang JH, Liu X, Braff D, Yashaswini CN, Bhubhanil S, Furuta Y, Andreescu S, Collins JJ, Walker GC.

Proc Natl Acad Sci U S A. 2017 Aug 9. pii: 201707466. doi: 10.1073/pnas.1707466114. [Epub ahead of print]


Enhanced protection against experimental Junin virus infection through the use of a modified favipiravir loading dose strategy.

Gowen BB, Westover JB, Sefing EJ, Van Wettere AJ, Bailey KW, Wandersee L, Komeno T, Furuta Y.

Antiviral Res. 2017 Sep;145:131-135. doi: 10.1016/j.antiviral.2017.07.019. Epub 2017 Aug 2.


Favipiravir (T-705), a broad spectrum inhibitor of viral RNA polymerase.

Furuta Y, Komeno T, Nakamura T.

Proc Jpn Acad Ser B Phys Biol Sci. 2017;93(7):449-463. doi: 10.2183/pjab.93.027. Review.


Apical constriction in distal visceral endoderm cells initiates global, collective cell rearrangement in embryonic visceral endoderm to form anterior visceral endoderm.

Shioi G, Hoshino H, Abe T, Kiyonari H, Nakao K, Meng W, Furuta Y, Fujimori T, Aizawa S.

Dev Biol. 2017 Sep 1;429(1):20-30. doi: 10.1016/j.ydbio.2017.07.004. Epub 2017 Jul 14.


Dynamical transition in a jammed state of a quasi-two-dimensional foam.

Kurita R, Furuta Y, Yanagisawa N, Oikawa N.

Phys Rev E. 2017 Jun;95(6-1):062613. doi: 10.1103/PhysRevE.95.062613. Epub 2017 Jun 30.


Smad4 is essential for directional progression from committed neural progenitor cells through neuronal differentiation in the postnatal mouse brain.

Kawaguchi-Niida M, Shibata N, Furuta Y.

Mol Cell Neurosci. 2017 Sep;83:55-64. doi: 10.1016/j.mcn.2017.06.008. Epub 2017 Jun 29.


Prognostic factors for patients with brain metastasis from gynecological cancer: a significance of treatment-free interval of more than 6 months.

Takeshita S, Todo Y, Furuta Y, Okamoto K, Minobe S, Yamashiro K, Kato H.

Jpn J Clin Oncol. 2017 Jul 1;47(7):604-610. doi: 10.1093/jjco/hyx047.


MTCL1 plays an essential role in maintaining Purkinje neuron axon initial segment.

Satake T, Yamashita K, Hayashi K, Miyatake S, Tamura-Nakano M, Doi H, Furuta Y, Shioi G, Miura E, Takeo YH, Yoshida K, Yahikozawa H, Matsumoto N, Yuzaki M, Suzuki A.

EMBO J. 2017 May 2;36(9):1227-1242. doi: 10.15252/embj.201695630. Epub 2017 Mar 10.


Fungal ITS1 Deep-Sequencing Strategies to Reconstruct the Composition of a 26-Species Community and Evaluation of the Gut Mycobiota of Healthy Japanese Individuals.

Motooka D, Fujimoto K, Tanaka R, Yaguchi T, Gotoh K, Maeda Y, Furuta Y, Kurakawa T, Goto N, Yasunaga T, Narazaki M, Kumanogoh A, Horii T, Iida T, Takeda K, Nakamura S.

Front Microbiol. 2017 Feb 15;8:238. doi: 10.3389/fmicb.2017.00238. eCollection 2017.


Sterol regulatory element-binding protein-1c orchestrates metabolic remodeling of white adipose tissue by caloric restriction.

Fujii N, Narita T, Okita N, Kobayashi M, Furuta Y, Chujo Y, Sakai M, Yamada A, Takeda K, Konishi T, Sudo Y, Shimokawa I, Higami Y.

Aging Cell. 2017 Jun;16(3):508-517. doi: 10.1111/acel.12576. Epub 2017 Mar 3.


E-NPP3 controls plasmacytoid dendritic cell numbers in the small intestine.

Furuta Y, Tsai SH, Kinoshita M, Fujimoto K, Okumura R, Umemoto E, Kurashima Y, Kiyono H, Kayama H, Takeda K.

PLoS One. 2017 Feb 22;12(2):e0172509. doi: 10.1371/journal.pone.0172509. eCollection 2017.


Cerebral Venous Thrombosis in the Superior Sagittal Sinus as a Rare Cause of a Paroxysmal Kinetic Tremor.

Murao K, Arakawa S, Furuta Y, Shijo M, Ago T, Kitazono T.

Case Rep Neurol. 2017 Jan 3;8(3):276-281. doi: 10.1159/000455022. eCollection 2016 Sep-Dec.


Toll-like receptor 4 antagonist TAK-242 inhibits autoinflammatory symptoms in DITRA.

Shibata A, Sugiura K, Furuta Y, Mukumoto Y, Kaminuma O, Akiyama M.

J Autoimmun. 2017 Jun;80:28-38. doi: 10.1016/j.jaut.2017.01.007. Epub 2017 Feb 11.


Restriction glycosylases: involvement of endonuclease activities in the restriction process.

Zhang Y, Matsuzaka T, Yano H, Furuta Y, Nakano T, Ishikawa K, Fukuyo M, Takahashi N, Suzuki Y, Sugano S, Ide H, Kobayashi I.

Nucleic Acids Res. 2017 Feb 17;45(3):1392-1403. doi: 10.1093/nar/gkw1250.


Signal changes on magnetic resonance perfusion images with arterial spin labeling after carotid endarterectomy.

Shimogawa T, Morioka T, Sayama T, Haga S, Akiyama T, Murao K, Kanazawa Y, Furuta Y, Sakata A, Arakawa S.

Surg Neurol Int. 2016 Dec 21;7(Suppl 41):S1031-S1040. doi: 10.4103/2152-7806.196322. eCollection 2016.


Persistent fibroblast growth factor 23 signalling in the parathyroid glands for secondary hyperparathyroidism in mice with chronic kidney disease.

Kawakami K, Takeshita A, Furushima K, Miyajima M, Hatamura I, Kuro-O M, Furuta Y, Sakaguchi K.

Sci Rep. 2017 Jan 17;7:40534. doi: 10.1038/srep40534.


Desulphurization characteristics of bamboo charcoal from sulfur solution.

Ge S, Liu Z, Li R, Furuta Y, Peng W.

Saudi J Biol Sci. 2017 Jan;24(1):127-131. doi: 10.1016/j.sjbs.2016.09.005. Epub 2016 Sep 22.


Adsorption characteristics of sulfur powder by bamboo charcoal to restrain sulfur allergies.

Peng W, Ge S, Liu Z, Furuta Y.

Saudi J Biol Sci. 2017 Jan;24(1):103-107. doi: 10.1016/j.sjbs.2016.08.013. Epub 2016 Sep 20.


Modeling Severe Fever with Thrombocytopenia Syndrome Virus Infection in Golden Syrian Hamsters: Importance of STAT2 in Preventing Disease and Effective Treatment with Favipiravir.

Gowen BB, Westover JB, Miao J, Van Wettere AJ, Rigas JD, Hickerson BT, Jung KH, Li R, Conrad BL, Nielson S, Furuta Y, Wang Z.

J Virol. 2017 Jan 18;91(3). pii: e01942-16. doi: 10.1128/JVI.01942-16. Print 2017 Feb 1.


Close relationship between a dry-wet transition and a bubble rearrangement in two-dimensional foam.

Furuta Y, Oikawa N, Kurita R.

Sci Rep. 2016 Nov 22;6:37506. doi: 10.1038/srep37506.


Dysbiosis Contributes to Arthritis Development via Activation of Autoreactive T Cells in the Intestine.

Maeda Y, Kurakawa T, Umemoto E, Motooka D, Ito Y, Gotoh K, Hirota K, Matsushita M, Furuta Y, Narazaki M, Sakaguchi N, Kayama H, Nakamura S, Iida T, Saeki Y, Kumanogoh A, Sakaguchi S, Takeda K.

Arthritis Rheumatol. 2016 Nov;68(11):2646-2661. doi: 10.1002/art.39783.


Coordinately Co-opted Multiple Transposable Elements Constitute an Enhancer for wnt5a Expression in the Mammalian Secondary Palate.

Nishihara H, Kobayashi N, Kimura-Yoshida C, Yan K, Bormuth O, Ding Q, Nakanishi A, Sasaki T, Hirakawa M, Sumiyama K, Furuta Y, Tarabykin V, Matsuo I, Okada N.

PLoS Genet. 2016 Oct 14;12(10):e1006380. doi: 10.1371/journal.pgen.1006380. eCollection 2016 Oct.


Portable, On-Demand Biomolecular Manufacturing.

Pardee K, Slomovic S, Nguyen PQ, Lee JW, Donghia N, Burrill D, Ferrante T, McSorley FR, Furuta Y, Vernet A, Lewandowski M, Boddy CN, Joshi NS, Collins JJ.

Cell. 2016 Sep 22;167(1):248-259.e12. doi: 10.1016/j.cell.2016.09.013.


Humanized mouse as an appropriate model for accelerated global HIV research and vaccine development: current trend.

Ibeh BO, Furuta Y, Habu JB, Ogbadu L.

Immunopharmacol Immunotoxicol. 2016 Sep 23:1-13. [Epub ahead of print]


Population Evolution of Helicobacter pylori through Diversification in DNA Methylation and Interstrain Sequence Homogenization.

Kojima KK, Furuta Y, Yahara K, Fukuyo M, Shiwa Y, Nishiumi S, Yoshida M, Azuma T, Yoshikawa H, Kobayashi I.

Mol Biol Evol. 2016 Nov;33(11):2848-2859. Epub 2016 Sep 7.


Association Between Diabetes and Hippocampal Atrophy in Elderly Japanese: The Hisayama Study.

Hirabayashi N, Hata J, Ohara T, Mukai N, Nagata M, Shibata M, Gotoh S, Furuta Y, Yamashita F, Yoshihara K, Kitazono T, Sudo N, Kiyohara Y, Ninomiya T.

Diabetes Care. 2016 Sep;39(9):1543-9. doi: 10.2337/dc15-2800. Epub 2016 Jul 6.


Regulation of intestinal homeostasis by the ulcerative colitis-associated gene RNF186.

Fujimoto K, Kinoshita M, Tanaka H, Okuzaki D, Shimada Y, Kayama H, Okumura R, Furuta Y, Narazaki M, Tamura A, Hatakeyama S, Ikawa M, Tsuchiya K, Watanabe M, Kumanogoh A, Tsukita S, Takeda K.

Mucosal Immunol. 2017 Mar;10(2):446-459. doi: 10.1038/mi.2016.58. Epub 2016 Jul 6.


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