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Tsamadou C, Fürst D, Wang T, He N, Lee SJ, Spellman SR, Fleischhauer K, Hsu KC, Paczesny S, Verneris MR, Schrezenmeier H, Mytilineos J.

Biol Blood Marrow Transplant. 2019 Aug 16. pii: S1083-8791(19)30521-X. doi: 10.1016/j.bbmt.2019.08.007. [Epub ahead of print]


Myeloablation followed by autologous stem cell transplantation normalises systemic sclerosis molecular signatures.

Assassi S, Wang X, Chen G, Goldmuntz E, Keyes-Elstein L, Ying J, Wallace PK, Turner J, Zheng WJ, Pascual V, Varga J, Hinchcliff ME, Bellocchi C, McSweeney P, Furst DE, Nash RA, Crofford LJ, Welch B, Pinckney A, Mayes MD, Sullivan KM.

Ann Rheum Dis. 2019 Aug 7. pii: annrheumdis-2019-215770. doi: 10.1136/annrheumdis-2019-215770. [Epub ahead of print]


Abatacept in Early Diffuse Cutaneous Systemic Sclerosis - Results of a Phase 2 Investigator-Initiated, Multicenter, Double-Blind Randomized Placebo-Controlled Trial.

Khanna D, Spino C, Johnson S, Chung L, Whitfield M, Denton CP, Berrocal V, Franks J, Mehta B, Molitor J, Steen VD, Lafyatis R, Simms RW, Gill A, Kafaja S, Frech TM, Hsu V, Domsic RT, Pope JE, Gordon JK, Mayes MD, Schiopu E, Young A, Sandorfi N, Park J, Hant FN, Bernstein EJ, Chatterjee S, Castelino FV, Ajam A, Wang Y, Wood T, Allanore Y, Matucci-Cerinic M, Distler O, Singer O, Bush E, Fox D, Furst DE.

Arthritis Rheumatol. 2019 Jul 24. doi: 10.1002/art.41055. [Epub ahead of print]


Questioning a publication bias between industry-funded and non-industry-funded randomized controlled trials on biological and small molecule therapy for rheumatoid arthritis.

Cohen N, Lavie RG, Manor Y, Mimouni M, Furst DE, Amarilyo G.

Semin Arthritis Rheum. 2019 Jun 8. pii: S0049-0172(19)30073-3. doi: 10.1016/j.semarthrit.2019.06.006. [Epub ahead of print]


Pneumoproteins KL-6 and CCL-18 Predict Progression of Interstitial Lung Disease in Systemic Sclerosis.

Volkmann ER, Tashkin DP, Kuwana M, Li N, Roth MD, Charles J, Hant FN, Bogatkevich GS, Akter T, Kim G, Goldin J, Khanna D, Clements PJ, Furst DE, Elashoff RM, Silver RM, Assassi S.

Arthritis Rheumatol. 2019 Jun 24. doi: 10.1002/art.41020. [Epub ahead of print]


Performance of the Patient-Reported Outcomes Measurement Information System-29 in scleroderma: a Scleroderma Patient-centered Intervention Network Cohort Study.

Kwakkenbos L, Thombs BD, Khanna D, Carrier ME, Baron M, Furst DE, Gottesman K, van den Hoogen F, Malcarne VL, Mayes MD, Mouthon L, Nielson WR, Poiraudeau S, Riggs R, Sauvé M, Wigley F, Hudson M, Bartlett SJ.

Rheumatology (Oxford). 2019 Jun 5. pii: kez234. doi: 10.1093/rheumatology/kez234. [Epub ahead of print] No abstract available.


Targeting inflammatory pathways in axial spondyloarthritis.

Furst DE, Louie JS.

Arthritis Res Ther. 2019 Jun 4;21(1):135. doi: 10.1186/s13075-019-1885-z. Review.


Development of open-cell polyurethane-based bone surrogates for biomechanical testing of pedicle screws.

Hollensteiner M, Esterer B, Fürst D, Schrempf A, Augat P.

J Mech Behav Biomed Mater. 2019 Sep;97:247-253. doi: 10.1016/j.jmbbm.2019.05.038. Epub 2019 May 23.


HspB1 phosphorylation regulates its intramolecular dynamics and mechanosensitive molecular chaperone interaction with filamin C.

Collier MP, Alderson TR, de Villiers CP, Nicholls D, Gastall HY, Allison TM, Degiacomi MT, Jiang H, Mlynek G, Fürst DO, van der Ven PFM, Djinovic-Carugo K, Baldwin AJ, Watkins H, Gehmlich K, Benesch JLP.

Sci Adv. 2019 May 22;5(5):eaav8421. doi: 10.1126/sciadv.aav8421. eCollection 2019 May.


Identifying Possible Outcome Domains from Existing Outcome Measures to Inform an OMERACT Core Domain Set for Safety in Rheumatology Trials.

Klokker L, Berthelsen DB, Woodworth T, Andersen KM, Furst DE, Devoe D, Williamson PR, Suarez-Almazor ME, Strand V, Leong AL, Goel N, Boers M, Brooks PM, March L, Sloan VS, Tugwell P, Simon LS, Christensen R.

J Rheumatol. 2019 May 1. pii: jrheum.190196. doi: 10.3899/jrheum.190196. [Epub ahead of print]


Re-treatment with abatacept plus methotrexate for disease flare after complete treatment withdrawal in patients with early rheumatoid arthritis: 2-year results from the AVERT study.

Emery P, Burmester GR, Bykerk VP, Combe BG, Furst DE, Maldonado MA, Huizinga TW.

RMD Open. 2019 Feb 8;5(1):e000840. doi: 10.1136/rmdopen-2018-000840. eCollection 2019.


Study of MRI brain findings and carotid US features in systemic sclerosis patients, relationship with disease parameters.

Gamal RM, Abozaid HSM, Zidan M, Abdelmegid MAF, Abdel-Razek MR, Alsayed SA, Mourad AF, Azoz NMA, Mohram LA, Furst DE.

Arthritis Res Ther. 2019 Apr 15;21(1):95. doi: 10.1186/s13075-019-1877-z.


Timely renal transplantation for scleroderma end-stage kidney disease patients can improve outcomes and quality of life.

Woodworth TG, Furst DE.

Ann Transl Med. 2019 Feb;7(3):60. doi: 10.21037/atm.2018.12.64. No abstract available.


Gender, cholinesterase, platelet count and red cell count are main predictors of peripheral blood stem cell mobilization in healthy donors.

Fürst D, Hauber D, Reinhardt P, Schauwecker P, Bunjes D, Schulz A, Mytilineos J, Wiesneth M, Schrezenmeier H, Körper S.

Vox Sang. 2019 Apr;114(3):275-282. doi: 10.1111/vox.12754. Epub 2019 Mar 14.


A novel allele of the atypical chemokine receptor 1 (ACKR1) gene containing the nucleotide change c.126 T>G (p.42Glu) encodes a third Duffy blood group protein sequence antithetical to that encoding Fya and Fyb antigens.

Weinstock C, Mytilineos J, Bugert P, Sitzmann N, Pensel E, Schrezenmeier H, Fürst D.

Transfusion. 2019 Jun;59(6):2158-2159. doi: 10.1111/trf.15232. Epub 2019 Mar 8. No abstract available.


Rho-kinase inhibitor coupled to peptide-modified albumin carrier reduces portal pressure and increases renal perfusion in cirrhotic rats.

Klein S, Frohn F, Magdaleno F, Reker-Smit C, Schierwagen R, Schierwagen I, Uschner FE, van Dijk F, Fürst DO, Djudjaj S, Boor P, Poelstra K, Beljaars L, Trebicka J.

Sci Rep. 2019 Feb 19;9(1):2256. doi: 10.1038/s41598-019-38678-5.


Cyclophosphamide for Systemic Sclerosis-related Interstitial Lung Disease: A Comparison of Scleroderma Lung Study I and II.

Volkmann ER, Tashkin DP, Sim M, Li N, Khanna D, Roth MD, Clements PJ, Hoffmann-Vold AM, Furst DE, Kim G, Goldin J, Elashoff RM.

J Rheumatol. 2019 Feb 15. pii: jrheum.180441. doi: 10.3899/jrheum.180441. [Epub ahead of print]


Utilize lung ultrasound B-lines and KL-6 to monitor anti-MDA-5 antibody-positive clinically amyopathic dermatomyositis-associated interstitial lung disease: a case report and literature review.

Wang Y, Chen S, Lin Z, Lin J, Xie X, Lin Q, Du G, Huang X, Matucci-Cerinic M, Furst DE.

Clin Rheumatol. 2019 May;38(5):1433-1436. doi: 10.1007/s10067-019-04462-z. Epub 2019 Feb 11. Review.


Genetic and inflammatory factors associated with psoriatic arthritis: Relevance to diagnosis and management.

Furst DE, Belasco J, Louie JS.

Clin Immunol. 2019 May;202:59-75. doi: 10.1016/j.clim.2019.02.001. Epub 2019 Feb 6. Review.


Correction to: On-drug and drug-free remission by baseline symptom duration: abatacept with methotrexate in patients with early rheumatoid arthritis.

Bykerk VP, Burmester GR, Combe BG, Furst DE, Huizinga TWJ, Ahmad HA, Emery P.

Rheumatol Int. 2019 May;39(5):945. doi: 10.1007/s00296-018-4232-9.


Unmet need in rheumatology: reports from the Targeted Therapies meeting 2018.

Winthrop KL, Weinblatt ME, Crow MK, Burmester GR, Mease PJ, So AK, Bykerk V, Van Vollenhoven RF, Dougados M, Kay J, Mariette X, Sieper J, Melchers F, Cronstein BN, Shevach E, Breedfeld FC, Kalden J, Smolen JS, Furst DE.

Ann Rheum Dis. 2019 Jul;78(7):872-878. doi: 10.1136/annrheumdis-2018-214280. Epub 2019 Feb 2. Review.


Minimal Clinically Important Differences for the Modified Rodnan Skin Score: Results from the Scleroderma Lung Studies (SLS-I and SLS-II).

Khanna D, Clements PJ, Volkmann ER, Wilhalme H, Tseng CH, Furst DE, Roth MD, Distler O, Tashkin DP.

Arthritis Res Ther. 2019 Jan 16;21(1):23. doi: 10.1186/s13075-019-1809-y.


Identifying Provisional Generic Contextual Factor Domains for Clinical Trials in Rheumatology: Results from an OMERACT Initiative.

Nielsen SM, Tugwell P, de Wit MPT, Boers M, Beaton DE, Woodworth TG, Escorpizo R, Shea B, Toupin-April K, Guillemin F, Strand V, Singh JA, Kloppenburg M, Furst DE, Wells GA, Smolen JS, Veselý R, Boonen A, Storgaard H, Voshaar M, March L, Christensen R; Contextual Factors Working Group.

J Rheumatol. 2019 Jan 15. pii: jrheum.181081. doi: 10.3899/jrheum.181081. [Epub ahead of print]


Adjustment of the multi-biomarker disease activity score to account for age, sex and adiposity in patients with rheumatoid arthritis.

Curtis JR, Flake DD 2nd, Weinblatt ME, Shadick NA, Østergaard M, Hetland ML, Brahe CH, Hwang YG, Furst DE, Strand V, Etzel CJ, Pappas DA, Wang X, Hwang CC, Sasso EH, Gutin A, Hitraya E, Lanchbury JS.

Rheumatology (Oxford). 2018 Dec 24. doi: 10.1093/rheumatology/key367. [Epub ahead of print]


Bone surrogates provide authentic onlay graft fixation torques.

Hollensteiner M, Augat P, Fürst D, Schrödl F, Esterer B, Gabauer S, Schrempf A.

J Mech Behav Biomed Mater. 2019 Mar;91:159-163. doi: 10.1016/j.jmbbm.2018.12.013. Epub 2018 Dec 14.


Preliminary Validation of the Digital Ulcer Clinical Assessment Score in Systemic Sclerosis.

Bruni C, Ngcozana T, Braschi F, Pucci T, Piemonte G, Benelli L, Poli M, Suliman YA, Guiducci S, Bellando-Randone S, Balduzzi S, Grotts J, Denton CP, Rasero L, Montecucco C, Furst DE, Matucci-Cerinic M.

J Rheumatol. 2019 Jun;46(6):603-608. doi: 10.3899/jrheum.171486. Epub 2018 Nov 15.


Short-term progression of interstitial lung disease in systemic sclerosis predicts long-term survival in two independent clinical trial cohorts.

Volkmann ER, Tashkin DP, Sim M, Li N, Goldmuntz E, Keyes-Elstein L, Pinckney A, Furst DE, Clements PJ, Khanna D, Steen V, Schraufnagel DE, Arami S, Hsu V, Roth MD, Elashoff RM, Sullivan KM; SLS I and SLS II study groups.

Ann Rheum Dis. 2019 Jan;78(1):122-130. doi: 10.1136/annrheumdis-2018-213708. Epub 2018 Nov 8.


Endothelial cell mineralocorticoid receptors oppose VEGF-induced gene expression and angiogenesis.

Lother A, Deng L, Huck M, Fürst D, Kowalski J, Esser JS, Moser M, Bode C, Hein L.

J Endocrinol. 2018 Sep 1. pii: JOE-18-0494.R1. doi: 10.1530/JOE-18-0494. [Epub ahead of print]


Added value of combining methotrexate with a biological agent compared to biological monotherapy in rheumatoid arthritis patients: A systematic review and meta-analysis of randomised trials.

Tarp S, Jørgensen TS, Furst DE, Dossing A, Taylor PC, Choy EH, Suarez-Almazor ME, Lyddiatt A, Kristensen LE, Bliddal H, Christensen R.

Semin Arthritis Rheum. 2019 Jun;48(6):958-966. doi: 10.1016/j.semarthrit.2018.10.002. Epub 2018 Oct 9.


Imaging and serum biomarkers in connective tissue disease-associated interstitial lung diseases: correlation between lung ultrasound B-lines and KL-6 levels.

Wang Y, Chen S, Lin Z, Du G, Lin J, Lin Q, Xiufeng H, Zhang G, Furst DE, Gargani L, Matucci-Cerinic M.

Ann Rheum Dis. 2019 Apr;78(4):573-575. doi: 10.1136/annrheumdis-2018-214098. Epub 2018 Oct 23. No abstract available.


On-drug and drug-free remission by baseline symptom duration: abatacept with methotrexate in patients with early rheumatoid arthritis.

Bykerk VP, Burmester GR, Combe BG, Furst DE, Huizinga TWJ, Ahmad HA, Emery P.

Rheumatol Int. 2018 Dec;38(12):2225-2231. doi: 10.1007/s00296-018-4173-3. Epub 2018 Oct 20. Erratum in: Rheumatol Int. 2019 Feb 5;:.


Telomere dysfunction-related serological markers and oxidative stress markers in rheumatoid arthritis patients: correlation with diseases activity.

Gamal RM, Hammam N, Zakary MM, Abdelaziz MM, Razek MRA, Mohamed MSE, Emad Y, Elnaggar MG, Furst DE.

Clin Rheumatol. 2018 Dec;37(12):3239-3246. doi: 10.1007/s10067-018-4318-5. Epub 2018 Oct 16.


Long-Term Safety of Rituximab in Rheumatoid Arthritis: Analysis From the SUNSTONE Registry.

Winthrop KL, Saag K, Cascino MD, Pei J, John A, Jahreis A, Haselkorn T, Furst DE.

Arthritis Care Res (Hoboken). 2018 Oct 8. doi: 10.1002/acr.23781. [Epub ahead of print]


Risk Factors for Mortality and Cardiopulmonary Hospitalization in Systemic Sclerosis Patients At Risk for Pulmonary Hypertension, in the PHAROS Registry.

Hsu VM, Chung L, Hummers LK, Shah A, Simms R, Bolster M, Hant FN, Silver RM, Fischer A, Hinchcliff ME, Varga J, Goldberg AZ, Derk CT, Schiopu E, Khanna D, Shapiro LS, Domsic RT, Medsger T, Mayes MD, Furst D, Csuka ME, Molitor JA, Saketkoo LA, Salazar CR, Steen VD.

J Rheumatol. 2019 Feb;46(2):176-183. doi: 10.3899/jrheum.180018. Epub 2018 Oct 1.


Characterization of polyurethane-based synthetic vertebrae for spinal cement augmentation training.

Hollensteiner M, Botzenmayer M, Fürst D, Winkler M, Augat P, Sandriesser S, Schrödl F, Esterer B, Gabauer S, Püschel K, Schrempf A.

J Mater Sci Mater Med. 2018 Sep 29;29(10):153. doi: 10.1007/s10856-018-6161-2.


Longitudinal Changes in Quantitative Interstitial Lung Disease on Computed Tomography after Immunosuppression in the Scleroderma Lung Study II.

Goldin JG, Kim GHJ, Tseng CH, Volkmann E, Furst D, Clements P, Brown M, Roth M, Khanna D, Tashkin DP.

Ann Am Thorac Soc. 2018 Nov;15(11):1286-1295. doi: 10.1513/AnnalsATS.201802-079OC.


Vascular Leaking, a Pivotal and Early Pathogenetic Event in Systemic Sclerosis: Should the Door Be Closed?

Bruni C, Frech T, Manetti M, Rossi FW, Furst DE, De Paulis A, Rivellese F, Guiducci S, Matucci-Cerinic M, Bellando-Randone S.

Front Immunol. 2018 Sep 7;9:2045. doi: 10.3389/fimmu.2018.02045. eCollection 2018. Review.


Characterization of an artificial skull cap for cranio-maxillofacial surgery training.

Hollensteiner M, Fürst D, Augat P, Schrödl F, Esterer B, Gabauer S, Hunger S, Malek M, Stephan D, Schrempf A.

J Mater Sci Mater Med. 2018 Aug 17;29(9):135. doi: 10.1007/s10856-018-6143-4.


High-frequency ultrasound of the skin in systemic sclerosis: an exploratory study to examine correlation with disease activity and to define the minimally detectable difference.

Li H, Furst DE, Jin H, Sun C, Wang X, Yang L, He J, Wang Y, Liu A.

Arthritis Res Ther. 2018 Aug 16;20(1):181. doi: 10.1186/s13075-018-1686-9.


Procedure-Specific Validation of Artificial Vertebrae.

Hollensteiner M, Furst D, Augat P, Esterer B, Schrodl F, Gabauer S, Puschel K, Schrempf A.

IEEE Trans Biomed Eng. 2018 Aug;65(8):1852-1858. doi: 10.1109/TBME.2017.2782797. Epub 2017 Dec 13.


Sirukumab for the treatment of rheumatoid arthritis: update on sirukumab, 2018.

Bartoli F, Bae S, Cometi L, Matucci Cerinic M, Furst DE.

Expert Rev Clin Immunol. 2018 Jul;14(7):539-547. doi: 10.1080/1744666X.2018.1487291. Epub 2018 Jul 4. Review.


Remodeling of the HDL proteome with treatment response to abatacept or adalimumab in the AMPLE trial of patients with rheumatoid arthritis.

Charles-Schoeman C, Gugiu GB, Ge H, Shahbazian A, Lee YY, Wang X, Furst DE, Ranganath VK, Maldonado M, Lee T, Reddy ST.

Atherosclerosis. 2018 Aug;275:107-114. doi: 10.1016/j.atherosclerosis.2018.04.003. Epub 2018 Apr 17.


Validation of a simulator for cranial graft lift training: Face, content, and construct validity.

Hollensteiner M, Malek M, Augat P, Fürst D, Schrödl F, Hunger S, Esterer B, Gabauer S, Schrempf A.

J Craniomaxillofac Surg. 2018 Aug;46(8):1390-1394. doi: 10.1016/j.jcms.2018.05.036. Epub 2018 May 21.


The Scleroderma Patient-Centered Intervention Network Cohort: baseline clinical features and comparison with other large scleroderma cohorts.

Dougherty DH, Kwakkenbos L, Carrier ME, Salazar G, Assassi S, Baron M, Bartlett SJ, Furst DE, Gottesman K, van den Hoogen F, Malcarne VL, Mouthon L, Nielson WR, Poiraudeau S, Sauvé M, Boire G, Bruns A, Chung L, Denton C, Dunne JV, Fortin P, Frech T, Gill A, Gordon J, Herrick AL, Hinchcliff M, Hudson M, Johnson SR, Jones N, Kafaja S, Larché M, Manning J, Pope J, Spiera R, Steen V, Sutton E, Thorne C, Wilcox P, Thombs BD, Mayes MD; SPIN Investigators.

Rheumatology (Oxford). 2018 Sep 1;57(9):1623-1631. doi: 10.1093/rheumatology/key139.


pDCs in lung and skin fibrosis in a bleomycin-induced model and patients with systemic sclerosis.

Kafaja S, Valera I, Divekar AA, Saggar R, Abtin F, Furst DE, Khanna D, Singh RR.

JCI Insight. 2018 May 3;3(9). pii: 98380. doi: 10.1172/jci.insight.98380.


Practical suggestions on intravenous iloprost in Raynaud's phenomenon and digital ulcer secondary to systemic sclerosis: Systematic literature review and expert consensus.

Ingegnoli F, Schioppo T, Allanore Y, Caporali R, Colaci M, Distler O, Furst DE, Hunzelmann N, Iannone F, Khanna D, Matucci-Cerinic M.

Semin Arthritis Rheum. 2019 Feb;48(4):686-693. doi: 10.1016/j.semarthrit.2018.03.019. Epub 2018 Apr 4.


Prevalence of cardiovascular disease and major risk factors in patients with rheumatoid arthritis: a multinational cross-sectional study.

Pappas DA, Nyberg F, Kremer JM, Lampl K, Reed GW, Horne L, Ho M, Onofrei A, Malaviya AN, Rillo OL, Radominski SC, Gal J, Gibofsky A, Popkova TV, Laurindo L, Kerzberg EM, Zahora R, Pons-Estel BA, Curtis JR, Furst DE, Greenberg JD.

Clin Rheumatol. 2018 Sep;37(9):2331-2340. doi: 10.1007/s10067-018-4113-3. Epub 2018 Apr 25.


Autologous Stem-Cell Transplantation for Severe Scleroderma.

Sullivan KM, Goldmuntz EA, Furst DE.

N Engl J Med. 2018 Mar 15;378(11):1066-1067. doi: 10.1056/NEJMc1801275. No abstract available.


Ultrasound characterization of cutaneous ulcers in systemic sclerosis.

Suliman YA, Kafaja S, Fitzgerald J, Wortsman X, Grotts J, Matucci-Cerrinic M, Ranganath VK, Furst DE.

Clin Rheumatol. 2018 Jun;37(6):1555-1561. doi: 10.1007/s10067-018-3986-5. Epub 2018 Mar 10.


Factor structure and convergent validity of the Derriford Appearance Scale-24 using standard scoring versus treating 'not applicable' responses as missing data: a Scleroderma Patient-centered Intervention Network (SPIN) cohort study.

Merz EL, Kwakkenbos L, Carrier ME, Gholizadeh S, Mills SD, Fox RS, Jewett LR, Williamson H, Harcourt D, Assassi S, Furst DE, Gottesman K, Mayes MD, Moss TP, Thombs BD, Malcarne VL; SPIN Investigators.

BMJ Open. 2018 Mar 6;8(3):e018641. doi: 10.1136/bmjopen-2017-018641. Erratum in: BMJ Open. 2018 May 5;8(5):.

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