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Items: 19

1.

Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies.

Arce Vargas F, Furness AJS, Litchfield K, Joshi K, Rosenthal R, Ghorani E, Solomon I, Lesko MH, Ruef N, Roddie C, Henry JY, Spain L, Ben Aissa A, Georgiou A, Wong YNS, Smith M, Strauss D, Hayes A, Nicol D, O'Brien T, Mårtensson L, Ljungars A, Teige I, Frendéus B; TRACERx Melanoma; TRACERx Renal; TRACERx Lung consortia, Pule M, Marafioti T, Gore M, Larkin J, Turajlic S, Swanton C, Peggs KS, Quezada SA.

Cancer Cell. 2018 Apr 9;33(4):649-663.e4. doi: 10.1016/j.ccell.2018.02.010. Epub 2018 Mar 22.

2.

Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade.

Samson A, Scott KJ, Taggart D, West EJ, Wilson E, Nuovo GJ, Thomson S, Corns R, Mathew RK, Fuller MJ, Kottke TJ, Thompson JM, Ilett EJ, Cockle JV, van Hille P, Sivakumar G, Polson ES, Turnbull SJ, Appleton ES, Migneco G, Rose AS, Coffey MC, Beirne DA, Collinson FJ, Ralph C, Alan Anthoney D, Twelves CJ, Furness AJ, Quezada SA, Wurdak H, Errington-Mais F, Pandha H, Harrington KJ, Selby PJ, Vile RG, Griffin SD, Stead LF, Short SC, Melcher AA.

Sci Transl Med. 2018 Jan 3;10(422). pii: eaam7577. doi: 10.1126/scitranslmed.aam7577.

3.

Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors.

Arce Vargas F, Furness AJS, Solomon I, Joshi K, Mekkaoui L, Lesko MH, Miranda Rota E, Dahan R, Georgiou A, Sledzinska A, Ben Aissa A, Franz D, Werner Sunderland M, Wong YNS, Henry JY, O'Brien T, Nicol D, Challacombe B, Beers SA; Melanoma TRACERx Consortium; Renal TRACERx Consortium; Lung TRACERx Consortium, Turajlic S, Gore M, Larkin J, Swanton C, Chester KA, Pule M, Ravetch JV, Marafioti T, Peggs KS, Quezada SA.

Immunity. 2017 Apr 18;46(4):577-586. doi: 10.1016/j.immuni.2017.03.013. Epub 2017 Apr 11.

4.

Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA barcodes.

Bentzen AK, Marquard AM, Lyngaa R, Saini SK, Ramskov S, Donia M, Such L, Furness AJ, McGranahan N, Rosenthal R, Straten PT, Szallasi Z, Svane IM, Swanton C, Quezada SA, Jakobsen SN, Eklund AC, Hadrup SR.

Nat Biotechnol. 2016 Oct;34(10):1037-1045. doi: 10.1038/nbt.3662. Epub 2016 Aug 29.

PMID:
27571370
5.

Neoantigen heterogeneity: a key driver of immune response and sensitivity to immune checkpoint blockade?

Furness AJ, Quezada SA, Peggs KS.

Immunotherapy. 2016 Jun;8(7):763-6. doi: 10.2217/imt-2016-0064. No abstract available.

6.

Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade.

McGranahan N, Furness AJ, Rosenthal R, Ramskov S, Lyngaa R, Saini SK, Jamal-Hanjani M, Wilson GA, Birkbak NJ, Hiley CT, Watkins TB, Shafi S, Murugaesu N, Mitter R, Akarca AU, Linares J, Marafioti T, Henry JY, Van Allen EM, Miao D, Schilling B, Schadendorf D, Garraway LA, Makarov V, Rizvi NA, Snyder A, Hellmann MD, Merghoub T, Wolchok JD, Shukla SA, Wu CJ, Peggs KS, Chan TA, Hadrup SR, Quezada SA, Swanton C.

Science. 2016 Mar 25;351(6280):1463-9. doi: 10.1126/science.aaf1490. Epub 2016 Mar 3.

7.

Anti-programmed cell death-1 therapy and insulin-dependent diabetes: a case report.

Martin-Liberal J, Furness AJ, Joshi K, Peggs KS, Quezada SA, Larkin J.

Cancer Immunol Immunother. 2015 Jun;64(6):765-7. doi: 10.1007/s00262-015-1689-1. Epub 2015 Apr 1.

PMID:
25828465
8.

Benzotriazole and 5-methylbenzotriazole in recycled water, surface water and dishwashing detergents from Perth, Western Australia: analytical method development and application.

Alotaibi MD, Patterson BM, McKinley AJ, Reeder AY, Furness AJ.

Environ Sci Process Impacts. 2015 Feb;17(2):448-57. doi: 10.1039/c4em00484a.

PMID:
25564248
9.

Fate of benzotriazole and 5-methylbenzotriazole in recycled water recharged into an anaerobic aquifer: column studies.

Alotaibi MD, Patterson BM, McKinley AJ, Reeder AY, Furness AJ, Donn MJ.

Water Res. 2015 Mar 1;70:184-95. doi: 10.1016/j.watres.2014.11.040. Epub 2014 Dec 4.

PMID:
25528548
10.

Impact of tumour microenvironment and Fc receptors on the activity of immunomodulatory antibodies.

Furness AJ, Vargas FA, Peggs KS, Quezada SA.

Trends Immunol. 2014 Jul;35(7):290-8. doi: 10.1016/j.it.2014.05.002. Epub 2014 Jun 18. Review.

PMID:
24953012
11.

Lactate dehydrogenase as a selection criterion for ipilimumab treatment in metastatic melanoma.

Kelderman S, Heemskerk B, van Tinteren H, van den Brom RR, Hospers GA, van den Eertwegh AJ, Kapiteijn EW, de Groot JW, Soetekouw P, Jansen RL, Fiets E, Furness AJ, Renn A, Krzystanek M, Szallasi Z, Lorigan P, Gore ME, Schumacher TN, Haanen JB, Larkin JM, Blank CU.

Cancer Immunol Immunother. 2014 May;63(5):449-58. doi: 10.1007/s00262-014-1528-9. Epub 2014 Mar 8.

PMID:
24609989
12.

Ultra-deep T cell receptor sequencing reveals the complexity and intratumour heterogeneity of T cell clones in renal cell carcinomas.

Gerlinger M, Quezada SA, Peggs KS, Furness AJ, Fisher R, Marafioti T, Shende VH, McGranahan N, Rowan AJ, Hazell S, Hamm D, Robins HS, Pickering L, Gore M, Nicol DL, Larkin J, Swanton C.

J Pathol. 2013 Dec;231(4):424-32. doi: 10.1002/path.4284.

13.

Multiple lines of evidence to demonstrate vinyl chloride aerobic biodegradation in the vadose zone, and factors controlling rates.

Patterson BM, Aravena R, Davis GB, Furness AJ, Bastow TP, Bouchard D.

J Contam Hydrol. 2013 Oct;153:69-77. doi: 10.1016/j.jconhyd.2013.07.008. Epub 2013 Aug 13.

PMID:
23999077
14.

Soil gas carbon dioxide probe: laboratory testing and field evaluation.

Patterson BM, Furness AJ, Bastow TP.

Environ Sci Process Impacts. 2013 May;15(5):1062-9. doi: 10.1039/c3em00100h.

PMID:
23563305
15.

Fate of N-nitrosodimethylamine in recycled water after recharge into anaerobic aquifer.

Patterson BM, Pitoi MM, Furness AJ, Bastow TP, McKinley AJ.

Water Res. 2012 Mar 15;46(4):1260-72. doi: 10.1016/j.watres.2011.12.032. Epub 2011 Dec 23.

PMID:
22244272
16.

Fate of N-nitrosomorpholine in an anaerobic aquifer used for managed aquifer recharge: a column study.

Pitoi MM, Patterson BM, Furness AJ, Bastow TP, McKinley AJ.

Water Res. 2011 Apr;45(8):2550-60. doi: 10.1016/j.watres.2011.02.018. Epub 2011 Feb 19.

PMID:
21396674
17.

Behaviour and fate of nine recycled water trace organics during managed aquifer recharge in an aerobic aquifer.

Patterson BM, Shackleton M, Furness AJ, Bekele E, Pearce J, Linge KL, Busetti F, Spadek T, Toze S.

J Contam Hydrol. 2011 Mar 25;122(1-4):53-62. doi: 10.1016/j.jconhyd.2010.11.003. Epub 2010 Nov 25.

PMID:
21186066
18.

On-line groundwater velocity probe: laboratory testing and field evaluation.

Patterson BM, Annable MD, Bekele EB, Furness AJ.

J Contam Hydrol. 2010 Sep 20;117(1-4):109-18. doi: 10.1016/j.jconhyd.2010.07.005. Epub 2010 Jul 24.

PMID:
20716466
19.

Fate of nine recycled water trace organic contaminants and metal(loid)s during managed aquifer recharge into a anaerobic aquifer: Column studies.

Patterson BM, Shackleton M, Furness AJ, Pearce J, Descourvieres C, Linge KL, Busetti F, Spadek T.

Water Res. 2010 Mar;44(5):1471-81. doi: 10.1016/j.watres.2009.10.044. Epub 2009 Nov 3.

PMID:
19939429

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