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Items: 1 to 50 of 81

1.

Essential role of the RNA-binding protein HuR in progenitor cell survival in mice.

Ghosh M, Aguila HL, Michaud J, Ai Y, Wu MT, Hemmes A, Ristimaki A, Guo C, Furneaux H, Hla T.

J Clin Invest. 2009 Dec;119(12):3530-43. doi: 10.1172/JCI38263. Epub 2009 Nov 2.

2.

The 5' terminal uracil of let-7a is critical for the recruitment of mRNA to Argonaute2.

Felice KM, Salzman DW, Shubert-Coleman J, Jensen KP, Furneaux HM.

Biochem J. 2009 Aug 13;422(2):329-41. doi: 10.1042/BJ20090534.

3.

Functional polymorphisms in the serotonin 1B receptor gene (HTR1B) predict self-reported anger and hostility among young men.

Conner TS, Jensen KP, Tennen H, Furneaux HM, Kranzler HR, Covault J.

Am J Med Genet B Neuropsychiatr Genet. 2010 Jan 5;153B(1):67-78. doi: 10.1002/ajmg.b.30955.

4.

A common polymorphism in serotonin receptor 1B mRNA moderates regulation by miR-96 and associates with aggressive human behaviors.

Jensen KP, Covault J, Conner TS, Tennen H, Kranzler HR, Furneaux HM.

Mol Psychiatry. 2009 Apr;14(4):381-9. doi: 10.1038/mp.2008.15. Epub 2008 Feb 19.

5.

MicroRNA regulation of cyclooxygenase-2 during embryo implantation.

Chakrabarty A, Tranguch S, Daikoku T, Jensen K, Furneaux H, Dey SK.

Proc Natl Acad Sci U S A. 2007 Sep 18;104(38):15144-9. Epub 2007 Sep 11.

6.

P68 RNA helicase unwinds the human let-7 microRNA precursor duplex and is required for let-7-directed silencing of gene expression.

Salzman DW, Shubert-Coleman J, Furneaux H.

J Biol Chem. 2007 Nov 9;282(45):32773-9. Epub 2007 Aug 27.

7.

Phosphorylation of HuR by Chk2 regulates SIRT1 expression.

Abdelmohsen K, Pullmann R Jr, Lal A, Kim HH, Galban S, Yang X, Blethrow JD, Walker M, Shubert J, Gillespie DA, Furneaux H, Gorospe M.

Mol Cell. 2007 Feb 23;25(4):543-57.

9.

Cytoplasmic HuR expression correlates with epithelial cancer cell but not with stromal cell cyclooxygenase-2 expression in mucinous ovarian carcinoma.

Erkinheimo TL, Sivula A, Lassus H, Heinonen M, Furneaux H, Haglund C, Butzow R, Ristimäki A.

Gynecol Oncol. 2005 Oct;99(1):14-9.

PMID:
16126263
10.

Cytoplasmic HuR expression is a prognostic factor in invasive ductal breast carcinoma.

Heinonen M, Bono P, Narko K, Chang SH, Lundin J, Joensuu H, Furneaux H, Hla T, Haglund C, Ristimäki A.

Cancer Res. 2005 Mar 15;65(6):2157-61.

11.
12.

GAP-43 mRNA in growth cones is associated with HuD and ribosomes.

Smith CL, Afroz R, Bassell GJ, Furneaux HM, Perrone-Bizzozero NI, Burry RW.

J Neurobiol. 2004 Nov;61(2):222-35.

13.

Cytoplasmic HuR expression correlates with poor outcome and with cyclooxygenase 2 expression in serous ovarian carcinoma.

Erkinheimo TL, Lassus H, Sivula A, Sengupta S, Furneaux H, Hla T, Haglund C, Butzow R, Ristimäki A.

Cancer Res. 2003 Nov 15;63(22):7591-4.

14.

Neuronal HuD gene encoding a mRNA stability regulator is transcriptionally repressed by thyroid hormone.

Cuadrado A, Navarro-Yubero C, Furneaux H, Muñoz A.

J Neurochem. 2003 Aug;86(3):763-73.

15.

Chronic lymphocytic leukemia with prostate infiltration mediated by specific clonal membrane-bound IgM.

Bogdan CA, Alexander AA, Gorny MK, Matute R, Marjanovic N, Zolla-Pazner S, Walden PD, Furneaux HM, Sidhu GS, Jacobson DR.

Cancer Res. 2003 May 1;63(9):2067-71.

16.

The RNA-binding protein HuR regulates the expression of cyclooxygenase-2.

Sengupta S, Jang BC, Wu MT, Paik JH, Furneaux H, Hla T.

J Biol Chem. 2003 Jul 4;278(27):25227-33. Epub 2003 Apr 18.

17.

Post-transcriptional regulation of soluble guanylyl cyclase expression in rat aorta.

Kloss S, Furneaux H, Mülsch A.

J Biol Chem. 2003 Jan 24;278(4):2377-83. Epub 2002 Nov 18.

18.

The 3'-untranslated region of p21WAF1 mRNA is a composite cis-acting sequence bound by RNA-binding proteins from breast cancer cells, including HuR and poly(C)-binding protein.

Giles KM, Daly JM, Beveridge DJ, Thomson AM, Voon DC, Furneaux HM, Jazayeri JA, Leedman PJ.

J Biol Chem. 2003 Jan 31;278(5):2937-46. Epub 2002 Nov 12.

19.

Novel binding of HuR and poly(C)-binding protein to a conserved UC-rich motif within the 3'-untranslated region of the androgen receptor messenger RNA.

Yeap BB, Voon DC, Vivian JP, McCulloch RK, Thomson AM, Giles KM, Czyzyk-Krzeska MF, Furneaux H, Wilce MC, Wilce JA, Leedman PJ.

J Biol Chem. 2002 Jul 26;277(30):27183-92. Epub 2002 May 13.

20.

HuD binds to three AU-rich sequences in the 3'-UTR of neuroserpin mRNA and promotes the accumulation of neuroserpin mRNA and protein.

Cuadrado A, Navarro-Yubero C, Furneaux H, Kinter J, Sonderegger P, Muñoz A.

Nucleic Acids Res. 2002 May 15;30(10):2202-11.

21.
22.

The RNA-binding protein HuD is required for GAP-43 mRNA stability, GAP-43 gene expression, and PKC-dependent neurite outgrowth in PC12 cells.

Mobarak CD, Anderson KD, Morin M, Beckel-Mitchener A, Rogers SL, Furneaux H, King P, Perrone-Bizzozero NI.

Mol Biol Cell. 2000 Sep;11(9):3191-203.

23.

Overexpression of HuD, but not of its truncated form HuD I+II, promotes GAP-43 gene expression and neurite outgrowth in PC12 cells in the absence of nerve growth factor.

Anderson KD, Morin MA, Beckel-Mitchener A, Mobarak CD, Neve RL, Furneaux HM, Burry R, Perrone-Bizzozero NI.

J Neurochem. 2000 Sep;75(3):1103-14.

24.

The identification of an endonuclease that cleaves within an HuR binding site in mRNA.

Zhao Z, Chang FC, Furneaux HM.

Nucleic Acids Res. 2000 Jul 15;28(14):2695-701.

25.

Complex contribution of the 3'-untranslated region to the expressional regulation of the human inducible nitric-oxide synthase gene. Involvement of the RNA-binding protein HuR.

Rodriguez-Pascual F, Hausding M, Ihrig-Biedert I, Furneaux H, Levy AP, Förstermann U, Kleinert H.

J Biol Chem. 2000 Aug 25;275(34):26040-9.

26.

HuR regulates cyclin A and cyclin B1 mRNA stability during cell proliferation.

Wang W, Caldwell MC, Lin S, Furneaux H, Gorospe M.

EMBO J. 2000 May 15;19(10):2340-50.

27.

Tumor antigen HuR binds specifically to one of five protein-binding segments in the 3'-untranslated region of the neurofibromin messenger RNA.

Haeussler J, Haeusler J, Striebel AM, Assum G, Vogel W, Furneaux H, Krone W.

Biochem Biophys Res Commun. 2000 Jan 27;267(3):726-32.

PMID:
10673359
28.

HuR regulates p21 mRNA stabilization by UV light.

Wang W, Furneaux H, Cheng H, Caldwell MC, Hutter D, Liu Y, Holbrook N, Gorospe M.

Mol Cell Biol. 2000 Feb;20(3):760-9.

29.

Embryonic lethal abnormal vision-like RNA-binding proteins regulate neurite outgrowth and tau expression in PC12 cells.

Aranda-Abreu GE, Behar L, Chung S, Furneaux H, Ginzburg I.

J Neurosci. 1999 Aug 15;19(16):6907-17.

30.

HuR, a novel target of anti-Hu antibodies, is expressed in non-neural tissues.

Nabors LB, Furneaux HM, King PH.

J Neuroimmunol. 1998 Dec 1;92(1-2):152-9.

PMID:
9916890
32.
33.

Complementary DNA libraries and neurological disease.

Joseph B, Furneaux H.

Arch Neurol. 1998 Jun;55(6):785-8. Review. No abstract available.

PMID:
9626768
34.

Hypoxic stabilization of vascular endothelial growth factor mRNA by the RNA-binding protein HuR.

Levy NS, Chung S, Furneaux H, Levy AP.

J Biol Chem. 1998 Mar 13;273(11):6417-23.

35.

The Elav-like proteins bind to AU-rich elements and to the poly(A) tail of mRNA.

Ma WJ, Chung S, Furneaux H.

Nucleic Acids Res. 1997 Sep 15;25(18):3564-9.

36.

The Elav-like proteins bind to a conserved regulatory element in the 3'-untranslated region of GAP-43 mRNA.

Chung S, Eckrich M, Perrone-Bizzozero N, Kohn DT, Furneaux H.

J Biol Chem. 1997 Mar 7;272(10):6593-8.

37.

Localization of the human HuR gene to chromosome 19p13.2.

Ma WJ, Furneaux H.

Hum Genet. 1997 Jan;99(1):32-3.

PMID:
9003489
38.

Purification and properties of HuD, a neuronal RNA-binding protein.

Chung S, Jiang L, Cheng S, Furneaux H.

J Biol Chem. 1996 May 10;271(19):11518-24.

39.

Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein.

Ma WJ, Cheng S, Campbell C, Wright A, Furneaux H.

J Biol Chem. 1996 Apr 5;271(14):8144-51.

40.
41.

Paraneoplastic encephalomyelitis antigens bind to the AU-rich elements of mRNA.

Liu J, Dalmau J, Szabo A, Rosenfeld M, Huber J, Furneaux H.

Neurology. 1995 Mar;45(3 Pt 1):544-50.

PMID:
7898713
42.

Hu neuronal proteins are expressed in proliferating neurogenic cells.

Marusich MF, Furneaux HM, Henion PD, Weston JA.

J Neurobiol. 1994 Feb;25(2):143-55.

PMID:
7517436
43.

Mapping of the gene coding for a paraneoplastic encephalomyelitis antigen (HuD) to human chromosome site 1p34.

Muresu R, Baldini A, Gress T, Posner JB, Furneaux HM, Siniscalco M.

Cytogenet Cell Genet. 1994;65(3):177-8.

PMID:
8222755
44.

Sera from some patients with antibody-associated paraneoplastic encephalomyelitis/sensory neuronopathy recognize the Ro-52K antigen.

Manley G, Wong E, Dalmau J, Elkon K, Posner J, Furneaux H.

J Neurooncol. 1994;19(2):105-12.

PMID:
7964985
45.

Sera from patients with Lambert-Eaton myasthenic syndrome recognize the beta-subunit of Ca2+ channel complexes.

Rosenfeld MR, Wong E, Dalmau J, Manley G, Egan D, Posner JB, Sher E, Furneaux HM.

Ann N Y Acad Sci. 1993 Jun 21;681:408-11. No abstract available.

PMID:
8395157
46.

Cloning and characterization of a Lambert-Eaton myasthenic syndrome antigen.

Rosenfeld MR, Wong E, Dalmau J, Manley G, Posner JB, Sher E, Furneaux HM.

Ann Neurol. 1993 Jan;33(1):113-20.

PMID:
8494331
47.
48.

p53 gene mutations in primary lung tumors are conserved in brain metastases.

Schlegel U, Rosenfeld MR, Volkenandt M, Rosenblum M, Dalmau J, Furneaux H.

J Neurooncol. 1992 Oct;14(2):93-100.

PMID:
1331352
49.

Epstein-Barr virus in acquired immune deficiency syndrome (AIDS) and non-AIDS primary central nervous system lymphoma.

DeAngelis LM, Wong E, Rosenblum M, Furneaux H.

Cancer. 1992 Sep 15;70(6):1607-11.

PMID:
1325277
50.

In situ mapping of the gene coding for a leucine zipper DNA binding protein (CDR62) to 16p12-16p13.1.

Gress T, Baldini A, Rocchi M, Furneaux H, Posner JB, Siniscalco M.

Genomics. 1992 Aug;13(4):1340-2.

PMID:
1505970

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