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Items: 6


Structure-based lead optimization to improve antiviral potency and ADMET properties of phenyl-1H-pyrrole-carboxamide entry inhibitors targeted to HIV-1 gp120.

Curreli F, Belov DS, Kwon YD, Ramesh R, Furimsky AM, O'Loughlin K, Byrge PC, Iyer LV, Mirsalis JC, Kurkin AV, Altieri A, Debnath AK.

Eur J Med Chem. 2018 Jun 25;154:367-391. doi: 10.1016/j.ejmech.2018.04.062. Epub 2018 May 12.


In vitro metabolism and stability of the actinide chelating agent 3,4,3-LI(1,2-HOPO).

Choi TA, Furimsky AM, Swezey R, Bunin DI, Byrge P, Iyer LV, Chang PY, Abergel RJ.

J Pharm Sci. 2015 May;104(5):1832-8. doi: 10.1002/jps.24394. Epub 2015 Feb 27.


The stereoselective sulfate conjugation of 4'-methoxyfenoterol stereoisomers by sulfotransferase enzymes.

Iyer LV, Ramamoorthy A, Rutkowska E, Furimsky AM, Tang L, Catz P, Green CE, Jozwiak K, Wainer IW.

Chirality. 2012 Oct;24(10):796-803. doi: 10.1002/chir.22072. Epub 2012 Jun 29.


Pharmacokinetics and metabolism of (R,R)-methoxyfenoterol in rat.

Siluk D, Mager DE, Kim HS, Wang Y, Furimsky AM, Ta A, Iyer LV, Green CE, Wainer IW.

Xenobiotica. 2010 Mar;40(3):195-206. doi: 10.3109/00498250903434533.


Effect of resveratrol on 17beta-estradiol sulfation by human hepatic and jejunal S9 and recombinant sulfotransferase 1E1.

Furimsky AM, Green CE, Sharp LE, Catz P, Adjei AA, Parman T, Kapetanovic IM, Weinshilboum RM, Iyer LV.

Drug Metab Dispos. 2008 Jan;36(1):129-36. Epub 2007 Oct 22.


Glucuronidation of trans-resveratrol by human liver and intestinal microsomes and UGT isoforms.

Brill SS, Furimsky AM, Ho MN, Furniss MJ, Li Y, Green AG, Bradford WW, Green CE, Kapetanovic IM, Iyer LV.

J Pharm Pharmacol. 2006 Apr;58(4):469-79.


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