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Items: 6

1.

Targeting the MAPK Signaling Pathway in Cancer: Promising Preclinical Activity with the Novel Selective ERK1/2 Inhibitor BVD-523 (Ulixertinib).

Germann UA, Furey BF, Markland W, Hoover RR, Aronov AM, Roix JJ, Hale M, Boucher DM, Sorrell DA, Martinez-Botella G, Fitzgibbon M, Shapiro P, Wick MJ, Samadani R, Meshaw K, Groover A, DeCrescenzo G, Namchuk M, Emery CM, Saha S, Welsch DJ.

Mol Cancer Ther. 2017 Nov;16(11):2351-2363. doi: 10.1158/1535-7163.MCT-17-0456. Epub 2017 Sep 22.

2.

Evaluating the immortal strand hypothesis in cancer stem cells: symmetric/self-renewal as the relevant surrogate marker of tumorigenicity.

Winquist RJ, Hall AB, Eustace BK, Furey BF.

Biochem Pharmacol. 2014 Sep 15;91(2):129-34. doi: 10.1016/j.bcp.2014.06.007. Epub 2014 Jun 24. Review.

PMID:
24971715
3.

Cancer stem cells as the relevant biomass for drug discovery.

Winquist RJ, Furey BF, Boucher DM.

Curr Opin Pharmacol. 2010 Aug;10(4):385-90. doi: 10.1016/j.coph.2010.06.008. Epub 2010 Jul 12. Review.

PMID:
20630801
4.

Janus kinase 2 inhibitors. Synthesis and characterization of a novel polycyclic azaindole.

Wang T, Duffy JP, Wang J, Halas S, Salituro FG, Pierce AC, Zuccola HJ, Black JR, Hogan JK, Jepson S, Shlyakter D, Mahajan S, Gu Y, Hoock T, Wood M, Furey BF, Frantz JD, Dauffenbach LM, Germann UA, Fan B, Namchuk M, Bennani YL, Ledeboer MW.

J Med Chem. 2009 Dec 24;52(24):7938-41. doi: 10.1021/jm901383u.

PMID:
20014869
5.

Targeting cancer stem cells for more effective therapies: Taking out cancer's locomotive engine.

Winquist RJ, Boucher DM, Wood M, Furey BF.

Biochem Pharmacol. 2009 Aug 15;78(4):326-34. doi: 10.1016/j.bcp.2009.03.020. Epub 2009 Apr 1.

PMID:
19539800
6.

Neonatal sex hormones have 'organizational' effects on the hypothalamic-pituitary-adrenal axis of male rats.

McCormick CM, Furey BF, Child M, Sawyer MJ, Donohue SM.

Brain Res Dev Brain Res. 1998 Feb 10;105(2):295-307.

PMID:
9541747

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