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Items: 1 to 50 of 63

1.

Endometrium and endometriosis tissue mitochondrial energy metabolism in a nonhuman primate model.

Atkins HM, Bharadwaj MS, O'Brien Cox A, Furdui CM, Appt SE, Caudell DL.

Reprod Biol Endocrinol. 2019 Aug 24;17(1):70. doi: 10.1186/s12958-019-0513-8.

2.

Mass Spectrometry in Advancement of Redox Precision Medicine.

Chen X, Lee J, Wu H, Tsang AW, Furdui CM.

Adv Exp Med Biol. 2019;1140:327-358. doi: 10.1007/978-3-030-15950-4_19. Review.

PMID:
31347057
3.

Impaired Regeneration Potential in Urinary Stem Cells Diagnosed from the Patients with Diabetic Nephropathy.

Xiong G, Tang W, Zhang D, He D, Wei G, Atala A, Liang XJ, Bleyer AJ, Bleyer ME, Yu J, Aloi JA, Ma JX, Furdui CM, Zhang Y.

Theranostics. 2019 May 31;9(14):4221-4232. doi: 10.7150/thno.34050. eCollection 2019.

4.

Steroyl-CoA Desaturase 1 (SCD1) protects ovarian cancer cells from ferroptotic cell death.

Tesfay L, Paul BT, Konstorum A, Deng Z, Cox AO, Lee J, Furdui CM, Hegde P, Torti FM, Torti SV.

Cancer Res. 2019 Jul 3. pii: canres.0369.2019. doi: 10.1158/0008-5472.CAN-19-0369. [Epub ahead of print]

PMID:
31270077
5.

Initial biological evaluations of 18F-KS1, a novel ascorbate derivative to image oxidative stress in cancer.

Solingapuram Sai KK, Bashetti N, Chen X, Norman S, Hines JW, Meka O, Kumar JVS, Devanathan S, Deep G, Furdui CM, Mintz A.

EJNMMI Res. 2019 May 17;9(1):43. doi: 10.1186/s13550-019-0513-x.

6.

Knee and Hip Joint Cartilage Damage from Combined Spaceflight Hazards of Low-Dose Radiation Less than 1 Gy and Prolonged Hindlimb Unloading.

Kwok AT, Moore JE, Rosas S, Kerr BA, Andrews RN, Nguyen CM, Lee J, Furdui CM, Collins BE, Munley MT, Willey JS.

Radiat Res. 2019 Jun;191(6):497-506. doi: 10.1667/RR15216.1. Epub 2019 Mar 29.

PMID:
30925135
7.

Triphenylphosphonium-Derived Protein Sulfenic Acid Trapping Agents: Synthesis, Reactivity, and Effect on Mitochondrial Function.

Li Z, Forshaw TE, Holmila RJ, Vance SA, Wu H, Poole LB, Furdui CM, King SB.

Chem Res Toxicol. 2019 Mar 18;32(3):526-534. doi: 10.1021/acs.chemrestox.8b00385. Epub 2019 Mar 4.

8.

Differential peroxiredoxin hyperoxidation regulates MAP kinase signaling in human articular chondrocytes.

Collins JA, Wood ST, Bolduc JA, Nurmalasari NPD, Chubinskaya S, Poole LB, Furdui CM, Nelson KJ, Loeser RF.

Free Radic Biol Med. 2019 Apr;134:139-152. doi: 10.1016/j.freeradbiomed.2019.01.005. Epub 2019 Jan 9.

PMID:
30639614
9.

Peroxiredoxins in Cancer and Response to Radiation Therapies.

Forshaw TE, Holmila R, Nelson KJ, Lewis JE, Kemp ML, Tsang AW, Poole LB, Lowther WT, Furdui CM.

Antioxidants (Basel). 2019 Jan 1;8(1). pii: E11. doi: 10.3390/antiox8010011. Review.

10.

Targeting NAD+ Metabolism to Enhance Radiation Therapy Responses.

Lewis JE, Singh N, Holmila RJ, Sumer BD, Williams NS, Furdui CM, Kemp ML, Boothman DA.

Semin Radiat Oncol. 2019 Jan;29(1):6-15. doi: 10.1016/j.semradonc.2018.10.009. Review.

PMID:
30573185
11.

Sulforaphane promotes chlamydial infection by suppressing mitochondrial protein oxidation and activation of complement C3.

Saez D, Dushime R, Wu H, Ramos Cordova LB, Shukla K, Brown-Harding H, Furdui CM, Tsang AW.

Protein Sci. 2019 Jan;28(1):216-227. doi: 10.1002/pro.3536.

PMID:
30367535
12.

Decreased expression of pigment epithelium-derived factor within the penile tissues contributes to erectile dysfunction in diabetic rats.

Qiao H, Zhang Y, Lin W, Wang YF, Furdui CM, Jiang Q, Li X, Long T, Wang Y, Qin DN.

Clin Sci (Lond). 2018 Oct 18;132(20):2175-2188. doi: 10.1042/CS20180192. Print 2018 Oct 31.

PMID:
30232174
13.

Cysteine thiol oxidation on SIRT2 regulates inflammation in obese mice with sepsis.

Wang X, Buechler NL, Long DL, Furdui CM, Yoza BK, McCall CE, Vachharajani V.

Inflammation. 2019 Feb;42(1):156-169. doi: 10.1007/s10753-018-0881-9.

PMID:
30203196
14.

H2O2 oxidation of cysteine residues in c-Jun N-terminal kinase 2 (JNK2) contributes to redox regulation in human articular chondrocytes.

Nelson KJ, Bolduc JA, Wu H, Collins JA, Burke EA, Reisz JA, Klomsiri C, Wood ST, Yammani RR, Poole LB, Furdui CM, Loeser RF.

J Biol Chem. 2018 Oct 19;293(42):16376-16389. doi: 10.1074/jbc.RA118.004613. Epub 2018 Sep 6.

PMID:
30190325
15.

Antioxidant treatment after injury suppresses second hit immune priming.

Hoth JJ, Smith LM, Furdui CM, Wells JD, Yoza BK, McCall CE.

J Trauma Acute Care Surg. 2018 Aug;85(2):367-374. doi: 10.1097/TA.0000000000001951.

PMID:
30080782
16.

Platination of cysteine by an epidermal growth factor receptor kinase-targeted hybrid agent.

Yang M, Wu H, Chu J, Gabriel LA, Kim Y, Anderson KS, Furdui CM, Bierbach U.

Chem Commun (Camb). 2018 Jul 11;54(54):7479-7482. doi: 10.1039/c8cc04251a. Epub 2018 Jun 19.

PMID:
29915817
17.

Novel hyperoxidation resistance motifs in 2-Cys peroxiredoxins.

Bolduc JA, Nelson KJ, Haynes AC, Lee J, Reisz JA, Graff AH, Clodfelter JE, Parsonage D, Poole LB, Furdui CM, Lowther WT.

J Biol Chem. 2018 Jul 27;293(30):11901-11912. doi: 10.1074/jbc.RA117.001690. Epub 2018 Jun 8.

18.

Mitochondria-targeted Probes for Imaging Protein Sulfenylation.

Holmila RJ, Vance SA, Chen X, Wu H, Shukla K, Bharadwaj MS, Mims J, Wary Z, Marrs G, Singh R, Molina AJ, Poole LB, King SB, Furdui CM.

Sci Rep. 2018 Apr 27;8(1):6635. doi: 10.1038/s41598-018-24493-x.

19.

Modulators of Redox Metabolism in Head and Neck Cancer.

Chen X, Mims J, Huang X, Singh N, Motea E, Planchon SM, Beg M, Tsang AW, Porosnicu M, Kemp ML, Boothman DA, Furdui CM.

Antioxid Redox Signal. 2018 Dec 1;29(16):1660-1690. doi: 10.1089/ars.2017.7423. Epub 2017 Dec 20. Review.

PMID:
29113454
20.

The Oxidative State of Cysteine Thiol 144 Regulates the SIRT6 Glucose Homeostat.

Long D, Wu H, Tsang AW, Poole LB, Yoza BK, Wang X, Vachharajani V, Furdui CM, McCall CE.

Sci Rep. 2017 Sep 8;7(1):11005. doi: 10.1038/s41598-017-11388-6.

21.

Endogenous, regulatory cysteine sulfenylation of ERK kinases in response to proliferative signals.

Keyes JD, Parsonage D, Yammani RD, Rogers LC, Kesty C, Furdui CM, Nelson KJ, Poole LB.

Free Radic Biol Med. 2017 Nov;112:534-543. doi: 10.1016/j.freeradbiomed.2017.08.018. Epub 2017 Aug 24.

22.

Genome-Scale Modeling of NADPH-Driven β-Lapachone Sensitization in Head and Neck Squamous Cell Carcinoma.

Lewis JE, Costantini F, Mims J, Chen X, Furdui CM, Boothman DA, Kemp ML.

Antioxid Redox Signal. 2018 Oct 1;29(10):937-952. doi: 10.1089/ars.2017.7048. Epub 2017 Sep 14.

23.

Discovery of Heteroaromatic Sulfones As a New Class of Biologically Compatible Thiol-Selective Reagents.

Chen X, Wu H, Park CM, Poole TH, Keceli G, Devarie-Baez NO, Tsang AW, Lowther WT, Poole LB, King SB, Xian M, Furdui CM.

ACS Chem Biol. 2017 Aug 18;12(8):2201-2208. doi: 10.1021/acschembio.7b00444. Epub 2017 Jul 19.

24.

Human Serum Albumin-Delivered [Au(PEt3)]+ Is a Potent Inhibitor of T Cell Proliferation.

Dean TC, Yang M, Liu M, Grayson JM, DeMartino AW, Day CS, Lee J, Furdui CM, Bierbach U.

ACS Med Chem Lett. 2017 Apr 25;8(5):572-576. doi: 10.1021/acsmedchemlett.7b00142. eCollection 2017 May 11.

25.

The SAMHD1 dNTP Triphosphohydrolase Is Controlled by a Redox Switch.

Mauney CH, Rogers LC, Harris RS, Daniel LW, Devarie-Baez NO, Wu H, Furdui CM, Poole LB, Perrino FW, Hollis T.

Antioxid Redox Signal. 2017 Dec 1;27(16):1317-1331. doi: 10.1089/ars.2016.6888. Epub 2017 Apr 18.

26.

The role of red blood cell S-nitrosation in nitrite bioactivation and its modulation by leucine and glucose.

Wajih N, Liu X, Shetty P, Basu S, Wu H, Hogg N, Patel RP, Furdui CM, Kim-Shapiro DB.

Redox Biol. 2016 Aug;8:415-21. doi: 10.1016/j.redox.2016.04.004. Epub 2016 Apr 30.

27.

Oxidative Stress Promotes Peroxiredoxin Hyperoxidation and Attenuates Pro-survival Signaling in Aging Chondrocytes.

Collins JA, Wood ST, Nelson KJ, Rowe MA, Carlson CS, Chubinskaya S, Poole LB, Furdui CM, Loeser RF.

J Biol Chem. 2016 Mar 25;291(13):6641-54. doi: 10.1074/jbc.M115.693523. Epub 2016 Jan 21.

28.

Crystal Structure and Substrate Specificity of Human Thioesterase 2: INSIGHTS INTO THE MOLECULAR BASIS FOR THE MODULATION OF FATTY ACID SYNTHASE.

Ritchie MK, Johnson LC, Clodfelter JE, Pemble CW 4th, Fulp BE, Furdui CM, Kridel SJ, Lowther WT.

J Biol Chem. 2016 Feb 12;291(7):3520-30. doi: 10.1074/jbc.M115.702597. Epub 2015 Dec 9.

29.

The Human Pancreas as a Source of Protolerogenic Extracellular Matrix Scaffold for a New-generation Bioartificial Endocrine Pancreas.

Peloso A, Urbani L, Cravedi P, Katari R, Maghsoudlou P, Fallas ME, Sordi V, Citro A, Purroy C, Niu G, McQuilling JP, Sittadjody S, Farney AC, Iskandar SS, Zambon JP, Rogers J, Stratta RJ, Opara EC, Piemonti L, Furdui CM, Soker S, De Coppi P, Orlando G.

Ann Surg. 2016 Jul;264(1):169-79. doi: 10.1097/SLA.0000000000001364.

30.

Characterization of circulating APOL1 protein complexes in African Americans.

Weckerle A, Snipes JA, Cheng D, Gebre AK, Reisz JA, Murea M, Shelness GS, Hawkins GA, Furdui CM, Freedman BI, Parks JS, Ma L.

J Lipid Res. 2016 Jan;57(1):120-30. doi: 10.1194/jlr.M063453. Epub 2015 Nov 18.

31.

Biological chemistry and functionality of protein sulfenic acids and related thiol modifications.

Devarie-Baez NO, Silva Lopez EI, Furdui CM.

Free Radic Res. 2016;50(2):172-94. doi: 10.3109/10715762.2015.1090571. Epub 2015 Nov 11. Review.

32.

Cysteine-Mediated Redox Regulation of Cell Signaling in Chondrocytes Stimulated With Fibronectin Fragments.

Wood ST, Long DL, Reisz JA, Yammani RR, Burke EA, Klomsiri C, Poole LB, Furdui CM, Loeser RF.

Arthritis Rheumatol. 2016 Jan;68(1):117-26. doi: 10.1002/art.39326.

33.

Differential cytotoxic and radiosensitizing effects of silver nanoparticles on triple-negative breast cancer and non-triple-negative breast cells.

Swanner J, Mims J, Carroll DL, Akman SA, Furdui CM, Torti SV, Singh RN.

Int J Nanomedicine. 2015 Jun 11;10:3937-53. doi: 10.2147/IJN.S80349. eCollection 2015.

34.

Analysis of DNA methylation and gene expression in radiation-resistant head and neck tumors.

Chen X, Liu L, Mims J, Punska EC, Williams KE, Zhao W, Arcaro KF, Tsang AW, Zhou X, Furdui CM.

Epigenetics. 2015;10(6):545-61. doi: 10.1080/15592294.2015.1048953.

35.

Energy metabolism in a matched model of radiation resistance for head and neck squamous cell cancer.

Mims J, Bansal N, Bharadwaj MS, Chen X, Molina AJ, Tsang AW, Furdui CM.

Radiat Res. 2015 Mar;183(3):291-304. doi: 10.1667/RR13828.1. Epub 2015 Mar 4.

36.

Dissecting peroxiredoxin catalysis: separating binding, peroxidation, and resolution for a bacterial AhpC.

Parsonage D, Nelson KJ, Ferrer-Sueta G, Alley S, Karplus PA, Furdui CM, Poole LB.

Biochemistry. 2015 Feb 24;54(7):1567-75. doi: 10.1021/bi501515w. Epub 2015 Feb 10.

37.

Activation of epidermal growth factor receptor is required for Chlamydia trachomatis development.

Patel AL, Chen X, Wood ST, Stuart ES, Arcaro KF, Molina DP, Petrovic S, Furdui CM, Tsang AW.

BMC Microbiol. 2014 Dec 4;14:277. doi: 10.1186/s12866-014-0277-4.

38.

Mass spectrometry in studies of protein thiol chemistry and signaling: opportunities and caveats.

Baez NO, Reisz JA, Furdui CM.

Free Radic Biol Med. 2015 Mar;80:191-211. doi: 10.1016/j.freeradbiomed.2014.09.016. Epub 2014 Sep 28. Review.

39.

Strained cycloalkynes as new protein sulfenic acid traps.

Poole TH, Reisz JA, Zhao W, Poole LB, Furdui CM, King SB.

J Am Chem Soc. 2014 Apr 30;136(17):6167-70. doi: 10.1021/ja500364r. Epub 2014 Apr 16.

40.

Ionizing radiation: mechanisms and therapeutics.

Furdui CM.

Antioxid Redox Signal. 2014 Jul 10;21(2):218-20. doi: 10.1089/ars.2014.5935. Epub 2014 May 16.

41.

Broad phenotypic changes associated with gain of radiation resistance in head and neck squamous cell cancer.

Bansal N, Mims J, Kuremsky JG, Olex AL, Zhao W, Yin L, Wani R, Qian J, Center B, Marrs GS, Porosnicu M, Fetrow JS, Tsang AW, Furdui CM.

Antioxid Redox Signal. 2014 Jul 10;21(2):221-36. doi: 10.1089/ars.2013.5690. Epub 2014 Apr 10.

42.

Effects of ionizing radiation on biological molecules--mechanisms of damage and emerging methods of detection.

Reisz JA, Bansal N, Qian J, Zhao W, Furdui CM.

Antioxid Redox Signal. 2014 Jul 10;21(2):260-92. doi: 10.1089/ars.2013.5489. Epub 2014 Feb 21. Review.

43.

Chemical approaches to detect and analyze protein sulfenic acids.

Furdui CM, Poole LB.

Mass Spectrom Rev. 2014 Mar-Apr;33(2):126-46. doi: 10.1002/mas.21384. Epub 2013 Sep 17. Review.

44.

Thiol-blocking electrophiles interfere with labeling and detection of protein sulfenic acids.

Reisz JA, Bechtold E, King SB, Poole LB, Furdui CM.

FEBS J. 2013 Dec;280(23):6150-61. doi: 10.1111/febs.12535. Epub 2013 Oct 16.

45.

Molecular basis for the resistance of human mitochondrial 2-Cys peroxiredoxin 3 to hyperoxidation.

Haynes AC, Qian J, Reisz JA, Furdui CM, Lowther WT.

J Biol Chem. 2013 Oct 11;288(41):29714-23. doi: 10.1074/jbc.M113.473470. Epub 2013 Sep 3.

46.

Vascular bioactivation of nitroglycerin by aldehyde dehydrogenase-2: reaction intermediates revealed by crystallography and mass spectrometry.

Lang BS, Gorren AC, Oberdorfer G, Wenzl MV, Furdui CM, Poole LB, Mayer B, Gruber K.

J Biol Chem. 2012 Nov 2;287(45):38124-34. doi: 10.1074/jbc.M112.371716. Epub 2012 Sep 17.

47.

Myosin heavy chain isoform expression in the Vastus Lateralis muscle of aging African green vervet monkeys.

Feng X, Zhang T, Xu Z, Choi SJ, Qian J, Furdui CM, Register TC, Delbono O.

Exp Gerontol. 2012 Aug;47(8):601-7. doi: 10.1016/j.exger.2012.05.007. Epub 2012 May 14.

48.

A simple and effective strategy for labeling cysteine sulfenic acid in proteins by utilization of β-ketoesters as cleavable probes.

Qian J, Wani R, Klomsiri C, Poole LB, Tsang AW, Furdui CM.

Chem Commun (Camb). 2012 Apr 28;48(34):4091-3. doi: 10.1039/c2cc17868k. Epub 2012 Mar 20.

49.

Oxidation of Akt2 kinase promotes cell migration and regulates G1-S transition in the cell cycle.

Wani R, Bharathi NS, Field J, Tsang AW, Furdui CM.

Cell Cycle. 2011 Oct 1;10(19):3263-8. doi: 10.4161/cc.10.19.17738. Epub 2011 Oct 1.

50.

Simple synthesis of 1,3-cyclopentanedione derived probes for labeling sulfenic acid proteins.

Qian J, Klomsiri C, Wright MW, King SB, Tsang AW, Poole LB, Furdui CM.

Chem Commun (Camb). 2011 Aug 28;47(32):9203-5. doi: 10.1039/c1cc12127h. Epub 2011 Jul 8.

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