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Items: 1 to 50 of 53

1.

Phosphatase of regenerating liver sensitizes MET to functional activation by hepatocyte growth factor.

Kojima T, Funato Y, Miki H.

Biochem J. 2019 May 21;476(10):1419-1431. doi: 10.1042/BCJ20190071.

PMID:
31036720
2.

Cnnm4 deficiency suppresses Ca2+ signaling and promotes cell proliferation in the colon epithelia.

Yamazaki D, Hasegawa A, Funato Y, Tran HN, Mori MX, Mori Y, Sato T, Miki H.

Oncogene. 2019 May;38(20):3962-3969. doi: 10.1038/s41388-019-0682-0. Epub 2019 Jan 22.

PMID:
30670776
3.

Molecular function and biological importance of CNNM family Mg2+ transporters.

Funato Y, Miki H.

J Biochem. 2019 Mar 1;165(3):219-225. doi: 10.1093/jb/mvy095. Review.

PMID:
30476181
4.

The cyclic nucleotide-binding homology domain of the integral membrane protein CNNM mediates dimerization and is required for Mg2+ efflux activity.

Chen YS, Kozlov G, Fakih R, Funato Y, Miki H, Gehring K.

J Biol Chem. 2018 Dec 28;293(52):19998-20007. doi: 10.1074/jbc.RA118.005672. Epub 2018 Oct 19.

5.

[Predictive Factors for Gastrointestinal Bleeding Following Hemorrhagic Stroke: A Hospital-Based Cohort Study].

Inoue H, Miyahara M, Funato Y, Ozaki S, Kato K, Noda R, Yamaguchi S, Tamai Y, Inoue M, Okamoto K, Hara T.

Brain Nerve. 2018 Aug;70(8):943-946. doi: 10.11477/mf.1416201105. Japanese.

PMID:
30082503
6.

Evaluation of Usefulness of Propiverine Hydrochloride in Poor Responders to Previous Anticholinergics.

Masumori N, Funato Y, Yamaguchi Y, Itoh K.

Low Urin Tract Symptoms. 2018 May;10(2):116-121. doi: 10.1111/luts.12145. Epub 2016 Nov 5.

PMID:
29664239
7.

Visualization of long-term Mg2+ dynamics in apoptotic cells using a novel targetable fluorescent probe.

Matsui Y, Funato Y, Imamura H, Miki H, Mizukami S, Kikuchi K.

Chem Sci. 2017 Dec 1;8(12):8255-8264. doi: 10.1039/c7sc03954a. Epub 2017 Oct 20.

8.

Phosphatase of regenerating liver maintains cellular magnesium homeostasis.

Yoshida A, Funato Y, Miki H.

Biochem J. 2018 Mar 26;475(6):1129-1139. doi: 10.1042/BCJ20170756.

PMID:
29487165
9.

Rebuttal from Yosuke Funato, Kazuharu Furutani, Yoshihisa Kurachi and Hiroaki Miki.

Funato Y, Furutani K, Kurachi Y, Miki H.

J Physiol. 2018 Mar 1;596(5):751. doi: 10.1113/JP275706. Epub 2018 Jan 31. No abstract available.

10.

CrossTalk proposal: CNNM proteins are Na+ /Mg2+ exchangers playing a central role in transepithelial Mg2+ (re)absorption.

Funato Y, Furutani K, Kurachi Y, Miki H.

J Physiol. 2018 Mar 1;596(5):743-746. doi: 10.1113/JP275248. Epub 2018 Jan 31. No abstract available.

11.

Renal function of cyclin M2 Mg2+ transporter maintains blood pressure.

Funato Y, Yamazaki D, Miki H.

J Hypertens. 2017 Mar;35(3):585-592. doi: 10.1097/HJH.0000000000001211.

PMID:
28033128
12.

Phosphocysteine in the PRL-CNNM pathway mediates magnesium homeostasis.

Gulerez I, Funato Y, Wu H, Yang M, Kozlov G, Miki H, Gehring K.

EMBO Rep. 2016 Dec;17(12):1890-1900. Epub 2016 Nov 17.

13.

Mg2+ Extrusion from Intestinal Epithelia by CNNM Proteins Is Essential for Gonadogenesis via AMPK-TORC1 Signaling in Caenorhabditis elegans.

Ishii T, Funato Y, Hashizume O, Yamazaki D, Hirata Y, Nishiwaki K, Kono N, Arai H, Miki H.

PLoS Genet. 2016 Aug 26;12(8):e1006276. doi: 10.1371/journal.pgen.1006276. eCollection 2016 Aug.

14.

Complementary role of CNNM2 in sperm motility and Ca(2+) influx during capacitation.

Yamazaki D, Funato Y, Miyata H, Ikawa M, Miki H.

Biochem Biophys Res Commun. 2016 Jun 3;474(3):441-446. doi: 10.1016/j.bbrc.2016.05.001. Epub 2016 May 2.

PMID:
27150626
15.

The Mg2+ transporter CNNM4 regulates sperm Ca2+ homeostasis and is essential for reproduction.

Yamazaki D, Miyata H, Funato Y, Fujihara Y, Ikawa M, Miki H.

J Cell Sci. 2016 May 1;129(9):1940-9. doi: 10.1242/jcs.182220. Epub 2016 Mar 22.

16.

[Results of a Special Drug Use-Results Survey on Compliance to Tegafur/Uracil(UFT)Adjuvant Chemotherapy for Non-Small Cell Lung Cancer].

Koyama T, Funato Y, Yamaguchi Y, Oda M, Ito K.

Gan To Kagaku Ryoho. 2015 Aug;42(8):973-80. Japanese.

PMID:
26321712
17.

[Results of a drug use investigation of nanoparticle albumin-bound Paclitaxel for breast cancer].

Nakamura S, Iwata H, Funato Y, Ito K, Ito Y.

Gan To Kagaku Ryoho. 2015 Apr;42(4):447-55. Japanese.

PMID:
25963691
18.

A new technique for analyzing trace element uptake by human enamel.

Funato Y, Matsuda Y, Okuyama K, Yamamoto H, Komatsu H, Sano H.

Dent Mater J. 2015;34(2):240-5. doi: 10.4012/dmj.2014-127. Epub 2015 Feb 25.

19.

Basolateral sorting of the Mg²⁺ transporter CNNM4 requires interaction with AP-1A and AP-1B.

Hirata Y, Funato Y, Miki H.

Biochem Biophys Res Commun. 2014 Dec 12;455(3-4):184-9. doi: 10.1016/j.bbrc.2014.10.138. Epub 2014 Nov 10.

PMID:
25449265
20.

Membrane protein CNNM4-dependent Mg2+ efflux suppresses tumor progression.

Funato Y, Yamazaki D, Mizukami S, Du L, Kikuchi K, Miki H.

J Clin Invest. 2014 Dec;124(12):5398-410. doi: 10.1172/JCI76614. Epub 2014 Oct 27.

21.

Reconstruction of insulin signal flow from phosphoproteome and metabolome data.

Yugi K, Kubota H, Toyoshima Y, Noguchi R, Kawata K, Komori Y, Uda S, Kunida K, Tomizawa Y, Funato Y, Miki H, Matsumoto M, Nakayama KI, Kashikura K, Endo K, Ikeda K, Soga T, Kuroda S.

Cell Rep. 2014 Aug 21;8(4):1171-83. doi: 10.1016/j.celrep.2014.07.021. Epub 2014 Aug 14.

22.

Mg2+-dependent interactions of ATP with the cystathionine-β-synthase (CBS) domains of a magnesium transporter.

Hirata Y, Funato Y, Takano Y, Miki H.

J Biol Chem. 2014 May 23;289(21):14731-9. doi: 10.1074/jbc.M114.551176. Epub 2014 Apr 6.

23.

Basolateral Mg2+ extrusion via CNNM4 mediates transcellular Mg2+ transport across epithelia: a mouse model.

Yamazaki D, Funato Y, Miura J, Sato S, Toyosawa S, Furutani K, Kurachi Y, Omori Y, Furukawa T, Tsuda T, Kuwabata S, Mizukami S, Kikuchi K, Miki H.

PLoS Genet. 2013;9(12):e1003983. doi: 10.1371/journal.pgen.1003983. Epub 2013 Dec 5.

24.

Nucleoredoxin regulates glucose metabolism via phosphofructokinase 1.

Funato Y, Hayashi T, Irino Y, Takenawa T, Miki H.

Biochem Biophys Res Commun. 2013 Nov 1;440(4):737-42. doi: 10.1016/j.bbrc.2013.09.138. Epub 2013 Oct 8.

PMID:
24120946
25.

Reversible oxidation of PRL family protein-tyrosine phosphatases.

Funato Y, Miki H.

Methods. 2014 Jan 15;65(2):184-9. doi: 10.1016/j.ymeth.2013.06.032. Epub 2013 Jul 2.

PMID:
23831336
26.

[Redox-dependent regulation of intracellular signaling via nucleoredoxin].

Funato Y, Miki H.

Seikagaku. 2013 Mar;85(3):174-8. Review. Japanese. No abstract available.

PMID:
23631312
27.

Survey of second-trimester maternal serum screening in Japan.

Okuyama T, Yotsumoto J, Funato Y.

J Obstet Gynaecol Res. 2013 May;39(5):942-7. doi: 10.1111/jog.12015. Epub 2013 Mar 20.

PMID:
23509876
28.

Thioredoxin-related protein 32 (TRP32) specifically reduces oxidized phosphatase of regenerating liver (PRL).

Ishii T, Funato Y, Miki H.

J Biol Chem. 2013 Mar 8;288(10):7263-70. doi: 10.1074/jbc.M112.418004. Epub 2013 Jan 28.

29.

Regulation of intracellular signalling through cysteine oxidation by reactive oxygen species.

Miki H, Funato Y.

J Biochem. 2012 Mar;151(3):255-61. doi: 10.1093/jb/mvs006. Epub 2012 Jan 27. Review.

PMID:
22287686
30.

Thioredoxin mediates oxidation-dependent phosphorylation of CRMP2 and growth cone collapse.

Morinaka A, Yamada M, Itofusa R, Funato Y, Yoshimura Y, Nakamura F, Yoshimura T, Kaibuchi K, Goshima Y, Hoshino M, Kamiguchi H, Miki H.

Sci Signal. 2011 Apr 26;4(170):ra26. doi: 10.1126/scisignal.2001127.

31.

Oligomeric peroxiredoxin-I is an essential intermediate for p53 to activate MST1 kinase and apoptosis.

Morinaka A, Funato Y, Uesugi K, Miki H.

Oncogene. 2011 Oct 6;30(40):4208-18. doi: 10.1038/onc.2011.139. Epub 2011 Apr 25.

PMID:
21516123
32.

An interaction between human Sec63 and nucleoredoxin may provide the missing link between the SEC63 gene and polycystic liver disease.

Müller L, Funato Y, Miki H, Zimmermann R.

FEBS Lett. 2011 Feb 18;585(4):596-600. doi: 10.1016/j.febslet.2011.01.024. Epub 2011 Jan 18.

33.

Nucleoredoxin sustains Wnt/β-catenin signaling by retaining a pool of inactive dishevelled protein.

Funato Y, Terabayashi T, Sakamoto R, Okuzaki D, Ichise H, Nojima H, Yoshida N, Miki H.

Curr Biol. 2010 Nov 9;20(21):1945-52. doi: 10.1016/j.cub.2010.09.065. Epub 2010 Oct 21.

34.

Nucleoredoxin negatively regulates Toll-like receptor 4 signaling via recruitment of flightless-I to myeloid differentiation primary response gene (88).

Hayashi T, Funato Y, Terabayashi T, Morinaka A, Sakamoto R, Ichise H, Fukuda H, Yoshida N, Miki H.

J Biol Chem. 2010 Jun 11;285(24):18586-93. doi: 10.1074/jbc.M110.106468. Epub 2010 Apr 16.

35.

Redox regulation of Wnt signalling via nucleoredoxin.

Funato Y, Miki H.

Free Radic Res. 2010 Apr;44(4):379-88. doi: 10.3109/10715761003610745. Review.

PMID:
20187711
36.

Discovery of candidate disease genes in ENU-induced mouse mutants by large-scale sequencing, including a splice-site mutation in nucleoredoxin.

Boles MK, Wilkinson BM, Wilming LG, Liu B, Probst FJ, Harrow J, Grafham D, Hentges KE, Woodward LP, Maxwell A, Mitchell K, Risley MD, Johnson R, Hirschi K, Lupski JR, Funato Y, Miki H, Marin-Garcia P, Matthews L, Coffey AJ, Parker A, Hubbard TJ, Rogers J, Bradley A, Adams DJ, Justice MJ.

PLoS Genet. 2009 Dec;5(12):e1000759. doi: 10.1371/journal.pgen.1000759. Epub 2009 Dec 11.

37.

A coated vesicle-associated kinase of 104 kDa (CVAK104) induces lysosomal degradation of frizzled 5 (Fzd5).

Terabayashi T, Funato Y, Fukuda M, Miki H.

J Biol Chem. 2009 Sep 25;284(39):26716-24. doi: 10.1074/jbc.M109.039313. Epub 2009 Jul 30.

38.

Dishevelled-induced phosphorylation regulates membrane localization of Par1b.

Terabayashi T, Funato Y, Miki H.

Biochem Biophys Res Commun. 2008 Oct 31;375(4):660-5. doi: 10.1016/j.bbrc.2008.08.098. Epub 2008 Aug 28.

PMID:
18760999
39.

Nucleoredoxin regulates the Wnt/planar cell polarity pathway in Xenopus.

Funato Y, Michiue T, Terabayashi T, Yukita A, Danno H, Asashima M, Miki H.

Genes Cells. 2008 Sep;13(9):965-75. doi: 10.1111/j.1365-2443.2008.01220.x. Epub 2008 Aug 6.

40.

Polarity-regulating kinase partitioning-defective 1/microtubule affinity-regulating kinase 2 negatively regulates development of dendrites on hippocampal neurons.

Terabayashi T, Itoh TJ, Yamaguchi H, Yoshimura Y, Funato Y, Ohno S, Miki H.

J Neurosci. 2007 Nov 28;27(48):13098-107.

41.

[Regulation of Wnt signal pathway via nucleoredoxin].

Funato Y, Miki H.

Seikagaku. 2007 Aug;79(8):796-9. Review. Japanese. No abstract available.

PMID:
17877029
42.

Nucleoredoxin, a novel thioredoxin family member involved in cell growth and differentiation.

Funato Y, Miki H.

Antioxid Redox Signal. 2007 Aug;9(8):1035-57. Review.

PMID:
17567240
43.

The thioredoxin-related redox-regulating protein nucleoredoxin inhibits Wnt-beta-catenin signalling through dishevelled.

Funato Y, Michiue T, Asashima M, Miki H.

Nat Cell Biol. 2006 May;8(5):501-8. Epub 2006 Apr 2.

PMID:
16604061
44.

IRSp53/Eps8 complex is important for positive regulation of Rac and cancer cell motility/invasiveness.

Funato Y, Terabayashi T, Suenaga N, Seiki M, Takenawa T, Miki H.

Cancer Res. 2004 Aug 1;64(15):5237-44.

45.

The formation of Kuiper-belt binaries through exchange reactions.

Funato Y, Makino J, Hut P, Kokubo E, Kinoshita D.

Nature. 2004 Feb 5;427(6974):518-20.

PMID:
14765188
46.

[Leiomyoma, leiomyosarcoma].

Kishikawa H, Nakamae K, Funato Y, Tanaka H.

Ryoikibetsu Shokogun Shirizu. 1994;(4):162-4. Review. Japanese. No abstract available.

PMID:
8007118
47.

[Operative indications for tracheobronchomalacia].

Niwa H, Yamakawa Y, Kawai T, Satake A, Hayashi M, Funato Y, Hara F, Masaoka A.

Nihon Kyobu Shikkan Gakkai Zasshi. 1992 Jun;30(6):1036-41. Japanese.

PMID:
1507677
48.

Distribution of thymic tissue in the mediastinal adipose tissue.

Fukai I, Funato Y, Mizuno T, Hashimoto T, Masaoka A.

J Thorac Cardiovasc Surg. 1991 Jun;101(6):1099-102.

PMID:
1710006
49.

[Electrophysiologic effects of atropine (author's transl)].

Ito M, Shinoda S, Tanno M, Funato Y, Sakurai K.

Kokyu To Junkan. 1975 Feb;23(2):149-55. Japanese. No abstract available.

PMID:
1169809
50.

[Recording of His bundle electrogram via the arm vein: Report of a case (author's transl)].

Ito M, Tanno M, Funato Y, Sakurai K, Suzuki H.

Kokyu To Junkan. 1975 Jan;23(1):57-60. Japanese. No abstract available.

PMID:
1170612

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