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Items: 1 to 50 of 73

1.

Vesicular and non-vesicular lipid export from the ER to the secretory pathway.

Funato K, Riezman H, Muñiz M.

Biochim Biophys Acta Mol Cell Biol Lipids. 2019 May 2. pii: S1388-1981(19)30066-6. doi: 10.1016/j.bbalip.2019.04.013. [Epub ahead of print] Review.

PMID:
31054928
2.

Target identification reveals lanosterol synthase as a vulnerability in glioma.

Phillips RE, Yang Y, Smith RC, Thompson BM, Yamasaki T, Soto-Feliciano YM, Funato K, Liang Y, Garcia-Bermudez J, Wang X, Garcia BA, Yamasaki K, McDonald JG, Birsoy K, Tabar V, Allis CD.

Proc Natl Acad Sci U S A. 2019 Apr 16;116(16):7957-7962. doi: 10.1073/pnas.1820989116. Epub 2019 Mar 28.

PMID:
30923116
3.

Sphingolipid/Pkh1/2-TORC1/Sch9 Signaling Regulates Ribosome Biogenesis in Tunicamycin-Induced Stress Response in Yeast.

Yabuki Y, Ikeda A, Araki M, Kajiwara K, Mizuta K, Funato K.

Genetics. 2019 May;212(1):175-186. doi: 10.1534/genetics.118.301874. Epub 2019 Mar 1.

PMID:
30824472
4.

Pevonedistat, a Neuronal Precursor Cell-Expressed Developmentally Down-Regulated Protein 8-Activating Enzyme Inhibitor, Is a Potent Inhibitor of Hepatitis B Virus.

Sekiba K, Otsuka M, Ohno M, Yamagami M, Kishikawa T, Seimiya T, Suzuki T, Tanaka E, Ishibashi R, Funato K, Koike K.

Hepatology. 2019 May;69(5):1903-1915. doi: 10.1002/hep.30491. Epub 2019 Mar 13.

PMID:
30586159
5.

Establishment and characterization of immortalized erythroid progenitor cell lines derived from a common cell source.

Kurita R, Funato K, Abe T, Watanabe Y, Shiba M, Tadokoro K, Nakamura Y, Nagai T, Satake M.

Exp Hematol. 2019 Jan;69:11-16. doi: 10.1016/j.exphem.2018.10.005. Epub 2018 Oct 13.

PMID:
30326248
6.

SIRT2-mediated inactivation of p73 is required for glioblastoma tumorigenicity.

Funato K, Hayashi T, Echizen K, Negishi L, Shimizu N, Koyama-Nasu R, Nasu-Nishimura Y, Morishita Y, Tabar V, Todo T, Ino Y, Mukasa A, Saito N, Akiyama T.

EMBO Rep. 2018 Nov;19(11). pii: e45587. doi: 10.15252/embr.201745587. Epub 2018 Sep 13.

PMID:
30213795
7.

Lysophospholipids Facilitate COPII Vesicle Formation.

Melero A, Chiaruttini N, Karashima T, Riezman I, Funato K, Barlowe C, Riezman H, Roux A.

Curr Biol. 2018 Jun 18;28(12):1950-1958.e6. doi: 10.1016/j.cub.2018.04.076. Epub 2018 Jun 7.

8.

Protection mechanisms against aberrant metabolism of sphingolipids in budding yeast.

Tani M, Funato K.

Curr Genet. 2018 Oct;64(5):1021-1028. doi: 10.1007/s00294-018-0826-8. Epub 2018 Mar 19. Review.

PMID:
29556757
9.

Protective role of the HOG pathway against the growth defect caused by impaired biosynthesis of complex sphingolipids in yeast Saccharomyces cerevisiae.

Yamaguchi Y, Katsuki Y, Tanaka S, Kawaguchi R, Denda H, Ikeda T, Funato K, Tani M.

Mol Microbiol. 2018 Feb;107(3):363-386. doi: 10.1111/mmi.13886. Epub 2017 Dec 22.

PMID:
29215176
10.

Gamma-aminobutyric acid fermentation with date residue by a lactic acid bacterium, Lactobacillus brevis.

Hasegawa M, Yamane D, Funato K, Yoshida A, Sambongi Y.

J Biosci Bioeng. 2018 Mar;125(3):316-319. doi: 10.1016/j.jbiosc.2017.10.003. Epub 2017 Oct 28.

PMID:
29089240
11.

Systemic Treatment Patterns With Advanced or Recurrent Non-small Cell Lung Cancer in Japan: A Retrospective Hospital Administrative Database Study.

Wang F, Mishina S, Takai S, Le TK, Ochi K, Funato K, Matsuoka S, Ohe Y.

Clin Ther. 2017 Jun;39(6):1146-1160. doi: 10.1016/j.clinthera.2017.04.010. Epub 2017 May 18.

12.

Arp2/3 complex and Mps3 are required for regulation of ribosome biosynthesis in the secretory stress response.

Yabuki Y, Katayama M, Kodama Y, Sakamoto A, Yatsuhashi A, Funato K, Mizuta K.

Yeast. 2017 Apr;34(4):155-163. doi: 10.1002/yea.3221. Epub 2017 Jan 12.

13.

Anti-Epidermal Growth Factor Receptor Gene Therapy for Glioblastoma.

Hicks MJ, Chiuchiolo MJ, Ballon D, Dyke JP, Aronowitz E, Funato K, Tabar V, Havlicek D, Fan F, Sondhi D, Kaminsky SM, Crystal RG.

PLoS One. 2016 Oct 6;11(10):e0162978. doi: 10.1371/journal.pone.0162978. eCollection 2016.

14.

Masseter Muscle Activity in Track and Field Athletes: A Pilot Study.

Nukaga H, Takeda T, Nakajima K, Narimatsu K, Ozawa T, Ishigami K, Funato K.

Open Dent J. 2016 Aug 31;10:474-485. eCollection 2016.

15.

The RNA Binding Protein Mex-3B Is Required for IL-33 Induction in the Development of Allergic Airway Inflammation.

Yamazumi Y, Sasaki O, Imamura M, Oda T, Ohno Y, Shiozaki-Sato Y, Nagai S, Suyama S, Kamoshida Y, Funato K, Yasui T, Kikutani H, Yamamoto K, Dohi M, Koyasu S, Akiyama T.

Cell Rep. 2016 Aug 30;16(9):2456-71. doi: 10.1016/j.celrep.2016.07.062. Epub 2016 Aug 18.

16.

Neuronal deficiency of ARV1 causes an autosomal recessive epileptic encephalopathy.

Palmer EE, Jarrett KE, Sachdev RK, Al Zahrani F, Hashem MO, Ibrahim N, Sampaio H, Kandula T, Macintosh R, Gupta R, Conlon DM, Billheimer JT, Rader DJ, Funato K, Walkey CJ, Lee CS, Loo C, Brammah S, Elakis G, Zhu Y, Buckley M, Kirk EP, Bye A, Alkuraya FS, Roscioli T, Lagor WR.

Hum Mol Genet. 2016 Jul 15;25(14):3042-3054. Epub 2016 Jun 6.

17.

A lipid regulator working at the cleavage furrow.

Eto K, Denda H, Funato K.

Cell Cycle. 2016 May 18;15(10):1315-6. doi: 10.1080/15384101.2016.1160663. Epub 2016 Apr 22. No abstract available.

18.

Producing human ceramide-NS by metabolic engineering using yeast Saccharomyces cerevisiae.

Murakami S, Shimamoto T, Nagano H, Tsuruno M, Okuhara H, Hatanaka H, Tojo H, Kodama Y, Funato K.

Sci Rep. 2015 Nov 17;5:16319. doi: 10.1038/srep16319.

19.

Complementation analysis reveals a potential role of human ARV1 in GPI anchor biosynthesis.

Ikeda A, Kajiwara K, Iwamoto K, Makino A, Kobayashi T, Mizuta K, Funato K.

Yeast. 2016 Feb;33(2):37-42. doi: 10.1002/yea.3138. Epub 2015 Nov 2.

20.

The essential function of Rrs1 in ribosome biogenesis is conserved in budding and fission yeasts.

Wan K, Kawara H, Yamamoto T, Kume K, Yabuki Y, Goshima T, Kitamura K, Ueno M, Kanai M, Hirata D, Funato K, Mizuta K.

Yeast. 2015 Sep;32(9):607-14. doi: 10.1002/yea.3083. Epub 2015 Jul 20.

21.

Sphingolipids regulate telomere clustering by affecting the transcription of genes involved in telomere homeostasis.

Ikeda A, Muneoka T, Murakami S, Hirota A, Yabuki Y, Karashima T, Nakazono K, Tsuruno M, Pichler H, Shirahige K, Kodama Y, Shimamoto T, Mizuta K, Funato K.

J Cell Sci. 2015 Jul 15;128(14):2454-67. doi: 10.1242/jcs.164160. Epub 2015 Jun 4.

22.

SMY2 and SYH1 suppress defects in ribosome biogenesis caused by ebp2 mutations.

Okano A, Wan K, Kanda K, Yabuki Y, Funato K, Mizuta K.

Biosci Biotechnol Biochem. 2015;79(9):1481-3. doi: 10.1080/09168451.2015.1031077. Epub 2015 Apr 7.

PMID:
25849478
23.

COPII coat composition is actively regulated by luminal cargo maturation.

Manzano-Lopez J, Perez-Linero AM, Aguilera-Romero A, Martin ME, Okano T, Silva DV, Seeberger PH, Riezman H, Funato K, Goder V, Wellinger RE, Muñiz M.

Curr Biol. 2015 Jan 19;25(2):152-162. doi: 10.1016/j.cub.2014.11.039. Epub 2014 Dec 31.

24.

Use of human embryonic stem cells to model pediatric gliomas with H3.3K27M histone mutation.

Funato K, Major T, Lewis PW, Allis CD, Tabar V.

Science. 2014 Dec 19;346(6216):1529-33. doi: 10.1126/science.1253799. Epub 2014 Nov 20.

25.

Genetic modification of neurons to express bevacizumab for local anti-angiogenesis treatment of glioblastoma.

Hicks MJ, Funato K, Wang L, Aronowitz E, Dyke JP, Ballon DJ, Havlicek DF, Frenk EZ, De BP, Chiuchiolo MJ, Sondhi D, Hackett NR, Kaminsky SM, Tabar V, Crystal RG.

Cancer Gene Ther. 2015 Jan;22(1):1-8. doi: 10.1038/cgt.2014.58. Epub 2014 Dec 12.

26.

Osh proteins regulate COPII-mediated vesicular transport of ceramide from the endoplasmic reticulum in budding yeast.

Kajiwara K, Ikeda A, Aguilera-Romero A, Castillon GA, Kagiwada S, Hanada K, Riezman H, Muñiz M, Funato K.

J Cell Sci. 2014 Jan 15;127(Pt 2):376-87. doi: 10.1242/jcs.132001. Epub 2013 Nov 8.

27.

The pleiotrophin-ALK axis is required for tumorigenicity of glioblastoma stem cells.

Koyama-Nasu R, Haruta R, Nasu-Nishimura Y, Taniue K, Katou Y, Shirahige K, Todo T, Ino Y, Mukasa A, Saito N, Matsui M, Takahashi R, Hoshino-Okubo A, Sugano H, Manabe E, Funato K, Akiyama T.

Oncogene. 2014 Apr 24;33(17):2236-44. doi: 10.1038/onc.2013.168. Epub 2013 May 20.

PMID:
23686309
28.

Physiological and physical characteristics of elite dragon boat paddlers.

Ho SR, Smith RM, Chapman PG, Sinclair PJ, Funato K.

J Strength Cond Res. 2013 Jan;27(1):137-45. doi: 10.1519/JSC.0b013e318252f612.

PMID:
23254488
29.

Perturbation of sphingolipid metabolism induces endoplasmic reticulum stress-mediated mitochondrial apoptosis in budding yeast.

Kajiwara K, Muneoka T, Watanabe Y, Karashima T, Kitagaki H, Funato K.

Mol Microbiol. 2012 Dec;86(5):1246-61. doi: 10.1111/mmi.12056. Epub 2012 Oct 17.

30.

The critical role of cyclin D2 in cell cycle progression and tumorigenicity of glioblastoma stem cells.

Koyama-Nasu R, Nasu-Nishimura Y, Todo T, Ino Y, Saito N, Aburatani H, Funato K, Echizen K, Sugano H, Haruta R, Matsui M, Takahashi R, Manabe E, Oda T, Akiyama T.

Oncogene. 2013 Aug 15;32(33):3840-5. doi: 10.1038/onc.2012.399. Epub 2012 Sep 10.

PMID:
22964630
31.
32.

The yeast p24 complex regulates GPI-anchored protein transport and quality control by monitoring anchor remodeling.

Castillon GA, Aguilera-Romero A, Manzano-Lopez J, Epstein S, Kajiwara K, Funato K, Watanabe R, Riezman H, Muñiz M.

Mol Biol Cell. 2011 Aug 15;22(16):2924-36. doi: 10.1091/mbc.E11-04-0294. Epub 2011 Jun 16.

33.

Tyrosine phosphatase PTPRD suppresses colon cancer cell migration in coordination with CD44.

Funato K, Yamazumi Y, Oda T, Akiyama T.

Exp Ther Med. 2011 May;2(3):457-463. Epub 2011 Mar 21.

34.

Central nervous system T-cell lymphoma in acquired immunodeficiency syndrome.

Yotsumoto M, Funato K, Hashimoto Y, Fujimoto H, Fukutake K.

Br J Haematol. 2010 Mar;148(5):807-8. doi: 10.1111/j.1365-2141.2009.07990.x. Epub 2009 Nov 13. No abstract available.

PMID:
19912221
35.

Functional interactions between sphingolipids and sterols in biological membranes regulating cell physiology.

Guan XL, Souza CM, Pichler H, Dewhurst G, Schaad O, Kajiwara K, Wakabayashi H, Ivanova T, Castillon GA, Piccolis M, Abe F, Loewith R, Funato K, Wenk MR, Riezman H.

Mol Biol Cell. 2009 Apr;20(7):2083-95. doi: 10.1091/mbc.E08-11-1126. Epub 2009 Feb 18.

36.

Muscle force per cross-sectional area is inversely related with pennation angle in strength trained athletes.

Ikegawa S, Funato K, Tsunoda N, Kanehisa H, Fukunaga T, Kawakami Y.

J Strength Cond Res. 2008 Jan;22(1):128-31. doi: 10.1519/JSC.0b013e31815f2fd3.

PMID:
18296965
37.

Yeast ARV1 is required for efficient delivery of an early GPI intermediate to the first mannosyltransferase during GPI assembly and controls lipid flow from the endoplasmic reticulum.

Kajiwara K, Watanabe R, Pichler H, Ihara K, Murakami S, Riezman H, Funato K.

Mol Biol Cell. 2008 May;19(5):2069-82. doi: 10.1091/mbc.E07-08-0740. Epub 2008 Feb 20.

38.

The development of trunk muscles in male wrestlers assessed by magnetic resonance imaging.

Kubo J, Ohta A, Takahashi H, Kukidome T, Funato K.

J Strength Cond Res. 2007 Nov;21(4):1251-4.

PMID:
18076225
39.

The oncoprotein NPM-ALK of anaplastic large-cell lymphoma induces JUNB transcription via ERK1/2 and JunB translation via mTOR signaling.

Staber PB, Vesely P, Haq N, Ott RG, Funato K, Bambach I, Fuchs C, Schauer S, Linkesch W, Hrzenjak A, Dirks WG, Sexl V, Bergler H, Kadin ME, Sternberg DW, Kenner L, Hoefler G.

Blood. 2007 Nov 1;110(9):3374-83. Epub 2007 Aug 9.

40.

Ethanol-induced death in yeast exhibits features of apoptosis mediated by mitochondrial fission pathway.

Kitagaki H, Araki Y, Funato K, Shimoi H.

FEBS Lett. 2007 Jun 26;581(16):2935-42. Epub 2007 May 29.

41.

Physiological responses to interval training sessions at velocities associated with VO2max.

Rozenek R, Funato K, Kubo J, Hoshikawa M, Matsuo A.

J Strength Cond Res. 2007 Feb;21(1):188-92.

PMID:
17313282
42.

Sphingoid base is required for translation initiation during heat stress in Saccharomyces cerevisiae.

Meier KD, Deloche O, Kajiwara K, Funato K, Riezman H.

Mol Biol Cell. 2006 Mar;17(3):1164-75. Epub 2005 Dec 28.

43.

Profiles of muscularity in junior Olympic weight lifters.

Kanehisa H, Funato K, Abe T, Fukunaga T.

J Sports Med Phys Fitness. 2005 Mar;45(1):77-83.

PMID:
16208294
44.

Kinetic resolution of rac-phenylalanine by stereoselective complexation to a chiral cobalt complex through pi-pi stacking interaction.

Jitsukawa K, Katoh A, Funato K, Ohata N, Funahashi Y, Ozawa T, Masuda H.

Inorg Chem. 2003 Oct 6;42(20):6163-5.

PMID:
14514289
45.

Growth trend of the quadriceps femoris muscle in junior Olympic weight lifters: an 18-month follow-up survey.

Kanehisa H, Funato K, Kuno S, Fukunaga T, Katsuta S.

Eur J Appl Physiol. 2003 May;89(3-4):238-42. Epub 2003 Mar 25.

PMID:
12736831
46.

Lcb4p is a key regulator of ceramide synthesis from exogenous long chain sphingoid base in Saccharomyces cerevisiae.

Funato K, Lombardi R, Vallee B, Riezman H.

J Biol Chem. 2003 Feb 28;278(9):7325-34. Epub 2002 Dec 18.

47.

Biosynthesis and trafficking of sphingolipids in the yeast Saccharomyces cerevisiae.

Funato K, Vallée B, Riezman H.

Biochemistry. 2002 Dec 24;41(51):15105-14. Review. No abstract available.

PMID:
12484746
48.

Sphingolipids are required for the stable membrane association of glycosylphosphatidylinositol-anchored proteins in yeast.

Watanabe R, Funato K, Venkataraman K, Futerman AH, Riezman H.

J Biol Chem. 2002 Dec 20;277(51):49538-44. Epub 2002 Oct 18.

50.

[Sphingolipid biosynthesis and traffic in yeast].

Funato K.

Seikagaku. 2002 Apr;74(4):317-21. Review. Japanese. No abstract available.

PMID:
12030035

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