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Items: 41

1.

A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases.

Garzia L, Kijima N, Morrissy AS, De Antonellis P, Guerreiro-Stucklin A, Holgado BL, Wu X, Wang X, Parsons M, Zayne K, Manno A, Kuzan-Fischer C, Nor C, Donovan LK, Liu J, Qin L, Garancher A, Liu KW, Mansouri S, Luu B, Thompson YY, Ramaswamy V, Peacock J, Farooq H, Skowron P, Shih DJH, Li A, Ensan S, Robbins CS, Cybulsky M, Mitra S, Ma Y, Moore R, Mungall A, Cho YJ, Weiss WA, Chan JA, Hawkins CE, Massimino M, Jabado N, Zapotocky M, Sumerauer D, Bouffet E, Dirks P, Tabori U, Sorensen PHB, Brastianos PK, Aldape K, Jones SJM, Marra MA, Woodgett JR, Wechsler-Reya RJ, Fults DW, Taylor MD.

Cell. 2018 May 31;173(6):1549. doi: 10.1016/j.cell.2018.05.033. Epub 2018 May 31. No abstract available.

PMID:
29856958
2.

Neurosurgeons still wanted.

Fults DW.

Neuro Oncol. 2018 May 30. doi: 10.1093/neuonc/noy081. [Epub ahead of print] No abstract available.

PMID:
29850837
3.

Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort.

Waszak SM, Northcott PA, Buchhalter I, Robinson GW, Sutter C, Groebner S, Grund KB, Brugières L, Jones DTW, Pajtler KW, Morrissy AS, Kool M, Sturm D, Chavez L, Ernst A, Brabetz S, Hain M, Zichner T, Segura-Wang M, Weischenfeldt J, Rausch T, Mardin BR, Zhou X, Baciu C, Lawerenz C, Chan JA, Varlet P, Guerrini-Rousseau L, Fults DW, Grajkowska W, Hauser P, Jabado N, Ra YS, Zitterbart K, Shringarpure SS, De La Vega FM, Bustamante CD, Ng HK, Perry A, MacDonald TJ, Hernáiz Driever P, Bendel AE, Bowers DC, McCowage G, Chintagumpala MM, Cohn R, Hassall T, Fleischhack G, Eggen T, Wesenberg F, Feychting M, Lannering B, Schüz J, Johansen C, Andersen TV, Röösli M, Kuehni CE, Grotzer M, Kjaerheim K, Monoranu CM, Archer TC, Duke E, Pomeroy SL, Shelagh R, Frank S, Sumerauer D, Scheurlen W, Ryzhova MV, Milde T, Kratz CP, Samuel D, Zhang J, Solomon DA, Marra M, Eils R, Bartram CR, von Hoff K, Rutkowski S, Ramaswamy V, Gilbertson RJ, Korshunov A, Taylor MD, Lichter P, Malkin D, Gajjar A, Korbel JO, Pfister SM.

Lancet Oncol. 2018 Jun;19(6):785-798. doi: 10.1016/S1470-2045(18)30242-0. Epub 2018 May 9.

4.

A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases.

Garzia L, Kijima N, Morrissy AS, De Antonellis P, Guerreiro-Stucklin A, Holgado BL, Wu X, Wang X, Parsons M, Zayne K, Manno A, Kuzan-Fischer C, Nor C, Donovan LK, Liu J, Qin L, Garancher A, Liu KW, Mansouri S, Luu B, Thompson YY, Ramaswamy V, Peacock J, Farooq H, Skowron P, Shih DJH, Li A, Ensan S, Robbins CS, Cybulsky M, Mitra S, Ma Y, Moore R, Mungall A, Cho YJ, Weiss WA, Chan JA, Hawkins CE, Massimino M, Jabado N, Zapotocky M, Sumerauer D, Bouffet E, Dirks P, Tabori U, Sorensen PHB, Brastianos PK, Aldape K, Jones SJM, Marra MA, Woodgett JR, Wechsler-Reya RJ, Fults DW, Taylor MD.

Cell. 2018 Feb 22;172(5):1050-1062.e14. doi: 10.1016/j.cell.2018.01.038. Erratum in: Cell. 2018 May 31;173(6):1549.

PMID:
29474906
5.

Application of 3-Dimensional Printing in a Case of Osteogenesis Imperfecta for Patient Education, Anatomic Understanding, Preoperative Planning, and Intraoperative Evaluation.

Eisenmenger LB, Wiggins RH 3rd, Fults DW 3rd, Huo EJ.

World Neurosurg. 2017 Nov;107:1049.e1-1049.e7. doi: 10.1016/j.wneu.2017.08.026. Epub 2017 Aug 18.

PMID:
28823657
6.

IGFBP2 expression predicts IDH-mutant glioma patient survival.

Huang LE, Cohen AL, Colman H, Jensen RL, Fults DW, Couldwell WT.

Oncotarget. 2017 Jan 3;8(1):191-202. doi: 10.18632/oncotarget.13329.

7.

Divergent clonal selection dominates medulloblastoma at recurrence.

Morrissy AS, Garzia L, Shih DJ, Zuyderduyn S, Huang X, Skowron P, Remke M, Cavalli FM, Ramaswamy V, Lindsay PE, Jelveh S, Donovan LK, Wang X, Luu B, Zayne K, Li Y, Mayoh C, Thiessen N, Mercier E, Mungall KL, Ma Y, Tse K, Zeng T, Shumansky K, Roth AJ, Shah S, Farooq H, Kijima N, Holgado BL, Lee JJ, Matan-Lithwick S, Liu J, Mack SC, Manno A, Michealraj KA, Nor C, Peacock J, Qin L, Reimand J, Rolider A, Thompson YY, Wu X, Pugh T, Ally A, Bilenky M, Butterfield YS, Carlsen R, Cheng Y, Chuah E, Corbett RD, Dhalla N, He A, Lee D, Li HI, Long W, Mayo M, Plettner P, Qian JQ, Schein JE, Tam A, Wong T, Birol I, Zhao Y, Faria CC, Pimentel J, Nunes S, Shalaby T, Grotzer M, Pollack IF, Hamilton RL, Li XN, Bendel AE, Fults DW, Walter AW, Kumabe T, Tominaga T, Collins VP, Cho YJ, Hoffman C, Lyden D, Wisoff JH, Garvin JH Jr, Stearns DS, Massimi L, Schüller U, Sterba J, Zitterbart K, Puget S, Ayrault O, Dunn SE, Tirapelli DP, Carlotti CG, Wheeler H, Hallahan AR, Ingram W, MacDonald TJ, Olson JJ, Van Meir EG, Lee JY, Wang KC, Kim SK, Cho BK, Pietsch T, Fleischhack G, Tippelt S, Ra YS, Bailey S, Lindsey JC, Clifford SC, Eberhart CG, Cooper MK, Packer RJ, Massimino M, Garre ML, Bartels U, Tabori U, Hawkins CE, Dirks P, Bouffet E, Rutka JT, Wechsler-Reya RJ, Weiss WA, Collier LS, Dupuy AJ, Korshunov A, Jones DT, Kool M, Northcott PA, Pfister SM, Largaespada DA, Mungall AJ, Moore RA, Jabado N, Bader GD, Jones SJ, Malkin D, Marra MA, Taylor MD.

Nature. 2016 Jan 21;529(7586):351-7. doi: 10.1038/nature16478. Epub 2016 Jan 13.

8.

Somatic cell transfer of c-Myc and Bcl-2 induces large-cell anaplastic medulloblastomas in mice.

Jenkins NC, Rao G, Eberhart CG, Pedone CA, Dubuc AM, Fults DW.

J Neurooncol. 2016 Feb;126(3):415-24. doi: 10.1007/s11060-015-1985-9. Epub 2015 Oct 30.

9.

Introduction. Neurooncology: update on therapeutic options.

Fults DW, Chen T, Bruce JN.

Neurosurg Focus. 2015 Mar;38(3):E1. doi: 10.3171/2015.1.FOCUS1515. No abstract available.

PMID:
25727218
10.

Genetic drivers of metastatic dissemination in sonic hedgehog medulloblastoma.

Jenkins NC, Kalra RR, Dubuc A, Sivakumar W, Pedone CA, Wu X, Taylor MD, Fults DW.

Acta Neuropathol Commun. 2014 Jul 25;2:85. doi: 10.1186/s40478-014-0085-y.

11.

Integrative genomics reveals molecular and clinical heterogeneity in central nervous system primitive neuroectodermal tumors in children.

Fults DW.

Transl Pediatr. 2012 Oct;1(2):63-4. doi: 10.3978/j.issn.2224-4336.2012.09.02. No abstract available.

12.

Glioblastoma presenting with steroid-induced pseudoregression of contrast enhancement on magnetic resonance imaging.

Mazur MD, Nguyen V, Fults DW.

Case Rep Neurol Med. 2012;2012:816873. doi: 10.1155/2012/816873. Epub 2012 Jul 11.

13.

Functional genomics identifies drivers of medulloblastoma dissemination.

Mumert M, Dubuc A, Wu X, Northcott PA, Chin SS, Pedone CA, Taylor MD, Fults DW.

Cancer Res. 2012 Oct 1;72(19):4944-53. doi: 10.1158/0008-5472.CAN-12-1629. Epub 2012 Aug 8.

14.

Clonal selection drives genetic divergence of metastatic medulloblastoma.

Wu X, Northcott PA, Dubuc A, Dupuy AJ, Shih DJ, Witt H, Croul S, Bouffet E, Fults DW, Eberhart CG, Garzia L, Van Meter T, Zagzag D, Jabado N, Schwartzentruber J, Majewski J, Scheetz TE, Pfister SM, Korshunov A, Li XN, Scherer SW, Cho YJ, Akagi K, MacDonald TJ, Koster J, McCabe MG, Sarver AL, Collins VP, Weiss WA, Largaespada DA, Collier LS, Taylor MD.

Nature. 2012 Feb 15;482(7386):529-33. doi: 10.1038/nature10825.

15.

WIP1 enhances tumor formation in a sonic hedgehog-dependent model of medulloblastoma.

Doucette TA, Yang Y, Pedone C, Kim JY, Dubuc A, Northcott PD, Taylor MD, Fults DW, Rao G.

Neurosurgery. 2012 Apr;70(4):1003-10; discussion 1010. doi: 10.1227/NEU.0b013e31823e5332.

16.

Brain wounds.

Taussky P, Fults DW.

J Neurosurg. 2011 Oct;115(4):872-3; author reply 873. doi: 10.3171/2011.5.JNS11733. Epub 2011 Aug 19. No abstract available.

PMID:
21854115
17.

The life of Rudolf Nissen: advancing surgery through science and principle.

Fults DW, Taussky P.

World J Surg. 2011 Jun;35(6):1402-8. doi: 10.1007/s00268-011-1047-1.

PMID:
21424871
18.

Bcl-2 promotes malignant progression in a PDGF-B-dependent murine model of oligodendroglioma.

Doucette T, Yang Y, Zhang W, Fuller GN, Suki D, Fults DW, Rao G.

Int J Cancer. 2011 Nov 1;129(9):2093-103. doi: 10.1002/ijc.25869. Epub 2011 Mar 4.

19.

The genetic landscape of the childhood cancer medulloblastoma.

Parsons DW, Li M, Zhang X, Jones S, Leary RJ, Lin JC, Boca SM, Carter H, Samayoa J, Bettegowda C, Gallia GL, Jallo GI, Binder ZA, Nikolsky Y, Hartigan J, Smith DR, Gerhard DS, Fults DW, VandenBerg S, Berger MS, Marie SK, Shinjo SM, Clara C, Phillips PC, Minturn JE, Biegel JA, Judkins AR, Resnick AC, Storm PB, Curran T, He Y, Rasheed BA, Friedman HS, Keir ST, McLendon R, Northcott PA, Taylor MD, Burger PC, Riggins GJ, Karchin R, Parmigiani G, Bigner DD, Yan H, Papadopoulos N, Vogelstein B, Kinzler KW, Velculescu VE.

Science. 2011 Jan 28;331(6016):435-9. doi: 10.1126/science.1198056. Epub 2010 Dec 16.

20.

Molecular therapy targeting Sonic hedgehog and hepatocyte growth factor signaling in a mouse model of medulloblastoma.

Coon V, Laukert T, Pedone CA, Laterra J, Kim KJ, Fults DW.

Mol Cancer Ther. 2010 Sep;9(9):2627-36. doi: 10.1158/1535-7163.MCT-10-0486. Epub 2010 Aug 31.

21.

Hepatocyte growth factor and sonic Hedgehog expression in cerebellar neural progenitor cells costimulate medulloblastoma initiation and growth.

Binning MJ, Niazi T, Pedone CA, Lal B, Eberhart CG, Kim KJ, Laterra J, Fults DW.

Cancer Res. 2008 Oct 1;68(19):7838-45. doi: 10.1158/0008-5472.CAN-08-1899.

22.

Recurrent cerebellar hemangioblastoma with enhancing tumor in the cyst wall: case report.

Bishop FS, Liu JK, Chin SS, Fults DW.

Neurosurgery. 2008 Jun;62(6):E1378-9; discussion E1379. doi: 10.1227/01.neu.0000333313.33296.02.

PMID:
18824960
23.

Use of resorbable collagen dural substitutes in the presence of cranial and spinal infections-report of 3 cases.

McCall TD, Fults DW, Schmidt RH.

Surg Neurol. 2008 Jul;70(1):92-6; discussion 96-7. doi: 10.1016/j.surneu.2007.04.007. Epub 2008 Feb 11.

PMID:
18262619
24.
25.

N-myc can substitute for insulin-like growth factor signaling in a mouse model of sonic hedgehog-induced medulloblastoma.

Browd SR, Kenney AM, Gottfried ON, Yoon JW, Walterhouse D, Pedone CA, Fults DW.

Cancer Res. 2006 Mar 1;66(5):2666-72.

26.

Tuberous sclerosis: a syndrome of incomplete tumor suppression.

McCall T, Chin SS, Salzman KL, Fults DW.

Neurosurg Focus. 2006 Jan 15;20(1):E3. Review.

PMID:
16459993
27.

Modeling medulloblastoma with genetically engineered mice.

Fults DW.

Neurosurg Focus. 2005 Nov 15;19(5):E7. Review.

PMID:
16398471
28.

Molecular, genetic, and cellular pathogenesis of neurofibromas and surgical implications.

Gottfried ON, Viskochil DH, Fults DW, Couldwell WT.

Neurosurgery. 2006 Jan;58(1):1-16; discussion 1-16. Review.

PMID:
16385324
29.

Identification of OTX2 as a medulloblastoma oncogene whose product can be targeted by all-trans retinoic acid.

Di C, Liao S, Adamson DC, Parrett TJ, Broderick DK, Shi Q, Lengauer C, Cummins JM, Velculescu VE, Fults DW, McLendon RE, Bigner DD, Yan H.

Cancer Res. 2005 Feb 1;65(3):919-24.

30.

Mutations of PIK3CA in anaplastic oligodendrogliomas, high-grade astrocytomas, and medulloblastomas.

Broderick DK, Di C, Parrett TJ, Samuels YR, Cummins JM, McLendon RE, Fults DW, Velculescu VE, Bigner DD, Yan H.

Cancer Res. 2004 Aug 1;64(15):5048-50.

31.

Sonic hedgehog and insulin-like growth factor signaling synergize to induce medulloblastoma formation from nestin-expressing neural progenitors in mice.

Rao G, Pedone CA, Del Valle L, Reiss K, Holland EC, Fults DW.

Oncogene. 2004 Aug 12;23(36):6156-62.

PMID:
15195141
32.

Spontaneous hemorrhage associated with a pilomyxoid astrocytoma. Case report.

Gottfried ON, Fults DW, Townsend JJ, Couldwell WT.

J Neurosurg. 2003 Aug;99(2):416-20. Review.

PMID:
12924720
33.

c-Myc enhances sonic hedgehog-induced medulloblastoma formation from nestin-expressing neural progenitors in mice.

Rao G, Pedone CA, Coffin CM, Holland EC, Fults DW.

Neoplasia. 2003 May-Jun;5(3):198-204. doi: 10.1016/S1476-5586(03)80052-0.

34.

Rig is a novel Ras-related protein and potential neural tumor suppressor.

Ellis CA, Vos MD, Howell H, Vallecorsa T, Fults DW, Clark GJ.

Proc Natl Acad Sci U S A. 2002 Jul 23;99(15):9876-81. Epub 2002 Jul 9.

35.

Sporadic medulloblastomas contain PTCH mutations.

Raffel C, Jenkins RB, Frederick L, Hebrink D, Alderete B, Fults DW, James CD.

Cancer Res. 1997 Mar 1;57(5):842-5.

36.

Astrocytoma and pineoblastoma arising sequentially in the fourth ventricle of the same patient. Case report and molecular analysis.

Brockmeyer DL, Walker ML, Thompson G, Fults DW.

Pediatr Neurosurg. 1997 Jan;26(1):36-40.

PMID:
9361116
37.

Rek, a gene expressed in retina and brain, encodes a receptor tyrosine kinase of the Axl/Tyro3 family.

Biscardi JS, Denhez F, Buehler GF, Chesnutt DA, Baragona SC, O'Bryan JP, Der CJ, Fiordalisi JJ, Fults DW, Maness PF.

J Biol Chem. 1996 Nov 15;271(46):29049-59.

38.

Loss of heterozygosity on chromosome 10 in human glioblastoma multiforme.

Fujimoto M, Fults DW, Thomas GA, Nakamura Y, Heilbrun MP, White R, Story JL, Naylor SL, Kagan-Hallet KS, Sheridan PJ.

Genomics. 1989 Feb;4(2):210-4.

PMID:
2544511
39.

c-src and other proto-oncogenes implicated in neuronal differentiation.

Ingraham CA, Cox ME, Ward DC, Fults DW, Maness PF.

Mol Chem Neuropathol. 1989 Feb;10(1):1-14. Review.

PMID:
2472150
40.

An early developmental phase of pp60c-src expression in the neural ectoderm.

Maness PF, Sorge LK, Fults DW.

Dev Biol. 1986 Sep;117(1):83-9.

PMID:
3527816
41.

pp60c-src in the developing cerebellum.

Fults DW, Towle AC, Lauder JM, Maness PF.

Mol Cell Biol. 1985 Jan;5(1):27-32.

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