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Items: 1 to 50 of 56

1.

Lipid droplet quantification based on iterative image processing.

Exner T, Beretta CA, Gao Q, Afting C, Romero-Brey I, Bartenschlager R, Fehring L, Poppelreuther M, Füllekrug J.

J Lipid Res. 2019 Jul;60(7):1333-1344. doi: 10.1194/jlr.D092841. Epub 2019 Mar 29.

PMID:
30926625
2.

An alternative membrane topology permits lipid droplet localization of peroxisomal fatty acyl-CoA reductase 1.

Exner T, Romero-Brey I, Yifrach E, Rivera-Monroy J, Schrul B, Zouboulis CC, Stremmel W, Honsho M, Bartenschlager R, Zalckvar E, Poppelreuther M, Füllekrug J.

J Cell Sci. 2019 Mar 18;132(6). pii: jcs223016. doi: 10.1242/jcs.223016.

3.

Long-chain acyl-CoA synthetase 1 interacts with key proteins that activate and direct fatty acids into niche hepatic pathways.

Young PA, Senkal CE, Suchanek AL, Grevengoed TJ, Lin DD, Zhao L, Crunk AE, Klett EL, Füllekrug J, Obeid LM, Coleman RA.

J Biol Chem. 2018 Oct 26;293(43):16724-16740. doi: 10.1074/jbc.RA118.004049. Epub 2018 Sep 6.

4.

The metabolic capacity of lipid droplet localized acyl-CoA synthetase 3 is not sufficient to support local triglyceride synthesis independent of the endoplasmic reticulum in A431 cells.

Poppelreuther M, Sander S, Minden F, Dietz MS, Exner T, Du C, Zhang I, Ehehalt F, Knüppel L, Domschke S, Badenhop A, Staudacher S, Ehehalt R, Stremmel W, Thiele C, Heilemann M, Füllekrug J.

Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Jun;1863(6):614-624. doi: 10.1016/j.bbalip.2018.03.003. Epub 2018 Mar 9.

PMID:
29526665
5.

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition.

Doll S, Proneth B, Tyurina YY, Panzilius E, Kobayashi S, Ingold I, Irmler M, Beckers J, Aichler M, Walch A, Prokisch H, Trümbach D, Mao G, Qu F, Bayir H, Füllekrug J, Scheel CH, Wurst W, Schick JA, Kagan VE, Angeli JP, Conrad M.

Nat Chem Biol. 2017 Jan;13(1):91-98. doi: 10.1038/nchembio.2239. Epub 2016 Nov 14.

6.

Generation and functional characterization of epithelial cells with stable expression of SLC26A9 Cl- channels.

Salomon JJ, Spahn S, Wang X, Füllekrug J, Bertrand CA, Mall MA.

Am J Physiol Lung Cell Mol Physiol. 2016 Apr 1;310(7):L593-602. doi: 10.1152/ajplung.00321.2015. Epub 2016 Jan 22.

7.

Measurement of Long-Chain Fatty Acyl-CoA Synthetase Activity.

Füllekrug J, Poppelreuther M.

Methods Mol Biol. 2016;1376:43-53. doi: 10.1007/978-1-4939-3170-5_5.

PMID:
26552674
8.

Protein mediated fatty acid uptake: synergy between CD36/FAT-facilitated transport and acyl-CoA synthetase-driven metabolism.

Schneider H, Staudacher S, Poppelreuther M, Stremmel W, Ehehalt R, Füllekrug J.

Arch Biochem Biophys. 2014 Mar 15;546:8-18. doi: 10.1016/j.abb.2014.01.025. Epub 2014 Feb 4.

PMID:
24503477
9.

Differentially localized acyl-CoA synthetase 4 isoenzymes mediate the metabolic channeling of fatty acids towards phosphatidylinositol.

Küch EM, Vellaramkalayil R, Zhang I, Lehnen D, Brügger B, Sreemmel W, Ehehalt R, Poppelreuther M, Füllekrug J.

Biochim Biophys Acta. 2014 Feb;1841(2):227-39.

PMID:
24201376
10.

Sensory memory of illusory depth in structure-from-motion.

Pastukhov A, Lissner A, Füllekrug J, Braun J.

Atten Percept Psychophys. 2014 Jan;76(1):123-32. doi: 10.3758/s13414-013-0557-3.

PMID:
24097015
11.

Sensory memory of structure-from-motion is shape-specific.

Pastukhov A, Füllekrug J, Braun J.

Atten Percept Psychophys. 2013 Aug;75(6):1215-29. doi: 10.3758/s13414-013-0471-8.

PMID:
23673611
12.

Outlook: membrane junctions enable the metabolic trapping of fatty acids by intracellular acyl-CoA synthetases.

Füllekrug J, Ehehalt R, Poppelreuther M.

Front Physiol. 2012 Oct 10;3:401. doi: 10.3389/fphys.2012.00401. eCollection 2012.

13.
14.

The N-terminal region of acyl-CoA synthetase 3 is essential for both the localization on lipid droplets and the function in fatty acid uptake.

Poppelreuther M, Rudolph B, Du C, Großmann R, Becker M, Thiele C, Ehehalt R, Füllekrug J.

J Lipid Res. 2012 May;53(5):888-900. doi: 10.1194/jlr.M024562. Epub 2012 Feb 22.

15.

Enhanced fatty acid oxidation and FATP4 protein expression after endurance exercise training in human skeletal muscle.

Jeppesen J, Jordy AB, Sjøberg KA, Füllekrug J, Stahl A, Nybo L, Kiens B.

PLoS One. 2012;7(1):e29391. doi: 10.1371/journal.pone.0029391. Epub 2012 Jan 3.

16.

Overexpression of CD36 and acyl-CoA synthetases FATP2, FATP4 and ACSL1 increases fatty acid uptake in human hepatoma cells.

Krammer J, Digel M, Ehehalt F, Stremmel W, Füllekrug J, Ehehalt R.

Int J Med Sci. 2011;8(7):599-614. Epub 2011 Oct 7.

17.

Adipocyte-specific inactivation of Acyl-CoA synthetase fatty acid transport protein 4 (Fatp4) in mice causes adipose hypertrophy and alterations in metabolism of complex lipids under high fat diet.

Lenz LS, Marx J, Chamulitrat W, Kaiser I, Gröne HJ, Liebisch G, Schmitz G, Elsing C, Straub BK, Füllekrug J, Stremmel W, Herrmann T.

J Biol Chem. 2011 Oct 14;286(41):35578-87. doi: 10.1074/jbc.M111.226530. Epub 2011 Jul 31.

18.

FATP4 contributes as an enzyme to the basal and insulin-mediated fatty acid uptake of C₂C₁₂ muscle cells.

Digel M, Staffer S, Ehehalt F, Stremmel W, Ehehalt R, Füllekrug J.

Am J Physiol Endocrinol Metab. 2011 Nov;301(5):E785-96. doi: 10.1152/ajpendo.00079.2011. Epub 2011 Jul 12.

19.

Silybin and dehydrosilybin decrease glucose uptake by inhibiting GLUT proteins.

Zhan T, Digel M, Küch EM, Stremmel W, Füllekrug J.

J Cell Biochem. 2011 Mar;112(3):849-59. doi: 10.1002/jcb.22984.

PMID:
21328458
20.

Lipid based therapy for ulcerative colitis-modulation of intestinal mucus membrane phospholipids as a tool to influence inflammation.

Schneider H, Braun A, Füllekrug J, Stremmel W, Ehehalt R.

Int J Mol Sci. 2010 Oct 25;11(10):4149-64. doi: 10.3390/ijms11104149. Review.

21.

Knockdown of caveolin-1 decreases activity of breast cancer resistance protein (BCRP/ABCG2) and increases chemotherapeutic sensitivity.

Herzog M, Storch CH, Gut P, Kotlyar D, Füllekrug J, Ehehalt R, Haefeli WE, Weiss J.

Naunyn Schmiedebergs Arch Pharmacol. 2011 Jan;383(1):1-11. doi: 10.1007/s00210-010-0568-8. Epub 2010 Oct 10.

PMID:
20936466
22.

Phosphatidylcholine as a constituent in the colonic mucosal barrier--physiological and clinical relevance.

Ehehalt R, Braun A, Karner M, Füllekrug J, Stremmel W.

Biochim Biophys Acta. 2010 Sep;1801(9):983-93. doi: 10.1016/j.bbalip.2010.05.014. Epub 2010 Jun 4. Review.

PMID:
20595010
23.

Genetic analysis of BIRC4/XIAP as a putative modifier gene of Wilson disease.

Weiss KH, Runz H, Noe B, Gotthardt DN, Merle U, Ferenci P, Stremmel W, Füllekrug J.

J Inherit Metab Dis. 2010 Dec;33 Suppl 3:S233-40. doi: 10.1007/s10545-010-9123-5. Epub 2010 Jun 2.

PMID:
20517649
24.

Fatty acid- and cholesterol transporter protein expression along the human intestinal tract.

Masson CJ, Plat J, Mensink RP, Namiot A, Kisielewski W, Namiot Z, Füllekrug J, Ehehalt R, Glatz JF, Pelsers MM.

PLoS One. 2010 Apr 29;5(4):e10380. doi: 10.1371/journal.pone.0010380.

25.

Lipid droplets lighting up: insights from live microscopy.

Digel M, Ehehalt R, Füllekrug J.

FEBS Lett. 2010 Jun 3;584(11):2168-75. doi: 10.1016/j.febslet.2010.03.035. Epub 2010 Mar 30. Review.

26.

TNF-alpha-induced up-regulation of pro-inflammatory cytokines is reduced by phosphatidylcholine in intestinal epithelial cells.

Treede I, Braun A, Jeliaskova P, Giese T, Füllekrug J, Griffiths G, Stremmel W, Ehehalt R.

BMC Gastroenterol. 2009 Jul 13;9:53. doi: 10.1186/1471-230X-9-53.

27.

Acyl-CoA synthetases: fatty acid uptake and metabolic channeling.

Digel M, Ehehalt R, Stremmel W, Füllekrug J.

Mol Cell Biochem. 2009 Jun;326(1-2):23-8. doi: 10.1007/s11010-008-0003-3. Epub 2008 Dec 30.

PMID:
19115050
28.

Copper-induced translocation of the Wilson disease protein ATP7B independent of Murr1/COMMD1 and Rab7.

Weiss KH, Lozoya JC, Tuma S, Gotthardt D, Reichert J, Ehehalt R, Stremmel W, Füllekrug J.

Am J Pathol. 2008 Dec;173(6):1783-94. doi: 10.2353/ajpath.2008.071134. Epub 2008 Oct 30.

29.

Uptake of long chain fatty acids is regulated by dynamic interaction of FAT/CD36 with cholesterol/sphingolipid enriched microdomains (lipid rafts).

Ehehalt R, Sparla R, Kulaksiz H, Herrmann T, Füllekrug J, Stremmel W.

BMC Cell Biol. 2008 Aug 13;9:45. doi: 10.1186/1471-2121-9-45.

30.

Localization of the Wilson disease protein in murine intestine.

Weiss KH, Wurz J, Gotthardt D, Merle U, Stremmel W, Füllekrug J.

J Anat. 2008 Sep;213(3):232-40. doi: 10.1111/j.1469-7580.2008.00954.x. Epub 2008 Jul 25.

31.

Ceramide and raft signaling are linked with each other in UVA radiation-induced gene expression.

Grether-Beck S, Salahshour-Fard M, Timmer A, Brenden H, Felsner I, Walli R, Füllekrug J, Krutmann J.

Oncogene. 2008 Aug 14;27(35):4768-78. doi: 10.1038/onc.2008.116. Epub 2008 Apr 28.

PMID:
18438433
32.
33.

Contributions of galectin-3 and -9 to epithelial cell adhesion analyzed by single cell force spectroscopy.

Friedrichs J, Torkko JM, Helenius J, Teräväinen TP, Füllekrug J, Muller DJ, Simons K, Manninen A.

J Biol Chem. 2007 Oct 5;282(40):29375-83. Epub 2007 Aug 3.

34.

Anti-inflammatory effects of phosphatidylcholine.

Treede I, Braun A, Sparla R, Kühnel M, Giese T, Turner JR, Anes E, Kulaksiz H, Füllekrug J, Stremmel W, Griffiths G, Ehehalt R.

J Biol Chem. 2007 Sep 14;282(37):27155-64. Epub 2007 Jul 18.

35.

Rer1p competes with APH-1 for binding to nicastrin and regulates gamma-secretase complex assembly in the early secretory pathway.

Spasic D, Raemaekers T, Dillen K, Declerck I, Baert V, Serneels L, Füllekrug J, Annaert W.

J Cell Biol. 2007 Feb 26;176(5):629-40.

36.

FAPP2, cilium formation, and compartmentalization of the apical membrane in polarized Madin-Darby canine kidney (MDCK) cells.

Vieira OV, Gaus K, Verkade P, Fullekrug J, Vaz WL, Simons K.

Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18556-61. Epub 2006 Nov 20.

37.

Cellular uptake of fatty acids driven by the ER-localized acyl-CoA synthetase FATP4.

Milger K, Herrmann T, Becker C, Gotthardt D, Zickwolf J, Ehehalt R, Watkins PA, Stremmel W, Füllekrug J.

J Cell Sci. 2006 Nov 15;119(Pt 22):4678-88. Epub 2006 Oct 24.

38.

Copper toxicosis gene MURR1 is not changed in Wilson disease patients with normal blood ceruloplasmin levels.

Weiss KH, Merle U, Schaefer M, Ferenci P, Fullekrug J, Stremmel W.

World J Gastroenterol. 2006 Apr 14;12(14):2239-42.

39.
40.

Translocation of long chain fatty acids across the plasma membrane--lipid rafts and fatty acid transport proteins.

Ehehalt R, Füllekrug J, Pohl J, Ring A, Herrmann T, Stremmel W.

Mol Cell Biochem. 2006 Mar;284(1-2):135-40. Epub 2006 Feb 14. Review. Erratum in: Mol Cell Biochem. 2007 May;299(1-2):1-3.

PMID:
16477381
41.

Caveolin-1 is not essential for biosynthetic apical membrane transport.

Manninen A, Verkade P, Le Lay S, Torkko J, Kasper M, Füllekrug J, Simons K.

Mol Cell Biol. 2005 Nov;25(22):10087-96.

42.

Gp135/podocalyxin and NHERF-2 participate in the formation of a preapical domain during polarization of MDCK cells.

Meder D, Shevchenko A, Simons K, Füllekrug J.

J Cell Biol. 2005 Jan 17;168(2):303-13. Epub 2005 Jan 10.

43.

Lipid rafts and apical membrane traffic.

Füllekrug J, Simons K.

Ann N Y Acad Sci. 2004 Apr;1014:164-9. Review.

PMID:
15153431
44.

Generation of single and double knockdowns in polarized epithelial cells by retrovirus-mediated RNA interference.

Schuck S, Manninen A, Honsho M, Füllekrug J, Simons K.

Proc Natl Acad Sci U S A. 2004 Apr 6;101(14):4912-7. Epub 2004 Mar 29.

45.

Glycosylation and protein transport.

Scheiffele P, Füllekrug J.

Essays Biochem. 2000;36:27-35. Review.

PMID:
12471900
46.

Identification and characterization of a novel human plant pathogenesis-related protein that localizes to lipid-enriched microdomains in the Golgi complex.

Eberle HB, Serrano RL, Füllekrug J, Schlosser A, Lehmann WD, Lottspeich F, Kaloyanova D, Wieland FT, Helms JB.

J Cell Sci. 2002 Feb 15;115(Pt 4):827-38.

47.
48.

VIP36 localisation to the early secretory pathway.

Füllekrug J, Scheiffele P, Simons K.

J Cell Sci. 1999 Sep;112 ( Pt 17):2813-21.

49.

Localization and recycling of gp27 (hp24gamma3): complex formation with other p24 family members.

Füllekrug J, Suganuma T, Tang BL, Hong W, Storrie B, Nilsson T.

Mol Biol Cell. 1999 Jun;10(6):1939-55.

50.

Protein sorting in the Golgi complex.

Füllekrug J, Nilsson T.

Biochim Biophys Acta. 1998 Aug 14;1404(1-2):77-84. Review.

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