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Items: 50


Pediatric Hypereosinophilia: Characteristics, Clinical Manifestations, and Diagnoses.

Burris D, Rosenberg CE, Schwartz JT, Zhang Y, Eby MD, Abonia JP, Fulkerson PC.

J Allergy Clin Immunol Pract. 2019 May 22. pii: S2213-2198(19)30466-0. doi: 10.1016/j.jaip.2019.05.011. [Epub ahead of print]


Increasing Rates of Diagnosis, Substantial Co-Occurrence, and Variable Treatment Patterns of Eosinophilic Gastritis, Gastroenteritis, and Colitis Based on 10-Year Data Across a Multicenter Consortium.

Pesek RD, Reed CC, Muir AB, Fulkerson PC, Menard-Katcher C, Falk GW, Kuhl J, Martin EK, Magier AZ, Ahmed F, Demarshall M, Gupta A, Gross J, Ashorobi T, Carpenter CL, Krischer JP, Gonsalves N, Spergel JM, Gupta SK, Furuta GT, Rothenberg ME, Dellon ES; Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR).

Am J Gastroenterol. 2019 Jun;114(6):984-994. doi: 10.14309/ajg.0000000000000228.


Eosinophil progenitor levels correlate with tissue pathology in pediatric eosinophilic esophagitis.

Schwartz JT, Morris DW, Collins MH, Rothenberg ME, Fulkerson PC.

J Allergy Clin Immunol. 2019 Mar;143(3):1221-1224.e3. doi: 10.1016/j.jaci.2018.10.036. Epub 2018 Nov 9. No abstract available.


An Approach to the Evaluation of Persistent Hypereosinophilia in Pediatric Patients.

Schwartz JT, Fulkerson PC.

Front Immunol. 2018 Sep 3;9:1944. doi: 10.3389/fimmu.2018.01944. eCollection 2018. Review.


Chromatin Preparation from Murine Eosinophils for Genome-Wide Analyses.

Bouffi C, Barski A, Fulkerson PC.

Methods Mol Biol. 2018;1799:265-274. doi: 10.1007/978-1-4939-7896-0_20.


Siglec-8 on murine eosinophils: A new model for an old target.

Fulkerson PC.

J Leukoc Biol. 2018 Jul;104(1):7-9. doi: 10.1002/JLB.2CE0318-105R. Epub 2018 May 31. No abstract available.


Esophageal IgG4 levels correlate with histopathologic and transcriptomic features in eosinophilic esophagitis.

Rosenberg CE, Mingler MK, Caldwell JM, Collins MH, Fulkerson PC, Morris DW, Mukkada VA, Putnam PE, Shoda T, Wen T, Rothenberg ME.

Allergy. 2018 Sep;73(9):1892-1901. doi: 10.1111/all.13486. Epub 2018 Jun 17.


Reuse of public, genome-wide, murine eosinophil expression data for hypotheses development.

Grace JO, Malik A, Reichman H, Munitz A, Barski A, Fulkerson PC.

J Leukoc Biol. 2018 Jul;104(1):185-193. doi: 10.1002/JLB.1MA1117-444R. Epub 2018 May 14.


Eosinophilic esophagitis: Time to classify into endotypes?

Ferguson AE, Fulkerson PC.

J Allergy Clin Immunol. 2018 Jul;142(1):71-72. doi: 10.1016/j.jaci.2018.04.025. Epub 2018 May 8. No abstract available.


Eosinophil Development, Disease Involvement, and Therapeutic Suppression.

Fulkerson PC, Rothenberg ME.

Adv Immunol. 2018;138:1-34. doi: 10.1016/ Epub 2018 Apr 22.


Revisiting the NIH Taskforce on the Research needs of Eosinophil-Associated Diseases (RE-TREAD).

Khoury P, Akuthota P, Ackerman SJ, Arron JR, Bochner BS, Collins MH, Kahn JE, Fulkerson PC, Gleich GJ, Gopal-Srivastava R, Jacobsen EA, Leiferman KM, Francesca LS, Mathur SK, Minnicozzi M, Prussin C, Rothenberg ME, Roufosse F, Sable K, Simon D, Simon HU, Spencer LA, Steinfeld J, Wardlaw AJ, Wechsler ME, Weller PF, Klion AD.

J Leukoc Biol. 2018 Jul;104(1):69-83. doi: 10.1002/JLB.5MR0118-028R. Epub 2018 Apr 19. Review.


Pediatric Eosinophilic Esophagitis Endotypes: Are We Closer to Predicting Treatment Response?

Ferguson AE, Mukkada VA, Fulkerson PC.

Clin Rev Allergy Immunol. 2018 Aug;55(1):43-55. doi: 10.1007/s12016-017-8658-8. Review.


Vaccinations in immunosuppressive-dependent pediatric inflammatory bowel disease.

Nguyen HT, Minar P, Jackson K, Fulkerson PC.

World J Gastroenterol. 2017 Nov 14;23(42):7644-7652. doi: 10.3748/wjg.v23.i42.7644.


Transcription Factors in Eosinophil Development and As Therapeutic Targets.

Fulkerson PC.

Front Med (Lausanne). 2017 Jul 24;4:115. doi: 10.3389/fmed.2017.00115. eCollection 2017. Review.


CD300f:IL-5 cross-talk inhibits adipose tissue eosinophil homing and subsequent IL-4 production.

Rozenberg P, Reichman H, Zab-Bar I, Itan M, Pasmanik-Chor M, Bouffi C, Qimron U, Bachelet I, Fulkerson PC, Rothenberg ME, Munitz A.

Sci Rep. 2017 Jul 19;7(1):5922. doi: 10.1038/s41598-017-06397-4.


In Memory and Celebration: Dr. James J. Lee.

Rosenberg HF, Fryer AD, Munitz A, Bochner BS, Jacoby DB, Levi-Schaffer F, Gleich GJ, Furuta GT, Rothenberg ME, Lacy P, Fulkerson PC, Hogan SP, Ackerman SJ, Foster PS.

Clin Exp Allergy. 2017 Jul;47(7):980-981. doi: 10.1111/cea.12959. No abstract available.


Eosinophil progenitor levels are increased in patients with active pediatric eosinophilic esophagitis.

Morris DW, Stucke EM, Martin LJ, Abonia JP, Mukkada VA, Putnam PE, Rothenberg ME, Fulkerson PC.

J Allergy Clin Immunol. 2016 Sep;138(3):915-918.e5. doi: 10.1016/j.jaci.2016.03.027. Epub 2016 May 16. No abstract available.


Transcription Factor Repertoire of Homeostatic Eosinophilopoiesis.

Bouffi C, Kartashov AV, Schollaert KL, Chen X, Bacon WC, Weirauch MT, Barski A, Fulkerson PC.

J Immunol. 2015 Sep 15;195(6):2683-95. doi: 10.4049/jimmunol.1500510. Epub 2015 Aug 12.


Identification of a negative regulatory role for spi-C in the murine B cell lineage.

Li SK, Solomon LA, Fulkerson PC, DeKoter RP.

J Immunol. 2015 Apr 15;194(8):3798-807. doi: 10.4049/jimmunol.1402432. Epub 2015 Mar 13.


Hospital admission associates with higher total IgE level in pediatric patients with asthma.

Sherenian MG, Wang Y, Fulkerson PC.

J Allergy Clin Immunol Pract. 2015 Jul-Aug;3(4):602-3.e1. doi: 10.1016/j.jaip.2015.01.014. Epub 2015 Feb 25. No abstract available.


Differential control of CD4(+) T-cell subsets by the PD-1/PD-L1 axis in a mouse model of allergic asthma.

McAlees JW, Lajoie S, Dienger K, Sproles AA, Richgels PK, Yang Y, Khodoun M, Azuma M, Yagita H, Fulkerson PC, Wills-Karp M, Lewkowich IP.

Eur J Immunol. 2015 Apr;45(4):1019-29. doi: 10.1002/eji.201444778. Epub 2015 Feb 26.


Generation of eosinophils from cryopreserved murine bone marrow cells.

Schollaert KL, Stephens MR, Gray JK, Fulkerson PC.

PLoS One. 2014 Dec 31;9(12):e116141. doi: 10.1371/journal.pone.0116141. eCollection 2014.


IL-5 triggers a cooperative cytokine network that promotes eosinophil precursor maturation.

Fulkerson PC, Schollaert KL, Bouffi C, Rothenberg ME.

J Immunol. 2014 Oct 15;193(8):4043-52. doi: 10.4049/jimmunol.1400732. Epub 2014 Sep 17.


IL-33 markedly activates murine eosinophils by an NF-κB-dependent mechanism differentially dependent upon an IL-4-driven autoinflammatory loop.

Bouffi C, Rochman M, Zust CB, Stucke EM, Kartashov A, Fulkerson PC, Barski A, Rothenberg ME.

J Immunol. 2013 Oct 15;191(8):4317-25. doi: 10.4049/jimmunol.1301465. Epub 2013 Sep 16.


News Beyond Our Pages.

Rothenberg ME, Bousquet J, Fulkerson PC.

J Allergy Clin Immunol. 2013 Sep;132(3):513-514. doi: 10.1016/j.jaci.2013.07.025. Epub 2013 Aug 27. No abstract available.


Expanding the paradigm of eosinophilic esophagitis: mast cells and IL-9.

Wang YH, Hogan SP, Fulkerson PC, Abonia JP, Rothenberg ME.

J Allergy Clin Immunol. 2013 Jun;131(6):1583-5. doi: 10.1016/j.jaci.2013.04.010. No abstract available.


Eosinophil adoptive transfer system to directly evaluate pulmonary eosinophil trafficking in vivo.

Wen T, Besse JA, Mingler MK, Fulkerson PC, Rothenberg ME.

Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):6067-72. doi: 10.1073/pnas.1220572110. Epub 2013 Mar 27.


Targeted ablation of miR-21 decreases murine eosinophil progenitor cell growth.

Lu TX, Lim EJ, Itskovich S, Besse JA, Plassard AJ, Mingler MK, Rothenberg JA, Fulkerson PC, Aronow BJ, Rothenberg ME.

PLoS One. 2013;8(3):e59397. doi: 10.1371/journal.pone.0059397. Epub 2013 Mar 22.


Targeting eosinophils in allergy, inflammation and beyond.

Fulkerson PC, Rothenberg ME.

Nat Rev Drug Discov. 2013 Feb;12(2):117-29. doi: 10.1038/nrd3838. Epub 2013 Jan 21. Review.


MiR-223 deficiency increases eosinophil progenitor proliferation.

Lu TX, Lim EJ, Besse JA, Itskovich S, Plassard AJ, Fulkerson PC, Aronow BJ, Rothenberg ME.

J Immunol. 2013 Feb 15;190(4):1576-82. doi: 10.4049/jimmunol.1202897. Epub 2013 Jan 16.


Eosinophils in infection and intestinal immunity.

Hogan SP, Waddell A, Fulkerson PC.

Curr Opin Gastroenterol. 2013 Jan;29(1):7-14. doi: 10.1097/MOG.0b013e32835ab29a. Review.


Novel targeted therapies for eosinophilic disorders.

Wechsler ME, Fulkerson PC, Bochner BS, Gauvreau GM, Gleich GJ, Henkel T, Kolbeck R, Mathur SK, Ortega H, Patel J, Prussin C, Renzi P, Rothenberg ME, Roufosse F, Simon D, Simon HU, Wardlaw A, Weller PF, Klion AD.

J Allergy Clin Immunol. 2012 Sep;130(3):563-71. doi: 10.1016/j.jaci.2012.07.027. Review.


In vivo regulation of TGF-β by R-Ras2 revealed through loss of the RasGAP protein NF1.

Patmore DM, Welch S, Fulkerson PC, Wu J, Choi K, Eaves D, Kordich JJ, Collins MH, Cripe TP, Ratner N.

Cancer Res. 2012 Oct 15;72(20):5317-27. doi: 10.1158/0008-5472.CAN-12-1972. Epub 2012 Aug 23.


IL-13 induces esophageal remodeling and gene expression by an eosinophil-independent, IL-13R alpha 2-inhibited pathway.

Zuo L, Fulkerson PC, Finkelman FD, Mingler M, Fischetti CA, Blanchard C, Rothenberg ME.

J Immunol. 2010 Jul 1;185(1):660-9. doi: 10.4049/jimmunol.1000471. Epub 2010 Jun 11.


Origin, regulation and physiological function of intestinal oeosinophils.

Fulkerson PC, Rothenberg ME.

Best Pract Res Clin Gastroenterol. 2008;22(3):411-23. doi: 10.1016/j.bpg.2007.10.023. Review.


Esophageal remodeling develops as a consequence of tissue specific IL-5-induced eosinophilia.

Mishra A, Wang M, Pemmaraju VR, Collins MH, Fulkerson PC, Abonia JP, Blanchard C, Putnam PE, Rothenberg ME.

Gastroenterology. 2008 Jan;134(1):204-14. doi: 10.1053/j.gastro.2007.10.002. Epub 2007 Oct 5.


Eosinophils and CCR3 regulate interleukin-13 transgene-induced pulmonary remodeling.

Fulkerson PC, Fischetti CA, Rothenberg ME.

Am J Pathol. 2006 Dec;169(6):2117-26.


A central regulatory role for eosinophils and the eotaxin/CCR3 axis in chronic experimental allergic airway inflammation.

Fulkerson PC, Fischetti CA, McBride ML, Hassman LM, Hogan SP, Rothenberg ME.

Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16418-23. Epub 2006 Oct 23.


Persistent effects induced by IL-13 in the lung.

Fulkerson PC, Fischetti CA, Hassman LM, Nikolaidis NM, Rothenberg ME.

Am J Respir Cell Mol Biol. 2006 Sep;35(3):337-46. Epub 2006 Apr 27.


Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis.

Blanchard C, Wang N, Stringer KF, Mishra A, Fulkerson PC, Abonia JP, Jameson SC, Kirby C, Konikoff MR, Collins MH, Cohen MB, Akers R, Hogan SP, Assa'ad AH, Putnam PE, Aronow BJ, Rothenberg ME.

J Clin Invest. 2006 Feb;116(2):536-47.


Building a better mouse model: experimental models of chronic asthma.

Fulkerson PC, Rothenberg ME, Hogan SP.

Clin Exp Allergy. 2005 Oct;35(10):1251-3. No abstract available.


CXCL9 inhibits eosinophil responses by a CCR3- and Rac2-dependent mechanism.

Fulkerson PC, Zhu H, Williams DA, Zimmermann N, Rothenberg ME.

Blood. 2005 Jul 15;106(2):436-43. Epub 2005 Mar 31.


Expression and regulation of small proline-rich protein 2 in allergic inflammation.

Zimmermann N, Doepker MP, Witte DP, Stringer KF, Fulkerson PC, Pope SM, Brandt EB, Mishra A, King NE, Nikolaidis NM, Wills-Karp M, Finkelman FD, Rothenberg ME.

Am J Respir Cell Mol Biol. 2005 May;32(5):428-35. Epub 2005 Feb 24.


Identification of a cooperative mechanism involving interleukin-13 and eotaxin-2 in experimental allergic lung inflammation.

Pope SM, Fulkerson PC, Blanchard C, Akei HS, Nikolaidis NM, Zimmermann N, Molkentin JD, Rothenberg ME.

J Biol Chem. 2005 Apr 8;280(14):13952-61. Epub 2005 Jan 12.


Pulmonary chemokine expression is coordinately regulated by STAT1, STAT6, and IFN-gamma.

Fulkerson PC, Zimmermann N, Hassman LM, Finkelman FD, Rothenberg ME.

J Immunol. 2004 Dec 15;173(12):7565-74.


Expression and regulation of a disintegrin and metalloproteinase (ADAM) 8 in experimental asthma.

King NE, Zimmermann N, Pope SM, Fulkerson PC, Nikolaidis NM, Mishra A, Witte DP, Rothenberg ME.

Am J Respir Cell Mol Biol. 2004 Sep;31(3):257-65. Epub 2004 Apr 15.


Negative regulation of eosinophil recruitment to the lung by the chemokine monokine induced by IFN-gamma (Mig, CXCL9).

Fulkerson PC, Zimmermann N, Brandt EB, Muntel EE, Doepker MP, Kavanaugh JL, Mishra A, Witte DP, Zhang H, Farber JM, Yang M, Foster PS, Rothenberg ME.

Proc Natl Acad Sci U S A. 2004 Feb 17;101(7):1987-92. Epub 2004 Feb 9.


Foxa2 regulates alveolarization and goblet cell hyperplasia.

Wan H, Kaestner KH, Ang SL, Ikegami M, Finkelman FD, Stahlman MT, Fulkerson PC, Rothenberg ME, Whitsett JA.

Development. 2004 Feb;131(4):953-64.


Transcript signatures in experimental asthma: identification of STAT6-dependent and -independent pathways.

Zimmermann N, Mishra A, King NE, Fulkerson PC, Doepker MP, Nikolaidis NM, Kindinger LE, Moulton EA, Aronow BJ, Rothenberg ME.

J Immunol. 2004 Feb 1;172(3):1815-24.


Role of TC21/R-Ras2 in enhanced migration of neurofibromin-deficient Schwann cells.

Huang Y, Rangwala F, Fulkerson PC, Ling B, Reed E, Cox AD, Kamholz J, Ratner N.

Oncogene. 2004 Jan 15;23(2):368-78.

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