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LOTUS domain protein MARF1 binds CCR4-NOT deadenylase complex to post-transcriptionally regulate gene expression in oocytes.

Zhu L, Kandasamy SK, Liao SE, Fukunaga R.

Nat Commun. 2018 Oct 2;9(1):4031. doi: 10.1038/s41467-018-06404-w.


Discriminating Formal Representations of Risk in Anterior Cingulate Cortex and Inferior Frontal Gyrus.

Fukunaga R, Purcell JR, Brown JW.

Front Neurosci. 2018 Aug 14;12:553. doi: 10.3389/fnins.2018.00553. eCollection 2018.


An RNA-binding protein Blanks plays important roles in defining small RNA and mRNA profiles in Drosophila testes.

Liao SE, Ai Y, Fukunaga R.

Heliyon. 2018 Jul 25;4(7):e00706. doi: 10.1016/j.heliyon.2018.e00706. eCollection 2018 Jul.


A simple antegrade perfusion method for isolating viable single cardiomyocytes from neonatal to aged mice.

Omatsu-Kanbe M, Yoshioka K, Fukunaga R, Sagawa H, Matsuura H.

Physiol Rep. 2018 May;6(9):e13688. doi: 10.14814/phy2.13688.


Allele-specific differences in transcriptome, miRNome, and mitochondrial function in two hypertrophic cardiomyopathy mouse models.

Vakrou S, Fukunaga R, Foster DB, Sorensen L, Liu Y, Guan Y, Woldemichael K, Pineda-Reyes R, Liu T, Tardiff JC, Leinwand LA, Tocchetti CG, Abraham TP, O'Rourke B, Aon MA, Abraham MR.

JCI Insight. 2018 Mar 22;3(6). pii: 94493. doi: 10.1172/jci.insight.94493. [Epub ahead of print]


Loquacious-PD removes phosphate inhibition of Dicer-2 processing of hairpin RNAs into siRNAs.

Fukunaga R.

Biochem Biophys Res Commun. 2018 Apr 15;498(4):1022-1027. doi: 10.1016/j.bbrc.2018.03.108. Epub 2018 Mar 16.


Dicer partner protein tunes the length of miRNAs using base-mismatch in the pre-miRNA stem.

Zhu L, Kandasamy SK, Fukunaga R.

Nucleic Acids Res. 2018 Apr 20;46(7):3726-3741. doi: 10.1093/nar/gky043.


Kinetic Analysis of Small Silencing RNA Production by Human and Drosophila Dicer Enzymes In Vitro.

Liao SE, Fukunaga R.

Methods Mol Biol. 2018;1680:101-121. doi: 10.1007/978-1-4939-7339-2_7.


Examining the reach of a brief alcohol intervention service in routine practice at a level 1 trauma center.

Turner BJ, McCann BS, Dunn CW, Darnell DA, Beam CR, Kleiber B, Nelson KM, Fukunaga R.

J Subst Abuse Treat. 2017 Aug;79:29-33. doi: 10.1016/j.jsat.2017.05.011. Epub 2017 May 20.


Disruption of white matter structural integrity and connectivity in posttraumatic stress disorder: A TBSS and tractography study.

Olson EA, Cui J, Fukunaga R, Nickerson LD, Rauch SL, Rosso IM.

Depress Anxiety. 2017 May;34(5):437-445. doi: 10.1002/da.22615. Epub 2017 Mar 15.


Internet-based cognitive behavior therapy for major depressive disorder: A randomized controlled trial.

Rosso IM, Killgore WD, Olson EA, Webb CA, Fukunaga R, Auerbach RP, Gogel H, Buchholz JL, Rauch SL.

Depress Anxiety. 2017 Mar;34(3):236-245. doi: 10.1002/da.22590. Epub 2016 Dec 23.


Phosphate-binding pocket in Dicer-2 PAZ domain for high-fidelity siRNA production.

Kandasamy SK, Fukunaga R.

Proc Natl Acad Sci U S A. 2016 Dec 6;113(49):14031-14036. Epub 2016 Nov 21.


Primary aortoduodenal fistula with a history of distal gastrectomy.

Inoue K, Fukunaga R, Matsubara Y, Aoyagi Y, Matsuda D, Kyuragi R, Morisaki K, Matsumoto T, Oki E, Maehara Y.

Acute Med Surg. 2016 Jun 9;4(1):105-108. doi: 10.1002/ams2.224. eCollection 2017 Jan.


Common miR-590 Variant rs6971711 Present Only in African Americans Reduces miR-590 Biogenesis.

Lin X, Steinberg S, Kandasamy SK, Afzal J, Mbiyangandu B, Liao SE, Guan Y, Corona-Villalobos CP, Matkovich SJ, Epstein N, Tripodi D, Huo Z, Cutting G, Abraham TP, Fukunaga R, Abraham MR.

PLoS One. 2016 May 19;11(5):e0156065. doi: 10.1371/journal.pone.0156065. eCollection 2016.


Raison d'etre of Tibial Artery Bypass for Intermittent Claudication in the Era of Endovascular Therapy.

Mii S, Tanaka K, Kyuragi R, Kuma S, Kodama A, Fukunaga R, Masaki I, Okazaki J, Eguchi D, Yamaoka T, Mori A, Guntani A, Okadome J.

Circ J. 2016 May 25;80(6):1460-9. doi: 10.1253/circj.CJ-16-0169. Epub 2016 May 17.


Long-Term Results of a Hybrid Revascularization Procedure for Peripheral Arterial Disease.

Okadome J, Matsumoto T, Aoyagi Y, Matsuda D, Tanaka S, Kawakubo E, Kyuragi R, Morisaki K, Homma K, Iwasa K, Ohmine T, Guntani A, Fukunaga R, Maehara Y.

Fukuoka Igaku Zasshi. 2015 Sep;106(9):254-61.


Comparisons of prevalence and related factors of depression in middle-aged adults between urban and rural populations in Japan.

Fujise N, Abe Y, Fukunaga R, Nakagawa Y, Nishi Y, Koyama A, Ikeda M.

J Affect Disord. 2016 Jan 15;190:772-776. doi: 10.1016/j.jad.2015.11.020. Epub 2015 Nov 17.


Reward salience and risk aversion underlie differential ACC activity in substance dependence.

Alexander WH, Fukunaga R, Finn P, Brown JW.

Neuroimage Clin. 2015 Mar 28;8:59-71. doi: 10.1016/j.nicl.2015.02.025. eCollection 2015.


Neural activation during risky decision-making in youth at high risk for substance use disorders.

Hulvershorn LA, Hummer TA, Fukunaga R, Leibenluft E, Finn P, Cyders MA, Anand A, Overhage L, Dir A, Brown J.

Psychiatry Res. 2015 Aug 30;233(2):102-11. doi: 10.1016/j.pscychresns.2015.05.007. Epub 2015 May 21.


Ultrasound-guided percutaneous thrombin injection for post-catheterization pseudoaneurysm.

Kuma S, Morisaki K, Kodama A, Guntani A, Fukunaga R, Soga Y, Shirai S, Ishida M, Okazaki J, Mii S.

Circ J. 2015;79(6):1277-81. doi: 10.1253/circj.CJ-14-1119. Epub 2015 Mar 20.


A SelB/EF-Tu/aIF2γ-like protein from Methanosarcina mazei in the GTP-bound form binds cysteinyl-tRNA(Cys.).

Yanagisawa T, Ishii R, Hikida Y, Fukunaga R, Sengoku T, Sekine S, Yokoyama S.

J Struct Funct Genomics. 2015 Mar;16(1):25-41. doi: 10.1007/s10969-015-9193-6. Epub 2015 Jan 25.


Two-stage translational control of dentate gyrus LTP consolidation is mediated by sustained BDNF-TrkB signaling to MNK.

Panja D, Kenney JW, D'Andrea L, Zalfa F, Vedeler A, Wibrand K, Fukunaga R, Bagni C, Proud CG, Bramham CR.

Cell Rep. 2014 Nov 20;9(4):1430-45. doi: 10.1016/j.celrep.2014.10.016. Epub 2014 Nov 6.


Thoracic endovascular aortic repair and coil embolization of the pulmonary artery for primary racemose hemangioma of the bronchial artery with a bronchial-pulmonary artery fistula.

Matsubara Y, Morisaki K, Matsuda D, Aoyagi Y, Tanaka S, Okadome J, Fukunaga R, Matsumoto T, Maehara Y.

Vascular. 2015 Aug;23(4):436-9. doi: 10.1177/1708538114551196. Epub 2014 Sep 22.


Regulatory effects of a Mnk2-eIF4E feedback loop during mTORC1 targeting of human medulloblastoma cells.

Eckerdt F, Beauchamp E, Bell J, Iqbal A, Su B, Fukunaga R, Lulla RR, Goldman S, Platanias LC.

Oncotarget. 2014 Sep 30;5(18):8442-51.


Mnk1 is a novel acinar cell-specific kinase required for exocrine pancreatic secretion and response to pancreatitis in mice.

Cendrowski J, Lobo VJ, Sendler M, Salas A, Kühn JP, Molero X, Fukunaga R, Mayerle J, Lerch MM, Real FX.

Gut. 2015 Jun;64(6):937-47. doi: 10.1136/gutjnl-2013-306068. Epub 2014 Jul 18.


Midterm outcomes of endovascular repair for abdominal aortic aneurysms with the on-label use compared with the off-label use of an endoprosthesis.

Matsumoto T, Tanaka S, Okadome J, Kyuragi R, Fukunaga R, Kawakubo E, Itoh H, Okazaki J, Shirabe K, Fukuda A, Maehara Y.

Surg Today. 2015 Jul;45(7):880-5. doi: 10.1007/s00595-014-0978-1. Epub 2014 Jul 18.


Thoracic stent graft with distal fenestration for the superior mesenteric artery for treatment of thoracic aortic aneurysm.

Fukunaga R, Matsumoto T, Aoyagi Y, Matsuda D, Tanaka S, Okadome J, Morisaki K, Maehara Y.

Ann Vasc Dis. 2014;7(2):152-5. doi: 10.3400/ Epub 2014 Mar 31.


Successful treatment of an abdominal aortic aneurysm with a severely angulated and large aortic neck using a modified Zenith.

Guntani A, Fukunaga R, Kuma S, Okazaki J, Nishihara Y, Aibe H, Okadome J, Morisaki K, Matsumoto T, Maehara Y.

Fukuoka Igaku Zasshi. 2014 Jan;105(1):16-21.


A universal small molecule, inorganic phosphate, restricts the substrate specificity of Dicer-2 in small RNA biogenesis.

Fukunaga R, Zamore PD.

Cell Cycle. 2014;13(11):1671-6. doi: 10.4161/cc.29066. Epub 2014 Apr 30.


Item non-response on self-reported depression screening questionnaire among community-dwelling elderly.

Koyama A, Fukunaga R, Abe Y, Nishi Y, Fujise N, Ikeda M.

J Affect Disord. 2014 Jun;162:30-3. doi: 10.1016/j.jad.2014.03.022. Epub 2014 Mar 27.


Thyroid antibodies are associated with stenotic lesions in the terminal portion of the internal carotid artery.

Tanaka M, Sakaguchi M, Yagita Y, Gon Y, Yoshikawa K, Takahashi T, Fukunaga R, Mochizuki H, Kitagawa K.

Eur J Neurol. 2014 Jun;21(6):867-73. doi: 10.1111/ene.12397. Epub 2014 Mar 6.


Inorganic phosphate blocks binding of pre-miRNA to Dicer-2 via its PAZ domain.

Fukunaga R, Colpan C, Han BW, Zamore PD.

EMBO J. 2014 Feb 18;33(4):371-84. doi: 10.1002/embj.201387176. Epub 2014 Jan 31.


Interplay between chromatin-modifying enzymes controls colon cancer progression through Wnt signaling.

Chevillard-Briet M, Quaranta M, Grézy A, Mattera L, Courilleau C, Philippe M, Mercier P, Corpet D, Lough J, Ueda T, Fukunaga R, Trouche D, Escaffit F.

Hum Mol Genet. 2014 Apr 15;23(8):2120-31. doi: 10.1093/hmg/ddt604. Epub 2013 Nov 28.



Fukunaga R, Fujise N, Ikeda M.

Nihon Rinsho. 2013 Oct;71(10):1798-803. Japanese.


Mnk1 and 2 are dispensable for T cell development and activation but important for the pathogenesis of experimental autoimmune encephalomyelitis.

Gorentla BK, Krishna S, Shin J, Inoue M, Shinohara ML, Grayson JM, Fukunaga R, Zhong XP.

J Immunol. 2013 Feb 1;190(3):1026-37. doi: 10.4049/jimmunol.1200026. Epub 2012 Dec 26.


Decisions during negatively-framed messages yield smaller risk-aversion-related brain activation in substance-dependent individuals.

Fukunaga R, Bogg T, Finn PR, Brown JW.

Psychol Addict Behav. 2013 Dec;27(4):1141-52. doi: 10.1037/a0030633. Epub 2012 Nov 12.


Dicer Partner Proteins Tune the Length of Mature miRNAs in Flies and Mammals.

Fukunaga R, Han BW, Hung JH, Xu J, Weng Z, Zamore PD.

Cell. 2012 Nov 9;151(4):912. doi: 10.1016/j.cell.2012.10.029. Epub 2012 Nov 8. No abstract available.


Sprouty proteins are negative regulators of interferon (IFN) signaling and IFN-inducible biological responses.

Sharma B, Joshi S, Sassano A, Majchrzak B, Kaur S, Aggarwal P, Nabet B, Bulic M, Stein BL, McMahon B, Baker DP, Fukunaga R, Altman JK, Licht JD, Fish EN, Platanias LC.

J Biol Chem. 2012 Dec 7;287(50):42352-60. doi: 10.1074/jbc.M112.400721. Epub 2012 Oct 16.


Dicer partner proteins tune the length of mature miRNAs in flies and mammals.

Fukunaga R, Han BW, Hung JH, Xu J, Weng Z, Zamore PD.

Cell. 2012 Oct 26;151(3):533-46. doi: 10.1016/j.cell.2012.09.027. Epub 2012 Oct 11. Erratum in: Cell. 2012 Nov 9;151(4):912. Cell. 2012 Nov 9;151(4):912.


Living alone is associated with depression among the elderly in a rural community in Japan.

Fukunaga R, Abe Y, Nakagawa Y, Koyama A, Fujise N, Ikeda M.

Psychogeriatrics. 2012 Sep;12(3):179-85. doi: 10.1111/j.1479-8301.2012.00402.x.


Prevalence of Sjögren's syndrome with dementia in a memory clinic.

Yoshikawa K, Hatate J, Toratani N, Sugiura S, Shimizu Y, Takahash T, Ito T, Fukunaga R.

J Neurol Sci. 2012 Nov 15;322(1-2):217-21. doi: 10.1016/j.jns.2012.07.060. Epub 2012 Aug 17.


Decision making in the Balloon Analogue Risk Task (BART): anterior cingulate cortex signals loss aversion but not the infrequency of risky choices.

Fukunaga R, Brown JW, Bogg T.

Cogn Affect Behav Neurosci. 2012 Sep;12(3):479-90. doi: 10.3758/s13415-012-0102-1. Erratum in: Cogn Affect Behav Neurosci. 2012 Dec;12(4):826.


MNK kinases facilitate c-myc IRES activity in rapamycin-treated multiple myeloma cells.

Shi Y, Frost P, Hoang B, Yang Y, Fukunaga R, Gera J, Lichtenstein A.

Oncogene. 2013 Jan 10;32(2):190-7. doi: 10.1038/onc.2012.43. Epub 2012 Feb 27.


Comparisons of the prevalence of and risk factors for elderly depression between urban and rural populations in Japan.

Abe Y, Fujise N, Fukunaga R, Nakagawa Y, Ikeda M.

Int Psychogeriatr. 2012 Aug;24(8):1235-41. doi: 10.1017/S1041610212000099. Epub 2012 Feb 20.


Clinical Results of Endovascular Abdominal Aortic Aneurysm Repair in Patients with Renal Insufficiency without Hemodialysis.

Guntani A, Okadome J, Kawakubo E, Kyuragi R, Iwasa K, Fukunaga R, Kuma S, Matsumoto T, Okazaki J, Maehara Y.

Ann Vasc Dis. 2012;5(2):166-71. doi: 10.3400/avd.oa.11.00094.


Cognitive control links alcohol use, trait disinhibition, and reduced cognitive capacity: Evidence for medial prefrontal cortex dysregulation during reward-seeking behavior.

Bogg T, Fukunaga R, Finn PR, Brown JW.

Drug Alcohol Depend. 2012 Apr 1;122(1-2):112-8. doi: 10.1016/j.drugalcdep.2011.09.018. Epub 2011 Oct 10.


Case reports of unexpected suicides in patients within six months after stroke.

Katayama M, Naritomi H, Oomura M, Nukata M, Yamamoto S, Araki K, Kato H, Kinoshita M, Ito T, Shimode A, Takenobu Y, Watanabe M, Fukunaga R, Taguchi A, Hazama A, Inglin M, Krieger DW.

Kobe J Med Sci. 2011 Feb 2;56(5):E184-94.


Lifestyle modification and prevention of type 2 diabetes in overweight Japanese with impaired fasting glucose levels: a randomized controlled trial.

Saito T, Watanabe M, Nishida J, Izumi T, Omura M, Takagi T, Fukunaga R, Bandai Y, Tajima N, Nakamura Y, Ito M; Zensharen Study for Prevention of Lifestyle Diseases Group.

Arch Intern Med. 2011 Aug 8;171(15):1352-60. doi: 10.1001/archinternmed.2011.275.


Delayed closure technique for a ruptured abdominal aortic aneurysm: report of three cases.

Morisaki K, Fukunaga R, Ito H, Maehara Y.

Surg Today. 2011 Jul;41(7):1003-6. doi: 10.1007/s00595-010-4385-y. Epub 2011 Jul 12.


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