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Items: 1 to 50 of 964

1.

FABP3 in the Anterior Cingulate Cortex Modulates the Methylation Status of the Glutamic Acid Decarboxylase67 Promoter Region.

Yamamoto Y, Kida H, Kagawa Y, Yasumoto Y, Miyazaki H, Islam A, Ogata M, Yanagawa Y, Mitsushima D, Fukunaga K, Owada Y.

J Neurosci. 2018 Oct 19. pii: 1285-18. doi: 10.1523/JNEUROSCI.1285-18.2018. [Epub ahead of print]

PMID:
30341178
2.

Deficiency of CRTH2, a Prostaglandin D2 Receptor, Aggravates Bleomycin-Induced Pulmonary Inflammation and Fibrosis.

Ueda S, Fukunaga K, Takihara T, Shiraishi Y, Oguma T, Shiomi T, Suzuki Y, Ishii M, Sayama K, Kagawa S, Hirai H, Nagata K, Nakamura M, Miyasho T, Betsuyaku T, Asano K.

Am J Respir Cell Mol Biol. 2018 Oct 16. doi: 10.1165/rcmb.2017-0397OC. [Epub ahead of print]

PMID:
30326727
3.

Aberrant Amygdala-Dependent Cued Fear Memory in Na+/Ca2+ Exchanger 1 Heterozygous Mice.

Moriguchi S, Kita S, Inagaki R, Yabuki Y, Sasaki Y, Ishikawa S, Sakagami H, Iwamoto T, Fukunaga K.

Mol Neurobiol. 2018 Oct 15. doi: 10.1007/s12035-018-1384-2. [Epub ahead of print]

PMID:
30324228
4.

[Neurological mechanism and therapeutic strategy for posttraumatic stress disorders].

Fukunaga K, Yabuki Y, Takahata I, Matsuo K.

Nihon Yakurigaku Zasshi. 2018;152(4):194-201. doi: 10.1254/fpj.152.194. Japanese.

PMID:
30298841
5.

Nintedanib prevented fibrosis progression and lung cancer growth in idiopathic pulmonary fibrosis.

Fukunaga K, Yokoe S, Kawashima S, Uchida Y, Nakagawa H, Nakano Y.

Respirol Case Rep. 2018 Sep 14;6(8):e00363. doi: 10.1002/rcr2.363. eCollection 2018 Nov.

6.

SA4503, A Potent Sigma-1 Receptor Ligand, Ameliorates Synaptic Abnormalities and Cognitive Dysfunction in a Mouse Model of ATR-X Syndrome.

Yamaguchi K, Shioda N, Yabuki Y, Zhang C, Han F, Fukunaga K.

Int J Mol Sci. 2018 Sep 18;19(9). pii: E2811. doi: 10.3390/ijms19092811.

7.

Concyclic CH-π arrays for single-axis rotations of a bowl in a tube.

Matsuno T, Fujita M, Fukunaga K, Sato S, Isobe H.

Nat Commun. 2018 Sep 17;9(1):3779. doi: 10.1038/s41467-018-06270-6.

8.

Author's reply: Atrial fibrillation and sleep apnea: A chicken and egg situation.

Kimura T, Kohno T, Fukunaga K, Yamasawa W, Fujisawa T, Fukuoka R, Nakajima K, Kashimura S, Kunitomi A, Katsumata Y, Nishiyama T, Nishiyama N, Aizawa Y, Fukuda K, Takatsuki S.

Int J Cardiol. 2018 Nov 1;270:187. doi: 10.1016/j.ijcard.2018.06.049. No abstract available.

PMID:
30219532
9.

A Case of Bilateral Adrenocortical Adenomas along with Virilization and Cushing's Syndrome.

Kobayashi T, Imachi H, Sato S, Ibata T, Fukunaga K, Yoshimoto T, Kikuchi F, Yonezaki K, Yamaji N, Lyu J, Dong T, Nagata H, Kadota K, Kushida Y, Haba R, Murao K.

Intern Med. 2018 Sep 12. doi: 10.2169/internalmedicine.0790-18. [Epub ahead of print]

10.

Selective peroxisome proliferator-activated receptor-α modulator K-877 regulates the expression of ATP-binding cassette transporter A1 in pancreatic beta cells.

Dong T, Lyu J, Imachi H, Kobayashi T, Fukunaga K, Sato S, Ibata T, Yoshimoto T, Yonezaki K, Iwama H, Zhang G, Murao K.

Eur J Pharmacol. 2018 Nov 5;838:78-84. doi: 10.1016/j.ejphar.2018.09.015. Epub 2018 Sep 7.

PMID:
30201376
11.

T-type calcium channel enhancer SAK3 produces anti-depressant-like effects by promoting adult hippocampal neurogenesis in olfactory bulbectomized mice.

Xu J, Yabuki Y, Yu M, Fukunaga K.

J Pharmacol Sci. 2018 Aug;137(4):333-341. doi: 10.1016/j.jphs.2018.07.006. Epub 2018 Jul 17.

12.

Effect of TNF-α on the expression of ABCA1 in pancreatic β-cells.

Sato S, Imachi H, Lyu J, Miyai Y, Fukunaga K, Dong T, Ibata T, Kobayashi T, Yoshimoto T, Kikuchi F, Yonezaki K, Yamaji N, Iwama H, Murao K.

J Mol Endocrinol. 2018 Oct 15;61(4):185-193. doi: 10.1530/JME-18-0167.

PMID:
30131353
13.

IGF1 suppresses cholesterol accumulation in the liver of growth hormone deficient mice via the activation of ABCA1.

Fukunaga K, Imachi H, Lyu J, Dong T, Sato S, Ibata T, Kobayashi T, Yoshimoto T, Yonezaki K, Matsunaga T, Murao K.

Am J Physiol Endocrinol Metab. 2018 Aug 21. doi: 10.1152/ajpendo.00134.2018. [Epub ahead of print]

PMID:
30130150
14.

Aberrant Amygdala-dependent Fear Memory in Corticosterone-treated Mice.

Inagaki R, Moriguchi S, Fukunaga K.

Neuroscience. 2018 Sep 15;388:448-459. doi: 10.1016/j.neuroscience.2018.08.004. Epub 2018 Aug 16.

PMID:
30118751
15.

Angiotensin II induces cholesterol accumulation and impairs insulin secretion by regulating ABCA1 in beta cells.

Lyu J, Imachi H, Fukunaga K, Sato S, Ibata T, Kobayashi T, Dong T, Yoshimoto T, Yonezaki K, Nagata H, Iwama H, Murao K.

J Lipid Res. 2018 Oct;59(10):1906-1915. doi: 10.1194/jlr.M085886. Epub 2018 Aug 14.

PMID:
30108153
16.

Inhibition of Nicotine Dependence by Curcuminoid Is Associated with Reduced Acetylcholinesterase Activity in the Mouse Brain.

Wilar G, Anggadiredja K, Shinoda Y, Fukunaga K.

Pharmacology. 2018;102(3-4):223-232. doi: 10.1159/000492154. Epub 2018 Aug 10.

PMID:
30099467
17.

Improving Efficacy and Safety of Agonistic Anti-CD40 Antibody Through Extracellular Matrix Affinity.

Ishihara J, Ishihara A, Potin L, Hosseinchi P, Fukunaga K, Damo M, Gajewski TF, Swartz MA, Hubbell JA.

Mol Cancer Ther. 2018 Aug 10. doi: 10.1158/1535-7163.MCT-18-0091. [Epub ahead of print]

PMID:
30097487
18.

GSTP1 rs1695 is associated with both hematological toxicity and prognosis of ovarian cancer treated with paclitaxel plus carboplatin combination chemotherapy: a comprehensive analysis using targeted resequencing of 100 pharmacogenes.

Yoshihama T, Fukunaga K, Hirasawa A, Nomura H, Akahane T, Kataoka F, Yamagami W, Aoki D, Mushiroda T.

Oncotarget. 2018 Jul 3;9(51):29789-29800. doi: 10.18632/oncotarget.25712. eCollection 2018 Jul 3.

19.

Effects of three infusion fluids with different sodium chloride contents on steady-state serum concentrations of bromide in dogs.

Fukunaga K, Matsumoto H, Wate M, Misawa K, Saito M, Matsuda H, Orito K.

J Vet Pharmacol Ther. 2018 Oct;41(5):684-690. doi: 10.1111/jvp.12680. Epub 2018 Jul 18.

PMID:
30020534
20.

Combination therapy of ipilimumab and nivolumab induced thyroid storm in a patient with Hashimoto's disease and diabetes mellitus: a case report.

Yonezaki K, Kobayashi T, Imachi H, Yoshimoto T, Kikuchi F, Fukunaga K, Sato S, Ibata T, Yamaji N, Lyu J, Dong T, Murao K.

J Med Case Rep. 2018 Jun 19;12(1):171. doi: 10.1186/s13256-018-1708-x.

21.

Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing.

Ishihara J, Ishihara A, Fukunaga K, Sasaki K, White MJV, Briquez PS, Hubbell JA.

Nat Commun. 2018 Jun 4;9(1):2163. doi: 10.1038/s41467-018-04525-w.

22.

Targeting G-quadruplex DNA as cognitive function therapy for ATR-X syndrome.

Shioda N, Yabuki Y, Yamaguchi K, Onozato M, Li Y, Kurosawa K, Tanabe H, Okamoto N, Era T, Sugiyama H, Wada T, Fukunaga K.

Nat Med. 2018 Jun;24(6):802-813. doi: 10.1038/s41591-018-0018-6. Epub 2018 May 21.

PMID:
29785027
23.

NAT2 ultra-slow acetylator and risk of anti-tuberculosis drug-induced liver injury: a genotype-based meta-analysis.

Suvichapanich S, Fukunaga K, Zahroh H, Mushiroda T, Mahasirimongkol S, Toyo-Oka L, Chaikledkaew U, Jittikoon J, Yuliwulandari R, Yanai H, Wattanapokayakit S, Tokunaga K.

Pharmacogenet Genomics. 2018 Jul;28(7):167-176. doi: 10.1097/FPC.0000000000000339.

PMID:
29781872
24.

Neuroprotective effects of protein tyrosine phosphatase 1B inhibitor on cerebral ischemia/reperfusion in mice.

Sun M, Izumi H, Shinoda Y, Fukunaga K.

Brain Res. 2018 Sep 1;1694:1-12. doi: 10.1016/j.brainres.2018.04.029. Epub 2018 Apr 26.

PMID:
29705606
25.

In-stent restenosis assessed by frequency-domain optical coherence tomography shows smooth coronary arterial healing process in second-generation drug-eluting stents.

Kajiya T, Yamaguchi H, Takaoka J, Fukunaga K, Arima R, Miyamura A, Ninomiya T, Atsuchi N, Atsuchi Y, Terashima M, Kaneda H, Ohishi M.

Singapore Med J. 2018 Apr 10. doi: 10.11622/smedj.2018038. [Epub ahead of print]

26.

Prevalence and clinical characteristics of obstructive- and central-dominant sleep apnea in candidates of catheter ablation for atrial fibrillation in Japan.

Kohno T, Kimura T, Fukunaga K, Yamasawa W, Fujisawa T, Fukuoka R, Nakajima K, Kashimura S, Kunitomi A, Katsumata Y, Nishiyama T, Nishiyama N, Aizawa Y, Fukuda K, Takatsuki S.

Int J Cardiol. 2018 Jun 1;260:99-102. doi: 10.1016/j.ijcard.2018.01.103.

PMID:
29622460
27.

Acute Treatment with T-Type Calcium Channel Enhancer SAK3 Reduces Cognitive Impairments Caused by Methimazole-Induced Hypothyroidism Via Activation of Cholinergic Signaling.

Husain N, Yabuki Y, Shinoda Y, Fukunaga K.

Pharmacology. 2018;101(5-6):309-321. doi: 10.1159/000488083. Epub 2018 Mar 29.

PMID:
29597200
28.

The Disease-modifying Drug Candidate, SAK3 Improves Cognitive Impairment and Inhibits Amyloid beta Deposition in App Knock-in Mice.

Izumi H, Shinoda Y, Saito T, Saido TC, Sato K, Yabuki Y, Matsumoto Y, Kanemitsu Y, Tomioka Y, Abolhassani N, Nakabeppu Y, Fukunaga K.

Neuroscience. 2018 May 1;377:87-97. doi: 10.1016/j.neuroscience.2018.02.031. Epub 2018 Mar 3.

PMID:
29510211
29.

Development of Necrotizing Myopathy Following Interstitial Lung Disease with Anti-signal Recognition Particle Antibody.

Kusumoto T, Okamori S, Masuzawa K, Asakura T, Nishina N, Chubachi S, Naoki K, Fukunaga K, Betsuyaku T.

Intern Med. 2018 Jul 15;57(14):2045-2049. doi: 10.2169/internalmedicine.0303-17. Epub 2018 Feb 28.

30.

[EOSINOPHILS AND ANTI-INFLAMMATORY LIPID MEDIATORS].

Fukunaga K.

Arerugi. 2018;67(1):28-30. doi: 10.15036/arerugi.67.28. Japanese. No abstract available.

PMID:
29459522
31.

Myt1l induced direct reprogramming of pericytes into cholinergic neurons.

Liang XG, Tan C, Wang CK, Tao RR, Huang YJ, Ma KF, Fukunaga K, Huang MZ, Han F.

CNS Neurosci Ther. 2018 Feb 17. doi: 10.1111/cns.12821. [Epub ahead of print]

PMID:
29453933
32.

Intermittent Exposure to Cigarette Smoke Increases Lung Tumors and the Severity of Emphysema More than Continuous Exposure.

Kameyama N, Chubachi S, Hegab AE, Yasuda H, Kagawa S, Tsutsumi A, Fukunaga K, Shimoda M, Kanai Y, Soejima K, Betsuyaku T.

Am J Respir Cell Mol Biol. 2018 Aug;59(2):179-188. doi: 10.1165/rcmb.2017-0375OC.

PMID:
29443539
33.

Journal of Artificial Organs 2017: the year in review : Journal of Artificial Organs Editorial Committee.

Sawa Y, Matsumiya G, Matsuda K, Tatsumi E, Abe T, Fukunaga K, Ichiba S, Kishida A, Kokubo K, Masuzawa T, Myoui A, Nishimura M, Nishimura T, Nishinaka T, Okamoto E, Tokunaga S, Tomo T, Tsukiya T, Yagi Y, Yamaoka T.

J Artif Organs. 2018 Mar;21(1):1-7. doi: 10.1007/s10047-018-1018-5. Epub 2018 Feb 9. Review. No abstract available.

PMID:
29426998
34.

Ouabagenin is a naturally occurring LXR ligand without causing hepatic steatosis as a side effect.

Tamura S, Okada M, Kato S, Shinoda Y, Shioda N, Fukunaga K, Ui-Tei K, Ueda M.

Sci Rep. 2018 Feb 2;8(1):2305. doi: 10.1038/s41598-018-20663-z.

35.

Thyroid stimulating hormone stimulates the expression of glucose transporter 2 via its receptor in pancreatic β cell line, INS-1 cells.

Lyu J, Imachi H, Yoshimoto T, Fukunaga K, Sato S, Ibata T, Kobayashi T, Dong T, Yonezaki K, Yamaji N, Kikuchi F, Iwama H, Ishikawa R, Haba R, Sugiyama Y, Zhang H, Murao K.

Sci Rep. 2018 Jan 31;8(1):1986. doi: 10.1038/s41598-018-20449-3.

36.

Reduced expression of Na+/Ca2+ exchangers is associated with cognitive deficits seen in Alzheimer's disease model mice.

Moriguchi S, Kita S, Fukaya M, Osanai M, Inagaki R, Sasaki Y, Izumi H, Horie K, Takeda J, Saito T, Sakagami H, Saido TC, Iwamoto T, Fukunaga K.

Neuropharmacology. 2018 Mar 15;131:291-303. doi: 10.1016/j.neuropharm.2017.12.037. Epub 2017 Dec 22.

PMID:
29274751
37.

Physiological and Pathological Roles of CaMKII-PP1 Signaling in the Brain.

Shioda N, Fukunaga K.

Int J Mol Sci. 2017 Dec 22;19(1). pii: E20. doi: 10.3390/ijms19010020. Review.

38.

Construction of a system using a deep learning algorithm to count cell numbers in nanoliter wells for viable single-cell experiments.

Kamatani T, Fukunaga K, Miyata K, Shirasaki Y, Tanaka J, Baba R, Matsusaka M, Kamatani N, Moro K, Betsuyaku T, Uemura S.

Sci Rep. 2017 Dec 4;7(1):16831. doi: 10.1038/s41598-017-17012-x.

39.

Combination of NAD+ and NADPH Offers Greater Neuroprotection in Ischemic Stroke Models by Relieving Metabolic Stress.

Huang Q, Sun M, Li M, Zhang D, Han F, Wu JC, Fukunaga K, Chen Z, Qin ZH.

Mol Neurobiol. 2018 Jul;55(7):6063-6075. doi: 10.1007/s12035-017-0809-7. Epub 2017 Nov 21.

PMID:
29164394
40.

[Memantine improves cognitive function via KATP channel inhibition].

Moriguchi S, Fukunaga K.

Nihon Yakurigaku Zasshi. 2017;150(5):228-233. doi: 10.1254/fpj.150.228. Japanese. No abstract available.

PMID:
29118285
41.

Matrix-binding checkpoint immunotherapies enhance antitumor efficacy and reduce adverse events.

Ishihara J, Fukunaga K, Ishihara A, Larsson HM, Potin L, Hosseinchi P, Galliverti G, Swartz MA, Hubbell JA.

Sci Transl Med. 2017 Nov 8;9(415). pii: eaan0401. doi: 10.1126/scitranslmed.aan0401.

PMID:
29118259
42.

A H2O2-Responsive Theranostic Probe for Endothelial Injury Imaging and Protection.

Wang CK, Cheng J, Liang XG, Tan C, Jiang Q, Hu YZ, Lu YM, Fukunaga K, Han F, Li X.

Theranostics. 2017 Aug 23;7(15):3803-3813. doi: 10.7150/thno.21068. eCollection 2017.

43.

Association between severity of obstructive sleep apnea and glycated hemoglobin level in Japanese individuals with and without diabetes.

Kurosawa H, Saisho Y, Fukunaga K, Haraguchi M, Yamasawa W, Kurihara I, Betsuyaku T, Itoh H.

Endocr J. 2018 Jan 30;65(1):121-127. doi: 10.1507/endocrj.EJ17-0356. Epub 2017 Sep 20.

44.

Antisense RNA transcripts in the blood may be novel diagnostic markers for colorectal cancer.

Kurokawa T, Kohno K, Nagai K, Chiba M, Pak S, Murata S, Fukunaga K, Yasue H, Ohkohchi N.

Oncol Lett. 2017 Sep;14(3):3487-3493. doi: 10.3892/ol.2017.6572. Epub 2017 Jul 15.

45.

An exception among diatoms: unique organization of genes involved in isoprenoid biosynthesis in Rhizosolenia setigera CCMP 1694.

Ferriols VMEN, Yaginuma-Suzuki R, Fukunaga K, Kadono T, Adachi M, Matsunaga S, Okada S.

Plant J. 2017 Dec;92(5):822-833. doi: 10.1111/tpj.13719. Epub 2017 Nov 9.

PMID:
28921701
46.

12-OH-17,18-Epoxyeicosatetraenoic acid alleviates eosinophilic airway inflammation in murine lungs.

Mochimaru T, Fukunaga K, Miyata J, Matsusaka M, Masaki K, Kabata H, Ueda S, Suzuki Y, Goto T, Urabe D, Inoue M, Isobe Y, Arita M, Betsuyaku T.

Allergy. 2018 Feb;73(2):369-378. doi: 10.1111/all.13297. Epub 2017 Sep 25.

PMID:
28857178
47.

Subphenotypes of type 2 severe asthma in adults.

Matsusaka M, Fukunaga K, Kabata H, Izuhara K, Asano K, Betsuyaku T.

J Allergy Clin Immunol Pract. 2018 Jan - Feb;6(1):274-276.e2. doi: 10.1016/j.jaip.2017.06.015. Epub 2017 Aug 9. No abstract available.

PMID:
28803182
48.

Characteristics of severe asthma with fungal sensitization.

Masaki K, Fukunaga K, Matsusaka M, Kabata H, Tanosaki T, Mochimaru T, Kamatani T, Ohtsuka K, Baba R, Ueda S, Suzuki Y, Sakamaki F, Oyamada Y, Inoue T, Oguma T, Sayama K, Koh H, Nakamura M, Umeda A, Kamei K, Izuhara K, Asano K, Betsuyaku T.

Ann Allergy Asthma Immunol. 2017 Sep;119(3):253-257. doi: 10.1016/j.anai.2017.07.008. Epub 2017 Aug 8.

PMID:
28801088
49.

Melatonin ameliorates hypoglycemic stress-induced brain endothelial tight junction injury by inhibiting protein nitration of TP53-induced glycolysis and apoptosis regulator.

Wang CK, Ahmed MM, Jiang Q, Lu NN, Tan C, Gao YP, Mahmood Q, Chen DY, Fukunaga K, Li M, Chen Z, Wilcox CS, Lu YM, Qin ZH, Han F.

J Pineal Res. 2017 Nov;63(4). doi: 10.1111/jpi.12440. Epub 2017 Sep 6.

50.

D816 mutation of the KIT gene in core binding factor acute myeloid leukemia is associated with poorer prognosis than other KIT gene mutations.

Yui S, Kurosawa S, Yamaguchi H, Kanamori H, Ueki T, Uoshima N, Mizuno I, Shono K, Usuki K, Chiba S, Nakamura Y, Yanada M, Kanda J, Tajika K, Gomi S, Fukunaga K, Wakita S, Ryotokuji T, Fukuda T, Inokuchi K.

Ann Hematol. 2017 Oct;96(10):1641-1652. doi: 10.1007/s00277-017-3074-y. Epub 2017 Jul 31.

PMID:
28762080

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