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Items: 1 to 50 of 944

1.

Combination therapy of ipilimumab and nivolumab induced thyroid storm in a patient with Hashimoto's disease and diabetes mellitus: a case report.

Yonezaki K, Kobayashi T, Imachi H, Yoshimoto T, Kikuchi F, Fukunaga K, Sato S, Ibata T, Yamaji N, Lyu J, Dong T, Murao K.

J Med Case Rep. 2018 Jun 19;12(1):171. doi: 10.1186/s13256-018-1708-x.

2.

Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing.

Ishihara J, Ishihara A, Fukunaga K, Sasaki K, White MJV, Briquez PS, Hubbell JA.

Nat Commun. 2018 Jun 4;9(1):2163. doi: 10.1038/s41467-018-04525-w.

3.

Targeting G-quadruplex DNA as cognitive function therapy for ATR-X syndrome.

Shioda N, Yabuki Y, Yamaguchi K, Onozato M, Li Y, Kurosawa K, Tanabe H, Okamoto N, Era T, Sugiyama H, Wada T, Fukunaga K.

Nat Med. 2018 Jun;24(6):802-813. doi: 10.1038/s41591-018-0018-6. Epub 2018 May 21.

PMID:
29785027
4.

NAT2 ultra-slow acetylator and risk of anti-tuberculosis drug-induced liver injury: a genotype-based meta-analysis.

Suvichapanich S, Fukunaga K, Zahroh H, Mushiroda T, Mahasirimongkol S, Toyo-Oka L, Chaikledkaew U, Jittikoon J, Yuliwulandari R, Yanai H, Wattanapokayakit S, Tokunaga K.

Pharmacogenet Genomics. 2018 Jul;28(7):167-176. doi: 10.1097/FPC.0000000000000339.

PMID:
29781872
5.

Neuroprotective effects of protein tyrosine phosphatase 1B inhibitor on cerebral ischemia/reperfusion in mice.

Sun M, Izumi H, Shinoda Y, Fukunaga K.

Brain Res. 2018 Sep 1;1694:1-12. doi: 10.1016/j.brainres.2018.04.029. Epub 2018 Apr 26.

PMID:
29705606
6.

In-stent restenosis assessed by frequency-domain optical coherence tomography shows smooth coronary arterial healing process in second-generation drug-eluting stents.

Kajiya T, Yamaguchi H, Takaoka J, Fukunaga K, Arima R, Miyamura A, Ninomiya T, Atsuchi N, Atsuchi Y, Terashima M, Kaneda H, Ohishi M.

Singapore Med J. 2018 Apr 10. doi: 10.11622/smedj.2018038. [Epub ahead of print]

7.

Prevalence and clinical characteristics of obstructive- and central-dominant sleep apnea in candidates of catheter ablation for atrial fibrillation in Japan.

Kohno T, Kimura T, Fukunaga K, Yamasawa W, Fujisawa T, Fukuoka R, Nakajima K, Kashimura S, Kunitomi A, Katsumata Y, Nishiyama T, Nishiyama N, Aizawa Y, Fukuda K, Takatsuki S.

Int J Cardiol. 2018 Jun 1;260:99-102. doi: 10.1016/j.ijcard.2018.01.103.

PMID:
29622460
8.

Acute Treatment with T-Type Calcium Channel Enhancer SAK3 Reduces Cognitive Impairments Caused by Methimazole-Induced Hypothyroidism Via Activation of Cholinergic Signaling.

Husain N, Yabuki Y, Shinoda Y, Fukunaga K.

Pharmacology. 2018;101(5-6):309-321. doi: 10.1159/000488083. Epub 2018 Mar 29.

PMID:
29597200
9.

The Disease-modifying Drug Candidate, SAK3 Improves Cognitive Impairment and Inhibits Amyloid beta Deposition in App Knock-in Mice.

Izumi H, Shinoda Y, Saito T, Saido TC, Sato K, Yabuki Y, Matsumoto Y, Kanemitsu Y, Tomioka Y, Abolhassani N, Nakabeppu Y, Fukunaga K.

Neuroscience. 2018 May 1;377:87-97. doi: 10.1016/j.neuroscience.2018.02.031. Epub 2018 Mar 3.

PMID:
29510211
10.

Development of Necrotizing Myopathy Following Interstitial Lung Disease with Anti-signal Recognition Particle Antibody.

Kusumoto T, Okamori S, Masuzawa K, Asakura T, Nishina N, Chubachi S, Naoki K, Fukunaga K, Betsuyaku T.

Intern Med. 2018 Feb 28. doi: 10.2169/internalmedicine.0303-17. [Epub ahead of print]

11.

[EOSINOPHILS AND ANTI-INFLAMMATORY LIPID MEDIATORS].

Fukunaga K.

Arerugi. 2018;67(1):28-30. doi: 10.15036/arerugi.67.28. Japanese. No abstract available.

PMID:
29459522
12.

Myt1l induced direct reprogramming of pericytes into cholinergic neurons.

Liang XG, Tan C, Wang CK, Tao RR, Huang YJ, Ma KF, Fukunaga K, Huang MZ, Han F.

CNS Neurosci Ther. 2018 Feb 17. doi: 10.1111/cns.12821. [Epub ahead of print]

PMID:
29453933
13.

Intermittent Exposure to Cigarette Smoke Increases Lung Tumors and the Severity of Emphysema More Than Continuous Exposure.

Kameyama N, Chubachi S, Hegab AE, Yasuda H, Kagawa S, Tsutsumi A, Fukunaga K, Shimoda M, Kanai Y, Soejima K, Betsuyaku T.

Am J Respir Cell Mol Biol. 2018 Feb 14. doi: 10.1165/rcmb.2017-0375OC. [Epub ahead of print]

PMID:
29443539
14.

Journal of Artificial Organs 2017: the year in review : Journal of Artificial Organs Editorial Committee.

Sawa Y, Matsumiya G, Matsuda K, Tatsumi E, Abe T, Fukunaga K, Ichiba S, Kishida A, Kokubo K, Masuzawa T, Myoui A, Nishimura M, Nishimura T, Nishinaka T, Okamoto E, Tokunaga S, Tomo T, Tsukiya T, Yagi Y, Yamaoka T.

J Artif Organs. 2018 Mar;21(1):1-7. doi: 10.1007/s10047-018-1018-5. Epub 2018 Feb 9. Review. No abstract available.

PMID:
29426998
15.

Ouabagenin is a naturally occurring LXR ligand without causing hepatic steatosis as a side effect.

Tamura S, Okada M, Kato S, Shinoda Y, Shioda N, Fukunaga K, Ui-Tei K, Ueda M.

Sci Rep. 2018 Feb 2;8(1):2305. doi: 10.1038/s41598-018-20663-z.

16.

Thyroid stimulating hormone stimulates the expression of glucose transporter 2 via its receptor in pancreatic β cell line, INS-1 cells.

Lyu J, Imachi H, Yoshimoto T, Fukunaga K, Sato S, Ibata T, Kobayashi T, Dong T, Yonezaki K, Yamaji N, Kikuchi F, Iwama H, Ishikawa R, Haba R, Sugiyama Y, Zhang H, Murao K.

Sci Rep. 2018 Jan 31;8(1):1986. doi: 10.1038/s41598-018-20449-3.

17.

Reduced expression of Na+/Ca2+ exchangers is associated with cognitive deficits seen in Alzheimer's disease model mice.

Moriguchi S, Kita S, Fukaya M, Osanai M, Inagaki R, Sasaki Y, Izumi H, Horie K, Takeda J, Saito T, Sakagami H, Saido TC, Iwamoto T, Fukunaga K.

Neuropharmacology. 2018 Mar 15;131:291-303. doi: 10.1016/j.neuropharm.2017.12.037. Epub 2017 Dec 22.

PMID:
29274751
18.

Physiological and Pathological Roles of CaMKII-PP1 Signaling in the Brain.

Shioda N, Fukunaga K.

Int J Mol Sci. 2017 Dec 22;19(1). pii: E20. doi: 10.3390/ijms19010020. Review.

19.

Construction of a system using a deep learning algorithm to count cell numbers in nanoliter wells for viable single-cell experiments.

Kamatani T, Fukunaga K, Miyata K, Shirasaki Y, Tanaka J, Baba R, Matsusaka M, Kamatani N, Moro K, Betsuyaku T, Uemura S.

Sci Rep. 2017 Dec 4;7(1):16831. doi: 10.1038/s41598-017-17012-x.

20.

Combination of NAD+ and NADPH Offers Greater Neuroprotection in Ischemic Stroke Models by Relieving Metabolic Stress.

Huang Q, Sun M, Li M, Zhang D, Han F, Wu JC, Fukunaga K, Chen Z, Qin ZH.

Mol Neurobiol. 2018 Jul;55(7):6063-6075. doi: 10.1007/s12035-017-0809-7. Epub 2017 Nov 21.

PMID:
29164394
21.

[Memantine improves cognitive function via KATP channel inhibition].

Moriguchi S, Fukunaga K.

Nihon Yakurigaku Zasshi. 2017;150(5):228-233. doi: 10.1254/fpj.150.228. Japanese. No abstract available.

PMID:
29118285
22.

Matrix-binding checkpoint immunotherapies enhance antitumor efficacy and reduce adverse events.

Ishihara J, Fukunaga K, Ishihara A, Larsson HM, Potin L, Hosseinchi P, Galliverti G, Swartz MA, Hubbell JA.

Sci Transl Med. 2017 Nov 8;9(415). pii: eaan0401. doi: 10.1126/scitranslmed.aan0401.

PMID:
29118259
23.

A H2O2-Responsive Theranostic Probe for Endothelial Injury Imaging and Protection.

Wang CK, Cheng J, Liang XG, Tan C, Jiang Q, Hu YZ, Lu YM, Fukunaga K, Han F, Li X.

Theranostics. 2017 Aug 23;7(15):3803-3813. doi: 10.7150/thno.21068. eCollection 2017.

24.

Association between severity of obstructive sleep apnea and glycated hemoglobin level in Japanese individuals with and without diabetes.

Kurosawa H, Saisho Y, Fukunaga K, Haraguchi M, Yamasawa W, Kurihara I, Betsuyaku T, Itoh H.

Endocr J. 2018 Jan 30;65(1):121-127. doi: 10.1507/endocrj.EJ17-0356. Epub 2017 Sep 20.

25.

Antisense RNA transcripts in the blood may be novel diagnostic markers for colorectal cancer.

Kurokawa T, Kohno K, Nagai K, Chiba M, Pak S, Murata S, Fukunaga K, Yasue H, Ohkohchi N.

Oncol Lett. 2017 Sep;14(3):3487-3493. doi: 10.3892/ol.2017.6572. Epub 2017 Jul 15.

26.

An exception among diatoms: unique organization of genes involved in isoprenoid biosynthesis in Rhizosolenia setigera CCMP 1694.

Ferriols VMEN, Yaginuma-Suzuki R, Fukunaga K, Kadono T, Adachi M, Matsunaga S, Okada S.

Plant J. 2017 Dec;92(5):822-833. doi: 10.1111/tpj.13719. Epub 2017 Nov 9.

PMID:
28921701
27.

12-OH-17,18-Epoxyeicosatetraenoic acid alleviates eosinophilic airway inflammation in murine lungs.

Mochimaru T, Fukunaga K, Miyata J, Matsusaka M, Masaki K, Kabata H, Ueda S, Suzuki Y, Goto T, Urabe D, Inoue M, Isobe Y, Arita M, Betsuyaku T.

Allergy. 2018 Feb;73(2):369-378. doi: 10.1111/all.13297. Epub 2017 Sep 25.

PMID:
28857178
28.

Subphenotypes of type 2 severe asthma in adults.

Matsusaka M, Fukunaga K, Kabata H, Izuhara K, Asano K, Betsuyaku T.

J Allergy Clin Immunol Pract. 2018 Jan - Feb;6(1):274-276.e2. doi: 10.1016/j.jaip.2017.06.015. Epub 2017 Aug 9. No abstract available.

PMID:
28803182
29.

Characteristics of severe asthma with fungal sensitization.

Masaki K, Fukunaga K, Matsusaka M, Kabata H, Tanosaki T, Mochimaru T, Kamatani T, Ohtsuka K, Baba R, Ueda S, Suzuki Y, Sakamaki F, Oyamada Y, Inoue T, Oguma T, Sayama K, Koh H, Nakamura M, Umeda A, Kamei K, Izuhara K, Asano K, Betsuyaku T.

Ann Allergy Asthma Immunol. 2017 Sep;119(3):253-257. doi: 10.1016/j.anai.2017.07.008. Epub 2017 Aug 8.

PMID:
28801088
30.

Melatonin ameliorates hypoglycemic stress-induced brain endothelial tight junction injury by inhibiting protein nitration of TP53-induced glycolysis and apoptosis regulator.

Wang CK, Ahmed MM, Jiang Q, Lu NN, Tan C, Gao YP, Mahmood Q, Chen DY, Fukunaga K, Li M, Chen Z, Wilcox CS, Lu YM, Qin ZH, Han F.

J Pineal Res. 2017 Nov;63(4). doi: 10.1111/jpi.12440. Epub 2017 Sep 6.

31.

D816 mutation of the KIT gene in core binding factor acute myeloid leukemia is associated with poorer prognosis than other KIT gene mutations.

Yui S, Kurosawa S, Yamaguchi H, Kanamori H, Ueki T, Uoshima N, Mizuno I, Shono K, Usuki K, Chiba S, Nakamura Y, Yanada M, Kanda J, Tajika K, Gomi S, Fukunaga K, Wakita S, Ryotokuji T, Fukuda T, Inokuchi K.

Ann Hematol. 2017 Oct;96(10):1641-1652. doi: 10.1007/s00277-017-3074-y. Epub 2017 Jul 31.

PMID:
28762080
32.

Correction for Fukunaga et al., "Activation of Protein Kinase Tel1 through Recognition of Protein-Bound DNA Ends".

Fukunaga K, Kwon Y, Sung P, Sugimoto K.

Mol Cell Biol. 2017 Jul 28;37(16). pii: e00263-17. doi: 10.1128/MCB.00263-17. Print 2017 Aug 15. No abstract available.

33.

Discovery of novel 2-(3-phenylpiperazin-1-yl)-pyrimidin-4-ones as glycogen synthase kinase-3β inhibitors.

Usui Y, Uehara F, Hiki S, Watanabe K, Tanaka H, Shouda A, Yokoshima S, Aritomo K, Adachi T, Fukunaga K, Sunada S, Nabeno M, Saito KI, Eguchi JI, Yamagami K, Asano S, Tanaka S, Yuki S, Yoshii N, Fujimura M, Horikawa T.

Bioorg Med Chem Lett. 2017 Aug 15;27(16):3726-3732. doi: 10.1016/j.bmcl.2017.06.078. Epub 2017 Jul 5.

PMID:
28712708
34.

Discovery of novel 2-(4-aryl-2-methylpiperazin-1-yl)-pyrimidin-4-ones as glycogen synthase kinase-3β inhibitors.

Kohara T, Nakayama K, Watanabe K, Kusaka SI, Sakai D, Tanaka H, Fukunaga K, Sunada S, Nabeno M, Saito KI, Eguchi JI, Mori A, Tanaka S, Bessho T, Takiguchi-Hayashi K, Horikawa T.

Bioorg Med Chem Lett. 2017 Aug 15;27(16):3733-3738. doi: 10.1016/j.bmcl.2017.06.077. Epub 2017 Jul 5.

PMID:
28712706
35.

Differential Effects of Cod Proteins and Tuna Proteins on Serum and Liver Lipid Profiles in Rats Fed Non-Cholesterol- and Cholesterol-Containing Diets.

Hosomi R, Maeda H, Ikeda Y, Toda Y, Yoshida M, Fukunaga K.

Prev Nutr Food Sci. 2017 Jun;22(2):90-99. doi: 10.3746/pnf.2017.22.2.90. Epub 2017 Jun 30.

36.

Amlexanox Downregulates S100A6 to Sensitize KMT2A/AFF1-Positive Acute Lymphoblastic Leukemia to TNFα Treatment.

Tamai H, Yamaguchi H, Miyake K, Takatori M, Kitano T, Yamanaka S, Yui S, Fukunaga K, Nakayama K, Inokuchi K.

Cancer Res. 2017 Aug 15;77(16):4426-4433. doi: 10.1158/0008-5472.CAN-16-2974. Epub 2017 Jun 23.

PMID:
28646023
37.

Cholinergic Grb2-Associated-Binding Protein 1 Regulates Cognitive Function.

Lu NN, Tan C, Sun NH, Shao LX, Liu XX, Gao YP, Tao RR, Jiang Q, Wang CK, Huang JY, Zhao K, Wang GF, Liu ZR, Fukunaga K, Lu YM, Han F.

Cereb Cortex. 2018 Jul 1;28(7):2391-2404. doi: 10.1093/cercor/bhx141.

PMID:
28591834
38.

The alpha-lipoic acid derivative DHLHZn: a new therapeutic agent for acute lung injury in vivo.

Shoji Y, Takeuchi H, Fukuda K, Fukunaga K, Nakamura R, Takahashi T, Wada N, Kawakubo H, Miyasho T, Hiratsuka T, Inomata M, Betsuyaku T, Kitagawa Y.

Inflamm Res. 2017 Sep;66(9):803-811. doi: 10.1007/s00011-017-1059-x. Epub 2017 Jun 1.

PMID:
28573312
39.

Reduced CaM Kinase II and CaM Kinase IV Activities Underlie Cognitive Deficits in NCKX2 Heterozygous Mice.

Moriguchi S, Kita S, Yabuki Y, Inagaki R, Izumi H, Sasaki Y, Tagashira H, Horie K, Takeda J, Iwamoto T, Fukunaga K.

Mol Neurobiol. 2018 May;55(5):3889-3900. doi: 10.1007/s12035-017-0596-1. Epub 2017 May 25.

PMID:
28547530
40.

Allergic bronchopulmonary aspergillosis in Japan: A nationwide survey.

Oguma T, Taniguchi M, Shimoda T, Kamei K, Matsuse H, Hebisawa A, Takayanagi N, Konno S, Fukunaga K, Harada K, Tanaka J, Tomomatsu K, Asano K.

Allergol Int. 2018 Jan;67(1):79-84. doi: 10.1016/j.alit.2017.04.011. Epub 2017 May 23.

41.

Ramelteon Improves Post-traumatic Stress Disorder-Like Behaviors Exhibited by Fatty Acid-Binding Protein 3 Null Mice.

Yabuki Y, Takahata I, Matsuo K, Owada Y, Fukunaga K.

Mol Neurobiol. 2018 Apr;55(4):3577-3591. doi: 10.1007/s12035-017-0587-2. Epub 2017 May 17.

PMID:
28516430
42.

Effects of oolonghomobisflavan A on oxidation of low-density lipoprotein.

Sukhbold E, Sekimoto S, Watanabe E, Yamazaki A, Yang L, Takasugi M, Yamada K, Hosomi R, Fukunaga K, Arai H.

Biosci Biotechnol Biochem. 2017 Aug;81(8):1569-1575. doi: 10.1080/09168451.2017.1314758. Epub 2017 May 2.

PMID:
28463548
43.

The T-type calcium channel enhancer SAK3 inhibits neuronal death following transient brain ischemia via nicotinic acetylcholine receptor stimulation.

Yabuki Y, Jing X, Fukunaga K.

Neurochem Int. 2017 Sep;108:272-281. doi: 10.1016/j.neuint.2017.04.015. Epub 2017 Apr 27.

PMID:
28457878
44.

Dietary Tuna Dark Muscle Protein Attenuates Hepatic Steatosis and Increases Serum High-Density Lipoprotein Cholesterol in Obese Type-2 Diabetic/Obese KK-Ay Mice.

Maeda H, Hosomi R, Fukuda M, Ikeda Y, Yoshida M, Fukunaga K.

J Food Sci. 2017 May;82(5):1231-1238. doi: 10.1111/1750-3841.13711. Epub 2017 Apr 19.

PMID:
28422289
45.

trans-Fatty acids promote proinflammatory signaling and cell death by stimulating the apoptosis signal-regulating kinase 1 (ASK1)-p38 pathway.

Hirata Y, Takahashi M, Kudoh Y, Kano K, Kawana H, Makide K, Shinoda Y, Yabuki Y, Fukunaga K, Aoki J, Noguchi T, Matsuzawa A.

J Biol Chem. 2017 May 19;292(20):8174-8185. doi: 10.1074/jbc.M116.771519. Epub 2017 Mar 29.

46.

Combined l-citrulline and glutathione administration prevents neuronal cell death following transient brain ischemia.

Matsuo K, Yabuki Y, Fukunaga K.

Brain Res. 2017 May 15;1663:123-131. doi: 10.1016/j.brainres.2017.03.014. Epub 2017 Mar 14.

PMID:
28315310
47.

Stimulation of the Sigma-1 Receptor and the Effects on Neurogenesis and Depressive Behaviors in Mice.

Fukunaga K, Moriguchi S.

Adv Exp Med Biol. 2017;964:201-211. doi: 10.1007/978-3-319-50174-1_14. Review.

PMID:
28315273
48.

Novel spiroimidazopyridine derivative SAK3 improves methimazole-induced cognitive deficits in mice.

Noreen H, Yabuki Y, Fukunaga K.

Neurochem Int. 2017 Sep;108:91-99. doi: 10.1016/j.neuint.2017.03.001. Epub 2017 Mar 7.

PMID:
28279752
49.

The Effect of Three-Dimensional Preoperative Simulation on Liver Surgery.

Nakayama K, Oshiro Y, Miyamoto R, Kohno K, Fukunaga K, Ohkohchi N.

World J Surg. 2017 Jul;41(7):1840-1847. doi: 10.1007/s00268-017-3933-7.

50.

Obstructive sleep apnea syndrome should be considered as a cause of nocturia in younger patients without other voiding symptoms.

Maeda T, Fukunaga K, Nagata H, Haraguchi M, Kikuchi E, Miyajima A, Yamasawa W, Shirahama R, Narita M, Betsuyaku T, Asano K, Oya M.

Can Urol Assoc J. 2016 Jul-Aug;10(7-8):E241-E245. doi: 10.5489/cuaj.3508. Epub 2016 Jul 12.

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