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Items: 43


Application of Recombinase-Based In Vivo Expression Technology to Bifidobacterium longum subsp. longum for Identification of Genes Induced in the Gastrointestinal Tract of Mice.

Koguchi H, Ishigami N, Sakanaka M, Yoshida K, Hiratou S, Shimada M, Fukiya S, Sonoyama K, Yokota A.

Microorganisms. 2020 Mar 13;8(3). pii: E410. doi: 10.3390/microorganisms8030410.


Untargeted lipidomic analysis of plasma from high fat diet-induced obese rats using UHPLC- linear trap quadrupole -Orbitrap MS.

Gowda SGB, Gao ZJ, Chen Z, Abe T, Hori S, Fukiya S, Ishizuka S, Yokota A, Chiba H, Hui SP.

Anal Sci. 2020 Jan 17. doi: 10.2116/analsci.19P442. [Epub ahead of print] No abstract available.


Evolutionary adaptation in fucosyllactose uptake systems supports bifidobacteria-infant symbiosis.

Sakanaka M, Hansen ME, Gotoh A, Katoh T, Yoshida K, Odamaki T, Yachi H, Sugiyama Y, Kurihara S, Hirose J, Urashima T, Xiao JZ, Kitaoka M, Fukiya S, Yokota A, Lo Leggio L, Abou Hachem M, Katayama T.

Sci Adv. 2019 Aug 28;5(8):eaaw7696. doi: 10.1126/sciadv.aaw7696. eCollection 2019 Aug.


Ingestion of difructose anhydride III partially suppresses the deconjugation and 7α-dehydroxylation of bile acids in rats fed with a cholic acid-supplemented diet.

Lee DG, Hori S, Kohmoto O, Kitta S, Yoshida R, Tanaka Y, Shimizu H, Takahashi K, Nagura T, Uchino H, Fukiya S, Yokota A, Ishizuka S.

Biosci Biotechnol Biochem. 2019 Jul;83(7):1329-1335. doi: 10.1080/09168451.2019.1597617. Epub 2019 Mar 26.


A Transposon Mutagenesis System for Bifidobacterium longum subsp. longum Based on an IS3 Family Insertion Sequence, ISBlo11.

Sakanaka M, Nakakawaji S, Nakajima S, Fukiya S, Abe A, Saburi W, Mori H, Yokota A.

Appl Environ Microbiol. 2018 Aug 17;84(17). pii: e00824-18. doi: 10.1128/AEM.00824-18. Print 2018 Sep 1.


The membrane phospholipid cardiolipin plays a pivotal role in bile acid adaptation by Lactobacillus gasseri JCM1131T.

Kato S, Tobe H, Matsubara H, Sawada M, Sasaki Y, Fukiya S, Morita N, Yokota A.

Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Mar;1864(3):403-412. doi: 10.1016/j.bbalip.2018.06.004. Epub 2018 Jun 5.


Lipoteichoic acids are embedded in cell walls during logarithmic phase, but exposed on membrane vesicles in Lactobacillus gasseri JCM 1131T.

Shiraishi T, Yokota S, Sato Y, Ito T, Fukiya S, Yamamoto S, Sato T, Yokota A.

Benef Microbes. 2018 Jun 15;9(4):653-662. doi: 10.3920/BM2017.0124. Epub 2018 Apr 10.


Bifidobacterium bifidum Extracellular Sialidase Enhances Adhesion to the Mucosal Surface and Supports Carbohydrate Assimilation.

Nishiyama K, Yamamoto Y, Sugiyama M, Takaki T, Urashima T, Fukiya S, Yokota A, Okada N, Mukai T.

mBio. 2017 Oct 3;8(5). pii: e00928-17. doi: 10.1128/mBio.00928-17.


Isolation of six novel 7-oxo- or urso-type secondary bile acid-producing bacteria from rat cecal contents.

Tawthep S, Fukiya S, Lee JY, Hagio M, Ogura Y, Hayashi T, Yokota A.

J Biosci Bioeng. 2017 Nov;124(5):514-522. doi: 10.1016/j.jbiosc.2017.06.002. Epub 2017 Jul 24.


Comprehensive evaluation of the bactericidal activities of free bile acids in the large intestine of humans and rodents.

Watanabe M, Fukiya S, Yokota A.

J Lipid Res. 2017 Jun;58(6):1143-1152. doi: 10.1194/jlr.M075143. Epub 2017 Apr 12.


Pyruvate dehydrogenase complex regulator (PdhR) gene deletion boosts glucose metabolism in Escherichia coli under oxygen-limited culture conditions.

Maeda S, Shimizu K, Kihira C, Iwabu Y, Kato R, Sugimoto M, Fukiya S, Wada M, Yokota A.

J Biosci Bioeng. 2017 Apr;123(4):437-443. doi: 10.1016/j.jbiosc.2016.11.004. Epub 2016 Dec 20.


Structural diversity and biological significance of lipoteichoic acid in Gram-positive bacteria: focusing on beneficial probiotic lactic acid bacteria.

Shiraishi T, Yokota S, Fukiya S, Yokota A.

Biosci Microbiota Food Health. 2016;35(4):147-161. Epub 2016 Jun 9. Review.


Lactobacillus rhamnosus GG increases Toll-like receptor 3 gene expression in murine small intestine ex vivo and in vivo.

Aoki-Yoshida A, Saito S, Fukiya S, Aoki R, Takayama Y, Suzuki C, Sonoyama K.

Benef Microbes. 2016 Jun;7(3):421-9. doi: 10.3920/BM2015.0169. Epub 2016 Mar 25.


Activity of ERK regulates mucin 3 expression and is involved in undifferentiated Caco-2 cell death induced by 3-oxo-C12-homoserine lactone.

Shimizu H, Baba N, Nose T, Taguchi R, Tanaka S, Joe GH, Maseda H, Nomura N, Hagio M, Lee JY, Fukiya S, Yokota A, Ishizuka S, Miyazaki H.

Biosci Biotechnol Biochem. 2015;79(6):937-42. doi: 10.1080/09168451.2015.1006570. Epub 2015 Mar 16.


Isolation and transposition properties of ISBlo11, an active insertion sequence belonging to the IS3 family, from Bifidobacterium longum 105-A.

Sakanaka M, Fukiya S, Kobayashi R, Abe A, Hirayama Y, Kano Y, Yokota A.

FEMS Microbiol Lett. 2015 Apr;362(7). pii: fnv032. doi: 10.1093/femsle/fnv032. Epub 2015 Feb 26.


Mouse models for assessing the cross-protective efficacy of oral non-typhoidal Salmonella vaccine candidates harbouring in-frame deletions of the ATP-dependent protease lon and other genes.

Matsui H, Fukiya S, Kodama-Akaboshi C, Eguchi M, Yamamoto T.

J Med Microbiol. 2015 Mar;64(Pt 3):295-302. doi: 10.1099/jmm.0.000014. Epub 2015 Jan 14.


Complete Genome Sequence of Bifidobacterium longum 105-A, a Strain with High Transformation Efficiency.

Kanesaki Y, Masutani H, Sakanaka M, Shiwa Y, Fujisawa T, Nakamura Y, Yokota A, Fukiya S, Suzuki T, Yoshikawa H.

Genome Announc. 2014 Dec 18;2(6). pii: e01311-14. doi: 10.1128/genomeA.01311-14.


Diet supplementation with cholic acid promotes intestinal epithelial proliferation in rats exposed to γ-radiation.

Hagio M, Shimizu H, Joe GH, Takatsuki M, Shiwaku M, Xu H, Lee JY, Fujii N, Fukiya S, Hara H, Yokota A, Ishizuka S.

Toxicol Lett. 2015 Jan 5;232(1):246-52. doi: 10.1016/j.toxlet.2014.10.011. Epub 2014 Oct 17.


Functional analysis of bifidobacterial promoters in Bifidobacterium longum and Escherichia coli using the α-galactosidase gene as a reporter.

Sakanaka M, Tamai S, Hirayama Y, Onodera A, Koguchi H, Kano Y, Yokota A, Fukiya S.

J Biosci Bioeng. 2014 Nov;118(5):489-95. doi: 10.1016/j.jbiosc.2014.05.002. Epub 2014 Jun 3.


Deoxycholic acid is involved in the proliferation and migration of vascular smooth muscle cells.

Shimizu H, Hagio M, Iwaya H, Tsuneki I, Lee JY, Fukiya S, Yokota A, Miyazaki H, Hara H, Ishizuka S.

J Nutr Sci Vitaminol (Tokyo). 2014;60(6):450-4. doi: 10.3177/jnsv.60.450.


Lacto-N-biosidase encoded by a novel gene of Bifidobacterium longum subspecies longum shows unique substrate specificity and requires a designated chaperone for its active expression.

Sakurama H, Kiyohara M, Wada J, Honda Y, Yamaguchi M, Fukiya S, Yokota A, Ashida H, Kumagai H, Kitaoka M, Yamamoto K, Katayama T.

J Biol Chem. 2013 Aug 30;288(35):25194-206. doi: 10.1074/jbc.M113.484733. Epub 2013 Jul 10.


Contribution of the 7β-hydroxysteroid dehydrogenase from Ruminococcus gnavus N53 to ursodeoxycholic acid formation in the human colon.

Lee JY, Arai H, Nakamura Y, Fukiya S, Wada M, Yokota A.

J Lipid Res. 2013 Nov;54(11):3062-9. doi: 10.1194/jlr.M039834. Epub 2013 Jun 1.


Characterization of a Lactobacillus gasseri JCM 1131T lipoteichoic acid with a novel glycolipid anchor structure.

Shiraishi T, Yokota S, Morita N, Fukiya S, Tomita S, Tanaka N, Okada S, Yokota A.

Appl Environ Microbiol. 2013 May;79(10):3315-8. doi: 10.1128/AEM.00243-13. Epub 2013 Mar 15. Erratum in: Appl Environ Microbiol. 2013 Dec;79(24):7931.


Image analyzing method to evaluate in situ bioluminescence from an obligate anaerobe cultivated under various dissolved oxygen concentrations.

Ninomiya K, Yamada R, Matsumoto M, Fukiya S, Katayama T, Ogino C, Shimizu N.

J Biosci Bioeng. 2013 Feb;115(2):196-9. doi: 10.1016/j.jbiosc.2012.09.006. Epub 2012 Oct 4.


Is bile acid a determinant of the gut microbiota on a high-fat diet?

Yokota A, Fukiya S, Islam KB, Ooka T, Ogura Y, Hayashi T, Hagio M, Ishizuka S.

Gut Microbes. 2012 Sep-Oct;3(5):455-9. Epub 2012 Jul 24. Review.


Development of a double-crossover markerless gene deletion system in Bifidobacterium longum: functional analysis of the α-galactosidase gene for raffinose assimilation.

Hirayama Y, Sakanaka M, Fukuma H, Murayama H, Kano Y, Fukiya S, Yokota A.

Appl Environ Microbiol. 2012 Jul;78(14):4984-94. doi: 10.1128/AEM.00588-12. Epub 2012 May 11.


Technological advances in bifidobacterial molecular genetics: application to functional genomics and medical treatments.

Fukiya S, Hirayama Y, Sakanaka M, Kano Y, Yokota A.

Biosci Microbiota Food Health. 2012;31(2):15-25. doi: 10.12938/bmfh.31.15. Epub 2012 Apr 20. Review.


Bile acid is a host factor that regulates the composition of the cecal microbiota in rats.

Islam KB, Fukiya S, Hagio M, Fujii N, Ishizuka S, Ooka T, Ogura Y, Hayashi T, Yokota A.

Gastroenterology. 2011 Nov;141(5):1773-81. doi: 10.1053/j.gastro.2011.07.046. Epub 2011 Aug 10.


Alterations of glucose metabolism in Escherichia coli mutants defective in respiratory-chain enzymes.

Kihira C, Hayashi Y, Azuma N, Noda S, Maeda S, Fukiya S, Wada M, Matsushita K, Yokota A.

J Biotechnol. 2012 Apr 30;158(4):215-23. doi: 10.1016/j.jbiotec.2011.06.029. Epub 2011 Jun 29.


Ingestion of epilactose, a non-digestible disaccharide, improves postgastrectomy osteopenia and anemia in rats through the promotion of intestinal calcium and iron absorption.

Suzuki T, Nishimukai M, Shinoki A, Taguchi H, Fukiya S, Yokota A, Saburi W, Yamamoto T, Hara H, Matsui H.

J Agric Food Chem. 2010 Oct 13;58(19):10787-92. doi: 10.1021/jf102563y.


Characterization of an insertion sequence-like element, ISBlo15, identified in a size-increased cryptic plasmid pBK283 in Bifidobacterium longum BK28.

Fukiya S, Sugiyama T, Kano Y, Yokota A.

J Biosci Bioeng. 2010 Aug;110(2):141-6. doi: 10.1016/j.jbiosc.2010.02.013. Epub 2010 Mar 15.


Molecular cloning and characterization of the AVR-Pia locus from a Japanese field isolate of Magnaporthe oryzae.

Miki S, Matsui K, Kito H, Otsuka K, Ashizawa T, Yasuda N, Fukiya S, Sato J, Hirayae K, Fujita Y, Nakajima T, Tomita F, Sone T.

Mol Plant Pathol. 2009 May;10(3):361-74. doi: 10.1111/j.1364-3703.2009.00534.x.


Conversion of cholic acid and chenodeoxycholic acid into their 7-oxo derivatives by Bacteroides intestinalis AM-1 isolated from human feces.

Fukiya S, Arata M, Kawashima H, Yoshida D, Kaneko M, Minamida K, Watanabe J, Ogura Y, Uchida K, Itoh K, Wada M, Ito S, Yokota A.

FEMS Microbiol Lett. 2009 Apr;293(2):263-70. doi: 10.1111/j.1574-6968.2009.01531.x. Epub 2009 Feb 23.


Identification of the cellobiose 2-epimerase gene in the genome of Bacteroides fragilis NCTC 9343.

Senoura T, Taguchi H, Ito S, Hamada S, Matsui H, Fukiya S, Yokota A, Watanabe J, Wasaki J, Ito S.

Biosci Biotechnol Biochem. 2009 Feb;73(2):400-6. Epub 2009 Feb 7.


[FISH-flow cytometry, a new tool for the analysis of intestinal microbiota].

Fukiya S, Yokota A.

Seikagaku. 2008 May;80(5):421-5. Review. Japanese. No abstract available.


Population dynamics of Bifidobacterium species in human feces during raffinose administration monitored by fluorescence in situ hybridization-flow cytometry.

Dinoto A, Marques TM, Sakamoto K, Fukiya S, Watanabe J, Ito S, Yokota A.

Appl Environ Microbiol. 2006 Dec;72(12):7739-47. Epub 2006 Oct 20.


Occan, a novel transposon in the Fot1 family, is ubiquitously found in several Magnaporthe grisea isolates.

Kito H, Takahashi Y, Sato J, Fukiya S, Sone T, Tomita F.

Curr Genet. 2003 Mar;42(6):322-31. Epub 2003 Feb 8.


Identification of a putative vacuolar serine protease gene in the rice blast fungus, Magnaporthe grisea.

Fukiya S, Kuge T, Tanishima T, Sone T, Kamakura T, Yamaguchi I, Tomita F.

Biosci Biotechnol Biochem. 2002 Mar;66(3):663-6.


Molecular structure of rDNA repeat unit in Magnaporthe grisea.

Sone T, Fukiya S, Kodama M, Tomita F.

Biosci Biotechnol Biochem. 2000 Aug;64(8):1733-6.


Active and passive immunization for tetrodotoxin in mice.

Fukiya S, Matsumura K.

Toxicon. 1992 Dec;30(12):1631-4.


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