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Items: 1 to 50 of 193

1.

Development of α-Gal Antibody Conjugates for Increasing Immune Response by Recruiting Natural Antibodies.

Sianturi J, Manabe Y, Li HS, Chiu LT, Chang TC, Tokunaga K, Kabayama K, Tanemura M, Takamatsu S, Miyoshi E, Hung SC, Fukase K.

Angew Chem Int Ed Engl. 2019 Feb 12. doi: 10.1002/anie.201812914. [Epub ahead of print]

PMID:
30756454
2.

The NLRP6 Inflammasome Recognizes Lipoteichoic Acid and Regulates Gram-Positive Pathogen Infection.

Hara H, Seregin SS, Yang D, Fukase K, Chamaillard M, Alnemri ES, Inohara N, Chen GY, Núñez G.

Cell. 2018 Nov 29;175(6):1651-1664.e14. doi: 10.1016/j.cell.2018.09.047. Epub 2018 Nov 1.

PMID:
30392956
3.

FBXW7 modulates malignant potential and cisplatin-induced apoptosis in cholangiocarcinoma through NOTCH1 and MCL1.

Mori A, Masuda K, Ohtsuka H, Shijo M, Ariake K, Fukase K, Sakata N, Mizuma M, Morikawa T, Hayashi H, Nakagawa K, Motoi F, Naitoh T, Fujishima F, Unno M.

Cancer Sci. 2018 Dec;109(12):3883-3895. doi: 10.1111/cas.13829. Epub 2018 Nov 5.

4.

NPC1L1-dependent intestinal cholesterol absorption requires ganglioside GM3 in membrane microdomains.

Nihei W, Nagafuku M, Hayamizu H, Odagiri Y, Tamura Y, Kikuchi Y, Veillon L, Kanoh H, Inamori KI, Arai K, Kabayama K, Fukase K, Inokuchi JI.

J Lipid Res. 2018 Nov;59(11):2181-2187. doi: 10.1194/jlr.M089201. Epub 2018 Sep 21.

PMID:
30242108
5.

Single-Step Per-O-Sulfonation of Sugar Oligomers with Concomitant 1,6-Anhydro Bridge Formation for Binding Fibroblast Growth Factors.

Yeh CJ, Ku CC, Lin WC, Fan CY, Zulueta MML, Manabe Y, Fukase K, Li YK, Hung SC.

Chembiochem. 2019 Jan 18;20(2):237-240. doi: 10.1002/cbic.201800464. Epub 2018 Nov 26.

PMID:
30239102
6.

Bradyrhizobium Lipid A: Immunological Properties and Molecular Basis of Its Binding to the Myeloid Differentiation Protein-2/Toll-Like Receptor 4 Complex.

Lembo-Fazio L, Billod JM, Di Lorenzo F, Paciello I, Pallach M, Vaz-Francisco S, Holgado A, Beyaert R, Fresno M, Shimoyama A, Lanzetta R, Fukase K, Gully D, Giraud E, Martín-Santamaría S, Bernardini ML, Silipo A.

Front Immunol. 2018 Aug 14;9:1888. doi: 10.3389/fimmu.2018.01888. eCollection 2018.

7.

Expanding the Applicability of the Metal Labeling of Biomolecules by the RIKEN Click Reaction: A Case Study with Gallium-68 Positron Emission Tomography.

Nakamoto Y, Pradipta AR, Mukai H, Zouda M, Watanabe Y, Kurbangalieva A, Ahmadi P, Manabe Y, Fukase K, Tanaka K.

Chembiochem. 2018 Oct 4;19(19):2055-2060. doi: 10.1002/cbic.201800335. Epub 2018 Sep 14.

PMID:
30066425
8.

Branched Sialylated N-glycans Are Accumulated in Brain Synaptosomes and Interact with Siglec-H.

Handa-Narumi M, Yoshimura T, Konishi H, Fukata Y, Manabe Y, Tanaka K, Bao GM, Kiyama H, Fukase K, Ikenaka K.

Cell Struct Funct. 2018 Aug 25;43(2):141-152. doi: 10.1247/csf.18009. Epub 2018 Jul 20.

9.

The second and third amino acids of Pam2 lipopeptides are key for the proliferation of cytotoxic T cells.

Takeda Y, Azuma M, Hatsugai R, Fujimoto Y, Hashimoto M, Fukase K, Matsumoto M, Seya T.

Innate Immun. 2018 Jul;24(5):323-331. doi: 10.1177/1753425918777598. Epub 2018 May 31.

PMID:
29848176
10.

Syntheses and Immunological Evaluation of Self-Adjuvanting Clustered N-Acetyl and N-Propionyl Sialyl-Tn Combined with a T-helper Cell Epitope as Antitumor Vaccine Candidates.

Chang TC, Manabe Y, Fujimoto Y, Ohshima S, Kametani Y, Kabayama K, Nimura Y, Lin CC, Fukase K.

Angew Chem Int Ed Engl. 2018 Jul 2;57(27):8219-8224. doi: 10.1002/anie.201804437. Epub 2018 Jun 7.

PMID:
29768704
11.

Time-lapse monitoring of TLR2 ligand internalization with newly developed fluorescent probes.

Arai Y, Yokoyama K, Kawahara Y, Feng Q, Ohta I, Shimoyama A, Inuki S, Fukase K, Kabayama K, Fujimoto Y.

Org Biomol Chem. 2018 May 23;16(20):3824-3830. doi: 10.1039/c7ob03205f.

PMID:
29745411
12.

Convergent Synthesis of a Bisecting N-Acetylglucosamine (GlcNAc)-Containing N-Glycan.

Manabe Y, Shomura H, Minamoto N, Nagasaki M, Takakura Y, Tanaka K, Silipo A, Molinaro A, Fukase K.

Chem Asian J. 2018 Jun 18;13(12):1544-1551. doi: 10.1002/asia.201800367. Epub 2018 May 25.

PMID:
29665315
13.

Lymphoid tissue-resident Alcaligenes LPS induces IgA production without excessive inflammatory responses via weak TLR4 agonist activity.

Shibata N, Kunisawa J, Hosomi K, Fujimoto Y, Mizote K, Kitayama N, Shimoyama A, Mimuro H, Sato S, Kishishita N, Ishii KJ, Fukase K, Kiyono H.

Mucosal Immunol. 2018 May;11(3):693-702. doi: 10.1038/mi.2017.103. Epub 2018 Feb 7.

PMID:
29411777
14.

[Multidisciplinary Therapy with Gemcitabine and Nab-Paclitaxel for Unresectable Pancreatic Cancer].

Motoi F, Takadate T, Maeda S, Ariake K, Masuda K, Ishida M, Fukase K, Mizuma M, Ohtsuka H, Sakata N, Hayashi H, Nakagawa K, Morikawa T, Naitoh T, Unno M.

Gan To Kagaku Ryoho. 2017 Nov;44(12):1241-1244. Japanese.

PMID:
29394594
15.

Safety and tolerability of selumetinib as a monotherapy, or in combination with docetaxel as second-line therapy, in Japanese patients with advanced solid malignancies or non-small cell lung cancer.

Seto T, Hirai F, Saka H, Kogure Y, Yoh K, Niho S, Fukase K, Shimada H, Sasai M, Fukino K.

Jpn J Clin Oncol. 2018 Jan 1;48(1):31-42. doi: 10.1093/jjco/hyx144.

PMID:
29136201
16.

18-Fluorodeoxyglucose Positron Emission Tomography Predicts Recurrence in Resected Pancreatic Ductal Adenocarcinoma.

Ariake K, Motoi F, Shimomura H, Mizuma M, Maeda S, Terao C, Tatewaki Y, Ohtsuka H, Fukase K, Masuda K, Hayashi H, Takadate T, Naitoh T, Taki Y, Unno M.

J Gastrointest Surg. 2018 Feb;22(2):279-287. doi: 10.1007/s11605-017-3627-3. Epub 2017 Nov 8.

PMID:
29119533
17.

The comparative anatomy of the folds, fossae, and adhesions around the duodenojejunal flexure in mammals.

Ishida M, Sakata N, Ise I, Ono T, Shimura M, Ishii K, Murakami M, Takadate T, Aoki T, Kudo K, Ohnuma S, Fukase K, Ohtsuka H, Mizuma M, Hayashi H, Nakagawa K, Morikawa T, Motoi F, Naitoh T, Unno M.

Folia Morphol (Warsz). 2018;77(2):286-292. doi: 10.5603/FM.a2017.0089. Epub 2017 Oct 24.

18.

Hyponatremia with Loss of High Signal Intensity in the Posterior Pituitary Lobe on T1-weighted Magnetic Resonance Imaging.

Kitagawa M, Yamanaka Y, Adachi T, Ito J, Fukase K, Ohta I, Katagiri T.

Intern Med. 2017 Dec 1;56(23):3205-3209. doi: 10.2169/internalmedicine.8616-16. Epub 2017 Oct 11.

19.

Diabetic Hemichorea-hemiballism after Prompt Improvement in Hyperglycemia.

Kitagawa M, Yamanaka Y, Adachi T, Ito J, Fukase K, Ohta I, Katagiri T.

Intern Med. 2017 Nov 15;56(22):3073-3076. doi: 10.2169/internalmedicine.8615-16. Epub 2017 Sep 25.

20.

A Comprehensive Study of the Interaction between Peptidoglycan Fragments and the Extracellular Domain of Mycobacterium tuberculosis Ser/Thr Kinase PknB.

Wang Q, Marchetti R, Prisic S, Ishii K, Arai Y, Ohta I, Inuki S, Uchiyama S, Silipo A, Molinaro A, Husson RN, Fukase K, Fujimoto Y.

Chembiochem. 2017 Nov 2;18(21):2094-2098. doi: 10.1002/cbic.201700385. Epub 2017 Sep 14.

21.

Synthetic analogs of an Entamoeba histolytica glycolipid designed to combat intracellular Leishmania infection.

Choy SL, Bernin H, Aiba T, Bifeld E, Lender SC, Mühlenpfordt M, Noll J, Eick J, Marggraff C, Niss H, Roldán NG, Tanaka S, Kitamura M, Fukase K, Clos J, Tannich E, Fujimoto Y, Lotter H.

Sci Rep. 2017 Aug 25;7(1):9472. doi: 10.1038/s41598-017-09894-8.

22.

Funiculosin variants and phosphorylated derivatives promote innate immune responses via the Toll-like receptor 4/myeloid differentiation factor-2 complex.

Okamoto N, Mizote K, Honda H, Saeki A, Watanabe Y, Yamaguchi-Miyamoto T, Fukui R, Tanimura N, Motoi Y, Akashi-Takamura S, Kato T, Fujishita S, Kimura T, Ohto U, Shimizu T, Hirokawa T, Miyake K, Fukase K, Fujimoto Y, Nagai Y, Takatsu K.

J Biol Chem. 2017 Sep 15;292(37):15378-15394. doi: 10.1074/jbc.M117.791780. Epub 2017 Jul 28.

23.

Total Synthesis of Cardiolipins Containing Chiral Cyclopropane Fatty Acids.

Inuki S, Ohta I, Ishibashi S, Takamatsu M, Fukase K, Fujimoto Y.

J Org Chem. 2017 Aug 4;82(15):7832-7838. doi: 10.1021/acs.joc.7b00945. Epub 2017 Jul 19.

PMID:
28682614
24.

Calcineurin inhibitors exacerbate coronary arteritis via the MyD88 signalling pathway in a murine model of Kawasaki disease.

Murata K, Motomura Y, Tanaka T, Kanno S, Yano T, Onimaru M, Shimoyama A, Nishio H, Sakai Y, Oh-Hora M, Hara H, Fukase K, Takada H, Masuda S, Ohga S, Yamasaki S, Hara T.

Clin Exp Immunol. 2017 Oct;190(1):54-67. doi: 10.1111/cei.13002. Epub 2017 Jul 21.

25.

Predictive risk factors for peritoneal recurrence after pancreatic cancer resection and strategies for its prevention.

Ariake K, Motoi F, Ohtsuka H, Fukase K, Masuda K, Mizuma M, Hayashi H, Nakagawa K, Morikawa T, Maeda S, Takadate T, Naitoh T, Egawa S, Unno M.

Surg Today. 2017 Dec;47(12):1434-1442. doi: 10.1007/s00595-017-1531-9. Epub 2017 Apr 22.

PMID:
28434080
26.

Employing BINOL-Phosphoroselenoyl Chloride for Selective Inositol Phosphorylation and Synthesis of Glycosyl Inositol Phospholipid from Entamoeba histolytica.

Aiba T, Suehara S, Choy SL, Maekawa Y, Lotter H, Murai T, Inuki S, Fukase K, Fujimoto Y.

Chemistry. 2017 Jun 16;23(34):8304-8308. doi: 10.1002/chem.201701298. Epub 2017 May 24.

PMID:
28390155
27.

Development of α1,6-fucosyltransferase inhibitors through the diversity-oriented syntheses of GDP-fucose mimics using the coupling between alkyne and sulfonyl azide.

Manabe Y, Kasahara S, Takakura Y, Yang X, Takamatsu S, Kamada Y, Miyoshi E, Yoshidome D, Fukase K.

Bioorg Med Chem. 2017 Jun 1;25(11):2844-2850. doi: 10.1016/j.bmc.2017.02.036. Epub 2017 Feb 28.

PMID:
28284868
28.

Application of Quantitative Targeted Absolute Proteomics to Profile Protein Expression Changes of Hepatic Transporters and Metabolizing Enzymes During Cholic Acid-Promoted Liver Regeneration.

Miura T, Tachikawa M, Ohtsuka H, Fukase K, Nakayama S, Sakata N, Motoi F, Naitoh T, Katayose Y, Uchida Y, Ohtsuki S, Terasaki T, Unno M.

J Pharm Sci. 2017 Sep;106(9):2499-2508. doi: 10.1016/j.xphs.2017.02.018. Epub 2017 Feb 27.

PMID:
28249806
29.

MK2461, a Multitargeted Kinase Inhibitor, Suppresses the Progression of Pancreatic Cancer by Disrupting the Interaction Between Pancreatic Cancer Cells and Stellate Cells.

Inoue K, Ohtsuka H, Tachikawa M, Motoi F, Shijo M, Douchi D, Kawasaki S, Kawaguchi K, Masuda K, Fukase K, Naitoh T, Katayose Y, Egawa S, Unno M, Terasaki T.

Pancreas. 2017 Apr;46(4):557-566. doi: 10.1097/MPA.0000000000000778.

PMID:
28196027
30.

A case of adult undifferentiated embryonal sarcoma of the liver successfully treated with right trisectionectomy: a case report.

Mori A, Fukase K, Masuda K, Sakata N, Mizuma M, Ohtsuka H, Morikawa T, Nakagawa K, Hayashi H, Motoi F, Naitoh T, Murakami K, Unno M.

Surg Case Rep. 2017 Dec;3(1):19. doi: 10.1186/s40792-017-0295-1. Epub 2017 Jan 31.

31.

Product Selectivity of Esterification of L-Aspartic Acid and L-Glutamic Acid Using Chlorotrimethylsilane.

Takaishi T, Izumi M, Ota R, Inoue C, Kiyota H, Fukase K.

Nat Prod Commun. 2017 Feb;12(2):247-249.

PMID:
30428223
32.

[A Case of Successful Stomach-Preserving Pancreaticoduodenectomy with Celiac Artery Resection after Neoadjuvant Chemoradiation Therapy for Pancreatic Cancer with Hepatic Arterial Variation].

Kyakumoto Y, Mizuma M, Abe T, Takadate T, Fukase K, Otsuka H, Sakata N, Nakagawa K, Morikawa T, Hayashi H, Naitoh T, Motoi F, Kanno A, Shimosegawa T, Unno M.

Gan To Kagaku Ryoho. 2016 Nov;43(12):1966-1968. Japanese.

PMID:
28133191
33.

Locally advanced pancreatic cancer successfully treated by distal pancreatectomy with celiac axis resection (DP-CAR) after S-1 with radiation therapy followed by gemcitabine/nab-paclitaxel therapy: a case report.

Ariake K, Motoi F, Mizuma M, Murakami K, Takadate T, Ohtsuka H, Fukase K, Masuda K, Hayashi H, Nakagawa K, Sakata N, Morikawa T, Maeda S, Naitoh T, Egawa S, Unno M.

Surg Case Rep. 2017 Dec;3(1):15. doi: 10.1186/s40792-017-0290-6. Epub 2017 Jan 18.

34.

Ectonucleotidase CD39-driven control of postinfarction myocardial repair and rupture.

Sutton NR, Hayasaki T, Hyman MC, Anyanwu AC, Liao H, Petrovic-Djergovic D, Badri L, Baek AE, Walker N, Fukase K, Kanthi Y, Visovatti SH, Horste EL, Ray JJ, Goonewardena SN, Pinsky DJ.

JCI Insight. 2017 Jan 12;2(1):e89504. doi: 10.1172/jci.insight.89504.

35.

Synthesis of Peptidoglycan Fragments from Enterococcus faecalis with Fmoc-Strategy for Glycan Elongation.

Wang N, Hasegawa H, Huang CY, Fukase K, Fujimoto Y.

Chem Asian J. 2017 Jan 3;12(1):27-30. doi: 10.1002/asia.201601357. Epub 2016 Dec 2.

PMID:
27868361
36.

Discovery of a Novel Scaffold as an Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitor Based on the Pyrrolopiperazinone Alkaloid, Longamide B.

Shiokawa Z, Kashiwabara E, Yoshidome D, Fukase K, Inuki S, Fujimoto Y.

ChemMedChem. 2016 Dec 16;11(24):2682-2689. doi: 10.1002/cmdc.201600446. Epub 2016 Dec 5.

PMID:
27863031
37.

A Reduction-Based Sensor for Acrolein Conjugates with the Inexpensive Nitrobenzene as an Alternative to Monoclonal Antibody.

Takamatsu M, Fukase K, Oka R, Kitazume S, Taniguchi N, Tanaka K.

Sci Rep. 2016 Oct 26;6:35872. doi: 10.1038/srep35872.

38.

Chemical Synthesis of a Complex-Type N-Glycan Containing a Core Fucose.

Nagasaki M, Manabe Y, Minamoto N, Tanaka K, Silipo A, Molinaro A, Fukase K.

J Org Chem. 2016 Nov 18;81(22):10600-10616. Epub 2016 Oct 27.

PMID:
27775350
39.

Isolated Polar Amino Acid Residues Modulate Lipid Binding in the Large Hydrophobic Cavity of CD1d.

Inuki S, Aiba T, Hirata N, Ichihara O, Yoshidome D, Kita S, Maenaka K, Fukase K, Fujimoto Y.

ACS Chem Biol. 2016 Nov 18;11(11):3132-3139. Epub 2016 Oct 4.

PMID:
27648599
40.

One-Pot Evolution of Ageladine A through a Bio-Inspired Cascade towards Selective Modulators of Neuronal Differentiation.

Iwata T, Otsuka S, Tsubokura K, Kurbangalieva A, Arai D, Fukase K, Nakao Y, Tanaka K.

Chemistry. 2016 Oct 4;22(41):14707-16. doi: 10.1002/chem.201602651. Epub 2016 Aug 25.

PMID:
27557614
41.

Characterization of a Novel d-Glycero-d-talo-oct-2-ulosonic acid-substituted Lipid A Moiety in the Lipopolysaccharide Produced by the Acetic Acid Bacterium Acetobacter pasteurianus NBRC 3283.

Hashimoto M, Ozono M, Furuyashiki M, Baba R, Hashiguchi S, Suda Y, Fukase K, Fujimoto Y.

J Biol Chem. 2016 Sep 30;291(40):21184-21194. Epub 2016 Aug 18.

42.

Regioselective phosphorylation of myo-inositol with BINOL-derived phosphoramidites and its application for protozoan lysophosphatidylinositol.

Aiba T, Sato M, Umegaki D, Iwasaki T, Kambe N, Fukase K, Fujimoto Y.

Org Biomol Chem. 2016 Jul 12;14(28):6672-5. doi: 10.1039/c6ob01062h.

PMID:
27326923
43.

Development of a simple assay system for protein-stabilizing efficiency based on hemoglobin protection against denaturation and measurement of the cooperative effect of mixing protein stabilizers.

Chen S, Manabe Y, Minamoto N, Saiki N, Fukase K.

Biosci Biotechnol Biochem. 2016 Oct;80(10):1874-8. doi: 10.1080/09168451.2016.1189317. Epub 2016 Jun 2.

PMID:
27253914
44.

Efficient Synthesis of the Disialylated Tetrasaccharide Motif in N-Glycans through an Amide-Protection Strategy.

Zhou J, Manabe Y, Tanaka K, Fukase K.

Chem Asian J. 2016 May 6;11(9):1436-40. doi: 10.1002/asia.201600139. Epub 2016 Apr 8.

PMID:
26929048
45.

Peptidoglycan microarray as a novel tool to explore protein-ligand recognition.

Wang N, Hirata A, Nokihara K, Fukase K, Fujimoto Y.

Biopolymers. 2016 Nov 4;106(4):422-9. doi: 10.1002/bip.22807.

PMID:
26773558
46.

Synthesis of characteristic Mycobacterium peptidoglycan (PGN) fragments utilizing with chemoenzymatic preparation of meso-diaminopimelic acid (DAP), and their modulation of innate immune responses.

Wang Q, Matsuo Y, Pradipta AR, Inohara N, Fujimoto Y, Fukase K.

Org Biomol Chem. 2016 Jan 21;14(3):1013-23. doi: 10.1039/c5ob02145f. Epub 2015 Dec 3.

PMID:
26631868
47.

Silencing of LRRFIP1 reverses the epithelial-mesenchymal transition via inhibition of the Wnt/β-catenin signaling pathway.

Douchi D, Ohtsuka H, Ariake K, Masuda K, Kawasaki S, Kawaguchi K, Fukase K, Oikawa M, Motoi F, Naitoh T, Katayose Y, Egawa S, Unno M.

Cancer Lett. 2015 Aug 28;365(1):132-40. doi: 10.1016/j.canlet.2015.05.023. Epub 2015 Jun 3.

PMID:
26047573
48.

Chemical Approach to a Whole Body Imaging of Sialo-N-Linked Glycans.

Tanaka K, Fukase K.

Top Curr Chem. 2015;367:201-30. doi: 10.1007/128_2014_603. Review.

PMID:
25971916
49.

Long-term outcomes after extrahepatic excision of congenital choladocal cysts: 30 years of experience at a single center.

Ohtsuka H, Fukase K, Yoshida H, Motoi F, Hayashi H, Morikawa T, Okada T, Nakagawa K, Naitoh T, Katayose Y, Unno M.

Hepatogastroenterology. 2015 Jan-Feb;62(137):1-5.

PMID:
25911857
50.

[A case of pancreatic cancer with local recurrence and liver metastases eight years after surgery].

Taniguchi H, Mizuma M, Motoi F, Abe T, Okada R, Kawaguchi K, Karasawa H, Masuda K, Yabuuchi S, Fukase K, Sakata N, Okada T, Nakagawa K, Hayashi H, Morikawa T, Yoshida H, Naito T, Katayose Y, Egawa S, Unno M.

Gan To Kagaku Ryoho. 2014 Nov;41(12):2193-5. Review. Japanese.

PMID:
25731467

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