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Items: 1 to 50 of 366

1.

Cooperative action of APJ and α1A-adrenergic receptor in vascular smooth muscle cells induces vasoconstriction.

Nagano K, Kwon C, Ishida J, Hashimoto T, Kim JD, Kishikawa N, Murao M, Kimura K, Kasuya Y, Kimura S, Chen YC, Tsuchimochi H, Shirai M, Pearson JT, Fukamizu A.

J Biochem. 2019 Sep 3. pii: mvz071. doi: 10.1093/jb/mvz071. [Epub ahead of print]

PMID:
31504625
2.

The N-terminal sequence of murine PRMT5 variant 2 is required for Hsp70 interaction and CHIP ligase-mediated degradation.

Lu W, Kim JD, Tabara S, Kwon C, Mizukami H, Kimura K, Fukamizu A.

Biochem Biophys Res Commun. 2019 Jul 5;514(4):1185-1191. doi: 10.1016/j.bbrc.2019.05.077. Epub 2019 May 16.

PMID:
31103260
3.

Transvection-like interchromosomal interaction is not observed at the transcriptional level when tested in the Rosa26 locus in mouse.

Tanimoto K, Matsuzaki H, Okamura E, Ushiki A, Fukamizu A, Engel JD.

PLoS One. 2019 Feb 14;14(2):e0203099. doi: 10.1371/journal.pone.0203099. eCollection 2019.

4.

Tricarboxylic acid cycle activity suppresses acetylation of mitochondrial proteins during early embryonic development in Caenorhabditis elegans.

Hada K, Hirota K, Inanobe A, Kako K, Miyata M, Araoi S, Matsumoto M, Ohta R, Arisawa M, Daitoku H, Hanada T, Fukamizu A.

J Biol Chem. 2019 Mar 1;294(9):3091-3099. doi: 10.1074/jbc.RA118.004726. Epub 2019 Jan 3.

PMID:
30606736
5.

KDM5D-mediated H3K4 demethylation is required for sexually dimorphic gene expression in mouse embryonic fibroblasts.

Mizukami H, Kim JD, Tabara S, Lu W, Kwon C, Nakashima M, Fukamizu A.

J Biochem. 2019 Apr 1;165(4):335-342. doi: 10.1093/jb/mvy106.

PMID:
30541083
6.

PRMT1 Deficiency in Mouse Juvenile Heart Induces Dilated Cardiomyopathy and Reveals Cryptic Alternative Splicing Products.

Murata K, Lu W, Hashimoto M, Ono N, Muratani M, Nishikata K, Kim JD, Ebihara S, Ishida J, Fukamizu A.

iScience. 2018 Oct 26;8:200-213. doi: 10.1016/j.isci.2018.09.023. Epub 2018 Oct 2.

7.

Emerging impacts of biological methylation on genetic information.

Kako K, Kim JD, Fukamizu A.

J Biochem. 2019 Jan 1;165(1):9-18. doi: 10.1093/jb/mvy075. Review.

PMID:
30219914
8.

Synthetic DNA fragments bearing ICR cis elements become differentially methylated and recapitulate genomic imprinting in transgenic mice.

Matsuzaki H, Okamura E, Kuramochi D, Ushiki A, Hirakawa K, Fukamizu A, Tanimoto K.

Epigenetics Chromatin. 2018 Jun 29;11(1):36. doi: 10.1186/s13072-018-0207-z.

9.

Gestational changes in PRMT1 expression of murine placentas.

Sato A, Kim JD, Mizukami H, Nakashima M, Kako K, Ishida J, Itakura A, Takeda S, Fukamizu A.

Placenta. 2018 May;65:47-54. doi: 10.1016/j.placenta.2018.04.001. Epub 2018 Apr 7.

PMID:
29908641
10.

Calreticulin and integrin alpha dissociation induces anti-inflammatory programming in animal models of inflammatory bowel disease.

Ohkuro M, Kim JD, Kuboi Y, Hayashi Y, Mizukami H, Kobayashi-Kuramochi H, Muramoto K, Shirato M, Michikawa-Tanaka F, Moriya J, Kozaki T, Takase K, Chiba K, Agarwala KL, Kimura T, Kotake M, Kawahara T, Yoneda N, Hirota S, Azuma H, Ozasa-Komura N, Ohashi Y, Muratani M, Kimura K, Hishinuma I, Fukamizu A.

Nat Commun. 2018 May 17;9(1):1982. doi: 10.1038/s41467-018-04420-4.

11.

PRMT-5 converts monomethylarginines into symmetrical dimethylarginines in Caenorhabditis elegans.

Kanou A, Kako K, Hirota K, Fukamizu A.

J Biochem. 2018 Apr 1;163(4):351. doi: 10.1093/jb/mvy024. No abstract available.

PMID:
29471522
12.

rRNA adenine methylation requires T07A9.8 gene as rram-1 in Caenorhabditis elegans.

Yokoyama W, Hirota K, Wan H, Sumi N, Miyata M, Araoi S, Nomura N, Kako K, Fukamizu A.

J Biochem. 2018 Jun 1;163(6):465-474. doi: 10.1093/jb/mvy018.

PMID:
29385568
13.

Single-cell nanobiopsy reveals compartmentalization of mRNAs within neuronal cells.

Tóth EN, Lohith A, Mondal M, Guo J, Fukamizu A, Pourmand N.

J Biol Chem. 2018 Mar 30;293(13):4940-4951. doi: 10.1074/jbc.M117.800763. Epub 2018 Jan 29.

14.

The GATA transcription factor ELT-2 modulates both the expression and methyltransferase activity of PRMT-1 in Caenorhabditis elegans.

Araoi S, Daitoku H, Yokoyama A, Kako K, Hirota K, Fukamizu A.

J Biochem. 2018 May 1;163(5):433-440. doi: 10.1093/jb/mvy012.

PMID:
29361115
15.

Homeostatic Response of Mouse renin Gene Transcription in a Hypertensive Environment Is Mediated by a Novel 5' Enhancer.

Ushiki A, Matsuzaki H, Fukamizu A, Tanimoto K.

Mol Cell Biol. 2018 Mar 15;38(7). pii: e00566-17. doi: 10.1128/MCB.00566-17. Print 2018 Apr 1.

16.

Sleep/Wake Behaviors in Mice During Pregnancy and Pregnancy-Associated Hypertensive Mice.

Komiya H, Miyoshi C, Iwasaki K, Hotta-Hirashima N, Ikkyu A, Kanno S, Honda T, Gosho M, Hamada H, Satoh T, Fukamizu A, Funato H, Yanagisawa M.

Sleep. 2018 Mar 1;41(3). doi: 10.1093/sleep/zsx209.

PMID:
29309677
17.

Nucleomethylin deficiency impairs embryonic erythropoiesis.

Murakami S, Suzuki T, Yokoyama W, Yagi S, Matsumura K, Nakajima Y, Harigae H, Fukamizu A, Motohashi H.

J Biochem. 2018 May 1;163(5):413-423. doi: 10.1093/jb/mvx086.

PMID:
29244083
18.

Loss of Apela Peptide in Mice Causes Low Penetrance Embryonic Lethality and Defects in Early Mesodermal Derivatives.

Freyer L, Hsu CW, Nowotschin S, Pauli A, Ishida J, Kuba K, Fukamizu A, Schier AF, Hoodless PA, Dickinson ME, Hadjantonakis AK.

Cell Rep. 2017 Aug 29;20(9):2116-2130. doi: 10.1016/j.celrep.2017.08.014.

19.

Erratum: Distinct neural mechanisms for the control of thirst and salt appetite in the subfornical organ.

Matsuda T, Hiyama TY, Niimura F, Matsusaka T, Fukamizu A, Kobayashi K, Kobayashi K, Noda M.

Nat Neurosci. 2017 May 25;20(6):896. doi: 10.1038/nn0617-896b. No abstract available.

PMID:
28542153
20.

Nrf2 inactivation enhances placental angiogenesis in a preeclampsia mouse model and improves maternal and fetal outcomes.

Nezu M, Souma T, Yu L, Sekine H, Takahashi N, Wei AZ, Ito S, Fukamizu A, Zsengeller ZK, Nakamura T, Hozawa A, Karumanchi SA, Suzuki N, Yamamoto M.

Sci Signal. 2017 May 16;10(479). pii: eaam5711. doi: 10.1126/scisignal.aam5711.

PMID:
28512147
21.

ELABELA-APJ axis protects from pressure overload heart failure and angiotensin II-induced cardiac damage.

Sato T, Sato C, Kadowaki A, Watanabe H, Ho L, Ishida J, Yamaguchi T, Kimura A, Fukamizu A, Penninger JM, Reversade B, Ito H, Imai Y, Kuba K.

Cardiovasc Res. 2017 Jun 1;113(7):760-769. doi: 10.1093/cvr/cvx061.

PMID:
28371822
22.

Nrf2 Improves Leptin and Insulin Resistance Provoked by Hypothalamic Oxidative Stress.

Yagishita Y, Uruno A, Fukutomi T, Saito R, Saigusa D, Pi J, Fukamizu A, Sugiyama F, Takahashi S, Yamamoto M.

Cell Rep. 2017 Feb 21;18(8):2030-2044. doi: 10.1016/j.celrep.2017.01.064.

23.

PRMT-5 converts monomethylarginines into symmetrical dimethylarginines in Caenorhabditis elegans.

Kanou A, Kako K, Hirota K, Fukamizu A.

J Biochem. 2017 Feb 1;161(2):231-235. doi: 10.1093/jb/mvw066.

PMID:
28173048
24.

Simultaneous ablation of prmt-1 and prmt-5 abolishes asymmetric and symmetric arginine dimethylations in Caenorhabditis elegans.

Hirota K, Shigekawa C, Araoi S, Sha L, Inagawa T, Kanou A, Kako K, Daitoku H, Fukamizu A.

J Biochem. 2017 Jun 1;161(6):521-527. doi: 10.1093/jb/mvw101.

PMID:
28158808
25.

Possible roles of the transcription factor Nrf1 (NFE2L1) in neural homeostasis by regulating the gene expression of deubiquitinating enzymes.

Taniguchi H, Okamuro S, Koji M, Waku T, Kubo K, Hatanaka A, Sun Y, Chowdhury AMMA, Fukamizu A, Kobayashi A.

Biochem Biophys Res Commun. 2017 Feb 26;484(1):176-183. doi: 10.1016/j.bbrc.2017.01.038. Epub 2017 Jan 11.

PMID:
28088524
26.

Hydralazine is involved in tele-methylhistamine metabolism by inhibiting monoamine oxidase B in pregnancy-associated hypertensive mice.

Kawasaki S, Kako K, Nagashima Y, Kanou A, Ishida J, Fukamizu A.

J Biochem. 2017 Feb 1;161(2):155-158. doi: 10.1093/jb/mvw090.

PMID:
28069864
27.

Angiodysplasia in embryo lacking protein arginine methyltransferase 1 in vascular endothelial cells.

Ishimaru T, Ishida J, Kim JD, Mizukami H, Hara K, Hashimoto M, Yagami KI, Sugiyama F, Fukamizu A.

J Biochem. 2017 Mar 1;161(3):255-258. doi: 10.1093/jb/mvw095.

PMID:
28003433
28.

Asymmetric Arginine Dimethylation Modulates Mitochondrial Energy Metabolism and Homeostasis in Caenorhabditis elegans.

Sha L, Daitoku H, Araoi S, Kaneko Y, Takahashi Y, Kako K, Fukamizu A.

Mol Cell Biol. 2017 Mar 1;37(6). pii: e00504-16. doi: 10.1128/MCB.00504-16. Print 2017 Mar 15.

29.

Distinct neural mechanisms for the control of thirst and salt appetite in the subfornical organ.

Matsuda T, Hiyama TY, Niimura F, Matsusaka T, Fukamizu A, Kobayashi K, Kobayashi K, Noda M.

Nat Neurosci. 2017 Feb;20(2):230-241. doi: 10.1038/nn.4463. Epub 2016 Dec 19. Erratum in: Nat Neurosci. 2017 May 25;20(6):896.

PMID:
27991901
30.

Long-Range Control of Renin Gene Expression in Tsukuba Hypertensive Mice.

Ushiki A, Matsuzaki H, Ishida J, Fukamizu A, Tanimoto K.

PLoS One. 2016 Nov 18;11(11):e0166974. doi: 10.1371/journal.pone.0166974. eCollection 2016.

31.

Unique pH dynamics in GABAergic synaptic vesicles illuminates the mechanism and kinetics of GABA loading.

Egashira Y, Takase M, Watanabe S, Ishida J, Fukamizu A, Kaneko R, Yanagawa Y, Takamori S.

Proc Natl Acad Sci U S A. 2016 Sep 20;113(38):10702-7. doi: 10.1073/pnas.1604527113. Epub 2016 Sep 6.

32.

Non-transcriptional Function of FOXO1/DAF-16 Contributes to Translesion DNA Synthesis.

Daitoku H, Kaneko Y, Yoshimochi K, Matsumoto K, Araoi S, Sakamaki JI, Takahashi Y, Fukamizu A.

Mol Cell Biol. 2016 Nov;36(21):2755-2766. doi: 10.1128/MCB.00265-16. Epub 2016 Aug 22.

33.

Detection of LacZ-Positive Cells in Living Tissue with Single-Cell Resolution.

Doura T, Kamiya M, Obata F, Yamaguchi Y, Hiyama TY, Matsuda T, Fukamizu A, Noda M, Miura M, Urano Y.

Angew Chem Int Ed Engl. 2016 Aug 8;55(33):9620-4. doi: 10.1002/anie.201603328. Epub 2016 Jul 12.

PMID:
27400827
34.

Embryonic Intra-Aortic Clusters Undergo Myeloid Differentiation Mediated by Mesonephros-Derived CSF1 in Mouse.

Sasaki T, Tanaka Y, Kulkeaw K, Yumine-Takai A, Tan KS, Nishinakamura R, Ishida J, Fukamizu A, Sugiyama D.

Stem Cell Rev Rep. 2016 Oct;12(5):530-542.

PMID:
27324145
35.

CTF18 interacts with replication protein A in response to replication stress.

Kaneko Y, Daitoku H, Komeno C, Fukamizu A.

Mol Med Rep. 2016 Jul;14(1):367-72. doi: 10.3892/mmr.2016.5262. Epub 2016 May 13.

PMID:
27175616
36.

NML-mediated rRNA base methylation links ribosomal subunit formation to cell proliferation in a p53-dependent manner.

Waku T, Nakajima Y, Yokoyama W, Nomura N, Kako K, Kobayashi A, Shimizu T, Fukamizu A.

J Cell Sci. 2016 Jun 15;129(12):2382-93. doi: 10.1242/jcs.183723. Epub 2016 May 5.

37.

Lactation Is a Risk Factor of Postpartum Heart Failure in Mice with Cardiomyocyte-specific Apelin Receptor (APJ) Overexpression.

Murata K, Ishida J, Ishimaru T, Mizukami H, Hamada J, Saito C, Fukamizu A.

J Biol Chem. 2016 May 20;291(21):11241-51. doi: 10.1074/jbc.M115.699009. Epub 2016 Mar 31.

38.

Pterosin B has multiple targets in gluconeogenic programs, including coenzyme Q in RORα-SRC2 signaling.

Itoh Y, Fuchino H, Sanosaka M, Kako K, Hada K, Fukamizu A, Takemori H, Kawahara N.

Biochem Biophys Res Commun. 2016 Apr 29;473(2):415-20. doi: 10.1016/j.bbrc.2016.03.016. Epub 2016 Mar 9.

PMID:
26970301
39.

Novel helical assembly in arginine methyltransferase 8.

Toma-Fukai S, Kim JD, Park KE, Kuwabara N, Shimizu N, Krayukhina E, Uchiyama S, Fukamizu A, Shimizu T.

J Mol Biol. 2016 Mar 27;428(6):1197-1208. doi: 10.1016/j.jmb.2016.02.007. Epub 2016 Feb 11.

PMID:
26876602
40.

Ground-based assessment of JAXA mouse habitat cage unit by mouse phenotypic studies.

Shimbo M, Kudo T, Hamada M, Jeon H, Imamura Y, Asano K, Okada R, Tsunakawa Y, Mizuno S, Yagami K, Ishikawa C, Li H, Shiga T, Ishida J, Hamada J, Murata K, Ishimaru T, Hashimoto M, Fukamizu A, Yamane M, Ikawa M, Morita H, Shinohara M, Asahara H, Akiyama T, Akiyama N, Sasanuma H, Yoshida N, Zhou R, Wang YY, Ito T, Kokubu Y, Noguchi TA, Ishimine H, Kurisaki A, Shiba D, Mizuno H, Shirakawa M, Ito N, Takeda S, Takahashi S.

Exp Anim. 2016 May 20;65(2):175-87. doi: 10.1538/expanim.15-0077. Epub 2016 Jan 28.

41.

PRMT8 as a phospholipase regulates Purkinje cell dendritic arborization and motor coordination.

Kim JD, Park KE, Ishida J, Kako K, Hamada J, Kani S, Takeuchi M, Namiki K, Fukui H, Fukuhara S, Hibi M, Kobayashi M, Kanaho Y, Kasuya Y, Mochizuki N, Fukamizu A.

Sci Adv. 2015 Dec 4;1(11):e1500615. doi: 10.1126/sciadv.1500615. eCollection 2015 Dec.

42.

The Drosophila Zinc Finger Transcription Factor Ouija Board Controls Ecdysteroid Biosynthesis through Specific Regulation of spookier.

Komura-Kawa T, Hirota K, Shimada-Niwa Y, Yamauchi R, Shimell M, Shinoda T, Fukamizu A, O'Connor MB, Niwa R.

PLoS Genet. 2015 Dec 10;11(12):e1005712. doi: 10.1371/journal.pgen.1005712. eCollection 2015 Dec.

43.

Severe Hypomyelination and Developmental Defects Are Caused in Mice Lacking Protein Arginine Methyltransferase 1 (PRMT1) in the Central Nervous System.

Hashimoto M, Murata K, Ishida J, Kanou A, Kasuya Y, Fukamizu A.

J Biol Chem. 2016 Jan 29;291(5):2237-45. doi: 10.1074/jbc.M115.684514. Epub 2015 Dec 4.

44.

Detection of ethanolamine altering in fetuses of pregnancy-associated hypertensive mice treated with vasodepressors by using UPLC and MALDI-TOF/MS.

Kako K, Nakamura A, Nagashima Y, Ishida J, Fukamizu A.

J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Dec 1;1006:93-98. doi: 10.1016/j.jchromb.2015.10.018. Epub 2015 Oct 27.

PMID:
26528584
45.

De novo DNA methylation through the 5'-segment of the H19 ICR maintains its imprint during early embryogenesis.

Matsuzaki H, Okamura E, Takahashi T, Ushiki A, Nakamura T, Nakano T, Hata K, Fukamizu A, Tanimoto K.

Development. 2015 Nov 15;142(22):3833-44. doi: 10.1242/dev.126003. Epub 2015 Sep 28.

46.

Angiotensin II accelerates mammary gland development independently of high blood pressure in pregnancy-associated hypertensive mice.

Murata K, Baasanjav A, Kwon C, Hashimoto M, Ishida J, Fukamizu A.

Physiol Rep. 2015 Sep;3(9). pii: e12542. doi: 10.14814/phy2.12542.

47.

Erythropoiesis and Blood Pressure Are Regulated via AT1 Receptor by Distinctive Pathways.

Kato H, Ishida J, Matsusaka T, Ishimaru T, Tanimoto K, Sugiyama F, Yagami K, Nangaku M, Fukamizu A.

PLoS One. 2015 Jun 24;10(6):e0129484. doi: 10.1371/journal.pone.0129484. eCollection 2015.

48.

Podocyte injury-driven lipid peroxidation accelerates the infiltration of glomerular foam cells in focal segmental glomerulosclerosis.

Hara S, Kobayashi N, Sakamoto K, Ueno T, Manabe S, Takashima Y, Hamada J, Pastan I, Fukamizu A, Matsusaka T, Nagata M.

Am J Pathol. 2015 Aug;185(8):2118-31. doi: 10.1016/j.ajpath.2015.04.007. Epub 2015 Jun 11.

49.

APJ Regulates Parallel Alignment of Arteries and Veins in the Skin.

Kidoya H, Naito H, Muramatsu F, Yamakawa D, Jia W, Ikawa M, Sonobe T, Tsuchimochi H, Shirai M, Adams RH, Fukamizu A, Takakura N.

Dev Cell. 2015 May 4;33(3):247-59. doi: 10.1016/j.devcel.2015.02.024. Epub 2015 Apr 23.

50.

Possible involvement of downregulation of the apelin-APJ system in doxorubicin-induced cardiotoxicity.

Hamada J, Baasanjav A, Ono N, Murata K, Kako K, Ishida J, Fukamizu A.

Am J Physiol Heart Circ Physiol. 2015 Apr 15;308(8):H931-41. doi: 10.1152/ajpheart.00703.2013. Epub 2015 Feb 13.

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