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Items: 1 to 50 of 517

1.

Design and Discovery of an Orally Efficacious Spiroindolinone-Based Tankyrase Inhibitor for the Treatment of Colon Cancer.

Shirai F, Mizutani A, Yashiroda Y, Tsumura T, Kano Y, Muramatsu Y, Chikada T, Yuki H, Niwa H, Sato S, Washizuka K, Koda Y, Mazaki Y, Jang MK, Yoshida H, Nagamori A, Okue M, Watanabe T, Kitamura K, Shitara E, Honma T, Umehara T, Shirouzu M, Fukami T, Seimiya H, Yoshida M, Koyama H.

J Med Chem. 2020 Apr 1. doi: 10.1021/acs.jmedchem.0c00045. [Epub ahead of print]

PMID:
32202790
2.

Intensive farming drives long-term shifts in avian community composition.

Hendershot JN, Smith JR, Anderson CB, Letten AD, Frishkoff LO, Zook JR, Fukami T, Daily GC.

Nature. 2020 Mar;579(7799):393-396. doi: 10.1038/s41586-020-2090-6. Epub 2020 Mar 18.

PMID:
32188954
3.

SLC35B1 significantly contributes to the uptake of UDPGA into the endoplasmic reticulum for glucuronidation catalyzed by UDP-glucuronosyltransferases.

Ondo K, Arakawa H, Nakano M, Fukami T, Nakajima M.

Biochem Pharmacol. 2020 Mar 14;175:113916. doi: 10.1016/j.bcp.2020.113916. [Epub ahead of print]

PMID:
32179043
4.

Pulmonary resection for nontuberculous mycobacterial pulmonary disease: outcomes and risk factors for recurrence.

Yotsumoto T, Inoue Y, Fukami T, Matsui H.

Gen Thorac Cardiovasc Surg. 2020 Mar 7. doi: 10.1007/s11748-020-01326-1. [Epub ahead of print]

PMID:
32146579
5.

A Novel Systematic Approach for Selection of Prodrugs Designed to Improve Oral Absorption.

Shimizu M, Fukami T, Taniguchi T, Nomura Y, Nakajima M.

J Pharm Sci. 2020 Feb 4. pii: S0022-3549(20)30068-X. doi: 10.1016/j.xphs.2020.01.028. [Epub ahead of print]

PMID:
32027923
6.

Comparison of various pharmaceutical properties of clobetasol propionate cream formulations - considering stability of mixture with moisturizer.

Yamamoto Y, Onuki Y, Fukami T, Koide T.

J Pharm Health Care Sci. 2020 Jan 30;6:1. doi: 10.1186/s40780-020-0158-y. eCollection 2020.

7.

Determining the Distribution of Active Pharmaceutical Ingredients in Combination Tablets Using Near IR and Low-Frequency Raman Spectroscopy Imaging.

Hisada H, Okayama A, Hoshino T, Carriere J, Koide T, Yamamoto Y, Fukami T.

Chem Pharm Bull (Tokyo). 2020;68(2):155-160. doi: 10.1248/cpb.c19-00791.

8.

In situ monitoring of the crystalline state of active pharmaceutical ingredients during high-shear wet granulation using a low-frequency Raman probe.

Nomura K, Titapiwatanakun V, Hisada H, Koide T, Fukami T.

Eur J Pharm Biopharm. 2020 Feb;147:1-9. doi: 10.1016/j.ejpb.2019.12.004. Epub 2019 Dec 10.

PMID:
31841690
9.

Potential application of novel liquid crystal nanoparticles of isostearyl glyceryl ether for transdermal delivery of 4-biphenyl acetic acid.

Fujii MY, Asakawa Y, Fukami T.

Int J Pharm. 2020 Feb 15;575:118935. doi: 10.1016/j.ijpharm.2019.118935. Epub 2019 Dec 6.

PMID:
31816353
10.
11.

Recent trends in the incidence of latent tuberculosis infection in Japanese patients with lung cancer: A small retrospective study.

Tamura A, Fukami T, Hebisawa A, Takahashi F.

J Infect Chemother. 2020 Mar;26(3):315-317. doi: 10.1016/j.jiac.2019.10.018. Epub 2019 Nov 29.

12.

Identification of small molecule inhibitors of human COQ7.

Tsuganezawa K, Sekimata K, Nakagawa Y, Utata R, Nakamura K, Ogawa N, Koyama H, Shirouzu M, Fukami T, Kita K, Tanaka A.

Bioorg Med Chem. 2020 Jan 1;28(1):115182. doi: 10.1016/j.bmc.2019.115182. Epub 2019 Nov 9.

PMID:
31753803
13.

Secretary's Report, 2019: American Society of Naturalists.

Fukami T.

Am Nat. 2019 Dec;194(6):876-878. doi: 10.1086/706140. Epub 2019 Oct 24. No abstract available.

PMID:
31738094
14.

Strain and sex differences in drug hydrolase activities in rodent livers.

Kisui F, Fukami T, Nakano M, Nakajima M.

Eur J Pharm Sci. 2020 Jan 15;142:105143. doi: 10.1016/j.ejps.2019.105143. Epub 2019 Nov 11.

PMID:
31726091
15.

Methylation of adenosine at the N6 position post-transcriptionally regulates hepatic P450s expression.

Nakano M, Ondo K, Takemoto S, Fukami T, Nakajima M.

Biochem Pharmacol. 2020 Jan;171:113697. doi: 10.1016/j.bcp.2019.113697. Epub 2019 Nov 7.

PMID:
31706844
16.

Land-use change has host-specific influences on avian gut microbiomes.

San Juan PA, Hendershot JN, Daily GC, Fukami T.

ISME J. 2020 Jan;14(1):318-321. doi: 10.1038/s41396-019-0535-4. Epub 2019 Oct 17.

PMID:
31624349
17.

Sexual Dimorphism and Species Diversity: from Clades to Sites.

Tsuji K, Fukami T.

Trends Ecol Evol. 2020 Feb;35(2):105-114. doi: 10.1016/j.tree.2019.09.001. Epub 2019 Oct 14. Review.

PMID:
31623865
18.

Solid-State Quantification of Cocrystals in Pharmaceutical Tablets Using Transmission Low-Frequency Raman Spectroscopy.

Inoue M, Osada T, Hisada H, Koide T, Fukami T, Roy A, Carriere J, Heyler R.

Anal Chem. 2019 Nov 5;91(21):13427-13432. doi: 10.1021/acs.analchem.9b01895. Epub 2019 Oct 10.

PMID:
31565923
19.

Quantification of a cocrystal and its dissociated compounds in solid dosage form using transmission Raman spectroscopy.

Koide T, Takeuchi Y, Otaki T, Yamamoto K, Shimamura R, Ohashi R, Inoue M, Fukami T, Izutsu KI.

J Pharm Biomed Anal. 2020 Jan 5;177:112886. doi: 10.1016/j.jpba.2019.112886. Epub 2019 Sep 18.

PMID:
31563757
20.

Improving the Solid-State Photostability of Furosemide by Its Cocrystal Formation.

Teraoka R, Fukami T, Furuishi T, Nagase H, Ueda H, Tode C, Yutani R, Kitagawa S, Sakane T.

Chem Pharm Bull (Tokyo). 2019;67(9):940-944. doi: 10.1248/cpb.c18-00812.

21.

Measurement of the Water Content in Semi-solid Formulations Used to Treat Pressure Ulcers and Evaluation of Their Water Absorption Characteristics.

Hoshino T, Azuma M, Yamada Y, Titapiwatanakun V, Yoshimura Fujii M, Yamamoto Y, Koide T, Fukami T.

Chem Pharm Bull (Tokyo). 2019;67(9):929-934. doi: 10.1248/cpb.c18-00746.

22.

Species identification, antifungal susceptibility, and clinical feature association of Aspergillus section Nigri isolates from the lower respiratory tract.

Takeda K, Suzuki J, Watanabe A, Matsuki M, Higa K, Inoue E, Akashi S, Shimada M, Kawashima M, Ohshima N, Fukami T, Masuda K, Yamane A, Tamura A, Nagai H, Matsui H, Tohma S, Kamei K.

Med Mycol. 2020 Apr 1;58(3):E3. doi: 10.1093/mmy/myz085. No abstract available.

PMID:
31384931
23.

Imaging Analysis Enables Differentiation of the Distribution of Pharmaceutical Ingredients in Tacrolimus Ointments.

Fujii MY, Yamamoto Y, Koide T, Hamaguchi M, Onuki Y, Suzuki N, Suzuki T, Fukami T.

Appl Spectrosc. 2019 Oct;73(10):1183-1192. doi: 10.1177/0003702819863441. Epub 2019 Jul 30.

PMID:
31271295
24.

Adenosine Deaminases Acting on RNA Downregulate the Expression of Constitutive Androstane Receptor in the Human Liver-Derived Cells by Attenuating Splicing.

Nakano M, Fukami T, Nakajima M.

J Pharmacol Exp Ther. 2019 Sep;370(3):408-415. doi: 10.1124/jpet.119.260109. Epub 2019 Jul 3.

PMID:
31270214
25.

Characterization of human UGT2A3 expression using a prepared specific antibody against UGT2A3.

Gotoh-Saito S, Abe T, Furukawa Y, Oda S, Yokoi T, Finel M, Hatakeyama M, Fukami T, Nakajima M.

Drug Metab Pharmacokinet. 2019 Aug;34(4):280-286. doi: 10.1016/j.dmpk.2019.05.001. Epub 2019 May 13.

PMID:
31262603
26.

Species identification, antifungal susceptibility, and clinical feature association of Aspergillus section Nigri isolates from the lower respiratory tract.

Takeda K, Suzuki J, Watanabe A, Matsuki M, Higa K, Inoue E, Akashi S, Shimada M, Kawashima M, Ohshima N, Fukami T, Masuda K, Yamane A, Tamura A, Nagai H, Matsui H, Tohma S, Kamei K.

Med Mycol. 2020 Apr 1;58(3):310-314. doi: 10.1093/mmy/myz072.

PMID:
31240316
27.

Exploring Novel Cocrystalline Forms of Oxyresveratrol to Enhance Aqueous Solubility and Permeability across a Cell Monolayer.

Suzuki Y, Muangnoi C, Thaweesest W, Teerawonganan P, Ratnatilaka Na Bhuket P, Titapiwatanakun V, Yoshimura-Fujii M, Sritularak B, Likhitwitayawuid K, Rojsitthisak P, Fukami T.

Biol Pharm Bull. 2019;42(6):1004-1012. doi: 10.1248/bpb.b19-00048.

28.

Pharmaceutical quantification with univariate analysis using transmission Raman spectroscopy.

Shimamura R, Koide T, Hisada H, Inoue M, Fukami T, Katori N, Goda Y.

Drug Dev Ind Pharm. 2019 Sep;45(9):1430-1436. doi: 10.1080/03639045.2019.1621336. Epub 2019 Jun 4.

PMID:
31104513
29.

High-resolution mapping reveals that microniches in the gastric glands control Helicobacter pylori colonization of the stomach.

Fung C, Tan S, Nakajima M, Skoog EC, Camarillo-Guerrero LF, Klein JA, Lawley TD, Solnick JV, Fukami T, Amieva MR.

PLoS Biol. 2019 May 2;17(5):e3000231. doi: 10.1371/journal.pbio.3000231. eCollection 2019 May.

30.

RNA Editing Enzymes Modulate the Expression of Hepatic CYP2B6, CYP2C8, and Other Cytochrome P450 Isoforms.

Nozaki K, Nakano M, Iwakami C, Fukami T, Nakajima M.

Drug Metab Dispos. 2019 Jun;47(6):639-647. doi: 10.1124/dmd.119.086702. Epub 2019 Apr 15. Erratum in: Drug Metab Dispos. 2019 Jul;47(7):753-755.

PMID:
30988053
31.

Competing Risk Analysis in Lung Cancer Patients Over 80 Years Old Undergoing Surgery.

Hino H, Karasaki T, Yoshida Y, Fukami T, Sano A, Tanaka M, Furuhata Y, Kashiwabara K, Ichinose J, Kawashima M, Nakajima J.

World J Surg. 2019 Jul;43(7):1857-1866. doi: 10.1007/s00268-019-04982-4.

PMID:
30937488
32.

Discovery of Novel Spiroindoline Derivatives as Selective Tankyrase Inhibitors.

Shirai F, Tsumura T, Yashiroda Y, Yuki H, Niwa H, Sato S, Chikada T, Koda Y, Washizuka K, Yoshimoto N, Abe M, Onuki T, Mazaki Y, Hirama C, Fukami T, Watanabe H, Honma T, Umehara T, Shirouzu M, Okue M, Kano Y, Watanabe T, Kitamura K, Shitara E, Muramatsu Y, Yoshida H, Mizutani A, Seimiya H, Yoshida M, Koyama H.

J Med Chem. 2019 Apr 11;62(7):3407-3427. doi: 10.1021/acs.jmedchem.8b01888. Epub 2019 Apr 1.

PMID:
30883102
33.

Applying modern coexistence theory to priority effects.

Grainger TN, Letten AD, Gilbert B, Fukami T.

Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6205-6210. doi: 10.1073/pnas.1803122116. Epub 2019 Mar 8.

34.

Yeast-Bacterium Interactions: The Next Frontier in Nectar Research.

Álvarez-Pérez S, Lievens B, Fukami T.

Trends Plant Sci. 2019 May;24(5):393-401. doi: 10.1016/j.tplants.2019.01.012. Epub 2019 Feb 18. Review.

PMID:
30792076
35.

[Optimum Volume of Water Needed for the Paste State of Pediatric Powders: Considerations Based on Yield Values and Applications to Generic Medicine].

Fukuda H, Suzuki T, Hashizaki K, Yoshimura S, Kobayashi C, Omotani Y, Suzuki N, Kanazawa T, Fukami T, Yamamoto Y.

Yakugaku Zasshi. 2019;139(2):299-308. doi: 10.1248/yakushi.18-00182. Japanese.

36.

Screening a trace amount of pharmaceutical cocrystals by using an enhanced nano-spot method.

Tanabe Y, Maeno Y, Ohashi K, Hisada H, Roy A, Carriere J, Heyler R, Fukami T.

Eur J Pharm Biopharm. 2019 Mar;136:131-137. doi: 10.1016/j.ejpb.2019.01.018. Epub 2019 Jan 17.

PMID:
30660695
37.

Incidence and risk factors for postpartum hemorrhage among transvaginal deliveries at a tertiary perinatal medical facility in Japan.

Fukami T, Koga H, Goto M, Ando M, Matsuoka S, Tohyama A, Yamamoto H, Nakamura S, Koyanagi T, To Y, Kondo H, Eguchi F, Tsujioka H.

PLoS One. 2019 Jan 9;14(1):e0208873. doi: 10.1371/journal.pone.0208873. eCollection 2019.

38.

Transmission Low-Frequency Raman Spectroscopy for Quantification of Crystalline Polymorphs in Pharmaceutical Tablets.

Inoue M, Hisada H, Koide T, Fukami T, Roy A, Carriere J, Heyler R.

Anal Chem. 2019 Feb 5;91(3):1997-2003. doi: 10.1021/acs.analchem.8b04365. Epub 2019 Jan 15.

PMID:
30606009
39.

Role of Farnesoid X Receptor and Bile Acids in Hepatic Tumor Development.

Takahashi S, Tanaka N, Fukami T, Xie C, Yagai T, Kim D, Velenosi TJ, Yan T, Krausz KW, Levi M, Gonzalez FJ.

Hepatol Commun. 2018 Oct 1;2(12):1567-1582. doi: 10.1002/hep4.1263. eCollection 2018 Dec.

40.

Corrigendum to 'Intraventricular Epithelioid Glioblastoma: A Case Report' [World Neurosurgery 112 (2018) 257-263].

Nitta N, Moritani S, Fukami T, Yoshimura Y, Hirai H, Nozaki K.

World Neurosurg. 2019 Feb;122:727. doi: 10.1016/j.wneu.2018.11.219. Epub 2018 Dec 11. No abstract available.

PMID:
30551971
41.

Quantitative Analysis of UDP-Glucuronosyltransferase Ugt1a and Ugt2b mRNA Expression in the Rat Liver and Small Intestine: Sex and Strain Differences.

Kutsukake T, Furukawa Y, Ondo K, Gotoh S, Fukami T, Nakajima M.

Drug Metab Dispos. 2019 Jan;47(1):38-44. doi: 10.1124/dmd.118.083287. Epub 2018 Nov 2.

PMID:
30389729
42.

Substrate selectivity of human aldehyde oxidase 1 in reduction of nitroaromatic drugs.

Ogiso T, Fukami T, Mishiro K, Konishi K, Jones JP, Nakajima M.

Arch Biochem Biophys. 2018 Dec 1;659:85-92. doi: 10.1016/j.abb.2018.10.017. Epub 2018 Oct 25.

PMID:
30367827
43.

Efficacy of Hormonal Therapies for Decreasing Uterine Volume in Patients with Adenomyosis.

Matsushima T, Akira S, Fukami T, Yoneyama K, Takeshita T.

Gynecol Minim Invasive Ther. 2018 Jul-Sep;7(3):119-123. doi: 10.4103/GMIT.GMIT_35_18. Epub 2018 Aug 23.

44.

Vertical foraging shifts in Hawaiian forest birds in response to invasive rat removal.

Wilson Rankin EE, Knowlton JL, Gruner DS, Flaspohler DJ, Giardina CP, Leopold DR, Buckardt A, Pitt WC, Fukami T.

PLoS One. 2018 Sep 24;13(9):e0202869. doi: 10.1371/journal.pone.0202869. eCollection 2018.

45.

RK-287107, a potent and specific tankyrase inhibitor, blocks colorectal cancer cell growth in a preclinical model.

Mizutani A, Yashiroda Y, Muramatsu Y, Yoshida H, Chikada T, Tsumura T, Okue M, Shirai F, Fukami T, Yoshida M, Seimiya H.

Cancer Sci. 2018 Dec;109(12):4003-4014. doi: 10.1111/cas.13805. Epub 2018 Oct 20.

46.

Community-wide consequences of sexual dimorphism: evidence from nectar microbes in dioecious plants.

Tsuji K, Fukami T.

Ecology. 2018 Nov;99(11):2476-2484. doi: 10.1002/ecy.2494. Epub 2018 Sep 14.

PMID:
30216955
47.

Isolation and characterization of an aspartic protease able to hydrolyze and decolorize heme proteins from Aspergillus glaucus.

Takenaka S, Lim L, Fukami T, Yokota S, Doi M.

J Sci Food Agric. 2019 Mar 15;99(4):2042-2047. doi: 10.1002/jsfa.9339. Epub 2018 Oct 9.

PMID:
30187473
48.

Molecular State of Active Pharmaceutical Ingredients in Ketoprofen Dermal Patches Characterized by Pharmaceutical Evaluation.

Azuma M, Fujii M, Inoue M, Hisada H, Koide T, Kemper M, Yamamoto Y, Suzuki N, Suzuki T, Fukami T.

Biol Pharm Bull. 2018;41(9):1348-1354. doi: 10.1248/bpb.b18-00019.

49.

Mixtures of betamethasone butyrate propionate ointments and heparinoid oil-based cream: Physical stability evaluation.

Yamamoto Y, Hanai A, Onuki Y, Fujii M, Onishi Y, Fukami T, Metori K, Suzuki N, Suzuki T, Koide T.

Eur J Pharm Sci. 2018 Nov 1;124:199-207. doi: 10.1016/j.ejps.2018.08.040. Epub 2018 Aug 29.

PMID:
30171983
50.

The presence of amniotic fluid sludge in pregnant women with a short cervix: an independent risk of preterm delivery.

Tsunoda Y, Fukami T, Yoneyama K, Kawabata I, Takeshita T.

J Matern Fetal Neonatal Med. 2020 Mar;33(6):920-923. doi: 10.1080/14767058.2018.1509309. Epub 2018 Sep 19.

PMID:
30081692

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