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Neuronal stability in medial frontal cortex sets individual variability in decision-making.

Kurikawa T, Haga T, Handa T, Harukuni R, Fukai T.

Nat Neurosci. 2018 Dec;21(12):1764-1773. doi: 10.1038/s41593-018-0263-5. Epub 2018 Nov 12.


PRKAA1/AMPKα1-driven glycolysis in endothelial cells exposed to disturbed flow protects against atherosclerosis.

Yang Q, Xu J, Ma Q, Liu Z, Sudhahar V, Cao Y, Wang L, Zeng X, Zhou Y, Zhang M, Xu Y, Wang Y, Weintraub NL, Zhang C, Fukai T, Wu C, Huang L, Han Z, Wang T, Fulton DJ, Hong M, Huo Y.

Nat Commun. 2018 Nov 7;9(1):4667. doi: 10.1038/s41467-018-07132-x.


Dendritic processing of spontaneous neuronal sequences for single-trial learning.

Haga T, Fukai T.

Sci Rep. 2018 Oct 11;8(1):15166. doi: 10.1038/s41598-018-33513-9.


Interactive reservoir computing for chunking information streams.

Asabuki T, Hiratani N, Fukai T.

PLoS Comput Biol. 2018 Oct 8;14(10):e1006400. doi: 10.1371/journal.pcbi.1006400. eCollection 2018 Oct.


Copper Transporter ATP7A Interacts with IQGAP1, a Rac1 Binding Scaffold Protein: Role in PDGF-induced VSMC Migration and Vascular Remodeling.

Ashino T, Kohno T, Sudhahar V, Ash D, Ushio-Fukai M, Fukai T.

Am J Physiol Cell Physiol. 2018 Sep 26. doi: 10.1152/ajpcell.00230.2018. [Epub ahead of print]


Oxidant Signaling Mediated by Nox2 in Neutrophils Promotes Regenerative Myelopoiesis and Tissue Recovery following Ischemic Damage.

Fang MM, Barman PK, Thiruppathi M, Mirza RE, McKinney RD, Deng J, Christman JW, Du X, Fukai T, Ennis WJ, Koh TJ, Ushio-Fukai M, Urao N.

J Immunol. 2018 Oct 15;201(8):2414-2426. doi: 10.4049/jimmunol.1800252. Epub 2018 Sep 10.


Transient and Persistent UP States during Slow-wave Oscillation and their Implications for Cell-Assembly Dynamics.

Fung CCA, Fukai T.

Sci Rep. 2018 Jul 16;8(1):10680. doi: 10.1038/s41598-018-28973-y.


Learning Task-Related Activities From Independent Local-Field-Potential Components Across Motor Cortex Layers.

Martín-Vázquez G, Asabuki T, Isomura Y, Fukai T.

Front Neurosci. 2018 Jun 26;12:429. doi: 10.3389/fnins.2018.00429. eCollection 2018.


Recurrent network model for learning goal-directed sequences through reverse replay.

Haga T, Fukai T.

Elife. 2018 Jul 3;7. pii: e34171. doi: 10.7554/eLife.34171.


Redundancy in synaptic connections enables neurons to learn optimally.

Hiratani N, Fukai T.

Proc Natl Acad Sci U S A. 2018 Jul 17;115(29):E6871-E6879. doi: 10.1073/pnas.1803274115. Epub 2018 Jul 2.


Redox Regulation of Mitochondrial Fission Protein Drp1 by Protein Disulfide Isomerase Limits Endothelial Senescence.

Kim YM, Youn SW, Sudhahar V, Das A, Chandhri R, Cuervo Grajal H, Kweon J, Leanhart S, He L, Toth PT, Kitajewski J, Rehman J, Yoon Y, Cho J, Fukai T, Ushio-Fukai M.

Cell Rep. 2018 Jun 19;23(12):3565-3578. doi: 10.1016/j.celrep.2018.05.054.


Copper transporters and copper chaperones: roles in cardiovascular physiology and disease.

Fukai T, Ushio-Fukai M, Kaplan JH.

Am J Physiol Cell Physiol. 2018 Aug 1;315(2):C186-C201. doi: 10.1152/ajpcell.00132.2018. Epub 2018 Jun 6.


Phase Behavior of Co-Nonsolvent Systems: Poly( N-isopropylacrylamide) in Mixed Solvents of Water and Methanol.

Fukai T, Shinyashiki N, Yagihara S, Kita R, Tanaka F.

Langmuir. 2018 Mar 6;34(9):3003-3009. doi: 10.1021/acs.langmuir.7b03815. Epub 2018 Feb 20.


Akt2 (Protein Kinase B Beta) Stabilizes ATP7A, a Copper Transporter for Extracellular Superoxide Dismutase, in Vascular Smooth Muscle: Novel Mechanism to Limit Endothelial Dysfunction in Type 2 Diabetes Mellitus.

Sudhahar V, Okur MN, Bagi Z, O'Bryan JP, Hay N, Makino A, Patel VS, Phillips SA, Stepp D, Ushio-Fukai M, Fukai T.

Arterioscler Thromb Vasc Biol. 2018 Mar;38(3):529-541. doi: 10.1161/ATVBAHA.117.309819. Epub 2018 Jan 4.


Detailed Dendritic Excitatory/Inhibitory Balance through Heterosynaptic Spike-Timing-Dependent Plasticity.

Hiratani N, Fukai T.

J Neurosci. 2017 Dec 13;37(50):12106-12122. doi: 10.1523/JNEUROSCI.0027-17.2017. Epub 2017 Oct 31.


Adipose-derived stem cells express higher levels of type VII collagen under specific culture conditions.

Maeda Y, Hasegawa T, Wada A, Fukai T, Iida H, Sakamoto A, Ikeda S.

Arch Dermatol Res. 2017 Dec;309(10):843-849. doi: 10.1007/s00403-017-1781-9. Epub 2017 Sep 22.


ROS-induced ROS release orchestrated by Nox4, Nox2, and mitochondria in VEGF signaling and angiogenesis.

Kim YM, Kim SJ, Tatsunami R, Yamamura H, Fukai T, Ushio-Fukai M.

Am J Physiol Cell Physiol. 2017 Jun 1;312(6):C749-C764. doi: 10.1152/ajpcell.00346.2016. Epub 2017 Apr 19.


Short-term regular aerobic exercise reduces oxidative stress produced by acute in the adipose microvasculature.

Robinson AT, Fancher IS, Sudhahar V, Bian JT, Cook MD, Mahmoud AM, Ali MM, Ushio-Fukai M, Brown MD, Fukai T, Phillips SA.

Am J Physiol Heart Circ Physiol. 2017 May 1;312(5):H896-H906. doi: 10.1152/ajpheart.00684.2016. Epub 2017 Feb 24.


Medial Frontal Circuit Dynamics Represents Probabilistic Choices for Unfamiliar Sensory Experience.

Handa T, Takekawa T, Harukuni R, Isomura Y, Fukai T.

Cereb Cortex. 2017 Jul 1;27(7):3818-3831. doi: 10.1093/cercor/bhx031.


Endothelial Antioxidant-1: a Key Mediator of Copper-dependent Wound Healing in vivo.

Das A, Sudhahar V, Chen GF, Kim HW, Youn SW, Finney L, Vogt S, Yang J, Kweon J, Surenkhuu B, Ushio-Fukai M, Fukai T.

Sci Rep. 2016 Sep 26;6:33783. doi: 10.1038/srep33783.


Mouse Specific Cleavage-Resistant RAGE Splice Variant.

Fukai T.

PLoS One. 2016 Sep 21;11(9):e0162120. doi: 10.1371/journal.pone.0162120. eCollection 2016. No abstract available.


Hebbian Wiring Plasticity Generates Efficient Network Structures for Robust Inference with Synaptic Weight Plasticity.

Hiratani N, Fukai T.

Front Neural Circuits. 2016 May 31;10:41. doi: 10.3389/fncir.2016.00041. eCollection 2016.


Top-down cortical input during NREM sleep consolidates perceptual memory.

Miyamoto D, Hirai D, Fung CC, Inutsuka A, Odagawa M, Suzuki T, Boehringer R, Adaikkan C, Matsubara C, Matsuki N, Fukai T, McHugh TJ, Yamanaka A, Murayama M.

Science. 2016 Jun 10;352(6291):1315-8. doi: 10.1126/science.aaf0902. Epub 2016 May 26.


[Determination of the Plant Origin of Licorice Oil Extract, a Natural Food Additive, by Principal Component Analysis Based on Chemical Components].

Tada A, Ishizuki K, Sugimoto N, Yoshimatsu K, Kawahara N, Suematsu T, Arifuku K, Fukai T, Tamura Y, Ohtsuki T, Tahara M, Yamazaki T, Akiyama H.

Shokuhin Eiseigaku Zasshi. 2015;56(5):217-27. doi: 10.3358/shokueishi.56.217. Japanese.


A Lognormal Recurrent Network Model for Burst Generation during Hippocampal Sharp Waves.

Omura Y, Carvalho MM, Inokuchi K, Fukai T.

J Neurosci. 2015 Oct 28;35(43):14585-601. doi: 10.1523/JNEUROSCI.4944-14.2015.


Renin-Angiotensin Activation and Oxidative Stress in Early Heart Failure with Preserved Ejection Fraction.

Negi SI, Jeong EM, Shukrullah I, Veleder E, Jones DP, Fan TH, Varadarajan S, Danilov SM, Fukai T, Dudley SC Jr.

Biomed Res Int. 2015;2015:825027. doi: 10.1155/2015/825027. Epub 2015 Oct 4.


Copper Transport Protein Antioxidant-1 Promotes Inflammatory Neovascularization via Chaperone and Transcription Factor Function.

Chen GF, Sudhahar V, Youn SW, Das A, Cho J, Kamiya T, Urao N, McKinney RD, Surenkhuu B, Hamakubo T, Iwanari H, Li S, Christman JW, Shantikumar S, Angelini GD, Emanueli C, Ushio-Fukai M, Fukai T.

Sci Rep. 2015 Oct 6;5:14780. doi: 10.1038/srep14780.


Two new isoflavanones from the roots of Erythrina variegata.

Tanaka H, Atsumi I, Hasegawa M, Hirata M, Sakai T, Sato M, Yamaguchi R, Tateishi Y, Tanaka T, Fukai T.

Nat Prod Commun. 2015 Mar;10(3):499-501.


Mixed signal learning by spike correlation propagation in feedback inhibitory circuits.

Hiratani N, Fukai T.

PLoS Comput Biol. 2015 Apr 24;11(4):e1004227. doi: 10.1371/journal.pcbi.1004227. eCollection 2015 Apr.


TLR4 is a critical regulator of angiotensin II-induced vascular remodeling: the roles of extracellular SOD and NADPH oxidase.

Nakashima T, Umemoto S, Yoshimura K, Matsuda S, Itoh S, Murata T, Fukai T, Matsuzaki M.

Hypertens Res. 2015 Oct;38(10):649-55. doi: 10.1038/hr.2015.55. Epub 2015 Apr 9.


Cutaneous sparganosis: a rare parasitic infection.

Johnson G, Gardner J, Fukai T, Goto K.

J Cutan Pathol. 2015 Mar;42(3):159-63. doi: 10.1111/cup.12480. No abstract available.


Angiotensin Ⅱ Activates MCP-1 and Induces Cardiac Hypertrophy and Dysfunction via Toll-like Receptor 4.

Matsuda S, Umemoto S, Yoshimura K, Itoh S, Murata T, Fukai T, Matsuzaki M.

J Atheroscler Thromb. 2015 Aug 26;22(8):833-44. doi: 10.5551/jat.27292. Epub 2015 Mar 5.


Keratinocyte progenitor cells reside in human subcutaneous adipose tissue.

Hasegawa T, Sakamoto A, Wada A, Fukai T, Iida H, Ikeda S.

PLoS One. 2015 Feb 25;10(2):e0118402. doi: 10.1371/journal.pone.0118402. eCollection 2015.


Cutaneous sparganosis: a rare parasitic infection.

Johnson G, Gardner J, Fukai T, Goto K.

J Cutan Pathol. 2015 Jan;42(1):1-5. doi: 10.1111/cup.12463. No abstract available.


The habenulo-raphe serotonergic circuit encodes an aversive expectation value essential for adaptive active avoidance of danger.

Amo R, Fredes F, Kinoshita M, Aoki R, Aizawa H, Agetsuma M, Aoki T, Shiraki T, Kakinuma H, Matsuda M, Yamazaki M, Takahoko M, Tsuboi T, Higashijima S, Miyasaka N, Koide T, Yabuki Y, Yoshihara Y, Fukai T, Okamoto H.

Neuron. 2014 Dec 3;84(5):1034-48. doi: 10.1016/j.neuron.2014.10.035. Epub 2014 Nov 20.


Spiking network simulation code for petascale computers.

Kunkel S, Schmidt M, Eppler JM, Plesser HE, Masumoto G, Igarashi J, Ishii S, Fukai T, Morrison A, Diesmann M, Helias M.

Front Neuroinform. 2014 Oct 10;8:78. doi: 10.3389/fninf.2014.00078. eCollection 2014.


Nitroglycerin tolerance in caveolin-1 deficient mice.

Mao M, Varadarajan S, Fukai T, Bakhshi FR, Chernaya O, Dudley SC Jr, Minshall RD, Bonini MG.

PLoS One. 2014 Aug 26;9(8):e104101. doi: 10.1371/journal.pone.0104101. eCollection 2014.


Interplay between short- and long-term plasticity in cell-assembly formation.

Hiratani N, Fukai T.

PLoS One. 2014 Jul 9;9(7):e101535. doi: 10.1371/journal.pone.0101535. eCollection 2014.


Excitatory and inhibitory STDP jointly tune feedforward neural circuits to selectively propagate correlated spiking activity.

Kleberg FI, Fukai T, Gilson M.

Front Comput Neurosci. 2014 May 7;8:53. doi: 10.3389/fncom.2014.00053. eCollection 2014.


Spike detection from noisy neural data in linear-probe recordings.

Takekawa T, Ota K, Murayama M, Fukai T.

Eur J Neurosci. 2014 Jun;39(11):1943-50. doi: 10.1111/ejn.12614. Epub 2014 May 15.


A retrospective study of 231 Japanese vitiligo patients with special reference to phototherapy.

Yoshida A, Takagi A, Ikejima A, Takenaka H, Fukai T, Ikeda S.

Acta Dermatovenerol Croat. 2014;22(1):13-8.


Case of erlotinib-induced photosensitivity.

Fukai T, Hasegawa T, Nagata A, Matsumura M, Kudo Y, Shiraishi E, Kamiya Y, Hirasawa Y, Ikeda S.

J Dermatol. 2014 May;41(5):445-6. doi: 10.1111/1346-8138.12476. No abstract available.


Dense neuron clustering explains connectivity statistics in cortical microcircuits.

Klinshov VV, Teramae JN, Nekorkin VI, Fukai T.

PLoS One. 2014 Apr 14;9(4):e94292. doi: 10.1371/journal.pone.0094292. eCollection 2014.


Solubility of poly(methyl methacrylate) in ionic liquids in relation to solvent parameters.

Ueno K, Fukai T, Nagatsuka T, Yasuda T, Watanabe M.

Langmuir. 2014 Mar 25;30(11):3228-35. doi: 10.1021/la404797g. Epub 2014 Mar 11.


Low-dose 6-bromoindirubin-3'-oxime induces partial dedifferentiation of endothelial cells to promote increased neovascularization.

Kohler EE, Baruah J, Urao N, Ushio-Fukai M, Fukai T, Chatterjee I, Wary KK.

Stem Cells. 2014 Jun;32(6):1538-52. doi: 10.1002/stem.1658.


Improvement of red color development on the surface of kuruma prawn Marsupenaeus japonicus under various conditions.

Ando M, Fukai T, Kawasaki K, Itoh T, Tsukamasa Y.

J Food Sci. 2014 Feb;79(2):E202-7. doi: 10.1111/1750-3841.12353. Epub 2014 Jan 23.


Spatial and feature-based attention in a layered cortical microcircuit model.

Wagatsuma N, Potjans TC, Diesmann M, Sakai K, Fukai T.

PLoS One. 2013 Dec 6;8(12):e80788. doi: 10.1371/journal.pone.0080788. eCollection 2013.


A θ-γ oscillation code for neuronal coordination during motor behavior.

Igarashi J, Isomura Y, Arai K, Harukuni R, Fukai T.

J Neurosci. 2013 Nov 20;33(47):18515-30. doi: 10.1523/JNEUROSCI.2126-13.2013.


A case of phaeohyphomycosis caused by Exophiala oligosperma successfully treated with local hyperthermia.

Fukai T, Hiruma M, Ogawa Y, Ikeda S, Ikeda H, Sano A, Makimura K.

Med Mycol J. 2013;54(3):297-301.


Copper transporter ATP7A protects against endothelial dysfunction in type 1 diabetic mice by regulating extracellular superoxide dismutase.

Sudhahar V, Urao N, Oshikawa J, McKinney RD, Llanos RM, Mercer JF, Ushio-Fukai M, Fukai T.

Diabetes. 2013 Nov;62(11):3839-50. doi: 10.2337/db12-1228. Epub 2013 Jul 24.

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