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Items: 1 to 50 of 90

1.

Plasmacytoid dendritic cell dysfunction caused by heat stress is improved by administration of Lactococcus lactis strain plasma in mice.

Sugimura T, Jounai K, Ohshio K, Fujiwara D.

Biosci Biotechnol Biochem. 2019 Jul 18:1-4. doi: 10.1080/09168451.2019.1642098. [Epub ahead of print]

PMID:
31318317
2.

SIRT1 deficiency interferes with membrane resealing after cell membrane injury.

Fujiwara D, Iwahara N, Sebori R, Hosoda R, Shimohama S, Kuno A, Horio Y.

PLoS One. 2019 Jun 26;14(6):e0218329. doi: 10.1371/journal.pone.0218329. eCollection 2019.

3.

Characterization of genomic DNA of lactic acid bacteria for activation of plasmacytoid dendritic cells.

Horie A, Tomita Y, Ohshio K, Fujiwara D, Fujii T.

BMC Microbiol. 2019 May 6;19(1):88. doi: 10.1186/s12866-019-1458-y.

4.

The Effects of Plasmacytoid Dendritic Cell-Stimulative Lactic Acid Bacteria, Lactococcus lactis Strain Plasma, on Exercise-Induced Fatigue and Recovery via Immunomodulatory Action.

Kokubo T, Komano Y, Tsuji R, Fujiwara D, Fujii T, Kanauchi O.

Int J Sport Nutr Exerc Metab. 2019 Jul 1;29(4):354–358. doi: 10.1123/ijsnem.2018-0377.

PMID:
31034253
5.

Lactobacillus paracasei KW3110 Prevents Blue Light-Induced Inflammation and Degeneration in the Retina.

Morita Y, Miwa Y, Jounai K, Fujiwara D, Kurihara T, Kanauchi O.

Nutrients. 2018 Dec 15;10(12). pii: E1991. doi: 10.3390/nu10121991.

6.

Long-term intake of Lactobacillus paracasei KW3110 prevents age-related chronic inflammation and retinal cell loss in physiologically aged mice.

Morita Y, Jounai K, Sakamoto A, Tomita Y, Sugihara Y, Suzuki H, Ohshio K, Otake M, Fujiwara D, Kanauchi O, Maruyama M.

Aging (Albany NY). 2018 Oct 19;10(10):2723-2740. doi: 10.18632/aging.101583.

7.

Administration of plasmacytoid dendritic cell-stimulative lactic acid bacteria enhances antigen-specific immune responses.

Suzuki H, Jounai K, Ohshio K, Fujii T, Fujiwara D.

Biochem Biophys Res Commun. 2018 Sep 10;503(3):1315-1321. doi: 10.1016/j.bbrc.2018.07.042. Epub 2018 Jul 12.

PMID:
30007441
8.

Long-term administration of pDC-Stimulative Lactococcus lactis strain decelerates senescence and prolongs the lifespan of mice.

Sugimura T, Jounai K, Ohshio K, Suzuki H, Kirisako T, Sugihara Y, Fujiwara D.

Int Immunopharmacol. 2018 May;58:166-172. doi: 10.1016/j.intimp.2018.03.024. Epub 2018 Mar 30.

PMID:
29605632
9.

Improvement of skin conditions by ingestion of Aspergillus kawachii (Koji) extract containing 14-dehydroergosterol in a randomized, double-blind, controlled trial.

Sugihara Y, Ikushima S, Miyake M, Kirisako T, Yada Y, Fujiwara D.

Clin Cosmet Investig Dermatol. 2018 Mar 9;11:115-124. doi: 10.2147/CCID.S152979. eCollection 2018.

10.

Identification and characterization of the first β-1,3-d-xylosidase from a gram-positive bacterium, Streptomyces sp. SWU10.

Phuengmaung P, Fujiwara D, Sukhumsirichart W, Sakamoto T.

Enzyme Microb Technol. 2018 May;112:72-78. doi: 10.1016/j.enzmictec.2017.11.002. Epub 2017 Nov 10.

PMID:
29499784
11.

Enhancement of immunomodulative effect of lactic acid bacteria on plasmacytoid dendritic cells with sucrose palmitate.

Kanayama M, Kato Y, Tsuji T, Konoeda Y, Hashimoto A, Kanauchi O, Fujii T, Fujiwara D.

Sci Rep. 2018 Feb 16;8(1):3147. doi: 10.1038/s41598-018-21527-2.

12.

Administration of Lactococcus lactis strain Plasma induces maturation of plasmacytoid dendritic cells and protection from rotavirus infection in suckling mice.

Jounai K, Sugimura T, Morita Y, Ohshio K, Fujiwara D.

Int Immunopharmacol. 2018 Mar;56:205-211. doi: 10.1016/j.intimp.2018.01.034. Epub 2018 Feb 3.

PMID:
29414652
13.
14.

Identification of 14-dehydroergosterol as a novel anti-inflammatory compound inducing tolerogenic dendritic cells.

Ano Y, Ikado K, Shindo K, Koizumi H, Fujiwara D.

Sci Rep. 2017 Oct 24;7(1):13903. doi: 10.1038/s41598-017-14446-1.

15.

Arabinogalactan Proteins Accumulate in the Cell Walls of Searching Hyphae of the Stem Parasitic Plants, Cuscuta campestris and Cuscuta japonica.

Hozumi A, Bera S, Fujiwara D, Obayashi T, Yokoyama R, Nishitani K, Aoki K.

Plant Cell Physiol. 2017 Nov 1;58(11):1868-1877. doi: 10.1093/pcp/pcx121.

PMID:
29016904
16.

Statins induce apoptosis through inhibition of Ras signaling pathways and enhancement of Bim and p27 expression in human hematopoietic tumor cells.

Fujiwara D, Tsubaki M, Takeda T, Tomonari Y, Koumoto YI, Sakaguchi K, Nishida S.

Tumour Biol. 2017 Oct;39(10):1010428317734947. doi: 10.1177/1010428317734947.

PMID:
28990465
17.

Successful use of etoposide for pyoderma gangrenosum associated with myelodysplastic syndrome and trisomy 8: cytokine profiles during treatment.

Fujiwara D, Hamada T, Yamasaki O, Sando Y, Saeki K, Fujii N, Kawakami Y, Iwatsuki K.

Eur J Dermatol. 2017 Oct 1;27(5):525-527. doi: 10.1684/ejd.2017.3067. No abstract available.

PMID:
28943508
18.

Mechanical Thrombectomy for Acute Ischemic Stroke Patients Aged 80 Years or Older.

Imahori T, Tanaka K, Arai A, Shiomi R, Fujiwara D, Mori T, Yokote A, Matsushima K, Matsui D, Kobayashi M, Fujita A, Hosoda K, Kohmura E.

J Stroke Cerebrovasc Dis. 2017 Dec;26(12):2793-2799. doi: 10.1016/j.jstrokecerebrovasdis.2017.06.060. Epub 2017 Jul 25.

PMID:
28754235
19.

Cut-off point for chair stand time when used as a surrogate for gait speed in sarcopenia diagnosis.

Fujiwara D, Wakabayashi H.

Geriatr Gerontol Int. 2017 Apr;17(4):667-668. doi: 10.1111/ggi.12852. No abstract available.

PMID:
28405974
20.

[Influence of Next-Day Administration of Pegfilgrastim after FEC100 Chemotherapy in Japanese with Breast Cancer on Neutrophil Count].

Fujiwara D, Mashimo K, Kimura K, Noda A, Taki K, Yoshibayashi H, Takeda T, Tsubaki M, Nishida S, Sakaguchi K.

Gan To Kagaku Ryoho. 2017 Feb;44(2):149-152. Japanese.

PMID:
28223672
21.

Magnetic Control of the Charge-Separated State Lifetime Realized by Covalent Attachment of a Platinum Complex.

Miura T, Fujiwara D, Akiyama K, Horikoshi T, Suzuki S, Kozaki M, Okada K, Ikoma T.

J Phys Chem Lett. 2017 Feb 2;8(3):661-665. doi: 10.1021/acs.jpclett.6b02887. Epub 2017 Jan 23.

PMID:
28085290
22.

The sensitivity of head and neck carcinoma cells to statins is related to the expression of their Ras expression status, and statin-induced apoptosis is mediated via suppression of the Ras/ERK and Ras/mTOR pathways.

Tsubaki M, Fujiwara D, Takeda T, Kino T, Tomonari Y, Itoh T, Imano M, Satou T, Sakaguchi K, Nishida S.

Clin Exp Pharmacol Physiol. 2017 Feb;44(2):222-234. doi: 10.1111/1440-1681.12690.

PMID:
27805296
23.

A Cyclized Helix-Loop-Helix Peptide as a Molecular Scaffold for the Design of Inhibitors of Intracellular Protein-Protein Interactions by Epitope and Arginine Grafting.

Fujiwara D, Kitada H, Oguri M, Nishihara T, Michigami M, Shiraishi K, Yuba E, Nakase I, Im H, Cho S, Joung JY, Kodama S, Kono K, Ham S, Fujii I.

Angew Chem Int Ed Engl. 2016 Aug 26;55(36):10612-5. doi: 10.1002/anie.201603230. Epub 2016 Jul 28.

PMID:
27467415
24.

DNA module platform for developing colorimetric aptamer sensors.

Tomita Y, Morita Y, Suga H, Fujiwara D.

Biotechniques. 2016 Jun 1;60(6):285-92. doi: 10.2144/000114425. eCollection 2016.

25.

Departure of microscopic friction from macroscopic drag in molecular fluid dynamics.

Hanasaki I, Fujiwara D, Kawano S.

J Chem Phys. 2016 Mar 7;144(9):094503. doi: 10.1063/1.4943045.

PMID:
26957167
26.

Macrocyclization and labeling of helix-loop-helix peptide with intramolecular bis-thioether linkage.

Nishihara T, Kitada H, Fujiwara D, Fujii I.

Biopolymers. 2016 Nov 4;106(4):415-21. doi: 10.1002/bip.22826.

PMID:
26917088
27.

Aminopeptidase N (APN/CD13) as a target molecule for scirrhous gastric cancer.

Nohara S, Kato K, Fujiwara D, Sakuragi N, Yanagihara K, Iwanuma Y, Kajiyama Y.

Clin Res Hepatol Gastroenterol. 2016 Sep;40(4):494-503. doi: 10.1016/j.clinre.2015.11.003. Epub 2016 Jan 13.

PMID:
26774363
28.

Statins improve survival by inhibiting spontaneous metastasis and tumor growth in a mouse melanoma model.

Tsubaki M, Takeda T, Kino T, Obata N, Itoh T, Imano M, Mashimo K, Fujiwara D, Sakaguchi K, Satou T, Nishida S.

Am J Cancer Res. 2015 Sep 15;5(10):3186-97. eCollection 2015.

29.

Lactococcus lactis subsp. lactis JCM 5805 activates natural killer cells via dendritic cells.

Suzuki H, Ohshio K, Fujiwara D.

Biosci Biotechnol Biochem. 2016;80(4):798-800. doi: 10.1080/09168451.2015.1116922. Epub 2015 Dec 1.

PMID:
26623718
30.

A reliable serum C-peptide index for the selection of an insulin regimen to achieve good glycemic control in obese patients with type 2 diabetes: an analysis from a short-term study with intensive insulin therapy.

Suzuki T, Takahashi K, Fujiwara D, Shii M, Takekawa S, Matsuoka T.

Diabetol Int. 2015 Oct 6;7(3):235-243. doi: 10.1007/s13340-015-0239-6. eCollection 2016 Sep.

31.

Effects of oral intake of plasmacytoid dendritic cells-stimulative lactic acid bacterial strain on pathogenesis of influenza-like illness and immunological response to influenza virus.

Sugimura T, Takahashi H, Jounai K, Ohshio K, Kanayama M, Tazumi K, Tanihata Y, Miura Y, Fujiwara D, Yamamoto N.

Br J Nutr. 2015 Sep 14;114(5):727-33. doi: 10.1017/S0007114515002408. Epub 2015 Aug 3.

PMID:
26234407
32.

Molecular characterization of a Penicillium chrysogenum exo-rhamnogalacturonan lyase that is structurally distinct from other polysaccharide lyase family proteins.

Iwai M, Kawakami T, Ikemoto T, Fujiwara D, Takenaka S, Nakazawa M, Ueda M, Sakamoto T.

Appl Microbiol Biotechnol. 2015 Oct;99(20):8515-25. doi: 10.1007/s00253-015-6600-7. Epub 2015 Apr 29.

PMID:
25921806
33.

Draft Genome Sequence of Lactococcus lactis subsp. lactis JCM 5805T, a Strain That Induces Plasmacytoid Dendritic Cell Activation.

Fujii T, Tomita Y, Ikushima S, Horie A, Fujiwara D.

Genome Announc. 2015 Mar 19;3(2). pii: e00113-15. doi: 10.1128/genomeA.00113-15.

34.

Oral administration of Lactococcus lactis subsp. lactis JCM5805 enhances lung immune response resulting in protection from murine parainfluenza virus infection.

Jounai K, Sugimura T, Ohshio K, Fujiwara D.

PLoS One. 2015 Mar 6;10(3):e0119055. doi: 10.1371/journal.pone.0119055. eCollection 2015.

35.

Biochemical Characterization and Overexpression of an Endo-rhamnogalacturonan Lyase from Penicillium chrysogenum.

Iwai M, Yamada H, Ikemoto T, Matsumoto S, Fujiwara D, Takenaka S, Sakamoto T.

Mol Biotechnol. 2015 Jun;57(6):539-48. doi: 10.1007/s12033-015-9847-4.

PMID:
25666014
36.

Bisphosphonates and statins inhibit expression and secretion of MIP-1α via suppression of Ras/MEK/ERK/AML-1A and Ras/PI3K/Akt/AML-1A pathways.

Tsubaki M, Takeda T, Sakamoto K, Shimaoka H, Fujita A, Itoh T, Imano M, Mashimo K, Fujiwara D, Sakaguchi K, Satou T, Nishida S.

Am J Cancer Res. 2014 Dec 15;5(1):168-79. eCollection 2015.

37.

Lignin-rich enzyme lignin (LREL), a cellulase-treated lignin-carbohydrate derived from plants, activates myeloid dendritic cells via Toll-like receptor 4 (TLR4).

Tsuji R, Koizumi H, Aoki D, Watanabe Y, Sugihara Y, Matsushita Y, Fukushima K, Fujiwara D.

J Biol Chem. 2015 Feb 13;290(7):4410-21. doi: 10.1074/jbc.M114.593673. Epub 2014 Dec 29.

38.

Postprandial serum C-peptide value is the optimal index to identify patients with non-obese type 2 diabetes who require multiple daily insulin injection: Analysis of C-peptide values before and after short-term intensive insulin therapy.

Fujiwara D, Takahashi K, Suzuki T, Shii M, Nakashima Y, Takekawa S, Yoshida A, Matsuoka T.

J Diabetes Investig. 2013 Nov 27;4(6):618-25. doi: 10.1111/jdi.12103. Epub 2013 May 30.

39.

Peptide-based immunoadsorbents: molecular grafting of IgG-Fc-binding epitopes of Protein A onto a de novo-designed helix-loop-helix peptide.

Kawabata K, Nagai H, Konishi N, Fujiwara D, Sasaki R, Ichikawa T, Fujii I.

Bioorg Med Chem. 2014 Mar 15;22(6):1845-9. doi: 10.1016/j.bmc.2014.01.053. Epub 2014 Feb 6.

PMID:
24556503
40.

Nitrogen-containing bisphosphonates inhibit RANKL- and M-CSF-induced osteoclast formation through the inhibition of ERK1/2 and Akt activation.

Tsubaki M, Komai M, Itoh T, Imano M, Sakamoto K, Shimaoka H, Takeda T, Ogawa N, Mashimo K, Fujiwara D, Mukai J, Sakaguchi K, Satou T, Nishida S.

J Biomed Sci. 2014 Feb 3;21:10. doi: 10.1186/1423-0127-21-10.

41.

Phage selection of peptide "microantibodies".

Fujiwara D, Fujii I.

Curr Protoc Chem Biol. 2013;5(3):171-94. doi: 10.1002/9780470559277.ch130039.

PMID:
24391082
42.

Immunomodulatory effect of Lactococcus lactis JCM5805 on human plasmacytoid dendritic cells.

Sugimura T, Jounai K, Ohshio K, Tanaka T, Suwa M, Fujiwara D.

Clin Immunol. 2013 Dec;149(3):509-18. doi: 10.1016/j.clim.2013.10.007. Epub 2013 Oct 25. Erratum in: Clin Immunol. 2015 Dec;161(2):156.

PMID:
24239838
43.

By inhibiting Src, verapamil and dasatinib overcome multidrug resistance via increased expression of Bim and decreased expressions of MDR1 and survivin in human multidrug-resistant myeloma cells.

Tsubaki M, Komai M, Itoh T, Imano M, Sakamoto K, Shimaoka H, Takeda T, Ogawa N, Mashimo K, Fujiwara D, Mukai J, Sakaguchi K, Satou T, Nishida S.

Leuk Res. 2014 Jan;38(1):121-30. doi: 10.1016/j.leukres.2013.10.017. Epub 2013 Oct 28.

PMID:
24239173
44.

Activation of NF-κB by the RANKL/RANK system up-regulates snail and twist expressions and induces epithelial-to-mesenchymal transition in mammary tumor cell lines.

Tsubaki M, Komai M, Fujimoto S, Itoh T, Imano M, Sakamoto K, Shimaoka H, Takeda T, Ogawa N, Mashimo K, Fujiwara D, Mukai J, Sakaguchi K, Satou T, Nishida S.

J Exp Clin Cancer Res. 2013 Sep 5;32:62. doi: 10.1186/1756-9966-32-62.

45.

Inhibition of the tumour necrosis factor-alpha autocrine loop enhances the sensitivity of multiple myeloma cells to anticancer drugs.

Tsubaki M, Komai M, Itoh T, Imano M, Sakamoto K, Shimaoka H, Ogawa N, Mashimo K, Fujiwara D, Takeda T, Mukai J, Sakaguchi K, Satou T, Nishida S.

Eur J Cancer. 2013 Nov;49(17):3708-17. doi: 10.1016/j.ejca.2013.07.010. Epub 2013 Aug 7.

PMID:
23932230
46.

Utility of weekly docetaxel combined with preoperative radiotherapy for locally advanced esophageal cancer from pathological analysis.

Kushida T, Nohara S, Yoshino K, Fujiwara D, Ouchi K, Amano T, Isayama F, Tomita N, Iwanuma Y, Sasai K, Tsurumaru M, Kajiyama Y.

Dis Esophagus. 2014 May-Jun;27(4):368-73. doi: 10.1111/dote.12105. Epub 2013 Jul 19.

PMID:
23865505
47.

The crystal structure of multidrug-resistance regulator RamR with multiple drugs.

Yamasaki S, Nikaido E, Nakashima R, Sakurai K, Fujiwara D, Fujii I, Nishino K.

Nat Commun. 2013;4:2078. doi: 10.1038/ncomms3078.

PMID:
23800819
48.

The usefulness of three-dimensional cell culture in induction of cancer stem cells from esophageal squamous cell carcinoma cell lines.

Fujiwara D, Kato K, Nohara S, Iwanuma Y, Kajiyama Y.

Biochem Biophys Res Commun. 2013 May 17;434(4):773-8. doi: 10.1016/j.bbrc.2013.04.008. Epub 2013 Apr 18.

PMID:
23602898
49.

Spherical lactic acid bacteria activate plasmacytoid dendritic cells immunomodulatory function via TLR9-dependent crosstalk with myeloid dendritic cells.

Jounai K, Ikado K, Sugimura T, Ano Y, Braun J, Fujiwara D.

PLoS One. 2012;7(4):e32588. doi: 10.1371/journal.pone.0032588. Epub 2012 Apr 10.

50.

Pain questionnaire development focusing on cross-cultural equivalence to the original questionnaire: the Japanese version of the Short-Form McGill Pain Questionnaire.

Arimura T, Hosoi M, Tsukiyama Y, Yoshida T, Fujiwara D, Tanaka M, Tamura R, Nakashima Y, Sudo N, Kubo C.

Pain Med. 2012 Apr;13(4):541-51. doi: 10.1111/j.1526-4637.2012.01333.x. Epub 2012 Feb 23.

PMID:
22360795

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