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The Oncogene Addiction Switch from NOTCH to PI3K Requires Simultaneous Targeting of NOTCH and PI3K Pathway Inhibition in Glioblastoma.

Saito N, Hirai N, Aoki K, Suzuki R, Fujita S, Nakayama H, Hayashi M, Ito K, Sakurai T, Iwabuchi S.

Cancers (Basel). 2019 Jan 20;11(1). pii: E121. doi: 10.3390/cancers11010121.


A Nationwide Comparison Between Sepsis-2 and Sepsis-3 Definition in Japan.

Takauji S, Hayakawa M, Fujita S.

J Intensive Care Med. 2019 Jan 13:885066618823151. doi: 10.1177/0885066618823151. [Epub ahead of print]


Complete resolution of giant cell arteritis after tocilizumab monotherapy determined by positron emission tomography-CT.

Akagi T, Fujita S, Mukai T, Morita Y.

BMJ Case Rep. 2019 Jan 10;12(1). pii: bcr-2018-228697. doi: 10.1136/bcr-2018-228697. No abstract available.


Improving the Quality of Synthetic FLAIR Images with Deep Learning Using a Conditional Generative Adversarial Network for Pixel-by-Pixel Image Translation.

Hagiwara A, Otsuka Y, Hori M, Tachibana Y, Yokoyama K, Fujita S, Andica C, Kamagata K, Irie R, Koshino S, Maekawa T, Chougar L, Wada A, Takemura MY, Hattori N, Aoki S.

AJNR Am J Neuroradiol. 2019 Jan 10. doi: 10.3174/ajnr.A5927. [Epub ahead of print]


DKK3 knockdown confers negative effects on the malignant potency of head and neck squamous cell carcinoma cells via the PI3K/Akt and MAPK signaling pathways.

Katase N, Nishimatsu SI, Yamauchi A, Yamamura M, Fujita S.

Int J Oncol. 2018 Dec 14. doi: 10.3892/ijo.2018.4667. [Epub ahead of print]


Menthol-induced facilitation of cerebrocortical excitatory propagation induced by air puff stimulation of the nasal cavity in the rat: An optical imaging study.

Fujita S, Zama M, Kaneko K, Murayama S, Ohtani S, Usui M, Noma D, Tsuda H, Yamamoto K, Kobayashi M.

Neurosci Lett. 2018 Dec 13;696:87-92. doi: 10.1016/j.neulet.2018.12.018. [Epub ahead of print]


Effects of recombinant thrombomodulin therapy and soluble human leukocyte antigen-G levels during hematopoietic stem cell transplantation.

Nomura S, Ito T, Katayama Y, Ota S, Hayashi K, Fujita S, Satake A, Ishii K.

Transpl Immunol. 2018 Dec 10. pii: S0966-3274(18)30159-X. doi: 10.1016/j.trim.2018.12.001. [Epub ahead of print]


Thoracic endografting increases cardiac afterload and leads to left ventricular hypertrophy in dogs.

Yamashita Y, Oishi Y, Motomatsu Y, Hirayama K, Harada T, Ushijima T, Fujita S, Kimura S, Sonoda H, Tatewaki H, Tanoue Y, Sunagawa G, Nishikawa T, Saku K, Shiose A.

Eur J Cardiothorac Surg. 2018 Dec 7. doi: 10.1093/ejcts/ezy402. [Epub ahead of print]


Leaflet-base-preserving truncal valve repair with ethanol-treated autologous pericardium.

Fujita S, Yamagishi M, Miyazaki T, Yaku H.

J Thorac Cardiovasc Surg. 2018 Sep 28. pii: S0022-5223(18)32498-X. doi: 10.1016/j.jtcvs.2018.08.103. [Epub ahead of print] No abstract available.


Skipping breakfast is associated with lower fat-free mass in healthy young subjects: a cross-sectional study.

Yasuda J, Asako M, Arimitsu T, Fujita S.

Nutr Res. 2018 Dec;60:26-32. doi: 10.1016/j.nutres.2018.09.006. Epub 2018 Sep 19.


A Comparison of Techniques for Correcting Eddy-current and Motion-induced Distortions in Diffusion-weighted Echo-planar Images.

Haneda J, Hagiwara A, Hori M, Wada A, Fukunaga I, Murata K, Kamagata K, Fujita S, Maekawa T, Irie R, Takamura T, Suzuki M, Kunishima Kumamaru K, Aoki S.

Magn Reson Med Sci. 2018 Dec 3. doi: 10.2463/ [Epub ahead of print]


Differentiating Alzheimer's Disease from Dementia with Lewy Bodies Using a Deep Learning Technique Based on Structural Brain Connectivity.

Wada A, Tsuruta K, Irie R, Kamagata K, Maekawa T, Fujita S, Koshino S, Kumamaru K, Suzuki M, Nakanishi A, Hori M, Aoki S.

Magn Reson Med Sci. 2018 Dec 3. doi: 10.2463/ [Epub ahead of print]


The trinuclear platinum(ii) complex in Vèzes' red salt as a building block of coordination polymers.

Hoshino N, Fujita S, Akutagawa T.

Dalton Trans. 2018 Dec 18;48(1):176-181. doi: 10.1039/c8dt04121k.


Response to the Letter to the Editor.

Fujita S.

Ann Surg. 2018 Nov 29. doi: 10.1097/SLA.0000000000003119. [Epub ahead of print] No abstract available.


Abrupt ice-age shifts in southern westerly winds and Antarctic climate forced from the north.

Buizert C, Sigl M, Severi M, Markle BR, Wettstein JJ, McConnell JR, Pedro JB, Sodemann H, Goto-Azuma K, Kawamura K, Fujita S, Motoyama H, Hirabayashi M, Uemura R, Stenni B, Parrenin F, He F, Fudge TJ, Steig EJ.

Nature. 2018 Nov;563(7733):681-685. doi: 10.1038/s41586-018-0727-5. Epub 2018 Nov 28.


Predictive factors of pathological lateral pelvic lymph node metastasis in patients without clinical lateral pelvic lymph node metastasis (clinical stage II/III): The analysis of data from the clinical trial (JCOG0212).

Komori K, Fujita S, Mizusawa J, Kanemitsu Y, Ito M, Shiomi A, Ohue M, Ota M, Akazai Y, Shiozawa M, Yamaguchi T, Bandou H, Katsumata K, Kinugasa Y, Takii Y, Akasu T, Moriya Y; Colorectal Cancer Study Group of Japan Clinical Oncology Group.

Eur J Surg Oncol. 2018 Nov 20. pii: S0748-7983(18)32014-6. doi: 10.1016/j.ejso.2018.11.016. [Epub ahead of print]


Haematological analysis of Japanese macaques (Macaca fuscata) in the area affected by the Fukushima Daiichi Nuclear Power Plant accident.

Urushihara Y, Suzuki T, Shimizu Y, Ohtaki M, Kuwahara Y, Suzuki M, Uno T, Fujita S, Saito A, Yamashiro H, Kino Y, Sekine T, Shinoda H, Fukumoto M.

Sci Rep. 2018 Nov 13;8(1):16748. doi: 10.1038/s41598-018-35104-0.


Medication-related osteonecrosis of the jaw after tooth extraction in cancer patients: a multicenter retrospective study.

Hasegawa T, Hayashida S, Kondo E, Takeda Y, Miyamoto H, Kawaoka Y, Ueda N, Iwata E, Nakahara H, Kobayashi M, Soutome S, Yamada SI, Tojyo I, Kojima Y, Umeda M, Fujita S, Kurita H, Shibuya Y, Kirita T, Komori T; Japanese Study Group of Co-operative Dentistry with Medicine (JCDM).

Osteoporos Int. 2019 Jan;30(1):231-239. doi: 10.1007/s00198-018-4746-8. Epub 2018 Nov 7.


Single type infection of human papillomavirus as a cause for high-grade cervical intraepithelial neoplasia and invasive cancer in Japan.

Sakamoto J, Kamiura S, Okayama K, Okodo M, Shibata T, Osaka Y, Fujita S, Takata E, Takagi H, Takakura M, Sasagawa T.

Papillomavirus Res. 2018 Dec;6:46-51. doi: 10.1016/j.pvr.2018.10.001. Epub 2018 Oct 26.


Long-Term Growth of the Neoaortic Root after Arterial Switch Operation.

Oda S, Nakano T, Fujita S, Sakaguchi S, Kado H.

Ann Thorac Surg. 2018 Oct 31. pii: S0003-4975(18)31540-6. doi: 10.1016/j.athoracsur.2018.09.025. [Epub ahead of print]


[A Case of Recurrent Colon Cancer with Peritoneal Dissemination Treated with Aflibercept Showing Partial Response for One Year].

Gonda K, Fujita S, Shibata M, Hatakeyama Y, Tachiya Y, Rokkaku Y, Saze Z, Momma T, Ohki S, Saji S, Kono K.

Gan To Kagaku Ryoho. 2018 Oct;45(10):1539-1542. Japanese.


[A Case of Rectal Colon Cancer with Paraneoplastic Cerebellar Degeneration].

Gonda K, Kikuchi T, Shibata M, Hatakeyama Y, Tachiya Y, Rokkaku Y, Endo H, Fujita S, Sakamoto W, Hayase S, Okayama H, Hanayama H, Tada T, Nirei A, Ujiie D, Yamada R, Saze Z, Momma T, Ohki S, Kono K.

Gan To Kagaku Ryoho. 2018 Oct;45(10):1510-1512. Japanese.


Exercise-induced mitochondrial biogenesis coincides with the expression of mitochondrial translation factors in murine skeletal muscle.

Yokokawa T, Kido K, Suga T, Isaka T, Hayashi T, Fujita S.

Physiol Rep. 2018 Oct;6(20):e13893. doi: 10.14814/phy2.13893.


Exercise training increases CISD family protein expression in murine skeletal muscle and white adipose tissue.

Yokokawa T, Kido K, Suga T, Sase K, Isaka T, Hayashi T, Fujita S.

Biochem Biophys Res Commun. 2018 Nov 30;506(3):571-577. doi: 10.1016/j.bbrc.2018.10.101. Epub 2018 Oct 23.


Muscle Androgen Receptor Content but Not Systemic Hormones Is Associated With Resistance Training-Induced Skeletal Muscle Hypertrophy in Healthy, Young Men.

Morton RW, Sato K, Gallaugher MPB, Oikawa SY, McNicholas PD, Fujita S, Phillips SM.

Front Physiol. 2018 Oct 9;9:1373. doi: 10.3389/fphys.2018.01373. eCollection 2018.


Long-term outcome of renal function in children after stem cell transplantation measured by estimated glomerular filtration rate.

Ukeba-Terashita Y, Kobayashi R, Hori D, Matsushima S, Sano H, Suzuki D, Nakajima M, Suzuki M, Ueno M, Fujita S, Kobayashi K.

Pediatr Blood Cancer. 2019 Feb;66(2):e27478. doi: 10.1002/pbc.27478. Epub 2018 Oct 23.


Dual inhibition of enhancer of zeste homolog 1/2 overactivates WNT signaling to deplete cancer stem cells in multiple myeloma.

Nakagawa M, Fujita S, Katsumoto T, Yamagata K, Ogawara Y, Hattori A, Kagiyama Y, Honma D, Araki K, Inoue T, Kato A, Inaki K, Wada C, Ono Y, Yamamoto M, Miura O, Nakashima Y, Kitabayashi I.

Cancer Sci. 2019 Jan;110(1):194-208. doi: 10.1111/cas.13840. Epub 2018 Nov 16.


Effect of Mixed Meal and Leucine Intake on Plasma Amino Acid Concentrations in Young Men.

Yoshii N, Sato K, Ogasawara R, Nishimura Y, Shinohara Y, Fujita S.

Nutrients. 2018 Oct 18;10(10). pii: E1543. doi: 10.3390/nu10101543.


Efficient transient protein expression in tomato cultivars and wild species using agroinfiltration-mediated high expression system.

Hoshikawa K, Fujita S, Renhu N, Ezura K, Yamamoto T, Nonaka S, Ezura H, Miura K.

Plant Cell Rep. 2019 Jan;38(1):75-84. doi: 10.1007/s00299-018-2350-1. Epub 2018 Oct 17.


[Pacemaker Dislocation into the Peritoneal Cavity].

Tani K, Murata A, Nakagaki S, Otaka S, Sotokawa M, Ueda T, Fujita S, Hatasaki K, Iwasaki H, Saito T, Ota K.

Kyobu Geka. 2018 Oct;71(11):919-923. Japanese.


A quantitative morphological analysis of three-dimensional CT coxal bone images of contemporary Japanese using homologous models for sex and age estimation.

Biwasaka H, Aoki Y, Takahashi Y, Fukuta M, Usui A, Hosokai Y, Saito H, Funayama M, Fujita S, Takamiya M, Dewa K.

Leg Med (Tokyo). 2019 Feb;36:1-8. doi: 10.1016/j.legalmed.2018.09.017. Epub 2018 Oct 1.


Identification of drug transporters contributing to oxaliplatin-induced peripheral neuropathy.

Fujita S, Hirota T, Sakiyama R, Baba M, Ieiri I.

J Neurochem. 2018 Oct 8. doi: 10.1111/jnc.14607. [Epub ahead of print]


Eosinophilic Granulomatosis with Polyangiitis (EGPA) with an Unusual Manifestation of Mid-Ventricular Obstruction Caused by Endocardial Thrombus.

Ito T, Fujita SI, Kanzaki Y, Sohmiya K, Hoshiga M.

Am J Case Rep. 2018 Oct 8;19:1197-1203. doi: 10.12659/AJCR.910861.


Relationship between the fluorescence intensity of rhodamine-labeled orexin A and the calcium responses in cortical neurons: An in vivo two-photon calcium imaging study.

Ohtani S, Fujita S, Hasegawa K, Tsuda H, Tonogi M, Kobayashi M.

J Pharmacol Sci. 2018 Sep;138(1):76-82. doi: 10.1016/j.jphs.2018.09.005. Epub 2018 Sep 22.


Clinical significance of dasatinib-induced pleural effusion in patients with de novo chronic myeloid leukemia.

Nakaya A, Fujita S, Satake A, Nakanishi T, Azuma Y, Tsubokura Y, Hotta M, Yoshimura H, Ishii K, Ito T, Nomura S.

Hematol Rep. 2018 Sep 5;10(3):7474. doi: 10.4081/hr.2018.7474. eCollection 2018 Sep 5.


Comprehensive cost of illness of dementia in Japan: a time trend analysis based on Japanese official statistics.

Hanaoka S, Matsumoto K, Kitazawa T, Fujita S, Seto K, Hasegawa T.

Int J Qual Health Care. 2018 Sep 29. doi: 10.1093/intqhc/mzy176. [Epub ahead of print]


Team Management of Skin Rash Associated with Use of Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors.

Masago K, Imamichi F, Masuda Y, Ariga N, Fujitomi K, Fukumine Y, Hatakenaka K, Fujita S, Katakami N.

Asia Pac J Oncol Nurs. 2018 Oct-Dec;5(4):430-434. doi: 10.4103/apjon.apjon_33_18.


Malignant Transformation of an Ovarian Endometrioma during Endometriosis Treatment: A Case Report.

Takagi H, Takata E, Sakamoto J, Fujita S, Takakura M, Sasagawa T.

Case Rep Obstet Gynecol. 2018 Sep 4;2018:6210172. doi: 10.1155/2018/6210172. eCollection 2018.


Combined Use of Ninjin'yoeito Improves Subjective Fatigue Caused by Lenalidomide in Patients With Multiple Myeloma: A Retrospective Study.

Ito T, Konishi A, Tsubokura Y, Azuma Y, Hotta M, Yoshimura H, Nakanishi T, Fujita S, Nakaya A, Satake A, Ishii K, Nomura S.

Front Nutr. 2018 Aug 21;5:72. doi: 10.3389/fnut.2018.00072. eCollection 2018.


[Occurrence of acquired factor V inhibitor during antibiotic therapy for a surgical wound infection].

Okabe T, Ueno H, Fujita S, Kagoo T, Boku S, Yano T, Yokoyama A.

Rinsho Ketsueki. 2018;59(8):1007-1011. doi: 10.11406/rinketsu.59.1007. Japanese.


[Successful treatment with brentuximab vedotin maintenance therapy after autologous stem cell transplantation in high-risk Hodgkin lymphoma].

Ishii K, Azuma Y, Konishi A, Tsubokura Y, Yoshimura H, Hotta M, Nakanishi T, Nakaya A, Fujita S, Satake A, Miyaji M, Ito T, Nomura S.

Rinsho Ketsueki. 2018;59(8):1002-1006. doi: 10.11406/rinketsu.59.1002. Japanese.


The comparison of early healing 1-month after PCI among CoCr-everolimus-eluting stent (EES), biodegradable polymer (BP)-EES and BP-sirolimus-eluting stent: Insights from OFDI and coronary angioscopy.

Sato T, Taya Y, Suzuki N, Yuasa S, Kishi S, Koshikawa T, Fuse K, Fujita S, Ikeda Y, Kitazawa H, Takahashi M, Okabe M, Aizawa Y.

Int J Cardiol Heart Vasc. 2018 Aug 17;20:40-45. doi: 10.1016/j.ijcha.2018.08.001. eCollection 2018 Sep.


Acute pulmonary hemorrhage during atrial fibrillation HotBalloon ablation.

Fujii E, Fujita S, Kagawa Y, Ito M.

J Arrhythm. 2018 Jun 12;34(4):462-464. doi: 10.1002/joa3.12080. eCollection 2018 Aug.


Catecholaminergic polymorphic ventricular tachycardia managed as orthostatic dysregulation and epilepsy in 11- and 15-year-old sisters.

Fujita S, Nishida K, Irabu H, Nakagawa R, Futatani T, Igarashi N, Usuda K, Nagata Y, Ohno S, Horie M, Hatasaki K.

Pediatr Int. 2018 Nov;60(11):998-1001. doi: 10.1111/ped.13688.


Risk of malnutrition is associated with poor physical function in patients undergoing cardiac rehabilitation following heart failure.

Matsuo H, Yoshimura Y, Fujita S, Maeno Y.

Nutr Diet. 2018 Aug 28. doi: 10.1111/1747-0080.12465. [Epub ahead of print]


Case of a novel PAX6 mutation with aniridia and insulin-dependent diabetes mellitus.

Motoda S, Fujita S, Kozawa J, Kimura T, Fukui K, Ikuno Y, Imagawa A, Iwahashi H, Shimomura I.

J Diabetes Investig. 2018 Aug 27. doi: 10.1111/jdi.12902. [Epub ahead of print]


Bacteremia Possibly Caused by Helicobacter cinaedi and Associated with Painful Erythema in Rheumatoid Arthritis with Malignant Lymphoma.

Fujita S, Hayashi H, Kodama S, Mukai T, Morita Y.

Intern Med. 2018 Dec 15;57(24):3663-3666. doi: 10.2169/internalmedicine.1196-18. Epub 2018 Aug 24.


Protein kinase A (PKA) inhibition reduces human aortic smooth muscle cell calcification stimulated by inflammatory response and inorganic phosphate.

Toita R, Otani K, Kawano T, Fujita S, Murata M, Kang JH.

Life Sci. 2018 Sep 15;209:466-471. doi: 10.1016/j.lfs.2018.08.051. Epub 2018 Aug 23.


The Comparison of Inappropriate-Low-Doses Use among 4 Direct Oral Anticoagulants in Patients with Atrial Fibrillation: From the Database of a Single-Center Registry.

Sato T, Aizawa Y, Fuse K, Fujita S, Ikeda Y, Kitazawa H, Takahashi M, Okabe M.

J Stroke Cerebrovasc Dis. 2018 Nov;27(11):3280-3288. doi: 10.1016/j.jstrokecerebrovasdis.2018.07.028. Epub 2018 Aug 16.


High-power visibly emitting Pr3+:YLF laser end pumped by single-emitter or fiber-coupled GaN blue laser diodes.

Tanaka H, Fujita S, Kannari F.

Appl Opt. 2018 Jul 20;57(21):5923-5928. doi: 10.1364/AO.57.005923.


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