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Items: 1 to 50 of 183

1.

A conserved strategy of chalcone isomerase-like protein to rectify promiscuous chalcone synthase specificity.

Waki T, Mameda R, Nakano T, Yamada S, Terashita M, Ito K, Tenma N, Li Y, Fujino N, Uno K, Yamashita S, Aoki Y, Denessiouk K, Kawai Y, Sugawara S, Saito K, Yonekura-Sakakibara K, Morita Y, Hoshino A, Takahashi S, Nakayama T.

Nat Commun. 2020 Feb 13;11(1):870. doi: 10.1038/s41467-020-14558-9.

2.

Decreased expression of a phagocytic receptor Siglec-1 on alveolar macrophages in chronic obstructive pulmonary disease.

Tanno A, Fujino N, Yamada M, Sugiura H, Hirano T, Tanaka R, Sano H, Suzuki S, Okada Y, Ichinose M.

Respir Res. 2020 Jan 28;21(1):30. doi: 10.1186/s12931-020-1297-2.

3.

Impact of functional studies on exome sequence variant interpretation in early-onset cardiac conduction system diseases.

Hayashi K, Teramoto R, Nomura A, Asano Y, Beerens M, Kurata Y, Kobayashi I, Fujino N, Furusho H, Sakata K, Onoue K, Chiang DY, Kiviniemi TO, Buys E, Sips P, Burch ML, Zhao Y, Kelly AE, Namura M, Kita Y, Tsuchiya T, Kaku B, Oe K, Takeda Y, Konno T, Inoue M, Fujita T, Kato T, Funada A, Tada H, Hodatsu A, Nakanishi C, Sakamoto Y, Tsuda T, Nagata Y, Tanaka Y, Okada H, Usuda K, Cui S, Saito Y, MacRae CA, Takashima S, Yamagishi M, Kawashiri MA, Takamura M.

Cardiovasc Res. 2020 Jan 24. pii: cvaa010. doi: 10.1093/cvr/cvaa010. [Epub ahead of print]

PMID:
31977013
4.

Improving the viability of tissue-resident stem cells using an organ-preservation solution.

Suzuki T, Ota C, Fujino N, Tando Y, Suzuki S, Yamada M, Kondo T, Okada Y, Kubo H.

FEBS Open Bio. 2019 Dec;9(12):2093-2104. doi: 10.1002/2211-5463.12748. Epub 2019 Nov 18.

5.

Development of a Visiting Nursing Practice Self-Evaluation Scale: Assessment of Skill for Caring for Individuals With Behavioral and Psychological Symptoms of Dementia.

Furuno T, Fujino N, Fujimoto Y, Shirai H, Iwamoto Y, Kamada Y, Yamaguchi F.

Res Gerontol Nurs. 2020 Jan 1;13(1):49-60. doi: 10.3928/19404921-20190930-01. Epub 2019 Oct 4.

PMID:
31584690
6.

Increase in circulating ACE-positive endothelial microparticles during acute lung injury.

Takei Y, Yamada M, Saito K, Kameyama Y, Sugiura H, Makiguchi T, Fujino N, Koarai A, Toyama H, Saito K, Ejima Y, Kawazoe Y, Kudo D, Kushimoto S, Yamauchi M, Ichinose M.

Eur Respir J. 2019 Oct 17;54(4). pii: 1801188. doi: 10.1183/13993003.01188-2018. Print 2019 Oct.

PMID:
31320458
7.

Sensing of apoptotic cells through Axl causes lung basal cell proliferation in inflammatory diseases.

Fujino N, Brand OJ, Morgan DJ, Fujimori T, Grabiec AM, Jagger CP, Maciewicz RA, Yamada M, Itakura K, Sugiura H, Ichinose M, Hussell T.

J Exp Med. 2019 Sep 2;216(9):2184-2201. doi: 10.1084/jem.20171978. Epub 2019 Jul 9.

8.

Nitrosative stress in patients with asthma-chronic obstructive pulmonary disease overlap.

Kyogoku Y, Sugiura H, Ichikawa T, Numakura T, Koarai A, Yamada M, Fujino N, Tojo Y, Onodera K, Tanaka R, Sato K, Sano H, Yamanaka S, Itakura K, Mitsune A, Tamada T, Akaike T, Ichinose M.

J Allergy Clin Immunol. 2019 Oct;144(4):972-983.e14. doi: 10.1016/j.jaci.2019.04.023. Epub 2019 May 9.

PMID:
31077687
9.

Impact of renal function on mid-term outcomes in heart failure patients treated with tolvaptan.

Fujioka K, Mizuno S, Ichise T, Matsui T, Hirase H, Yamaguchi M, Aoyama T, Yamagishi M, Fujino N, Kawashiri MA, Hayashi K.

Ther Adv Cardiovasc Dis. 2019 Jan-Dec;13:1753944718819064. doi: 10.1177/1753944718819064.

10.

Axl kinase drives immune checkpoint and chemokine signalling pathways in lung adenocarcinomas.

Tsukita Y, Fujino N, Miyauchi E, Saito R, Fujishima F, Itakura K, Kyogoku Y, Okutomo K, Yamada M, Okazaki T, Sugiura H, Inoue A, Okada Y, Ichinose M.

Mol Cancer. 2019 Feb 11;18(1):24. doi: 10.1186/s12943-019-0953-y.

11.

Impact of cardiac myosin light chain kinase gene mutation on development of dilated cardiomyopathy.

Hodatsu A, Fujino N, Uyama Y, Tsukamoto O, Imai-Okazaki A, Yamazaki S, Seguchi O, Konno T, Hayashi K, Kawashiri MA, Asano Y, Kitakaze M, Takashima S, Yamagishi M.

ESC Heart Fail. 2019 Apr;6(2):406-415. doi: 10.1002/ehf2.12410. Epub 2019 Jan 28.

12.

Effect of hypertrophic cardiomyopathy on the prediction of thromboembolism in patients with nonvalvular atrial fibrillation.

Tsuda T, Hayashi K, Fujino N, Konno T, Tada H, Nomura A, Tanaka Y, Sakata K, Furusho H, Takamura M, Kawashiri MA, Yamagishi M; Hokuriku-Plus AF Registry Investigators.

Heart Rhythm. 2019 Jun;16(6):829-837. doi: 10.1016/j.hrthm.2018.11.029. Epub 2018 Nov 29.

PMID:
30503962
13.

Antifungal susceptibility trend and analysis of resistance mechanism for Candida species isolated from bloodstream at a Japanese university hospital.

Sakagami T, Kawano T, Yamashita K, Yamada E, Fujino N, Kaeriyama M, Fukuda Y, Nomura N, Mitsuyama J, Suematsu H, Watanabe H, Asai N, Koizumi Y, Yamagishi Y, Mikamo H.

J Infect Chemother. 2019 Jan;25(1):34-40. doi: 10.1016/j.jiac.2018.10.007. Epub 2018 Nov 3.

PMID:
30401513
14.

Limited effects of long-term enzyme replacement therapy on the cardiac conduction system in Fabry disease.

Kaneda T, Takeda M, Suematsu T, Yamamoto R, Takata M, Higashikata T, Ino H, Tsujibata A, Hayashi K, Fujino N, Kawashiri MA.

J Cardiol Cases. 2018 Feb 9;17(5):178-181. doi: 10.1016/j.jccase.2018.01.004. eCollection 2018 May.

15.

Phenotype and Prognosis of the Lamin A/C Gene (LMNA) Mutation Carriers in Japan.

Fujino N, Hayashi K, Sakata K, Nomura A, Kawashiri MA.

Circ J. 2018 Oct 25;82(11):2699-2700. doi: 10.1253/circj.CJ-18-0954. Epub 2018 Sep 21. No abstract available.

16.

Pulmonary Lymphatic Perfusion Syndrome.

Hirano T, Fujino N, Takase K, Ota H, Tanaka R, Saito R, Suzuki A, Okutomo K, Sato T, Kageyama S, Tamada T, Sugiura H, Ichinose M.

Am J Respir Crit Care Med. 2019 Feb 15;199(4):529-530. doi: 10.1164/rccm.201806-1125IM. No abstract available.

PMID:
30240276
17.

Functional analysis of KCNH2 gene mutations of type 2 long QT syndrome in larval zebrafish using microscopy and electrocardiography.

Tanaka Y, Hayashi K, Fujino N, Konno T, Tada H, Nakanishi C, Hodatsu A, Tsuda T, Nagata Y, Teramoto R, Yoshida S, Nomura A, Kawashiri MA, Yamagishi M.

Heart Vessels. 2019 Jan;34(1):159-166. doi: 10.1007/s00380-018-1231-4. Epub 2018 Jul 25.

PMID:
30047011
18.

Correction to: Oxidative stress enhances the expression of IL-33 in human airway epithelial cells.

Aizawa H, Koarai A, Shishikura Y, Yanagisawa S, Yamaya M, Sugiura H, Numakura T, Yamada M, Ichikawa T, Fujino N, Noda M, Okada Y, Ichinose M.

Respir Res. 2018 Jun 12;19(1):116. doi: 10.1186/s12931-018-0817-9.

19.

Expression of cytochrome P450 mRNAs in Type II alveolar cells from subjects with chronic obstructive pulmonary disease.

Kamata S, Fujino N, Yamada M, Grime K, Suzuki S, Ota C, Tando Y, Okada Y, Sakurada A, Noda M, Matsuda Y, Sugiura H, Ichinose M.

Pharmacol Res Perspect. 2018 May 21;6(3):e00405. doi: 10.1002/prp2.405. eCollection 2018 Jun.

20.

Author Correction: Heart Failure Phenotypes Induced by Knockdown of DAPIT in Zebrafish: A New Insight into Mechanism of Dilated Cardiomyopathy.

Nagata Y, Yamagishi M, Konno T, Nakanishi C, Asano Y, Ito S, Nakajima Y, Seguchi O, Fujino N, Kawashiri MA, Takashima S, Kitakaze M, Hayashi K.

Sci Rep. 2018 May 14;8(1):7768. doi: 10.1038/s41598-018-26012-4.

21.

J Waves for Predicting Cardiac Events in Hypertrophic Cardiomyopathy.

Tsuda T, Hayashi K, Konno T, Sakata K, Fujita T, Hodatsu A, Nagata Y, Teramoto R, Nomura A, Tanaka Y, Furusho H, Takamura M, Kawashiri MA, Fujino N, Yamagishi M.

JACC Clin Electrophysiol. 2017 Oct;3(10):1136-1142. doi: 10.1016/j.jacep.2017.03.010. Epub 2017 Jun 28.

22.

Physical inactivity is associated with decreased growth differentiation factor 11 in chronic obstructive pulmonary disease.

Tanaka R, Sugiura H, Yamada M, Ichikawa T, Koarai A, Fujino N, Yanagisawa S, Onodera K, Numakura T, Sato K, Kyogoku Y, Sano H, Yamanaka S, Okazaki T, Tamada T, Miura M, Takahashi T, Ichinose M.

Int J Chron Obstruct Pulmon Dis. 2018 Apr 24;13:1333-1342. doi: 10.2147/COPD.S157035. eCollection 2018.

23.

TAS05567, a Novel Potent and Selective Spleen Tyrosine Kinase Inhibitor, Abrogates Immunoglobulin-Mediated Autoimmune and Allergic Reactions in Rodent Models.

Hayashi H, Kaneko R, Demizu S, Akasaka D, Tayama M, Harada T, Irie H, Ogino Y, Fujino N, Sasaki E.

J Pharmacol Exp Ther. 2018 Jul;366(1):84-95. doi: 10.1124/jpet.118.248153. Epub 2018 May 4.

PMID:
29728446
24.

Oxidative stress enhances the expression of IL-33 in human airway epithelial cells.

Aizawa H, Koarai A, Shishikura Y, Yanagisawa S, Yamaya M, Sugiura H, Numakura T, Yamada M, Ichikawa T, Fujino N, Noda M, Okada Y, Ichinose M.

Respir Res. 2018 Mar 27;19(1):52. doi: 10.1186/s12931-018-0752-9. Erratum in: Respir Res. 2018 Jun 12;19(1):116.

25.

Impact of B-Type Natriuretic Peptide Level on Risk Stratification of Thromboembolism and Death in Patients With Nonvalvular Atrial Fibrillation - The Hokuriku-Plus AF Registry.

Hayashi K, Tsuda T, Nomura A, Fujino N, Nohara A, Sakata K, Konno T, Nakanishi C, Tada H, Nagata Y, Teramoto R, Tanaka Y, Kawashiri MA, Yamagishi M; Hokuriku-Plus AF Registry Investigators.

Circ J. 2018 Apr 25;82(5):1271-1278. doi: 10.1253/circj.CJ-17-1085. Epub 2018 Mar 1.

26.

Physical interactions among flavonoid enzymes in snapdragon and torenia reveal the diversity in the flavonoid metabolon organization of different plant species.

Fujino N, Tenma N, Waki T, Ito K, Komatsuzaki Y, Sugiyama K, Yamazaki T, Yoshida S, Hatayama M, Yamashita S, Tanaka Y, Motohashi R, Denessiouk K, Takahashi S, Nakayama T.

Plant J. 2018 Apr;94(2):372-392. doi: 10.1111/tpj.13864. Epub 2018 Mar 23.

27.

Late Gadolinium Enhancement for Prediction of Mutation-Positive Hypertrophic Cardiomyopathy on the Basis of Panel-Wide Sequencing.

Teramoto R, Fujino N, Konno T, Nomura A, Nagata Y, Tsuda T, Tada H, Sakata K, Yamagishi M, Hayashi K, Kawashiri MA.

Circ J. 2018 Mar 23;82(4):1139-1148. doi: 10.1253/circj.CJ-17-1012. Epub 2018 Feb 3.

28.

Heat Failure Phenotypes Induced by Knockdown of DAPIT in Zebrafish: A New Insight into Mechanism of Dilated Cardiomyopathy.

Nagata Y, Yamagishi M, Konno T, Nakanishi C, Asano Y, Ito S, Nakajima Y, Seguchi O, Fujino N, Kawashiri MA, Takashima S, Kitakaze M, Hayashi K.

Sci Rep. 2017 Dec 12;7(1):17417. doi: 10.1038/s41598-017-17572-y. Erratum in: Sci Rep. 2018 May 14;8(1):7768.

29.

Characteristics of induced pluripotent stem cells from clinically divergent female monozygotic twins with Danon disease.

Yoshida S, Nakanishi C, Okada H, Mori M, Yokawa J, Yoshimuta T, Ohta K, Konno T, Fujino N, Kawashiri MA, Yachie A, Yamagishi M, Hayashi K.

J Mol Cell Cardiol. 2018 Jan;114:234-242. doi: 10.1016/j.yjmcc.2017.11.019. Epub 2017 Nov 23.

PMID:
29175505
30.

Overview of the 81st Annual Scientific Meeting of the Japanese Circulation Society - Cardiovascular Medicine for the Next Generation.

Fujino N, Yoshimuta T, Ichida F, Kinugawa K, Usuda K, Kitayama M, Ino H, Kawashiri MA, Tada H, Mizuno S, Hayashi K, Takemura H, Yamagishi M; all the members of the Japanese Circulation Society in Hokuriku District.

Circ J. 2017 Aug 25;81(9):1261-1267. doi: 10.1253/circj.CJ-17-0706. Epub 2017 Aug 8.

31.

Production of reactive persulfide species in chronic obstructive pulmonary disease.

Numakura T, Sugiura H, Akaike T, Ida T, Fujii S, Koarai A, Yamada M, Onodera K, Hashimoto Y, Tanaka R, Sato K, Shishikura Y, Hirano T, Yanagisawa S, Fujino N, Okazaki T, Tamada T, Hoshikawa Y, Okada Y, Ichinose M.

Thorax. 2017 Dec;72(12):1074-1083. doi: 10.1136/thoraxjnl-2016-209359. Epub 2017 Jul 19.

PMID:
28724639
32.

Phenotypic screening identifies Axl kinase as a negative regulator of an alveolar epithelial cell phenotype.

Fujino N, Kubo H, Maciewicz RA.

Lab Invest. 2017 Sep;97(9):1047-1062. doi: 10.1038/labinvest.2017.52. Epub 2017 May 29.

33.

Decrease in an anti-ageing factor, growth differentiation factor 11, in chronic obstructive pulmonary disease.

Onodera K, Sugiura H, Yamada M, Koarai A, Fujino N, Yanagisawa S, Tanaka R, Numakura T, Togo S, Sato K, Kyogoku Y, Hashimoto Y, Okazaki T, Tamada T, Kobayashi S, Yanai M, Miura M, Hoshikawa Y, Okada Y, Suzuki S, Ichinose M.

Thorax. 2017 Oct;72(10):893-904. doi: 10.1136/thoraxjnl-2016-209352. Epub 2017 Apr 28.

PMID:
28455454
34.

Diminished airway macrophage expression of the Axl receptor tyrosine kinase is associated with defective efferocytosis in asthma.

Grabiec AM, Denny N, Doherty JA, Happonen KE, Hankinson J, Connolly E, Fife ME, Fujimori T, Fujino N, Goenka A, Holden S, Tavernier G, Shah R, Cook PC, MacDonald AS, Niven RM, Dahlbäck B, Fowler SJ, Simpson A, Hussell T.

J Allergy Clin Immunol. 2017 Oct;140(4):1144-1146.e4. doi: 10.1016/j.jaci.2017.03.024. Epub 2017 Apr 12. No abstract available.

35.

Inflammatory responses in the initiation of lung repair and regeneration: their role in stimulating lung resident stem cells.

Yamada M, Fujino N, Ichinose M.

Inflamm Regen. 2016 Sep 12;36:15. doi: 10.1186/s41232-016-0020-7. eCollection 2016. Review.

36.

Serum extracellular vesicular miR-21-5p is a predictor of the prognosis in idiopathic pulmonary fibrosis.

Makiguchi T, Yamada M, Yoshioka Y, Sugiura H, Koarai A, Chiba S, Fujino N, Tojo Y, Ota C, Kubo H, Kobayashi S, Yanai M, Shimura S, Ochiya T, Ichinose M.

Respir Res. 2016 Sep 5;17(1):110. doi: 10.1186/s12931-016-0427-3.

37.

Impact of Updated Diagnostic Criteria for Long QT Syndrome on Clinical Detection of Diseased Patients: Results From a Study of Patients Carrying Gene Mutations.

Hayashi K, Konno T, Fujino N, Itoh H, Fujii Y, Imi-Hashida Y, Tada H, Tsuda T, Tanaka Y, Saito T, Ino H, Kawashiri MA, Ohta K, Horie M, Yamagishi M.

JACC Clin Electrophysiol. 2016 Jun;2(3):279-287. doi: 10.1016/j.jacep.2016.01.003. Epub 2016 Mar 23.

38.

Isolation of individual cellular components from lung tissues of patients with lymphangioleiomyomatosis.

Ando K, Fujino N, Mitani K, Ota C, Okada Y, Kondo T, Mizobuchi T, Kurihara M, Suzuki K, Hoshika Y, Ebana H, Kobayashi E, Takahashi K, Kubo H, Seyama K.

Am J Physiol Lung Cell Mol Physiol. 2016 May 15;310(10):L899-908. doi: 10.1152/ajplung.00365.2015. Epub 2016 Mar 25.

39.

Hypokalemia and the Disappearance of Giant Negative T Waves.

Konno T, Hayashi K, Fujino N, Yamagishi M.

Intern Med. 2016;55(5):545-6. doi: 10.2169/internalmedicine.55.5770. Epub 2016 Mar 1. No abstract available.

40.

Usefulness of Electrocardiographic Voltage to Determine Myocardial Fibrosis in Hypertrophic Cardiomyopathy.

Konno T, Nagata Y, Teramoto R, Fujino N, Nomura A, Tada H, Sakata K, Furusho H, Takamura M, Nakamura H, Kawashiri MA, Yamagishi M, Hayashi K.

Am J Cardiol. 2016 Feb 1;117(3):443-9. doi: 10.1016/j.amjcard.2015.11.015. Epub 2015 Nov 19.

PMID:
26705881
41.

Identification of protein-protein interactions of isoflavonoid biosynthetic enzymes with 2-hydroxyisoflavanone synthase in soybean (Glycine max (L.) Merr.).

Waki T, Yoo D, Fujino N, Mameda R, Denessiouk K, Yamashita S, Motohashi R, Akashi T, Aoki T, Ayabe S, Takahashi S, Nakayama T.

Biochem Biophys Res Commun. 2016 Jan 15;469(3):546-51. doi: 10.1016/j.bbrc.2015.12.038. Epub 2015 Dec 13.

PMID:
26694697
42.

Whole exome sequencing combined with integrated variant annotation prediction identifies a causative myosin essential light chain variant in hypertrophic cardiomyopathy.

Nomura A, Tada H, Teramoto R, Konno T, Hodatsu A, Won HH, Kathiresan S, Ino H, Fujino N, Yamagishi M, Hayashi K.

J Cardiol. 2016 Feb;67(2):133-9. doi: 10.1016/j.jjcc.2015.09.003. Epub 2015 Oct 9.

43.

Histone deacetylase inhibitor restores surfactant protein-C expression in alveolar-epithelial type II cells and attenuates bleomycin-induced pulmonary fibrosis in vivo.

Ota C, Yamada M, Fujino N, Motohashi H, Tando Y, Takei Y, Suzuki T, Takahashi T, Kamata S, Makiguchi T, Yamaya M, Kubo H.

Exp Lung Res. 2015;41(8):422-34. doi: 10.3109/01902148.2015.1060275. Epub 2015 Jul 7.

PMID:
26151196
44.

Functional Characterization of Rare Variants Implicated in Susceptibility to Lone Atrial Fibrillation.

Hayashi K, Konno T, Tada H, Tani S, Liu L, Fujino N, Nohara A, Hodatsu A, Tsuda T, Tanaka Y, Kawashiri MA, Ino H, Makita N, Yamagishi M.

Circ Arrhythm Electrophysiol. 2015 Oct;8(5):1095-104. doi: 10.1161/CIRCEP.114.002519. Epub 2015 Jun 30.

PMID:
26129877
45.

Electrocardiographic QRS Fragmentation as a Marker for Myocardial Fibrosis in Hypertrophic Cardiomyopathy.

Konno T, Hayashi K, Fujino N, Oka R, Nomura A, Nagata Y, Hodatsu A, Sakata K, Furusho H, Takamura M, Nakamura H, Kawashiri MA, Yamagishi M.

J Cardiovasc Electrophysiol. 2015 Oct;26(10):1081-7. doi: 10.1111/jce.12742. Epub 2015 Aug 11.

PMID:
26102305
46.

Right ventricular hypertrophy is associated with cardiovascular events in hypertrophic cardiomyopathy: evidence from study with magnetic resonance imaging.

Nagata Y, Konno T, Fujino N, Hodatsu A, Nomura A, Hayashi K, Nakamura H, Kawashiri MA, Yamagishi M.

Can J Cardiol. 2015 Jun;31(6):702-8. doi: 10.1016/j.cjca.2014.12.036. Epub 2015 Jan 24.

PMID:
25935883
47.

Whole exome sequencing combined with integrated variant annotation prediction identifies asymptomatic Tangier disease with compound heterozygous mutations in ABCA1 gene.

Tada H, Kawashiri MA, Nohara A, Saito R, Tanaka Y, Nomura A, Konno T, Sakata K, Fujino N, Takamura T, Inazu A, Mabuchi H, Yamagishi M, Hayashi K.

Atherosclerosis. 2015 Jun;240(2):324-9. doi: 10.1016/j.atherosclerosis.2015.04.003. Epub 2015 Apr 7.

PMID:
25875382
48.

The Axl receptor tyrosine kinase is a discriminator of macrophage function in the inflamed lung.

Fujimori T, Grabiec AM, Kaur M, Bell TJ, Fujino N, Cook PC, Svedberg FR, MacDonald AS, Maciewicz RA, Singh D, Hussell T.

Mucosal Immunol. 2015 Sep;8(5):1021-1030. doi: 10.1038/mi.2014.129. Epub 2015 Jan 21.

49.

Increased extent of myocardial fibrosis in genotyped hypertrophic cardiomyopathy with ventricular tachyarrhythmias.

Fujita T, Konno T, Yokawa J, Masuta E, Nagata Y, Fujino N, Funada A, Hodatsu A, Kawashiri MA, Yamagishi M, Hayashi K.

J Cardiol. 2015 Jul;66(1):63-8. doi: 10.1016/j.jjcc.2014.10.002. Epub 2014 Nov 14.

50.

Fragmented QRS predicts heart failure progression in patients with hypertrophic cardiomyopathy.

Nomura A, Konno T, Fujita T, Tanaka Y, Nagata Y, Tsuda T, Hodatsu A, Sakata K, Nakamura H, Kawashiri MA, Fujino N, Yamagishi M, Hayashi K.

Circ J. 2015;79(1):136-43. doi: 10.1253/circj.CJ-14-0822. Epub 2014 Nov 7.

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