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Items: 1 to 50 of 297

1.

Fused in sarcoma silences HIV gene transcription and maintains viral latency through suppressing AFF4 gene activation.

Krasnopolsky S, Marom L, Victor RA, Kuzmina A, Schwartz JC, Fujinaga K, Taube R.

Retrovirology. 2019 Jun 25;16(1):16. doi: 10.1186/s12977-019-0478-x.

2.

Cardiac tamponade due to rupture of a giant coronary artery aneurysm with a coronary arteriovenous fistula: a case report.

Shomura Y, Mizumoto T, Fujinaga K, Sawada Y, Ito H, Teranishi S.

Surg Case Rep. 2019 Mar 12;5(1):40. doi: 10.1186/s40792-019-0597-6.

3.

P-TEFb Activation by RBM7 Shapes a Pro-survival Transcriptional Response to Genotoxic Stress.

Bugai A, Quaresma AJC, Friedel CC, Lenasi T, Düster R, Sibley CR, Fujinaga K, Kukanja P, Hennig T, Blasius M, Geyer M, Ule J, Dölken L, Barborič M.

Mol Cell. 2019 Apr 18;74(2):254-267.e10. doi: 10.1016/j.molcel.2019.01.033. Epub 2019 Feb 26.

4.

HEXIM1-Tat chimera inhibits HIV-1 replication.

Leoz M, Kukanja P, Luo Z, Huang F, Cary DC, Peterlin BM, Fujinaga K.

PLoS Pathog. 2018 Nov 5;14(11):e1007402. doi: 10.1371/journal.ppat.1007402. eCollection 2018 Nov.

5.

HIV Tat/P-TEFb Interaction: A Potential Target for Novel Anti-HIV Therapies.

Asamitsu K, Fujinaga K, Okamoto T.

Molecules. 2018 Apr 17;23(4). pii: E933. doi: 10.3390/molecules23040933. Review.

6.

The tremendous potential of deep-sea mud as a source of rare-earth elements.

Takaya Y, Yasukawa K, Kawasaki T, Fujinaga K, Ohta J, Usui Y, Nakamura K, Kimura JI, Chang Q, Hamada M, Dodbiba G, Nozaki T, Iijima K, Morisawa T, Kuwahara T, Ishida Y, Ichimura T, Kitazume M, Fujita T, Kato Y.

Sci Rep. 2018 Apr 10;8(1):5763. doi: 10.1038/s41598-018-23948-5.

7.

Bromodomain-containing protein 4-independent transcriptional activation by autoimmune regulator (AIRE) and NF-κB.

Huang F, Shao W, Fujinaga K, Peterlin BM.

J Biol Chem. 2018 Apr 6;293(14):4993-5004. doi: 10.1074/jbc.RA117.001518. Epub 2018 Feb 20.

8.

Susceptibility of Human Endogenous Retrovirus Type K to Reverse Transcriptase Inhibitors.

Contreras-Galindo R, Dube D, Fujinaga K, Kaplan MH, Markovitz DM.

J Virol. 2017 Nov 14;91(23). pii: e01309-17. doi: 10.1128/JVI.01309-17. Print 2017 Dec 1.

9.

Earth system feedback statistically extracted from the Indian Ocean deep-sea sediments recording Eocene hyperthermals.

Yasukawa K, Nakamura K, Fujinaga K, Ikehara M, Kato Y.

Sci Rep. 2017 Sep 12;7(1):11304. doi: 10.1038/s41598-017-11470-z.

10.

Neuroprotective effect of pressure-oriented flow regulation and pH-stat management in selective antegrade brain perfusion during total aortic arch repair.

Ito H, Mizumoto T, Sawada Y, Fujinaga K, Tempaku H, Yamamoto Y, Tsutsui K, Shimpo H.

Interact Cardiovasc Thorac Surg. 2017 Oct 1;25(4):565-570. doi: 10.1093/icvts/ivx182.

PMID:
28637170
11.

Hili Inhibits HIV Replication in Activated T Cells.

Peterlin BM, Liu P, Wang X, Cary D, Shao W, Leoz M, Hong T, Pan T, Fujinaga K.

J Virol. 2017 May 12;91(11). pii: e00237-17. doi: 10.1128/JVI.00237-17. Print 2017 Jun 1.

12.

Determinants of recurrent tricuspid regurgitation following tricuspid valve annuloplasty during mitral valve surgery.

Ito H, Mizumoto T, Sawada Y, Fujinaga K, Tempaku H, Shimpo H.

J Card Surg. 2017 Apr;32(4):237-244. doi: 10.1111/jocs.13117. Epub 2017 Mar 8.

PMID:
28273682
13.

Euphorbia Kansui Reactivates Latent HIV.

Cary DC, Fujinaga K, Peterlin BM.

PLoS One. 2016 Dec 15;11(12):e0168027. doi: 10.1371/journal.pone.0168027. eCollection 2016.

14.

Efficacy of Tolvaptan on Fluid Management After Cardiovascular Surgery Using Cardiopulmonary Bypass.

Ito H, Mizumoto T, Tempaku H, Fujinaga K, Sawada Y, Shimpo H.

J Cardiothorac Vasc Anesth. 2016 Dec;30(6):1471-1478. doi: 10.1053/j.jvca.2016.06.013. Epub 2016 Jun 15.

PMID:
27591907
15.

Tracking the spatiotemporal variations of statistically independent components involving enrichment of rare-earth elements in deep-sea sediments.

Yasukawa K, Nakamura K, Fujinaga K, Iwamori H, Kato Y.

Sci Rep. 2016 Jul 22;6:29603. doi: 10.1038/srep29603.

16.

Measuring Attitudes Toward Nursing Safety Violations.

Adachi Y, Usui S, Nakagami-Yamaguchi E, Fujinaga K, Park K, Nakamura K, Nakatani T.

Percept Mot Skills. 2016 Feb;122(1):5-26. doi: 10.1177/0031512515627070. Epub 2016 Feb 1.

PMID:
27420303
17.

Bolide impact triggered the Late Triassic extinction event in equatorial Panthalassa.

Onoue T, Sato H, Yamashita D, Ikehara M, Yasukawa K, Fujinaga K, Kato Y, Matsuoka A.

Sci Rep. 2016 Jul 8;6:29609. doi: 10.1038/srep29609.

18.

FBXO3 Protein Promotes Ubiquitylation and Transcriptional Activity of AIRE (Autoimmune Regulator).

Shao W, Zumer K, Fujinaga K, Peterlin BM.

J Biol Chem. 2016 Aug 19;291(34):17953-63. doi: 10.1074/jbc.M116.724401. Epub 2016 Jun 30.

19.

Influence of Angiotensin-converting Enzyme Genetic Polymorphism on Late Renal Dysfunction After Adult-to-adult Living-donor Liver Transplantation.

Matsui T, Usui M, Fujinaga K, Nakatani K, Iizawa Y, Kato H, Tanemura A, Murata Y, Azumi Y, Kuriyama N, Kishiwada M, Mizuno S, Sakurai H, Isaji S.

Transplant Proc. 2016 May;48(4):1184-9. doi: 10.1016/j.transproceed.2016.02.014.

PMID:
27320583
20.

Emergency Off-Pump Coronary Artery Bypass Graft Surgery for Patients on Preoperative Intraaortic Balloon Pump.

Ito H, Mizumoto T, Tempaku H, Fujinaga K, Sawada Y, Teranishi S, Shimpo H.

Ann Thorac Surg. 2016 Sep;102(3):821-828. doi: 10.1016/j.athoracsur.2016.02.088. Epub 2016 May 4.

PMID:
27154155
21.

Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma.

Tan JL, Fogley RD, Flynn RA, Ablain J, Yang S, Saint-André V, Fan ZP, Do BT, Laga AC, Fujinaga K, Santoriello C, Greer CB, Kim YJ, Clohessy JG, Bothmer A, Pandell N, Avagyan S, Brogie JE, van Rooijen E, Hagedorn EJ, Shyh-Chang N, White RM, Price DH, Pandolfi PP, Peterlin BM, Zhou Y, Kim TH, Asara JM, Chang HY, Young RA, Zon LI.

Mol Cell. 2016 Apr 7;62(1):34-46. doi: 10.1016/j.molcel.2016.03.013.

22.

The two sides of Tat.

Barboric M, Fujinaga K.

Elife. 2016 Jan 19;5:e12686. doi: 10.7554/eLife.12686.

23.

[Pulmonary Arterioplasty with Autologous Pericardial Patch for Lung Cancer].

Shomura Y, Fujinaga K, Takahashi Y, Hamakawa H, Fujii K, Teranishi S, Itoh H, Sawada Y, Mizumoto T.

Kyobu Geka. 2015 Dec;68(13):1041-4. Japanese.

PMID:
26759941
24.

Molecular mechanisms of HIV latency.

Cary DC, Fujinaga K, Peterlin BM.

J Clin Invest. 2016 Feb;126(2):448-54. doi: 10.1172/JCI80565. Epub 2016 Jan 5. Review.

25.

CDK11 in TREX/THOC Regulates HIV mRNA 3' End Processing.

Pak V, Eifler TT, Jäger S, Krogan NJ, Fujinaga K, Peterlin BM.

Cell Host Microbe. 2015 Nov 11;18(5):560-70. doi: 10.1016/j.chom.2015.10.012.

26.

An In-Depth Comparison of Latency-Reversing Agent Combinations in Various In Vitro and Ex Vivo HIV-1 Latency Models Identified Bryostatin-1+JQ1 and Ingenol-B+JQ1 to Potently Reactivate Viral Gene Expression.

Darcis G, Kula A, Bouchat S, Fujinaga K, Corazza F, Ait-Ammar A, Delacourt N, Melard A, Kabeya K, Vanhulle C, Van Driessche B, Gatot JS, Cherrier T, Pianowski LF, Gama L, Schwartz C, Vila J, Burny A, Clumeck N, Moutschen M, De Wit S, Peterlin BM, Rouzioux C, Rohr O, Van Lint C.

PLoS Pathog. 2015 Jul 30;11(7):e1005063. doi: 10.1371/journal.ppat.1005063. eCollection 2015 Jul.

27.

Postmortem diagnosis of massive gastrointestinal bleeding in a patient with aberrant right subclavian artery-esophageal fistula.

Watanabe M, Suzuki K, Fujinaga K, Yamamoto A, Fujioka M, Katayama N, Imai H.

Acute Med Surg. 2015 Jul 14;3(2):139-142. doi: 10.1002/ams2.136. eCollection 2016 Apr.

28.

Visualization of positive transcription elongation factor b (P-TEFb) activation in living cells.

Fujinaga K, Luo Z, Schaufele F, Peterlin BM.

J Biol Chem. 2015 Jan 16;290(3):1829-36. doi: 10.1074/jbc.M114.605816. Epub 2014 Dec 9.

29.

Cyclin-dependent kinase 12 increases 3' end processing of growth factor-induced c-FOS transcripts.

Eifler TT, Shao W, Bartholomeeusen K, Fujinaga K, Jäger S, Johnson JR, Luo Z, Krogan NJ, Peterlin BM.

Mol Cell Biol. 2015 Jan;35(2):468-78. doi: 10.1128/MCB.01157-14. Epub 2014 Nov 10.

30.
31.

[A patient with descending necrotizing mediastinitis successfully treated by cervical, transthoracic, and mediastinoscopic drainage].

Shomura Y, Takahashi Y, Fujinaga K, Komatsu T, Mizumoto T.

Kyobu Geka. 2014 Apr;67(4):323-7. Japanese.

PMID:
24917164
32.

Hypertension and hepatitis C virus infection are strong risk factors for developing late renal dysfunction after living donor liver transplantation: significance of renal biopsy.

Fujinaga K, Usui M, Yamamoto N, Ishikawa E, Nakatani A, Kishiwada M, Mizuno S, Sakurai H, Tabata M, Isaji S.

Transplant Proc. 2014 Apr;46(3):804-10. doi: 10.1016/j.transproceed.2013.11.103.

PMID:
24767353
33.

Negative elongation factor is required for the maintenance of proviral latency but does not induce promoter-proximal pausing of RNA polymerase II on the HIV long terminal repeat.

Jadlowsky JK, Wong JY, Graham AC, Dobrowolski C, Devor RL, Adams MD, Fujinaga K, Karn J.

Mol Cell Biol. 2014 Jun;34(11):1911-28. doi: 10.1128/MCB.01013-13. Epub 2014 Mar 17.

34.

Release of positive transcription elongation factor b (P-TEFb) from 7SK small nuclear ribonucleoprotein (snRNP) activates hexamethylene bisacetamide-inducible protein (HEXIM1) transcription.

Liu P, Xiang Y, Fujinaga K, Bartholomeeusen K, Nilson KA, Price DH, Peterlin BM.

J Biol Chem. 2014 Apr 4;289(14):9918-25. doi: 10.1074/jbc.M113.539015. Epub 2014 Feb 10.

35.

Histone deacetylase inhibitors (HDACis) that release the positive transcription elongation factor b (P-TEFb) from its inhibitory complex also activate HIV transcription.

Bartholomeeusen K, Fujinaga K, Xiang Y, Peterlin BM.

J Biol Chem. 2013 May 17;288(20):14400-7. doi: 10.1074/jbc.M113.464834. Epub 2013 Mar 28.

36.

Bromodomain and extra-terminal (BET) bromodomain inhibition activate transcription via transient release of positive transcription elongation factor b (P-TEFb) from 7SK small nuclear ribonucleoprotein.

Bartholomeeusen K, Xiang Y, Fujinaga K, Peterlin BM.

J Biol Chem. 2012 Oct 19;287(43):36609-16. doi: 10.1074/jbc.M112.410746. Epub 2012 Sep 5. Erratum in: J Biol Chem. 2013 Apr 26;288(17):12214.

37.

PKC phosphorylates HEXIM1 and regulates P-TEFb activity.

Fujinaga K, Barboric M, Li Q, Luo Z, Price DH, Peterlin BM.

Nucleic Acids Res. 2012 Oct;40(18):9160-70. doi: 10.1093/nar/gks682. Epub 2012 Jul 20.

38.

[Recurrent mediastinal desmoid tumor treated by surgical resection ; report of a case].

Fujinaga K, Sakamoto S, Sawada Y, Tanaka J, Mizumoto T.

Kyobu Geka. 2012 Mar;65(3):252-4. Japanese.

PMID:
22374605
39.

Functional characterization of a human cyclin T1 mutant reveals a different binding surface for Tat and HEXIM1.

Kuzmina A, Hadad U, Fujinaga K, Taube R.

Virology. 2012 May 10;426(2):152-61. doi: 10.1016/j.virol.2012.01.033. Epub 2012 Feb 18.

40.

Activation of P-TEFb at sites of dual HIV/TB infection, and inhibition of MTB-induced HIV transcriptional activation by the inhibitor of CDK9, Indirubin-3'-monoxime.

Toossi Z, Wu M, Hirsch CS, Mayanja-Kizza H, Baseke J, Aung H, Canaday DH, Fujinaga K.

AIDS Res Hum Retroviruses. 2012 Feb;28(2):182-7. doi: 10.1089/AID.2010.0211. Epub 2011 May 6.

41.

HIV-1 inhibits autophagy in bystander macrophage/monocytic cells through Src-Akt and STAT3.

Van Grol J, Subauste C, Andrade RM, Fujinaga K, Nelson J, Subauste CS.

PLoS One. 2010 Jul 22;5(7):e11733. doi: 10.1371/journal.pone.0011733.

42.

Cyclin T1 stabilizes expression levels of HIV-1 Tat in cells.

Imai K, Asamitsu K, Victoriano AF, Cueno ME, Fujinaga K, Okamoto T.

FEBS J. 2009 Dec;276(23):7124-33. doi: 10.1111/j.1742-4658.2009.07424.x.

43.

Dominant negative mutant cyclin T1 proteins that inhibit HIV transcription by forming a kinase inactive complex with Tat.

Jadlowsky JK, Nojima M, Okamoto T, Fujinaga K.

J Gen Virol. 2008 Nov;89(Pt 11):2783-7. doi: 10.1099/vir.0.2008/002857-0.

PMID:
18931076
44.

Hemodynamic performance of the Edwards Prima Plus stentless valve at 1 year.

Tanaka K, Kinoshita T, Fujinaga K, Kanemitsu S, Tanaka J, Suzuki H, Tokui T.

Gen Thorac Cardiovasc Surg. 2008 Sep;56(9):441-5. doi: 10.1007/s11748-008-0286-z. Epub 2008 Sep 13.

PMID:
18791668
45.

HEXIM1 regulates 17beta-estradiol/estrogen receptor-alpha-mediated expression of cyclin D1 in mammary cells via modulation of P-TEFb.

Ogba N, Chaplin LJ, Doughman YQ, Fujinaga K, Montano MM.

Cancer Res. 2008 Sep 1;68(17):7015-24. doi: 10.1158/0008-5472.CAN-08-0814.

46.

The positive transcription elongation factor b is an essential cofactor for the activation of transcription by myocyte enhancer factor 2.

Nojima M, Huang Y, Tyagi M, Kao HY, Fujinaga K.

J Mol Biol. 2008 Oct 3;382(2):275-87. doi: 10.1016/j.jmb.2008.07.017. Epub 2008 Jul 16.

47.

Dominant negative mutant cyclin T1 proteins inhibit HIV transcription by specifically degrading Tat.

Jadlowsky JK, Nojima M, Schulte A, Geyer M, Okamoto T, Fujinaga K.

Retrovirology. 2008 Jul 11;5:63. doi: 10.1186/1742-4690-5-63.

48.

[Marked hypoalbuminemia caused by Capillaria philippinensis].

Sakabe S, Fujinaga K, Tsuji N, Ito N, Umino A, Taniguchi M, Mizutani M, Tamaki S, Tanigawa M, Tsuji K, Sato H.

Nihon Naika Gakkai Zasshi. 2007 Oct 10;96(10):2282-3. Japanese. No abstract available.

PMID:
18044166
49.

Locally applied cilostazol suppresses neointimal hyperplasia and medial thickening in a vein graft model.

Yamamoto K, Onoda K, Sawada Y, Fujinaga K, Imanaka-Yoshida K, Yoshida T, Shimpo H.

Ann Thorac Cardiovasc Surg. 2007 Oct;13(5):322-30.

PMID:
17954989
50.

[Infusion therapy at outpatient clinic in chronic end-stage heart failure].

Nishi K, Sato Y, Miyamoto T, Taniguchi R, Matsuoka T, Kuwabara Y, Isoda K, Yamane K, Hatakenaka T, Fujinaga K, Fujiwara H, Takatsu Y.

J Cardiol. 2007 May;49(5):251-8. Japanese.

PMID:
17552290

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