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Items: 1 to 50 of 79

1.

Synthesis and biological evaluation of novel imidazole nucleosides as potential anti-dengue virus agents.

Okano Y, Saito-Tarashima N, Kurosawa M, Iwabu A, Ota M, Watanabe T, Kato F, Hishiki T, Fujimuro M, Minakawa N.

Bioorg Med Chem. 2019 Jun 1;27(11):2181-2186. doi: 10.1016/j.bmc.2019.04.015. Epub 2019 Apr 8.

PMID:
31003866
2.

Capsaicin Induces Apoptosis in KSHV-Positive Primary Effusion Lymphoma by Suppressing ERK and p38 MAPK Signaling and IL-6 Expression.

Moriguchi M, Watanabe T, Kadota A, Fujimuro M.

Front Oncol. 2019 Feb 19;9:83. doi: 10.3389/fonc.2019.00083. eCollection 2019.

3.

[Replication Machinery of Kaposi's Sarcoma-associated Herpesvirus and Drug Discovery Research].

Watanabe T, Fujimuro M.

Yakugaku Zasshi. 2019;139(1):69-73. doi: 10.1248/yakushi.18-00164-2. Review. Japanese.

4.
5.

Signal Transduction Pathways Associated with KSHV-Related Tumors.

Watanabe T, Sugimoto A, Hosokawa K, Fujimuro M.

Adv Exp Med Biol. 2018;1045:321-355. doi: 10.1007/978-981-10-7230-7_15. Review.

PMID:
29896674
6.

KSHV episomes reveal dynamic chromatin loop formation with domain-specific gene regulation.

Campbell M, Watanabe T, Nakano K, Davis RR, Lyu Y, Tepper CG, Durbin-Johnson B, Fujimuro M, Izumiya Y.

Nat Commun. 2018 Jan 4;9(1):49. doi: 10.1038/s41467-017-02089-9.

7.

New diterpenes from Nigella damascena seeds and their antiviral activities against herpes simplex virus type-1.

Ogawa K, Nakamura S, Hosokawa K, Ishimaru H, Saito N, Ryu K, Fujimuro M, Nakashima S, Matsuda H.

J Nat Med. 2018 Mar;72(2):439-447. doi: 10.1007/s11418-017-1166-6. Epub 2017 Dec 29.

PMID:
29288328
8.

Arctigenin induces the apoptosis of primary effusion lymphoma cells under conditions of glucose deprivation.

Baba Y, Shigemi Z, Hara N, Moriguchi M, Ikeda M, Watanabe T, Fujimuro M.

Int J Oncol. 2018 Feb;52(2):505-517. doi: 10.3892/ijo.2017.4215. Epub 2017 Dec 1.

PMID:
29207179
9.

Kaposi's sarcoma-associated herpesvirus ORF34 is essential for late gene expression and virus production.

Nishimura M, Watanabe T, Yagi S, Yamanaka T, Fujimuro M.

Sci Rep. 2017 Mar 23;7(1):329. doi: 10.1038/s41598-017-00401-7.

10.

Methylseleninic acid and sodium selenite induce severe ER stress and subsequent apoptosis through UPR activation in PEL cells.

Shigemi Z, Manabe K, Hara N, Baba Y, Hosokawa K, Kagawa H, Watanabe T, Fujimuro M.

Chem Biol Interact. 2017 Mar 25;266:28-37. doi: 10.1016/j.cbi.2017.01.027. Epub 2017 Feb 1.

PMID:
28161410
11.

The dynamics of histone H2A ubiquitination in HeLa cells exposed to rapamycin, ethanol, hydroxyurea, ER stress, heat shock and DNA damage.

Nakata S, Watanabe T, Nakagawa K, Takeda H, Ito A, Fujimuro M.

Biochem Biophys Res Commun. 2016 Mar 25;472(1):46-52. doi: 10.1016/j.bbrc.2016.02.057. Epub 2016 Feb 17.

PMID:
26898798
12.

Repression of Wnt/β-catenin response elements by p63 (TP63).

Katoh I, Fukunishi N, Fujimuro M, Kasai H, Moriishi K, Hata R, Kurata S.

Cell Cycle. 2016;15(5):699-710. doi: 10.1080/15384101.2016.1148837.

13.

Effects of ER stress on unfolded protein responses, cell survival, and viral replication in primary effusion lymphoma.

Shigemi Z, Baba Y, Hara N, Matsuhiro J, Kagawa H, Watanabe T, Fujimuro M.

Biochem Biophys Res Commun. 2016 Jan 15;469(3):565-72. doi: 10.1016/j.bbrc.2015.12.032. Epub 2015 Dec 12.

PMID:
26692493
14.

Diallyl trisulfide induces apoptosis by suppressing NF-κB signaling through destabilization of TRAF6 in primary effusion lymphoma.

Shigemi Z, Furukawa Y, Hosokawa K, Minami S, Matsuhiro J, Nakata S, Watanabe T, Kagawa H, Nakagawa K, Takeda H, Fujimuro M.

Int J Oncol. 2016 Jan;48(1):293-304. doi: 10.3892/ijo.2015.3247. Epub 2015 Nov 17.

PMID:
26647777
15.

Pyrrolidinium fullerene induces apoptosis by activation of procaspase-9 via suppression of Akt in primary effusion lymphoma.

Watanabe T, Nakamura S, Ono T, Ui S, Yagi S, Kagawa H, Watanabe H, Ohe T, Mashino T, Fujimuro M.

Biochem Biophys Res Commun. 2014 Aug 15;451(1):93-100. doi: 10.1016/j.bbrc.2014.07.068. Epub 2014 Jul 22.

PMID:
25063029
16.

Sangivamycin induces apoptosis by suppressing Erk signaling in primary effusion lymphoma cells.

Wakao K, Watanabe T, Takadama T, Ui S, Shigemi Z, Kagawa H, Higashi C, Ohga R, Taira T, Fujimuro M.

Biochem Biophys Res Commun. 2014 Feb 7;444(2):135-40. doi: 10.1016/j.bbrc.2014.01.017. Epub 2014 Jan 14.

PMID:
24434142
17.

Notch-Nrf2 axis: regulation of Nrf2 gene expression and cytoprotection by notch signaling.

Wakabayashi N, Skoko JJ, Chartoumpekis DV, Kimura S, Slocum SL, Noda K, Palliyaguru DL, Fujimuro M, Boley PA, Tanaka Y, Shigemura N, Biswal S, Yamamoto M, Kensler TW.

Mol Cell Biol. 2014 Feb;34(4):653-63. doi: 10.1128/MCB.01408-13. Epub 2013 Dec 2.

18.

Hyrtioreticulins A-E, indole alkaloids inhibiting the ubiquitin-activating enzyme, from the marine sponge Hyrtios reticulatus.

Yamanokuchi R, Imada K, Miyazaki M, Kato H, Watanabe T, Fujimuro M, Saeki Y, Yoshinaga S, Terasawa H, Iwasaki N, Rotinsulu H, Losung F, Mangindaan RE, Namikoshi M, de Voogd NJ, Yokosawa H, Tsukamoto S.

Bioorg Med Chem. 2012 Jul 15;20(14):4437-42. doi: 10.1016/j.bmc.2012.05.044. Epub 2012 May 24.

PMID:
22695182
19.

The effects of heat shock protein 90 inhibitors on apoptosis and viral replication in primary effusion lymphoma cells.

Higashi C, Saji C, Yamada K, Kagawa H, Ohga R, Taira T, Fujimuro M.

Biol Pharm Bull. 2012;35(5):725-30.

20.

The Ubiquitin System and Kaposi's Sarcoma-Associated Herpesvirus.

Ashizawa A, Higashi C, Masuda K, Ohga R, Taira T, Fujimuro M.

Front Microbiol. 2012 Feb 23;3:66. doi: 10.3389/fmicb.2012.00066. eCollection 2012.

21.

Proteasome inhibitors induce apoptosis and reduce viral replication in primary effusion lymphoma cells.

Saji C, Higashi C, Niinaka Y, Yamada K, Noguchi K, Fujimuro M.

Biochem Biophys Res Commun. 2011 Dec 2;415(4):573-8. doi: 10.1016/j.bbrc.2011.10.107. Epub 2011 Oct 31.

PMID:
22074820
22.

Regulation of inducible nitric-oxide synthase by the SPRY domain- and SOCS box-containing proteins.

Nishiya T, Matsumoto K, Maekawa S, Kajita E, Horinouchi T, Fujimuro M, Ogasawara K, Uehara T, Miwa S.

J Biol Chem. 2011 Mar 18;286(11):9009-19. doi: 10.1074/jbc.M110.190678. Epub 2011 Jan 3.

23.

Silencing of autocrine motility factor induces mesenchymal-to-epithelial transition and suppression of osteosarcoma pulmonary metastasis.

Niinaka Y, Harada K, Fujimuro M, Oda M, Haga A, Hosoki M, Uzawa N, Arai N, Yamaguchi S, Yamashiro M, Raz A.

Cancer Res. 2010 Nov 15;70(22):9483-93. doi: 10.1158/0008-5472.CAN-09-3880. Epub 2010 Oct 26.

24.

Functional availability of gamma-herpesvirus K-cyclin is regulated by cellular CDK6 and p16INK4a.

Yoshioka H, Noguchi K, Katayama K, Mitsuhashi J, Yamagoe S, Fujimuro M, Sugimoto Y.

Biochem Biophys Res Commun. 2010 Apr 16;394(4):1000-5. doi: 10.1016/j.bbrc.2010.03.110. Epub 2010 Mar 21.

PMID:
20331971
25.

BS69 cooperates with TRAF3 in the regulation of Epstein-Barr virus-derived LMP1/CTAR1-induced NF-kappaB activation.

Ikeda O, Miyasaka Y, Yoshida R, Mizushima A, Oritani K, Sekine Y, Kuroda M, Yasui T, Fujimuro M, Muromoto R, Nanbo A, Matsuda T.

FEBS Lett. 2010 Mar 5;584(5):865-72. doi: 10.1016/j.febslet.2010.01.060. Epub 2010 Feb 5.

26.

9-(2-C-Cyano-2-deoxy-beta-D-arabino-pentofuranosyl)guanine, a potential antitumor agent against B-lymphoma infected with Kaposi's sarcoma-associated herpesvirus.

Ichikawa S, Otawa M, Teishikata Y, Yamada K, Fujimuro M, Yokosawa H, Matsuda A.

Nucleic Acids Symp Ser (Oxf). 2009;(53):95-6. doi: 10.1093/nass/nrp048.

PMID:
19749277
27.

An unusual case of chronic relapsing tetanus associated with mandibular osteomyelitis.

Wakasaya Y, Watanabe M, Tomiyama M, Suzuki C, Jackson M, Fujimuro M, Kimura T, Seino Y, Kawarabayashi T, Yamamoto-Watanabe Y, Matsubara E, Shirahama I, Takamura A, Nakahata N, Shoji M.

Intern Med. 2009;48(15):1311-3. Epub 2009 Aug 3.

28.
29.

BS69 negatively regulates the canonical NF-kappaB activation induced by Epstein-Barr virus-derived LMP1.

Ikeda O, Sekine Y, Mizushima A, Oritani K, Yasui T, Fujimuro M, Muromoto R, Nanbo A, Matsuda T.

FEBS Lett. 2009 May 19;583(10):1567-74. doi: 10.1016/j.febslet.2009.04.022. Epub 2009 Apr 18.

30.

Epstein-Barr virus-derived EBNA2 regulates STAT3 activation.

Muromoto R, Ikeda O, Okabe K, Togi S, Kamitani S, Fujimuro M, Harada S, Oritani K, Matsuda T.

Biochem Biophys Res Commun. 2009 Jan 16;378(3):439-43. doi: 10.1016/j.bbrc.2008.11.053. Epub 2008 Nov 24.

31.

Nuclear DISC1 regulates CRE-mediated gene transcription and sleep homeostasis in the fruit fly.

Sawamura N, Ando T, Maruyama Y, Fujimuro M, Mochizuki H, Honjo K, Shimoda M, Toda H, Sawamura-Yamamoto T, Makuch LA, Hayashi A, Ishizuka K, Cascella NG, Kamiya A, Ishida N, Tomoda T, Hai T, Furukubo-Tokunaga K, Sawa A.

Mol Psychiatry. 2008 Dec;13(12):1138-48, 1069. doi: 10.1038/mp.2008.101. Epub 2008 Sep 2.

32.

[Regulations of gene expression and the ubiquitin-dependent pathway by human herpesvirus 8].

Fujimuro M, Yokosawa H.

Tanpakushitsu Kakusan Koso. 2007 Aug;52(10 Suppl):1113-20. Review. Japanese. No abstract available.

PMID:
17824226
33.

Molecular piracy: manipulation of the ubiquitin system by Kaposi's sarcoma-associated herpesvirus.

Fujimuro M, Hayward SD, Yokosawa H.

Rev Med Virol. 2007 Nov-Dec;17(6):405-22. Review.

PMID:
17688306
34.

Transient activation of transgene expression by hydrodynamics-based injection may cause rapid decrease in plasmid DNA expression.

Ochiai H, Fujimuro M, Yokosawa H, Harashima H, Kamiya H.

Gene Ther. 2007 Aug;14(15):1152-9. Epub 2007 May 24.

35.

[Kaposi's sarcoma-associated herpesvirus and mechanisms of oncogenesis].

Fujimuro M.

Uirusu. 2006 Dec;56(2):209-18. Review. Japanese.

36.

9-(2-C-Cyano-2-deoxy-beta-D-arabino-pentofuranosyl)guanine, a potential antitumor agent against B-lymphoma infected with Kaposi's sarcoma-associated herpesvirus.

Ohtawa M, Ichikawa S, Teishikata Y, Fujimuro M, Yokosawa H, Matsuda A.

J Med Chem. 2007 May 3;50(9):2007-10. Epub 2007 Apr 3.

PMID:
17402726
37.

Epidemiology of Epstein-Barr virus, cytomegalovirus, and Kaposi's sarcoma-associated herpesvirus infections in peripheral blood leukocytes revealed by a multiplex PCR assay.

Nishiwaki M, Fujimuro M, Teishikata Y, Inoue H, Sasajima H, Nakaso K, Nakashima K, Sadanari H, Yamamoto T, Fujiwara Y, Ogawa N, Yokosawa H.

J Med Virol. 2006 Dec;78(12):1635-42.

PMID:
17063511
38.

Apoptotic effect of ganciclovir on primary effusion lymphoma cells infected with Kaposi's sarcoma-associated herpesvirus.

Fujimuro M, Inoue H, Teishikata Y, Ishida Y, Yokosawa H.

Nucleosides Nucleotides Nucleic Acids. 2006;25(4-6):635-45.

PMID:
16838851
39.

Notch and Wnt signaling: mimicry and manipulation by gamma herpesviruses.

Hayward SD, Liu J, Fujimuro M.

Sci STKE. 2006 May 16;2006(335):re4. Review.

PMID:
16705130
40.

[Kaposi's sarcoma-associated herpesvirus and cell signaling].

Fujimuro M.

Nihon Rinsho. 2006 Mar;64 Suppl 3:558-63. Review. Japanese. No abstract available.

PMID:
16615534
41.

Physical and functional interactions between STAT3 and Kaposi's sarcoma-associated herpesvirus-encoded LANA.

Muromoto R, Okabe K, Fujimuro M, Sugiyama K, Yokosawa H, Seya T, Matsuda T.

FEBS Lett. 2006 Jan 9;580(1):93-8. Epub 2005 Dec 6.

43.

Involvement of polyubiquitin chains via specific chain linkages in stress response in mammalian cells.

Fujimuro M, Nishiya T, Nomura Y, Yokosawa H.

Biol Pharm Bull. 2005 Dec;28(12):2315-8.

44.

Multiplex PCR-based DNA array for simultaneous detection of three human herpesviruses, EVB, CMV and KSHV.

Fujimuro M, Nakaso K, Nakashima K, Sadanari H, Hisanori I, Teishikata Y, Hayward SD, Yokosawa H.

Exp Mol Pathol. 2006 Apr;80(2):124-31. Epub 2005 Nov 18.

PMID:
16298362
45.
46.

p53 mediates cellular dysfunction and behavioral abnormalities in Huntington's disease.

Bae BI, Xu H, Igarashi S, Fujimuro M, Agrawal N, Taya Y, Hayward SD, Moran TH, Montell C, Ross CA, Snyder SH, Sawa A.

Neuron. 2005 Jul 7;47(1):29-41.

47.

S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding.

Hara MR, Agrawal N, Kim SF, Cascio MB, Fujimuro M, Ozeki Y, Takahashi M, Cheah JH, Tankou SK, Hester LD, Ferris CD, Hayward SD, Snyder SH, Sawa A.

Nat Cell Biol. 2005 Jul;7(7):665-74. Epub 2005 Jun 12.

PMID:
15951807
48.

Himeic acid A: a new ubiquitin-activating enzyme inhibitor isolated from a marine-derived fungus, Aspergillus sp.

Tsukamoto S, Hirota H, Imachi M, Fujimuro M, Onuki H, Ohta T, Yokosawa H.

Bioorg Med Chem Lett. 2005 Jan 3;15(1):191-4.

PMID:
15582438
49.

Manipulation of glycogen-synthase kinase-3 activity in KSHV-associated cancers.

Fujimuro M, Hayward SD.

J Mol Med (Berl). 2004 Apr;82(4):223-31. Epub 2004 Jan 9. Review.

PMID:
14991150
50.

[The role of Kaposi's sarcoma-associated herpesvirus in oncogenesis].

Fujimuro M.

Seikagaku. 2004 Feb;76(2):140-3. Review. Japanese. No abstract available.

PMID:
15049141

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