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Biomarkers for Predicting Efficacies of Anti-PD1 Antibodies.

Kambayashi Y, Fujimura T, Hidaka T, Aiba S.

Front Med (Lausanne). 2019 Jul 31;6:174. doi: 10.3389/fmed.2019.00174. eCollection 2019. Review.


Why Do Carbonate Anions Have Extremely High Stability in the Interlayer Space of Layered Double Hydroxides? Case Study of Layered Double Hydroxide Consisting of Mg and Al (Mg/Al = 2).

Sasai R, Sato H, Sugata M, Fujimura T, Ishihara S, Deguchi K, Ohki S, Tansho M, Shimizu T, Oita N, Numoto M, Fujii Y, Kawaguchi S, Matsuoka Y, Hagura K, Abe T, Moriyoshi C.

Inorg Chem. 2019 Aug 8. doi: 10.1021/acs.inorgchem.9b01365. [Epub ahead of print]


Nonsense-mediated mRNA Decay Deficiency Affects the Auxin Response and Shoot Regeneration in Arabidopsis.

Chiam NC, Fujimura T, Sano R, Akiyoshi N, Hiroyama R, Watanabe Y, Motose H, Demura T, Ohtani M.

Plant Cell Physiol. 2019 Aug 6. pii: pcz154. doi: 10.1093/pcp/pcz154. [Epub ahead of print]


Current status and future perspective of robot-assisted radical cystectomy for invasive bladder cancer.

Fujimura T.

Int J Urol. 2019 Jul 30. doi: 10.1111/iju.14076. [Epub ahead of print] Review.


Carbon 11-choline positron emission tomography/computed tomography and palliative local therapy for castration-resistant prostate cancer.

Nozaki K, Kawai T, Fujimura T, Matsui H, Teshima T, Oshina T, Takahashi A, Sato Y, Yamada D, Azuma T, Hotta M, Nakajima K, Nakayama H, Minamimoto R, Kume H.

Int Urol Nephrol. 2019 Jul 19. doi: 10.1007/s11255-019-02233-y. [Epub ahead of print]


Successful Treatment of Unresectable Advanced Melanoma by Administration of Nivolumab With Ipilimumab Before Primary Tumor Resection.

Fujimura T, Kambayashi Y, Sato Y, Tanita K, Amagai R, Hashimoto A, Hidaka T, Aiba S.

Front Med (Lausanne). 2019 Jun 26;6:140. doi: 10.3389/fmed.2019.00140. eCollection 2019.


Perifolliculitis capitis abscedens et suffodiens treatment with tumor necrosis factor inhibitors: A case report and review of published cases.

Takahashi T, Yamasaki K, Terui H, Omori R, Tsuchiyama K, Fujimura T, Aiba S.

J Dermatol. 2019 Jul 4. doi: 10.1111/1346-8138.14998. [Epub ahead of print]


A novel technique to diagnose non-melanoma skin cancer by thermal conductivity measurements: Correlations with cancer stromal factors.

Fujimura T, Okabe T, Tanita K, Sato Y, Lyu C, Kambayashi Y, Maruyama S, Aiba S.

Exp Dermatol. 2019 Jul 2. doi: 10.1111/exd.13997. [Epub ahead of print]


Effect of Oral Branched-Chain Amino Acids and Glutamine Supplementation on Skeletal Muscle Atrophy After Total Gastrectomy in Rat Model.

Haba Y, Fujimura T, Oyama K, Kinoshita J, Miyashita T, Fushida S, Harada S, Ohta T.

J Surg Res. 2019 Jun 26;243:281-288. doi: 10.1016/j.jss.2019.05.041. [Epub ahead of print]


Roles of the hexosamine biosynthetic pathway and pentose phosphate pathway in bile acid-induced cancer development.

Munemoto M, Mukaisho KI, Miyashita T, Oyama K, Haba Y, Okamoto K, Kinoshita J, Ninomiya I, Fushida S, Taniura N, Sugihara H, Fujimura T.

Cancer Sci. 2019 Aug;110(8):2408-2420. doi: 10.1111/cas.14105. Epub 2019 Jul 23.


Robot-assisted radical prostatectomy versus volumetric modulated arc therapy: Comparison of front-line therapies for localized prostate cancer.

Taguchi S, Shiraishi K, Fujimura T, Naito A, Kawai T, Nakagawa K, Abe O, Kume H, Fukuhara H.

Radiother Oncol. 2019 Jun 5;140:62-67. doi: 10.1016/j.radonc.2019.05.015. [Epub ahead of print]


Addition of a β1-Blocker to Milrinone Treatment Improves Cardiac Function in Patients with Acute Heart Failure and Rapid Atrial Fibrillation.

Kobayashi S, Myoren T, Kajii T, Kohno M, Nanno T, Ishiguchi H, Nishimura S, Fukuda M, Hino A, Fujimura T, Ono M, Uchinoumi H, Tateishi H, Mochizuki M, Oda T, Okuda S, Yoshiga Y, Kawano R, Yano M.

Cardiology. 2019;142(4):195-202. doi: 10.1159/000499400. Epub 2019 May 28.


Living Donor Liver Re-Transplantation for Recurrent Hepatoblastoma in the Liver Graft following Complete Eradication of Peritoneal Metastases under Indocyanine Green Fluorescence Imaging.

Takahashi N, Yamada Y, Hoshino K, Kawaida M, Mori T, Abe K, Fujimura T, Matsubara K, Hibi T, Shinoda M, Obara H, Isshiki K, Shima H, Shimada H, Kameyama K, Fuchimoto Y, Kitagawa Y, Kuroda T.

Cancers (Basel). 2019 May 26;11(5). pii: E730. doi: 10.3390/cancers11050730.


Association of Baseline Serum Levels of CXCL5 With the Efficacy of Nivolumab in Advanced Melanoma.

Fujimura T, Sato Y, Tanita K, Lyu C, Kambayashi Y, Amagai R, Otsuka A, Fujisawa Y, Yoshino K, Matsushita S, Uchi H, Yamamoto Y, Hata H, Funakoshi T, Nonomura Y, Tanaka R, Okuhira H, Wada N, Hashimoto A, Aiba S.

Front Med (Lausanne). 2019 Apr 26;6:86. doi: 10.3389/fmed.2019.00086. eCollection 2019.


Lichen planus pemphigoides developing from patient with non-small-cell lung cancer treated with nivolumab.

Sato Y, Fujimura T, Mizuashi M, Aiba S.

J Dermatol. 2019 May 7. doi: 10.1111/1346-8138.14906. [Epub ahead of print] No abstract available.


Colon perforation due to antigenemia-negative cytomegalovirus gastroenteritis after liver transplantation: A case report and review of literature.

Yokose T, Obara H, Shinoda M, Nakano Y, Kitago M, Yagi H, Abe Y, Yamada Y, Matsubara K, Oshima G, Hori S, Ibuki S, Higashi H, Masuda Y, Hayashi M, Mori T, Kawaida M, Fujimura T, Hoshino K, Kameyama K, Kuroda T, Kitagawa Y.

World J Gastroenterol. 2019 Apr 21;25(15):1899-1906. doi: 10.3748/wjg.v25.i15.1899.


Successful treatment of multiple eruptive adult xanthogranuloma concomitant with xanthelasma palpebrarum with probucol.

Ishihara-Yusa S, Fujimura T, Lyu C, Sugawara M, Sakamoto K, Aiba S.

J Dermatol. 2019 May 3. doi: 10.1111/1346-8138.14903. [Epub ahead of print] No abstract available.


Classification of 3097 patients from the Japanese melanoma study database using the American joint committee on cancer eighth edition cancer staging system.

Fujisawa Y, Yoshikawa S, Minagawa A, Takenouchi T, Yokota K, Uchi H, Noma N, Nakamura Y, Asai J, Kato J, Fujiwara S, Fukushima S, Uehara J, Hoashi T, Kaji T, Fujimura T, Namikawa K, Yoshioka M, Murata N, Ogata D, Matsuyama K, Hatta N, Shibayama Y, Fujiyama T, Ishikawa M, Yamada D, Kishi A, Nakamura Y, Shimiauchi T, Fujii K, Fujimoto M, Ihn H, Katoh N.

J Dermatol Sci. 2019 May;94(2):284-289. doi: 10.1016/j.jdermsci.2019.04.003. Epub 2019 Apr 17.


Malassezia-derived aryl hydrocarbon receptor ligands enhance the CCL20/Th17/soluble CD163 pathogenic axis in extra-mammary Paget's disease.

Sato Y, Fujimura T, Tanita K, Chunbing L, Matsushita S, Fujisawa Y, Otsuka A, Yamamoto Y, Hidaka T, Aiba S.

Exp Dermatol. 2019 Aug;28(8):933-939. doi: 10.1111/exd.13944. Epub 2019 Jun 6.


Longitudinal change of comprehensive lower urinary tract symptoms and various types of urinary incontinence during robot-assisted radical prostatectomy.

Fujimura T, Igawa Y, Aizawa N, Niimi A, Yamada Y, Sugihara T, Kamei J, Sato Y, Matsunaga A, Yoshida M, Shinoda Y, Fukuhara H, Nakagawa T, Homma Y, Kume H.

Neurourol Urodyn. 2019 Apr;38(4):1067-1075. doi: 10.1002/nau.23952. Epub 2019 Mar 14.


Which types of clay minerals fix cesium ions effectively? the "cavity-charge matching effect".

Yamamoto T, Takigawa T, Fujimura T, Shimada T, Ishida T, Inoue H, Takagi S.

Phys Chem Chem Phys. 2019 May 8;21(18):9352-9356. doi: 10.1039/c9cp00457b.


Clinical and histopathological characteristics and survival analysis of 4594 Japanese patients with melanoma.

Fujisawa Y, Yoshikawa S, Minagawa A, Takenouchi T, Yokota K, Uchi H, Noma N, Nakamura Y, Asai J, Kato J, Fujiwara S, Fukushima S, Uehara J, Hoashi T, Kaji T, Fujimura T, Namikawa K, Yoshioka M, Murao N, Ogata D, Matsuyama K, Hatta N, Shibayama Y, Fujiyama T, Ishikawa M, Yamada D, Kishi A, Nakamura Y, Shimiauchi T, Fujii K, Fujimoto M, Ihn H, Katoh N.

Cancer Med. 2019 May;8(5):2146-2156. doi: 10.1002/cam4.2110. Epub 2019 Apr 1.


Three cases of nivolumab therapy-failed advanced melanoma successfully controlled by ipilimumab with intensity-modulated radiotherapy.

Amagai R, Fujimura T, Kambayashi Y, Sato Y, Tanita K, Hashimoto A, Aiba S.

J Dermatol. 2019 May;46(5):449-452. doi: 10.1111/1346-8138.14861. Epub 2019 Mar 25.


Efficacy of the proximal optimization technique on crossover stenting in coronary bifurcation lesions in the 3D-OCT bifurcation registry.

Murasato Y, Mori T, Okamura T, Nagoshi R, Fujimura T, Yamawaki M, Ono S, Serikawa T, Nakao F, Shite J; 3D-OCT Bifurcation Registry Investigators.

Int J Cardiovasc Imaging. 2019 Jun;35(6):981-990. doi: 10.1007/s10554-019-01581-1. Epub 2019 Mar 18.


Effects of Dietary Supplementation With Enterococcus faecium and Clostridium butyricum, Either Alone or in Combination, on Growth and Fecal Microbiota Composition of Post-weaning Pigs at a Commercial Farm.

Sato Y, Kuroki Y, Oka K, Takahashi M, Rao S, Sukegawa S, Fujimura T.

Front Vet Sci. 2019 Feb 28;6:26. doi: 10.3389/fvets.2019.00026. eCollection 2019.


Molecular Taxonomy of Interstitial Cystitis/Bladder Pain Syndrome Based on Whole Transcriptome Profiling by Next-Generation RNA Sequencing of Bladder Mucosal Biopsies.

Akiyama Y, Maeda D, Katoh H, Morikawa T, Niimi A, Nomiya A, Sato Y, Kawai T, Goto A, Fujimura T, Fukuhara H, Nakagawa T, Igawa Y, Ishikawa S, Fukayama M, Kume H, Homma Y.

J Urol. 2019 Aug;202(2):290-300. doi: 10.1097/JU.0000000000000234. Epub 2019 Jul 8.


First-in-human clinical study of novel technique to diagnose malignant melanoma via thermal conductivity measurements.

Okabe T, Fujimura T, Okajima J, Kambayashi Y, Aiba S, Maruyama S.

Sci Rep. 2019 Mar 7;9(1):3853. doi: 10.1038/s41598-019-40444-6.


The unique tropism of Mycobacterium leprae to the nasal epithelial cells can be explained by the mammalian cell entry protein 1A.

Fadlitha VB, Yamamoto F, Idris I, Dahlan H, Sato N, Aftitah VB, Febriyanda A, Fujimura T, Takimoto H.

PLoS Negl Trop Dis. 2019 Mar 5;13(3):e0006704. doi: 10.1371/journal.pntd.0006704. eCollection 2019 Mar.


Anticancer effect of nor-wogonin (5, 7, 8-trihydroxyflavone) on human triple-negative breast cancer cells via downregulation of TAK1, NF-κB, and STAT3.

Abd El-Hafeez AA, Khalifa HO, Mahdy EAM, Sharma V, Hosoi T, Ghosh P, Ozawa K, Montano MM, Fujimura T, Ibrahim ARN, Abdelhamid MAA, Pack SP, Shouman SA, Kawamoto S.

Pharmacol Rep. 2019 Apr;71(2):289-298. doi: 10.1016/j.pharep.2019.01.001. Epub 2019 Jan 7.


[A Case of Type 4 Ascending Colon Cancer Showing Early Postoperative Lymphangitis Carcinomatosa].

Katano K, Kurata T, Hagino S, Shoji Y, Sasaki S, Terada I, Yoshikawa A, Kitagawa H, Fujimura T.

Gan To Kagaku Ryoho. 2019 Jan;46(1):139-141. Japanese.


The effectiveness of transoral marsupialization for lingual thyroglossal duct cysts - Twelve successfully treated cases at a single institution.

Harumatsu T, Uchida G, Fujimura T, Kato M, Tomita H, Ishioka S, Shimotakahara A, Shimojima N, Ieiri S, Hirobe S.

J Pediatr Surg. 2019 Apr;54(4):766-770. doi: 10.1016/j.jpedsurg.2018.12.009. Epub 2019 Jan 23.


Correction: Effectiveness of plasma lyso-Gb3 as a biomarker for selecting high-risk patients with Fabry disease from multispecialty clinics for genetic analysis.

Maruyama H, Miyata K, Mikame M, Taguchi A, Guili C, Shimura M, Murayama K, Inoue T, Yamamoto S, Sugimura K, Tamita K, Kawasaki T, Kajihara J, Onishi A, Sugiyama H, Sakai T, Murata I, Oda T, Toyoda S, Hanawa K, Fujimura T, Ura S, Matsumura M, Takano H, Yamashita S, Matsukura G, Tazawa R, Shiga T, Ebato M, Satoh H, Ishii S.

Genet Med. 2019 May;21(5):1263. doi: 10.1038/s41436-019-0447-8.


Efficacy and safety of sirolimus treatment for intractable lymphatic anomalies: A study protocol for an open-label, single-arm, multicenter, prospective study (SILA).

Ozeki M, Asada R, Saito AM, Hashimoto H, Fujimura T, Kuroda T, Ueno S, Watanabe S, Nosaka S, Miyasaka M, Umezawa A, Matsuoka K, Maekawa T, Yamada Y, Fujino A, Hirakawa S, Furukawa T, Tajiri T, Kinoshita Y, Souzaki R, Fukao T.

Regen Ther. 2019 Jan 14;10:84-91. doi: 10.1016/j.reth.2018.12.001. eCollection 2019 Jun.


[A Case of Type 4 Gastric Cancer with Esophageal Invasion That Responded to Neoadjuvant Chemotherapy Containing S-1 and Oxaliplatin followed by Surgery].

Hagino S, Fujimura T, Kurata T, Shoji Y, Sasaki S, Terada I, Yoshikawa A, Kitagawa H, Izumi R, Saito K.

Gan To Kagaku Ryoho. 2018 Dec;45(13):2327-2329. Japanese.


CD30-Positive Angioinvasive Lymphomatoid Papulosis (Type E) Developing from Parapsoriasis en Plaque.

Fujimura T, Lyu C, Tsuchiyama K, Aiba S.

Case Rep Oncol. 2018 Dec 13;11(3):850-854. doi: 10.1159/000495689. eCollection 2018 Sep-Dec.


Accumulation of exhausted CD8+ T cells in extramammary Paget's disease.

Iga N, Otsuka A, Yamamoto Y, Nakashima C, Honda T, Kitoh A, Nakajima S, Egawa G, Nomura T, Dainichi T, Matsushita S, Tanizaki H, Yamamoto Y, Funakoshi T, Fujisawa Y, Fujimura T, Hata H, Ishida Y, Kabashima K.

PLoS One. 2019 Jan 25;14(1):e0211135. doi: 10.1371/journal.pone.0211135. eCollection 2019.


Successful treatment of unresectable recurrent programmed death ligand 1 moderately-expressing malignant melanoma of the nasal cavity with pembrolizumab monotherapy.

Fujimura T, Kambayashi Y, Sato Y, Tanita K, Tono H, Lyu C, Takahashi T, Hashimoto A, Aiba S.

J Dermatol. 2019 Jul;46(7):e260. doi: 10.1111/1346-8138.14786. Epub 2019 Jan 23. No abstract available.


Successful treatment of microcystic adnexal carcinoma on the philtrum with oral S-1 monotherapy.

Haga T, Fujimura T, Aiba S.

J Dermatol. 2019 Jun;46(6):e208-e209. doi: 10.1111/1346-8138.14770. Epub 2019 Jan 21. No abstract available.


Pembrolizumab resolves adult ashy dermatosis developing in patients with squamous cell carcinoma of the lung.

Takeda K, Fujimura T, Tsuchiyama K, Lyu C, Aiba S.

J Dermatol. 2019 Mar;46(3):271-273. doi: 10.1111/1346-8138.14775. Epub 2019 Jan 21.


Molecular targeting of HER2-overexpressing biliary tract cancer cells with trastuzumab emtansine, an antibody-cytotoxic drug conjugate.

Yamashita-Kashima Y, Yoshimura Y, Fujimura T, Shu S, Yanagisawa M, Yorozu K, Furugaki K, Higuchi R, Shoda J, Harada N.

Cancer Chemother Pharmacol. 2019 Apr;83(4):659-671. doi: 10.1007/s00280-019-03768-8. Epub 2019 Jan 18.


Severe rhabdomyolysis developing in an advanced melanoma patient treated by pembrolizumab followed by dabrafenib trametinib combined therapy.

Irimada M, Fujimura T, Kambayashi Y, Tsukada A, Takahashi T, Hashimoto A, Aiba S.

J Dermatol. 2019 Jul;46(7):e256-e258. doi: 10.1111/1346-8138.14778. Epub 2019 Jan 18. No abstract available.


Laparoscopic Partial Closure for Congenital Portosystemic Shunt-Indications, Postoperative Management, and Subsequent Complete Closure.

Mori T, Yamada Y, Abe K, Takahashi N, Kano M, Fujimura T, Watanabe T, Nakatsuka S, Hoshino K, Kuroda T.

J Laparoendosc Adv Surg Tech A. 2019 Apr;29(4):573-578. doi: 10.1089/lap.2018.0581. Epub 2019 Jan 7.


BRAF kinase inhibitors for treatment of melanoma: developments from early-stage animal studies to Phase II clinical trials.

Fujimura T, Hidaka T, Kambayashi Y, Aiba S.

Expert Opin Investig Drugs. 2019 Feb;28(2):143-148. doi: 10.1080/13543784.2019.1558442. Epub 2018 Dec 16. Review.


Synthesis, photodynamic activities, and cytotoxicity of new water-soluble cationic gallium(III) and zinc(II) phthalocyanines.

Fujishiro R, Sonoyama H, Ide Y, Fujimura T, Sasai R, Nagai A, Mori S, Kaufman NEM, Zhou Z, Vicente MGH, Ikeue T.

J Inorg Biochem. 2019 Mar;192:7-16. doi: 10.1016/j.jinorgbio.2018.11.013. Epub 2018 Dec 5.


Intake of a fermented plant product attenuates allergic symptoms without changing systemic immune responses in a mouse model of Japanese cedar pollinosis.

Fujimura T, Hori A, Torii H, Kishida S, Matsuura Y, Kawamoto S.

World Allergy Organ J. 2018 Dec 4;11(1):31. doi: 10.1186/s40413-018-0213-4. eCollection 2018.


Serum Level of Soluble CD163 May Be a Predictive Marker of the Effectiveness of Nivolumab in Patients With Advanced Cutaneous Melanoma.

Fujimura T, Sato Y, Tanita K, Kambayashi Y, Otsuka A, Fujisawa Y, Yoshino K, Matsushita S, Funakoshi T, Hata H, Yamamoto Y, Uchi H, Nonomura Y, Tanaka R, Aoki M, Imafuku K, Okuhira H, Wada N, Irie H, Hidaka T, Hashimoto A, Aiba S.

Front Oncol. 2018 Nov 19;8:530. doi: 10.3389/fonc.2018.00530. eCollection 2018.


Keratoacanthoma Centrifugum Marginatum with Spontaneous Regression and Its Possible Differential Diagnosis.

Amagai R, Fujimura T, Kambayashi Y, Furudate S, Sato Y, Tanita K, Hashimoto A, Aiba S.

Case Rep Oncol. 2018 Oct 24;11(3):671-675. doi: 10.1159/000493089. eCollection 2018 Sep-Dec.


Breast Cancer Metastasis in the Skin with Hyperkeratotic Pigmentation Caused by Melanocyte Colonization.

Ishihara-Yusa S, Fujimura T, Lyu C, Sugawara M, Sakamoto K, Aiba S.

Case Rep Oncol. 2018 Oct 23;11(3):660-664. doi: 10.1159/000493186. eCollection 2018 Sep-Dec.


The cap-snatching reaction of yeast L-A double-stranded RNA virus is reversible and the catalytic sites on both Gag and the Gag domain of Gag-Pol are active.

Fujimura T, Esteban R.

Mol Microbiol. 2019 Feb;111(2):395-404. doi: 10.1111/mmi.14161. Epub 2018 Dec 4.


Impact of water exposure on skin barrier permeability and ultrastructure.

Ogawa-Fuse C, Morisaki N, Shima K, Hotta M, Sugata K, Ichihashi T, Oguri M, Yoshida O, Fujimura T.

Contact Dermatitis. 2019 Apr;80(4):228-233. doi: 10.1111/cod.13174. Epub 2018 Dec 14.


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