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Items: 11


Aire Inhibits the Generation of a Perinatal Population of Interleukin-17A-Producing γδ T Cells to Promote Immunologic Tolerance.

Fujikado N, Mann AO, Bansal K, Romito KR, Ferre EMN, Rosenzweig SD, Lionakis MS, Benoist C, Mathis D.

Immunity. 2016 Nov 15;45(5):999-1012. doi: 10.1016/j.immuni.2016.10.023.


Exacerbation of experimental autoimmune encephalomyelitis in mice deficient for DCIR, an inhibitory C-type lectin receptor.

Seno A, Maruhashi T, Kaifu T, Yabe R, Fujikado N, Ma G, Ikarashi T, Kakuta S, Iwakura Y.

Exp Anim. 2015;64(2):109-19.


DCIR maintains bone homeostasis by regulating IFN-γ production in T cells.

Maruhashi T, Kaifu T, Yabe R, Seno A, Chung SH, Fujikado N, Iwakura Y.

J Immunol. 2015 Jun 15;194(12):5681-91. doi: 10.4049/jimmunol.1500273. Epub 2015 Apr 29.


Immune tolerance. Regulatory T cells generated early in life play a distinct role in maintaining self-tolerance.

Yang S, Fujikado N, Kolodin D, Benoist C, Mathis D.

Science. 2015 May 1;348(6234):589-94. doi: 10.1126/science.aaa7017. Epub 2015 Mar 19.


CXC chemokine receptor 4 expressed in T cells plays an important role in the development of collagen-induced arthritis.

Chung SH, Seki K, Choi BI, Kimura KB, Ito A, Fujikado N, Saijo S, Iwakura Y.

Arthritis Res Ther. 2010;12(5):R188. doi: 10.1186/ar3158. Epub 2010 Oct 12.


IL-1 plays an important role in the bone metabolism under physiological conditions.

Lee YM, Fujikado N, Manaka H, Yasuda H, Iwakura Y.

Int Immunol. 2010 Oct;22(10):805-16. doi: 10.1093/intimm/dxq431. Epub 2010 Aug 2.


Dectin-2 recognition of alpha-mannans and induction of Th17 cell differentiation is essential for host defense against Candida albicans.

Saijo S, Ikeda S, Yamabe K, Kakuta S, Ishigame H, Akitsu A, Fujikado N, Kusaka T, Kubo S, Chung SH, Komatsu R, Miura N, Adachi Y, Ohno N, Shibuya K, Yamamoto N, Kawakami K, Yamasaki S, Saito T, Akira S, Iwakura Y.

Immunity. 2010 May 28;32(5):681-91. doi: 10.1016/j.immuni.2010.05.001. Epub 2010 May 20.


Differential roles of interleukin-17A and -17F in host defense against mucoepithelial bacterial infection and allergic responses.

Ishigame H, Kakuta S, Nagai T, Kadoki M, Nambu A, Komiyama Y, Fujikado N, Tanahashi Y, Akitsu A, Kotaki H, Sudo K, Nakae S, Sasakawa C, Iwakura Y.

Immunity. 2009 Jan 16;30(1):108-19. doi: 10.1016/j.immuni.2008.11.009.


Dcir deficiency causes development of autoimmune diseases in mice due to excess expansion of dendritic cells.

Fujikado N, Saijo S, Yonezawa T, Shimamori K, Ishii A, Sugai S, Kotaki H, Sudo K, Nose M, Iwakura Y.

Nat Med. 2008 Feb;14(2):176-80. doi: 10.1038/nm1697. Epub 2008 Jan 20.


Dectin-1 is required for host defense against Pneumocystis carinii but not against Candida albicans.

Saijo S, Fujikado N, Furuta T, Chung SH, Kotaki H, Seki K, Sudo K, Akira S, Adachi Y, Ohno N, Kinjo T, Nakamura K, Kawakami K, Iwakura Y.

Nat Immunol. 2007 Jan;8(1):39-46. Epub 2006 Dec 10.


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