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Theracurmin inhibits intestinal polyp development in Apc-mutant mice by inhibiting inflammation-related factors.

Adachi S, Hamoya T, Fujii G, Narita T, Komiya M, Miyamoto S, Kurokawa Y, Takahashi M, Takayama T, Ishikawa H, Tashiro K, Mutoh M.

Cancer Sci. 2020 Jan 28. doi: 10.1111/cas.14329. [Epub ahead of print]


The Radical Scavenger NZ-419 Suppresses Intestinal Polyp Development in Apc-Mutant Mice.

Kurokawa Y, Fujii G, Tomono S, Miyamoto S, Hamoya T, Takahashi M, Narita T, Komiya M, Kobayashi M, Higami Y, Mutoh M.

J Clin Med. 2020 Jan 18;9(1). pii: E270. doi: 10.3390/jcm9010270.


Activation of NF-E2 p45-related factor-2 transcription and inhibition of intestinal tumor development by AHCC, a standardized extract of cultured Lentinula edodes mycelia.

Takahashi M, Fujii G, Hamoya T, Kurokawa Y, Matsuzawa Y, Miki K, Komiya M, Narita T, Mutoh M.

J Clin Biochem Nutr. 2019 Nov;65(3):203-208. doi: 10.3164/jcbn.19-36. Epub 2019 Sep 27.


The rBC2LCN-positive subpopulation of PC-3 cells exhibits cancer stem-like properties.

Mawaribuchi S, Onuma Y, Aiki Y, Kuriyama Y, Mutoh M, Fujii G, Ito Y.

Biochem Biophys Res Commun. 2019 Jul 12;515(1):176-182. doi: 10.1016/j.bbrc.2019.05.108. Epub 2019 May 24.


Novel screening system revealed that intracellular cholesterol trafficking can be a good target for colon cancer prevention.

Miyamoto S, Narita T, Komiya M, Fujii G, Hamoya T, Nakanishi R, Tamura S, Kurokawa Y, Takahashi M, Mutoh M.

Sci Rep. 2019 Apr 17;9(1):6192. doi: 10.1038/s41598-019-42363-y.


DC carpet cloak designed by topology optimization based on covariance matrix adaptation evolution strategy.

Fujii G, Akimoto Y.

Opt Lett. 2019 Apr 15;44(8):2057-2060. doi: 10.1364/OL.44.002057.


Inhibition of NF-kappaB transcriptional activity enhances fucoxanthinol-induced apoptosis in colorectal cancer cells.

Tamura S, Narita T, Fujii G, Miyamoto S, Hamoya T, Kurokawa Y, Takahashi M, Miki K, Matsuzawa Y, Komiya M, Terasaki M, Yano T, Mutoh M.

Genes Environ. 2019 Jan 22;41:1. doi: 10.1186/s41021-018-0116-1. eCollection 2019.


Long-term results of a modified Spitzy shelf operation for developmental dysplasia of the hip in adults and adolescents.

Tanaka H, Chiba D, Mori Y, Kuwahara Y, Baba K, Yamada N, Fujii G, Itoi E.

Eur J Orthop Surg Traumatol. 2018 Oct;28(7):1341-1347. doi: 10.1007/s00590-018-2191-1. Epub 2018 Mar 29.


Enhancing Efficacy and Stability of an Antiheroin Vaccine: Examination of Antinociception, Opioid Binding Profile, and Lethality.

Hwang CS, Bremer PT, Wenthur CJ, Ho SO, Chiang S, Ellis B, Zhou B, Fujii G, Janda KD.

Mol Pharm. 2018 Mar 5;15(3):1062-1072. doi: 10.1021/acs.molpharmaceut.7b00933. Epub 2018 Feb 19.


Monomeric M2e antigen in VesiVax® liposomes stimulates protection against type a strains of influenza comparable to liposomes with multimeric forms of M2e.

Adler-Moore JP, Ernst W, Kim H, Ward N, Chiang SM, Do T, Fujii G.

J Liposome Res. 2017 Sep;27(3):210-220. doi: 10.1080/08982104.2017.1381708. Epub 2017 Oct 5.


Anticarcinogenic Effects of Dried Citrus Peel in Colon Carcinogenesis Due to Inhibition of Oxidative Stress.

Onuma W, Asai D, Tomono S, Miyamoto S, Fujii G, Hamoya T, Nagano A, Takahashi S, Masumori S, Miyoshi N, Wakabayashi K, Mutoh M.

Nutr Cancer. 2017 Aug-Sep;69(6):855-861. doi: 10.1080/01635581.2017.1339096. Epub 2017 Jul 18.


Chemopreventive effects of a low-side-effect antibiotic drug, erythromycin, on mouse intestinal tumors.

Hamoya T, Miyamoto S, Tomono S, Fujii G, Nakanishi R, Komiya M, Tamura S, Fujimoto K, Toshima J, Wakabayashi K, Mutoh M.

J Clin Biochem Nutr. 2017 May;60(3):199-207. doi: 10.3164/jcbn.16-107. Epub 2017 Apr 14.


Investigation of third-order dispersion of long-range surface-plasmon-polariton waveguides using a Hong-Ou-Mandel interferometer.

Sakaidani T, Kobayashi R, Namekata N, Fujii G, Fukuda D, Inoue S.

Opt Express. 2017 Apr 17;25(8):9490-9501. doi: 10.1364/OE.25.009490.


Impact of Acetazolamide, a Carbonic Anhydrase Inhibitor, on the Development of Intestinal Polyps in Min Mice.

Noma N, Fujii G, Miyamoto S, Komiya M, Nakanishi R, Shimura M, Tanuma SI, Mutoh M.

Int J Mol Sci. 2017 Apr 17;18(4). pii: E851. doi: 10.3390/ijms18040851.


Preventive Effects of Heat-Killed Enterococcus faecalis Strain EC-12 on Mouse Intestinal Tumor Development.

Miyamoto S, Komiya M, Fujii G, Hamoya T, Nakanishi R, Fujimoto K, Tamura S, Kurokawa Y, Takahashi M, Ijichi T, Mutoh M.

Int J Mol Sci. 2017 Apr 13;18(4). pii: E826. doi: 10.3390/ijms18040826.


Toll-like receptor 3 adjuvant in combination with virus-like particles elicit a humoral response against HIV.

Poteet E, Lewis P, Chen C, Ho SO, Do T, Chiang S, Labranche C, Montefiori D, Fujii G, Yao Q.

Vaccine. 2016 Nov 21;34(48):5886-5894. doi: 10.1016/j.vaccine.2016.10.036. Epub 2016 Oct 27.


Factors associated with functional limitations in the daily living activities of Japanese hip osteoarthritis patients.

Kondo K, Jingushi S, Ohfuji S, Sofue M, Itoman M, Matsumoto T, Hamada Y, Shindo H, Takatori Y, Yamada H, Yasunaga Y, Ito H, Mori S, Owan I, Fujii G, Ohashi H, Fukushima W, Maeda A, Inui M, Takahashi S, Hirota Y.

Int J Rheum Dis. 2017 Oct;20(10):1372-1382. doi: 10.1111/1756-185X.12955. Epub 2016 Dec 10.


Topology-optimized carpet cloaks based on a level-set boundary expression.

Fujii G, Ueta T.

Phys Rev E. 2016 Oct;94(4-1):043301. Epub 2016 Oct 3.


Stability of an amphipathic helix-hairpin surfactant peptide in liposomes.

Waring AJ, Gupta M, Gordon LM, Fujii G, Walther FJ.

Biochim Biophys Acta. 2016 Dec;1858(12):3113-3119. doi: 10.1016/j.bbamem.2016.09.014. Epub 2016 Sep 21.


Factors associated with diagnostic stage of hip osteoarthritis due to acetabular dysplasia among Japanese female patients: a cross-sectional study.

Ohfuji S, Jingushi S, Kondo K, Sofue M, Itoman M, Matsumoto T, Hamada Y, Shindo H, Takatori Y, Yamada H, Yasunaga Y, Ito H, Mori S, Owan I, Fujii G, Ohashi H, Takahashi S, Hirota Y.

BMC Musculoskelet Disord. 2016 Aug 2;17:320. doi: 10.1186/s12891-016-1179-4.


Assessment of free fatty acids and cholesteryl esters delivered in liposomes as novel class of antibiotic.

Cheung Lam AH, Sandoval N, Wadhwa R, Gilkes J, Do TQ, Ernst W, Chiang SM, Kosina S, Howard Xu H, Fujii G, Porter E.

BMC Res Notes. 2016 Jul 8;9:337. doi: 10.1186/s13104-016-2138-8.


Where the colorectal cancer chemoprevention is and where it is going.

Mutoh M, Fujii G, Miyamoto S.

Nihon Shokakibyo Gakkai Zasshi. 2016 Jul;113(7):1186-90. doi: 10.11405/nisshoshi.113.1186. Japanese. No abstract available.


Effects of NSAIDs on the risk factors of colorectal cancer: a mini review.

Hamoya T, Fujii G, Miyamoto S, Takahashi M, Totsuka Y, Wakabayashi K, Toshima J, Mutoh M.

Genes Environ. 2016 Apr 1;38:6. doi: 10.1186/s41021-016-0033-0. eCollection 2016. Review.


Irsogladine maleate, a gastric mucosal protectant, suppresses intestinal polyp development in Apc-mutant mice.

Onuma W, Tomono S, Miyamoto S, Fujii G, Hamoya T, Fujimoto K, Miyoshi N, Fukai F, Wakabayashi K, Mutoh M.

Oncotarget. 2016 Feb 23;7(8):8640-52. doi: 10.18632/oncotarget.7082.


Endoscopic management of familial adenomatous polyposis in patients refusing colectomy.

Ishikawa H, Mutoh M, Iwama T, Suzuki S, Abe T, Takeuchi Y, Nakamura T, Ezoe Y, Fujii G, Wakabayashi K, Nakajima T, Sakai T.

Endoscopy. 2016 Jan;48(1):51-5. doi: 10.1055/s-0034-1392774. Epub 2015 Sep 9.


A Novel Prime and Boost Regimen of HIV Virus-Like Particles with TLR4 Adjuvant MPLA Induces Th1 Oriented Immune Responses against HIV.

Poteet E, Lewis P, Li F, Zhang S, Gu J, Chen C, Ho SO, Do T, Chiang S, Fujii G, Yao Q.

PLoS One. 2015 Aug 27;10(8):e0136862. doi: 10.1371/journal.pone.0136862. eCollection 2015.


Suppressive effects of the NADPH oxidase inhibitor apocynin on intestinal tumorigenesis in obese KK-A(y) and Apc mutant Min mice.

Komiya M, Fujii G, Miyamoto S, Takahashi M, Ishigamori R, Onuma W, Ishino K, Totsuka Y, Fujimoto K, Mutoh M.

Cancer Sci. 2015 Nov;106(11):1499-505. doi: 10.1111/cas.12801. Epub 2015 Oct 16.


Suppression of intestinal carcinogenesis in Apc-mutant mice by limonin.

Shimizu S, Miyamoto S, Fujii G, Nakanishi R, Onuma W, Ozaki Y, Fujimoto K, Yano T, Mutoh M.

J Clin Biochem Nutr. 2015 Jul;57(1):39-43. doi: 10.3164/jcbn.15-28. Epub 2015 Jun 17.


Involvement of trefoil factor family 2 in the enlargement of intestinal tumors in Apc(Min/+) mice.

Fujimoto K, Fujii G, Taguchi K, Yasuda K, Matsuo Y, Hashiyama A, Mutoh M, Tanaka H, Wada M.

Biochem Biophys Res Commun. 2015 Aug 7;463(4):859-63. doi: 10.1016/j.bbrc.2015.06.025. Epub 2015 Jun 6.


Topology-optimized multiple-disk resonators obtained using level set expression incorporating surface effects.

Fujii G, Ueta T, Mizuno M, Nakamura M.

Opt Express. 2015 May 4;23(9):11312-26. doi: 10.1364/OE.23.011312.


The nuclear-encoded sigma factor SIG4 directly activates transcription of chloroplast psbA and ycf17 genes in the unicellular red alga Cyanidioschyzon merolae.

Fujii G, Imamura S, Era A, Miyagishima SY, Hanaoka M, Tanaka K.

FEMS Microbiol Lett. 2015 May;362(10). pii: fnv063. doi: 10.1093/femsle/fnv063. Epub 2015 Apr 15.


Involvement of NADPH oxidases in suppression of cyclooxygenase-2 promoter-dependent transcriptional activities by sesamol.

Shimizu S, Ishigamori R, Fujii G, Takahashi M, Onuma W, Terasaki M, Yano T, Mutoh M.

J Clin Biochem Nutr. 2015 Mar;56(2):118-22. doi: 10.3164/jcbn.14-89. Epub 2014 Dec 16.


Intestinal Peyer's patches prevent tumorigenesis in Apc (Min/+) mice.

Fujimoto K, Fujii G, Sakurai H, Yoshitome H, Mutoh M, Wada M.

J Clin Biochem Nutr. 2015 Jan;56(1):43-8. doi: 10.3164/jcbn.14-115. Epub 2014 Nov 28.


Sesamol suppresses cyclooxygenase-2 transcriptional activity in colon cancer cells and modifies intestinal polyp development in Apc (Min/+) mice.

Shimizu S, Fujii G, Takahashi M, Nakanishi R, Komiya M, Shimura M, Noma N, Onuma W, Terasaki M, Yano T, Mutoh M.

J Clin Biochem Nutr. 2014 Mar;54(2):95-101. doi: 10.3164/jcbn.13-91. Epub 2014 Feb 19.


Bi-directional regulation between adiponectin and plasminogen activator-inhibitor-1 in 3T3-L1 cells.

Komiya M, Fujii G, Takahashi M, Shimura M, Noma N, Shimizu S, Onuma W, Mutoh M.

In Vivo. 2014 Jan-Feb;28(1):13-9.


Heat shock factor 1 accelerates hepatocellular carcinoma development by activating nuclear factor-κB/mitogen-activated protein kinase.

Chuma M, Sakamoto N, Nakai A, Hige S, Nakanishi M, Natsuizaka M, Suda G, Sho T, Hatanaka K, Matsuno Y, Yokoo H, Kamiyama T, Taketomi A, Fujii G, Tashiro K, Hikiba Y, Fujimoto M, Asaka M, Maeda S.

Carcinogenesis. 2014 Feb;35(2):272-81. doi: 10.1093/carcin/bgt343. Epub 2013 Oct 15.


Nuclear-encoded chloroplast RNA polymerase sigma factor SIG2 activates chloroplast-encoded phycobilisome genes in a red alga, Cyanidioschyzon merolae.

Fujii G, Imamura S, Hanaoka M, Tanaka K.

FEBS Lett. 2013 Oct 11;587(20):3354-9. doi: 10.1016/j.febslet.2013.08.031. Epub 2013 Sep 10.


[Ascending aorta replacement late after aortic valve replacement].

Hayashi Y, Ito T, Maekawa A, Sawaki S, Fujii G, Hoshino S, Tokoro M, Yanagisawa J.

Kyobu Geka. 2013 Jul;66(7):523-6; discussion 526-9. Japanese.


Prevention and intervention trials for colorectal cancer.

Komiya M, Fujii G, Takahashi M, Iigo M, Mutoh M.

Jpn J Clin Oncol. 2013 Jul;43(7):685-94. doi: 10.1093/jjco/hyt053. Epub 2013 Apr 23. Review.


True or apparent leg length discrepancy: which is a better predictor of short-term functional outcomes after total hip arthroplasty?

Nakanowatari T, Suzukamo Y, Suga T, Okii A, Fujii G, Izumi S.

J Geriatr Phys Ther. 2013 Oct-Dec;36(4):169-74. doi: 10.1519/JPT.0b013e318282d2f1.


Enhancing nicotine vaccine immunogenicity with liposomes.

Lockner JW, Ho SO, McCague KC, Chiang SM, Do TQ, Fujii G, Janda KD.

Bioorg Med Chem Lett. 2013 Feb 15;23(4):975-8. doi: 10.1016/j.bmcl.2012.12.048. Epub 2012 Dec 27.


Reconstruction of mitral valve chordae and leaflets with one piece of autologous pericardium in extensively destructed mitral valve due to active infective endocarditis.

Ito T, Maekawa A, Sawaki S, Fujii G, Hoshino S, Hayashi Y.

Gen Thorac Cardiovasc Surg. 2013 Oct;61(10):571-3. doi: 10.1007/s11748-012-0195-z. Epub 2013 Jan 5.


Suppressive effect of pioglitazone, a PPAR gamma ligand, on azoxymethane-induced colon aberrant crypt foci in KK-Ay mice.

Ueno T, Teraoka N, Takasu S, Nakano K, Takahashi M, Yamamoto M, Fujii G, Komiya M, Yanaka A, Wakabayashi K, Mutoh M.

Asian Pac J Cancer Prev. 2012;13(8):4067-73.


Novel compound SK-1009 suppresses interleukin-6 expression through modulation of activation of nuclear factor-kappaB pathway.

Shimura M, Yamamoto M, Fujii G, Takahashi M, Komiya M, Noma N, Tanuma S, Yanaka A, Mutoh M.

Biol Pharm Bull. 2012;35(12):2186-91. Epub 2012 Sep 27.


Involvement of inflammatory factors in pancreatic carcinogenesis and preventive effects of anti-inflammatory agents.

Takahashi M, Mutoh M, Ishigamori R, Fujii G, Imai T.

Semin Immunopathol. 2013 Mar;35(2):203-27. doi: 10.1007/s00281-012-0340-x. Epub 2012 Sep 7. Review.


Diagnostic and prognostic significance of the alternatively spliced ACTN4 variant in high-grade neuroendocrine pulmonary tumours.

Miyanaga A, Honda K, Tsuta K, Masuda M, Yamaguchi U, Fujii G, Miyamoto A, Shinagawa S, Miura N, Tsuda H, Sakuma T, Asamura H, Gemma A, Yamada T.

Ann Oncol. 2013 Jan;24(1):84-90. doi: 10.1093/annonc/mds215. Epub 2012 Aug 10.


Marked discrepancy in pressure gradient between Doppler and catheter examinations on Medtronic Mosaic valve in aortic position.

Ito T, Maekawa A, Fujii G, Sawaki S, Hoshino S, Hayashi Y.

Gen Thorac Cardiovasc Surg. 2012 Dec;60(12):818-21. doi: 10.1007/s11748-012-0089-0. Epub 2012 Jun 12.


Preservation of photon indistinguishability after transmission through surface-plasmon-polariton waveguide.

Fujii G, Segawa T, Mori S, Namekata N, Fukuda D, Inoue S.

Opt Lett. 2012 May 1;37(9):1535-7. doi: 10.1364/OL.37.001535.


Suppression of intestinal polyp development in Apc(Min/+) mice through inhibition of P-glycoprotein using verapamil.

Fujimoto K, Fujii G, Mutoh M, Yasunaga M, Tanaka H, Wada M.

Eur J Cancer Prev. 2013 Jan;22(1):8-10. doi: 10.1097/CEJ.0b013e328353ede8.


Study on transition from photonic-crystal laser to random laser.

Fujii G, Matsumoto T, Takahashi T, Ueta T.

Opt Express. 2012 Mar 26;20(7):7300-15. doi: 10.1364/OE.20.007300.


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