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Items: 1 to 50 of 99

1.

Lead Optimization Yields High Affinity Frizzled 7-Targeting Peptides That Modulate Clostridium difficile Toxin B Pathogenicity in Epithelial Cells.

Hansen S, Nile AH, Mehta SC, Fuhrmann J, Hannoush RN.

J Med Chem. 2019 Sep 12;62(17):7739-7750. doi: 10.1021/acs.jmedchem.9b00500. Epub 2019 Sep 3.

PMID:
31429553
2.

Accurate Detection of Helicobacter pylori Antigen in Human Stool Specimens by Two Novel Immunoassays.

Ignatius R, Berg C, Weiland C, Darmer A, Wenzel T, Lorenz M, Fuhrmann J, Müller M.

Eur J Microbiol Immunol (Bp). 2019 May 28;9(2):29-31. doi: 10.1556/1886.2019.00008. eCollection 2019 Jun 3.

3.

Detection of Enterobius vermicularis in greater Berlin, 2007-2017: seasonality and increased frequency of detection.

Friesen J, Bergmann C, Neuber R, Fuhrmann J, Wenzel T, Durst A, Müller M, Ignatius R.

Eur J Clin Microbiol Infect Dis. 2019 Apr;38(4):719-723. doi: 10.1007/s10096-019-03495-1. Epub 2019 Feb 2.

PMID:
30712227
4.

A structural mechanism for directing corepressor-selective inverse agonism of PPARγ.

Brust R, Shang J, Fuhrmann J, Mosure SA, Bass J, Cano A, Heidari Z, Chrisman IM, Nemetchek MD, Blayo AL, Griffin PR, Kamenecka TM, Hughes TS, Kojetin DJ.

Nat Commun. 2018 Nov 8;9(1):4687. doi: 10.1038/s41467-018-07133-w.

5.

Immature stages of three species of Inca LePeletier Serville, 1828 (Coleoptera: Scarabaeidae: Cetoniinae) and morphology of phytophagous scarab beetle pupa.

Sousa R, Fuhrmann J, KouklÍk O, ŠÍpek P.

Zootaxa. 2018 Jun 14;4434(1):65-88. doi: 10.11646/zootaxa.4434.1.4.

PMID:
30313200
6.

Multicenter Evaluation of Two Next-Generation HIV-1 Quantitation Assays, Aptima Quant Dx and Cobas 6800, in Comparison to the RealTime HIV-1 Reference Assay.

Wiesmann F, Ehret R, Naeth G, Däumer M, Fuhrmann J, Kaiser R, Noah C, Obermeier M, Schalasta G, Tiemann C, Wolf E, Knechten H, Braun P.

J Clin Microbiol. 2018 Sep 25;56(10). pii: e00292-18. doi: 10.1128/JCM.00292-18. Print 2018 Oct.

7.

Defining a conformational ensemble that directs activation of PPARγ.

Chrisman IM, Nemetchek MD, de Vera IMS, Shang J, Heidari Z, Long Y, Reyes-Caballero H, Galindo-Murillo R, Cheatham TE 3rd, Blayo AL, Shin Y, Fuhrmann J, Griffin PR, Kamenecka TM, Kojetin DJ, Hughes TS.

Nat Commun. 2018 May 4;9(1):1794. doi: 10.1038/s41467-018-04176-x.

8.

Evaluation of the Roche LightMix Gastro parasites multiplex PCR assay detecting Giardia duodenalis, Entamoeba histolytica, cryptosporidia, Dientamoeba fragilis, and Blastocystis hominis.

Friesen J, Fuhrmann J, Kietzmann H, Tannich E, Müller M, Ignatius R.

Clin Microbiol Infect. 2018 Dec;24(12):1333-1337. doi: 10.1016/j.cmi.2018.03.025. Epub 2018 Mar 23.

PMID:
29581055
9.

Viruses in Soil Ecosystems: An Unknown Quantity Within an Unexplored Territory.

Williamson KE, Fuhrmann JJ, Wommack KE, Radosevich M.

Annu Rev Virol. 2017 Sep 29;4(1):201-219. doi: 10.1146/annurev-virology-101416-041639. Review.

PMID:
28961409
10.

Branched-chain amino acid catabolism rather than amino acids plasma concentrations is associated with diet-induced changes in insulin resistance in overweight to obese individuals.

Haufe S, Engeli S, Kaminski J, Witt H, Rein D, Kamlage B, Utz W, Fuhrmann JC, Haas V, Mähler A, Schulz-Menger J, Luft FC, Boschmann M, Jordan J.

Nutr Metab Cardiovasc Dis. 2017 Oct;27(10):858-864. doi: 10.1016/j.numecd.2017.07.001. Epub 2017 Jul 11.

PMID:
28958691
11.

Metabolic profiles in heart failure due to non-ischemic cardiomyopathy at rest and under exercise.

Mueller-Hennessen M, Sigl J, Fuhrmann JC, Witt H, Reszka R, Schmitz O, Kastler J, Fischer JJ, Müller OJ, Giannitsis E, Weis T, Frey N, Katus HA.

ESC Heart Fail. 2017 May;4(2):178-189. doi: 10.1002/ehf2.12133. Epub 2017 Mar 8.

12.

Direct Comparison of 4 Very Early Rule-Out Strategies for Acute Myocardial Infarction Using High-Sensitivity Cardiac Troponin I.

Boeddinghaus J, Nestelberger T, Twerenbold R, Wildi K, Badertscher P, Cupa J, Bürge T, Mächler P, Corbière S, Grimm K, Giménez MR, Puelacher C, Shrestha S, Flores Widmer D, Fuhrmann J, Hillinger P, Sabti Z, Honegger U, Schaerli N, Kozhuharov N, Rentsch K, Miró Ò, López B, Martin-Sanchez FJ, Rodriguez-Adrada E, Morawiec B, Kawecki D, Ganovská E, Parenica J, Lohrmann J, Kloos W, Buser A, Geigy N, Keller DI, Osswald S, Reichlin T, Mueller C.

Circulation. 2017 Apr 25;135(17):1597-1611. doi: 10.1161/CIRCULATIONAHA.116.025661. Epub 2017 Mar 10.

PMID:
28283497
13.

Modification of the Orthosteric PPARγ Covalent Antagonist Scaffold Yields an Improved Dual-Site Allosteric Inhibitor.

Brust R, Lin H, Fuhrmann J, Asteian A, Kamenecka TM, Kojetin DJ.

ACS Chem Biol. 2017 Apr 21;12(4):969-978. doi: 10.1021/acschembio.6b01015. Epub 2017 Feb 16.

14.

Probing the Complex Binding Modes of the PPARγ Partial Agonist 2-Chloro-N-(3-chloro-4-((5-chlorobenzo[d]thiazol-2-yl)thio)phenyl)-4-(trifluoromethyl)benzenesulfonamide (T2384) to Orthosteric and Allosteric Sites with NMR Spectroscopy.

Hughes TS, Shang J, Brust R, de Vera IMS, Fuhrmann J, Ruiz C, Cameron MD, Kamenecka TM, Kojetin DJ.

J Med Chem. 2016 Nov 23;59(22):10335-10341. doi: 10.1021/acs.jmedchem.6b01340. Epub 2016 Nov 4.

15.

Response of microbial community structure and function to short-term biochar amendment in an intensively managed bamboo (Phyllostachys praecox) plantation soil: Effect of particle size and addition rate.

Chen J, Li S, Liang C, Xu Q, Li Y, Qin H, Fuhrmann JJ.

Sci Total Environ. 2017 Jan 1;574:24-33. doi: 10.1016/j.scitotenv.2016.08.190. Epub 2016 Sep 10.

PMID:
27621090
16.

Activity-Based Profiling Reveals a Regulatory Link between Oxidative Stress and Protein Arginine Phosphorylation.

Fuhrmann J, Subramanian V, Kojetin DJ, Thompson PR.

Cell Chem Biol. 2016 Aug 18;23(8):967-977. doi: 10.1016/j.chembiol.2016.07.008. Epub 2016 Aug 11.

17.

Branched-chain and aromatic amino acids, insulin resistance and liver specific ectopic fat storage in overweight to obese subjects.

Haufe S, Witt H, Engeli S, Kaminski J, Utz W, Fuhrmann JC, Rein D, Schulz-Menger J, Luft FC, Boschmann M, Jordan J.

Nutr Metab Cardiovasc Dis. 2016 Jul;26(7):637-642. doi: 10.1016/j.numecd.2016.03.013. Epub 2016 Apr 7.

PMID:
27134061
18.

Identification of a Binding Site for Unsaturated Fatty Acids in the Orphan Nuclear Receptor Nurr1.

de Vera IM, Giri PK, Munoz-Tello P, Brust R, Fuhrmann J, Matta-Camacho E, Shang J, Campbell S, Wilson HD, Granados J, Gardner WJ Jr, Creamer TP, Solt LA, Kojetin DJ.

ACS Chem Biol. 2016 Jul 15;11(7):1795-9. doi: 10.1021/acschembio.6b00037. Epub 2016 Apr 29.

19.

Assessment of human platelet survival in the NOD/SCID mouse model: technical considerations.

Fuhrmann J, Jouni R, Alex J, Zöllner H, Wesche J, Greinacher A, Bakchoul T.

Transfusion. 2016 Jun;56(6):1370-6. doi: 10.1111/trf.13602. Epub 2016 Apr 18.

PMID:
27086568
20.

Determining Solubility and Diffusivity by Using a Flow Cell Coupled to a Mass Spectrometer.

Khodayari M, Reinsberg P, Abd-El-Latif AE, Merdon C, Fuhrmann J, Baltruschat H.

Chemphyschem. 2016 Jun 3;17(11):1647-55. doi: 10.1002/cphc.201600005. Epub 2016 Mar 31.

PMID:
27017297
21.

Ebselen, a Small-Molecule Capsid Inhibitor of HIV-1 Replication.

Thenin-Houssier S, de Vera IM, Pedro-Rosa L, Brady A, Richard A, Konnick B, Opp S, Buffone C, Fuhrmann J, Kota S, Billack B, Pietka-Ottlik M, Tellinghuisen T, Choe H, Spicer T, Scampavia L, Diaz-Griffero F, Kojetin DJ, Valente ST.

Antimicrob Agents Chemother. 2016 Mar 25;60(4):2195-208. doi: 10.1128/AAC.02574-15. Print 2016 Apr.

22.

Spatial distribution and variability of carbon storage in different sympodial bamboo species in China.

Teng J, Xiang T, Huang Z, Wu J, Jiang P, Meng C, Li Y, Fuhrmann JJ.

J Environ Manage. 2016 Mar 1;168:46-52. doi: 10.1016/j.jenvman.2015.11.034. Epub 2015 Dec 13.

PMID:
26696605
23.

Protein Arginine Methylation and Citrullination in Epigenetic Regulation.

Fuhrmann J, Thompson PR.

ACS Chem Biol. 2016 Mar 18;11(3):654-68. doi: 10.1021/acschembio.5b00942. Epub 2015 Dec 31.

24.

Synthesis and Use of a Phosphonate Amidine to Generate an Anti-Phosphoarginine-Specific Antibody.

Fuhrmann J, Subramanian V, Thompson PR.

Angew Chem Int Ed Engl. 2015 Dec 1;54(49):14715-8. doi: 10.1002/anie.201506737. Epub 2015 Oct 12.

25.

Target temperature management of 33 degrees C exerts beneficial haemodynamic effects after out-of-hospital cardiac arrest.

Forkmann M, Kolschmann S, Holzhauser L, Ibrahim K, Guenther M, Christoph M, Fuhrmann JT, Boscheri A, Schmeiβer A, Strasser RH, Wunderlich C.

Acta Cardiol. 2015 Aug;70(4):451-9.

PMID:
26455248
26.

Dynamics of autochthonous soil viral communities parallels dynamics of host communities under nutrient stimulation.

Srinivasiah S, Lovett J, Ghosh D, Roy K, Fuhrmann JJ, Radosevich M, Wommack KE.

FEMS Microbiol Ecol. 2015 Jul;91(7). pii: fiv063. doi: 10.1093/femsec/fiv063. Epub 2015 Jul 6.

PMID:
26149131
27.

Chemical biology of protein arginine modifications in epigenetic regulation.

Fuhrmann J, Clancy KW, Thompson PR.

Chem Rev. 2015 Jun 10;115(11):5413-61. doi: 10.1021/acs.chemrev.5b00003. Epub 2015 May 13. Review. No abstract available.

28.

Caffeine-induced increase in voluntary activation and strength of the quadriceps muscle during isometric, concentric and eccentric contractions.

Behrens M, Mau-Moeller A, Weippert M, Fuhrmann J, Wegner K, Skripitz R, Bader R, Bruhn S.

Sci Rep. 2015 May 13;5:10209. doi: 10.1038/srep10209.

29.

Recommendations for the use of the non-obese diabetic/severe combined immunodeficiency mouse model in autoimmune and drug-induced thrombocytopenia: communication from the SSC of the ISTH.

Bakchoul T, Fuhrmann J, Chong BH, Bougie D, Aster R; Subcommittee on Platelet Immunology.

J Thromb Haemost. 2015 May;13(5):872-5. doi: 10.1111/jth.12879. Epub 2015 Mar 28. No abstract available.

30.

Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design.

Slade DJ, Fang P, Dreyton CJ, Zhang Y, Fuhrmann J, Rempel D, Bax BD, Coonrod SA, Lewis HD, Guo M, Gross ML, Thompson PR.

ACS Chem Biol. 2015 Apr 17;10(4):1043-53. doi: 10.1021/cb500933j. Epub 2015 Jan 26.

31.

Protein arginine methyltransferase 5 catalyzes substrate dimethylation in a distributive fashion.

Wang M, Fuhrmann J, Thompson PR.

Biochemistry. 2014 Dec 23;53(50):7884-92. doi: 10.1021/bi501279g. Epub 2014 Dec 8.

PMID:
25485739
32.

Gender differences in patients with cardiogenic shock complicating myocardial infarction: a substudy of the IABP-SHOCK II-trial.

Fengler K, Fuernau G, Desch S, Eitel I, Neumann FJ, Olbrich HG, de Waha A, de Waha S, Richardt G, Hennersdorf M, Empen K, Hambrecht R, Fuhrmann J, Böhm M, Poess J, Strasser R, Schneider S, Schuler G, Werdan K, Zeymer U, Thiele H.

Clin Res Cardiol. 2015 Jan;104(1):71-8. doi: 10.1007/s00392-014-0767-2. Epub 2014 Oct 7.

PMID:
25287767
33.

Chasing Phosphoarginine Proteins: Development of a Selective Enrichment Method Using a Phosphatase Trap.

Trentini DB, Fuhrmann J, Mechtler K, Clausen T.

Mol Cell Proteomics. 2014 Aug;13(8):1953-64. doi: 10.1074/mcp.O113.035790. Epub 2014 May 13.

34.

Quantitative phosphoproteomics reveals the role of protein arginine phosphorylation in the bacterial stress response.

Schmidt A, Trentini DB, Spiess S, Fuhrmann J, Ammerer G, Mechtler K, Clausen T.

Mol Cell Proteomics. 2014 Feb;13(2):537-50. doi: 10.1074/mcp.M113.032292. Epub 2013 Nov 20.

35.

Incidence of adverse cardiac events 5 years after polymer-free sirolimus eluting stent implantation: Results from the prospective Bad Berka Yukon Choice™ registry.

Ohlow MA, von Korn H, Gunkel O, Farah A, Fuhrmann JT, Lauer B.

Catheter Cardiovasc Interv. 2014 Dec 1;84(7):1080-6. doi: 10.1002/ccd.25272. Epub 2013 Nov 12.

PMID:
24217949
36.

ClC-7 expression levels critically regulate bone turnover, but not gastric acid secretion.

Supanchart C, Wartosch L, Schlack C, Kühnisch J, Felsenberg D, Fuhrmann JC, de Vernejoul MC, Jentsch TJ, Kornak U.

Bone. 2014 Jan;58:92-102. doi: 10.1016/j.bone.2013.09.022. Epub 2013 Oct 5.

PMID:
24103576
37.

Targeting the arginine phosphatase YwlE with a catalytic redox-based inhibitor.

Fuhrmann J, Subramanian V, Thompson PR.

ACS Chem Biol. 2013 Sep 20;8(9):2024-32. doi: 10.1021/cb4001469. Epub 2013 Jul 9.

PMID:
23838530
38.

Direct assessment of viral diversity in soils by random PCR amplification of polymorphic DNA.

Srinivasiah S, Lovett J, Polson S, Bhavsar J, Ghosh D, Roy K, Fuhrmann JJ, Radosevich M, Wommack KE.

Appl Environ Microbiol. 2013 Sep;79(18):5450-7. doi: 10.1128/AEM.00268-13. Epub 2013 Jun 21.

39.

Structural basis for recognizing phosphoarginine and evolving residue-specific protein phosphatases in gram-positive bacteria.

Fuhrmann J, Mierzwa B, Trentini DB, Spiess S, Lehner A, Charpentier E, Clausen T.

Cell Rep. 2013 Jun 27;3(6):1832-9. doi: 10.1016/j.celrep.2013.05.023. Epub 2013 Jun 13.

40.

Chemical and biological methods to detect post-translational modifications of arginine.

Slade DJ, Subramanian V, Fuhrmann J, Thompson PR.

Biopolymers. 2014 Feb;101(2):133-43. doi: 10.1002/bip.22256. Review.

41.

Giant right coronary artery aneurysm with a huge intramural thrombus.

Daralammouri Y, Fuhrmann J, Kunze T.

J Thorac Cardiovasc Surg. 2013 Nov;146(5):1290-1. doi: 10.1016/j.jtcvs.2013.02.065. Epub 2013 Mar 21. No abstract available.

42.

Intraaortic balloon support for myocardial infarction with cardiogenic shock.

Thiele H, Zeymer U, Neumann FJ, Ferenc M, Olbrich HG, Hausleiter J, Richardt G, Hennersdorf M, Empen K, Fuernau G, Desch S, Eitel I, Hambrecht R, Fuhrmann J, Böhm M, Ebelt H, Schneider S, Schuler G, Werdan K; IABP-SHOCK II Trial Investigators.

N Engl J Med. 2012 Oct 4;367(14):1287-96. doi: 10.1056/NEJMoa1208410. Epub 2012 Aug 26.

43.

Impact of short-term intake of red wine and grape polyphenol extract on the human metabolome.

Jacobs DM, Fuhrmann JC, van Dorsten FA, Rein D, Peters S, van Velzen EJ, Hollebrands B, Draijer R, van Duynhoven J, Garczarek U.

J Agric Food Chem. 2012 Mar 28;60(12):3078-85. doi: 10.1021/jf2044247. Epub 2012 Mar 13.

PMID:
22372405
44.

Anti-idiotypic Fab Fragments Image a Conserved N-terminal Epitope Patch of Grass Pollen Allergen Phl p 1.

Lukschal A, Fuhrmann J, Sobanov J, Neumann D, Wallmann J, Knittelfelder R, Hemmer W, Scheiner O, Vogel M, Stadler BM, Jensen-Jarolim E, Szalai K.

Open Allergy J. 2011 May 23;4:16-23.

45.

Incidence and predictors of ventricular arrhythmias after ST-segment elevation myocardial infarction.

Ohlow MA, Geller JC, Richter S, Farah A, Müller S, Fuhrmann JT, Lauer B.

Am J Emerg Med. 2012 May;30(4):580-6. doi: 10.1016/j.ajem.2011.02.029. Epub 2011 May 12.

PMID:
21570242
46.

Prevalence and spectrum of coronary artery anomalies in patients with an isolated congenital left ventricular aneurysm or diverticulum.

Ohlow MA, Fuhrmann JT, Lauer B.

Clin Cardiol. 2011 Apr;34(4):226-32. doi: 10.1002/clc.20875. Epub 2011 Feb 11.

47.

Distinct neuropathologic phenotypes after disrupting the chloride transport proteins ClC-6 or ClC-7/Ostm1.

Pressey SN, O'Donnell KJ, Stauber T, Fuhrmann JC, Tyynelä J, Jentsch TJ, Cooper JD.

J Neuropathol Exp Neurol. 2010 Dec;69(12):1228-46. doi: 10.1097/NEN.0b013e3181ffe742.

PMID:
21107136
48.

A new Lamarckian genetic algorithm for flexible ligand-receptor docking.

Fuhrmann J, Rurainski A, Lenhof HP, Neumann D.

J Comput Chem. 2010 Jul 15;31(9):1911-8. doi: 10.1002/jcc.21478.

PMID:
20082382
49.

Determinants of exercise-induced fat oxidation in obese women and men.

Haufe S, Engeli S, Budziarek P, Utz W, Schulz-Menger J, Hermsdorf M, Wiesner S, Otto C, Fuhrmann JC, Luft FC, Boschmann M, Jordan J.

Horm Metab Res. 2010 Mar;42(3):215-21. doi: 10.1055/s-0029-1242745. Epub 2009 Nov 23.

PMID:
19937568
50.

Metabolite profiling identifies candidate markers reflecting the clinical adaptations associated with Roux-en-Y gastric bypass surgery.

Mutch DM, Fuhrmann JC, Rein D, Wiemer JC, Bouillot JL, Poitou C, Clément K.

PLoS One. 2009 Nov 19;4(11):e7905. doi: 10.1371/journal.pone.0007905.

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