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Items: 14


Unresolved recombination intermediates lead to ultra-fine anaphase bridges, chromosome breaks and aberrations.

Chan YW, Fugger K, West SC.

Nat Cell Biol. 2018 Jan;20(1):92-103. doi: 10.1038/s41556-017-0011-1. Epub 2017 Dec 18.


Keeping homologous recombination in check.

Fugger K, West SC.

Cell Res. 2016 Apr;26(4):397-8. doi: 10.1038/cr.2016.25. Epub 2016 Feb 23.


The PCNA-associated protein PARI negatively regulates homologous recombination via the inhibition of DNA repair synthesis.

Burkovics P, Dome L, Juhasz S, Altmannova V, Sebesta M, Pacesa M, Fugger K, Sorensen CS, Lee MY, Haracska L, Krejci L.

Nucleic Acids Res. 2016 Apr 20;44(7):3176-89. doi: 10.1093/nar/gkw024. Epub 2016 Jan 20.


FBH1 Catalyzes Regression of Stalled Replication Forks.

Fugger K, Mistrik M, Neelsen KJ, Yao Q, Zellweger R, Kousholt AN, Haahr P, Chu WK, Bartek J, Lopes M, Hickson ID, Sørensen CS.

Cell Rep. 2015 Mar 17;10(10):1749-1757. doi: 10.1016/j.celrep.2015.02.028. Epub 2015 Mar 12.


FBH1 co-operates with MUS81 in inducing DNA double-strand breaks and cell death following replication stress.

Fugger K, Chu WK, Haahr P, Kousholt AN, Beck H, Payne MJ, Hanada K, Hickson ID, Sørensen CS.

Nat Commun. 2013;4:1423. doi: 10.1038/ncomms2395.


LEDGF (p75) promotes DNA-end resection and homologous recombination.

Daugaard M, Baude A, Fugger K, Povlsen LK, Beck H, Sørensen CS, Petersen NH, Sorensen PH, Lukas C, Bartek J, Lukas J, Rohde M, Jäättelä M.

Nat Struct Mol Biol. 2012 Aug;19(8):803-10. doi: 10.1038/nsmb.2314. Epub 2012 Jul 8.


CtIP-dependent DNA resection is required for DNA damage checkpoint maintenance but not initiation.

Kousholt AN, Fugger K, Hoffmann S, Larsen BD, Menzel T, Sartori AA, Sørensen CS.

J Cell Biol. 2012 Jun 25;197(7):869-76. doi: 10.1083/jcb.201111065.


SET8 is degraded via PCNA-coupled CRL4(CDT2) ubiquitylation in S phase and after UV irradiation.

Jørgensen S, Eskildsen M, Fugger K, Hansen L, Larsen MS, Kousholt AN, Syljuåsen RG, Trelle MB, Jensen ON, Helin K, Sørensen CS.

J Cell Biol. 2011 Jan 10;192(1):43-54. doi: 10.1083/jcb.201009076.


HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes.

Bekker-Jensen S, Rendtlew Danielsen J, Fugger K, Gromova I, Nerstedt A, Lukas C, Bartek J, Lukas J, Mailand N.

Nat Cell Biol. 2010 Jan;12(1):80-6; sup pp 1-12. doi: 10.1038/ncb2008. Epub 2009 Dec 20. Erratum in: Nat Cell Biol. 2010 Apr;12(4):412. Lukas, Claudia [added].


Human Fbh1 helicase contributes to genome maintenance via pro- and anti-recombinase activities.

Fugger K, Mistrik M, Danielsen JR, Dinant C, Falck J, Bartek J, Lukas J, Mailand N.

J Cell Biol. 2009 Sep 7;186(5):655-63. doi: 10.1083/jcb.200812138.


Where I would want to die.

Fugger K.

J Palliat Med. 2009 Mar;12(3):267-8. doi: 10.1089/jpm.2009.9655. No abstract available.


Human Xip1 (C2orf13) is a novel regulator of cellular responses to DNA strand breaks.

Bekker-Jensen S, Fugger K, Danielsen JR, Gromova I, Sehested M, Celis J, Bartek J, Lukas J, Mailand N.

J Biol Chem. 2007 Jul 6;282(27):19638-43. Epub 2007 May 16.


Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints.

Bartkova J, Rezaei N, Liontos M, Karakaidos P, Kletsas D, Issaeva N, Vassiliou LV, Kolettas E, Niforou K, Zoumpourlis VC, Takaoka M, Nakagawa H, Tort F, Fugger K, Johansson F, Sehested M, Andersen CL, Dyrskjot L, Ørntoft T, Lukas J, Kittas C, Helleday T, Halazonetis TD, Bartek J, Gorgoulis VG.

Nature. 2006 Nov 30;444(7119):633-7.


Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage.

Syljuåsen RG, Sørensen CS, Hansen LT, Fugger K, Lundin C, Johansson F, Helleday T, Sehested M, Lukas J, Bartek J.

Mol Cell Biol. 2005 May;25(9):3553-62.

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